Panthera leo (lion): 122221689
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Entry
122221689 CDS
T10741
Symbol
LRRK1
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 1 isoform X1
KO
K08843
leucine-rich repeat kinase 1 [EC:
2.7.11.1
]
Organism
plez Panthera leo (lion)
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plez01001
]
122221689 (LRRK1)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
122221689 (LRRK1)
Protein kinases [BR:
plez01001
]
Serine/threonine kinases: TKL group
LRRK family
122221689 (LRRK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
LRR_8
COR-B
LRR_4
COR-A
Roc
Ank_2
Ank
LRR_1
Arf
LRR_14
LRR_EndoS
Ank_KRIT1
Ras
LRR_LRWD1
Ank_4
Beta-prop_LRRK2
PROPPIN
MMR_HSR1
Gtr1_RagA
TniB
Motif
Other DBs
NCBI-GeneID:
122221689
NCBI-ProteinID:
XP_042797117
UniProt:
A0A8C8WDQ6
LinkDB
All DBs
Position
B3:19041671..19190588
Genome browser
AA seq
2017 aa
AA seq
DB search
MAGMSRRPPSMYWCVGPEGSAVCPERAMETHNGAGDMGSKPSTPGSDPTARCPGTEGIHA
AYKQGDPSRARHLLREACDDSTSQLEKGRLLSISAAYGDLETVRYLLTERRVELPTEPTD
DNPAVVAAHFGHTDVVQELLESLPGACSPQRLLNWMLALACQRGHLGVVKLLVLTHGADP
ESYAVRKNEFPVIVRLPLYAAIKSGNEDIAIFLLRHGAFFCSYILLDSPDPSKHLLRKYF
IEASTLSSNCPGKMALRVKWSHLKLPWVDLDWLIDISCQITELDLSANCLSSLPSVIPWG
LINLRKLNLSNNHLGELPGVQSSDEIICSRLLEIDISSNKLPHLPPGFLHLLKLQKLTAS
KNYLEKLFEEESATNWIGLRKLQELDISNNKLTELPALFLHSFKSLSYLNVSRNNLKVFP
DAWACPLKCCRASKNALESLPDKMAVFWKNHLRDADFSENALKEVPLGLFQLDALMFLRL
QGNQLMVLPPQDKWTCRQLKTLDLSRNQFGKNEDGLKTKRISFFTTRGRQRSGTETAGVL
EFPAFLSESLEVLCLNDNHLDAVPPSVCLLKNLSELYLGNNPGLRELPPELGQLGNLWQL
DIEDLNISNVPTEIRKEGPKAMLSYLRAQLRKAEKCKLMKMIIVGPPRQGKSTLLEILQT
GRAPQVVHSEATIRTTKWELQRPAGSRAKVESVEFTVWDIGGPASMATVNQCFFTDKALY
VVVWNLALGEEAVANLQFWLLNIEAKAPNAVVLVVGTHLDLIETKFRVERIATLRAYVLA
LCRSPSGSRATGFPDITFKHLHELSCKSLEGQEGLRQLIFHVTCNMKDVGSTIGCQRLAG
RLIPRSYLSLQEAVLAEQQRRSLSDDVQYLTDRQLEQLVEQTPDNDIKDYEDLQSAISFL
IETGTLLHFPDTSHGLRNLYFLDPIWLSECLQRIFNIKGSRSVAKNGVIRAEDLRMLLVG
TGFTQQTEEQYFQFLAKFEIALPVANDSYLLPHLLPSKPGLDTHGMRHPKANTIQRVFKM
SFVPVGFWQRFIARMLISLAEMDLQLFENKKNTKSRHRKVTIYSFTGNQRNRCSTFRVKR
NQTIYWQEGLLVTFDGGYLSVESSDVNWKKKKSGGIKIICQSEMRDFSAMAFITDHVNSL
IDQWFPALTATESDGTPLMEQYVPCPVCETSWAQHTDPSEKSEGVQYFDMEDCVLTAIEQ
DFISCPRHPDLPVPLQELVPELFMTDFPARLFLENSKLEHSEDESSVLGQGGSGTIIYRA
RYQGQPVAVKRFQIKKFKNFANAPADTMLRHLRATDAMKNFSEFRQEASMLHALQHPCIV
SLIGISIHPLCFALELAPLGSLNTVLSENARDSSFMPLGHMLTQKIAYQIASGLAYLHKK
NIIFCDLKSDNILVWSLDVKDHINIKLSDYGISRQSFHEGALGVEGTPGYQAPEIRPRIV
YDEKVDMFSYGMVLYELLSGQRPALGHHQLQIAKKLSKGIRPVLGQPEEVQFHRLQALMM
ECWDTKPEKRPLALSVVSQMKDPTFATFMYQLPCGKQTAFFSSQGQEYMVVFWDGKEESR
NYTVVNTEKGLMEVQRMSCAGMTLSCQLKVQNSLWTATEDQKIYIYSLKGMCPLNTPQRA
LDTPAVVTCLLAVPVIKKNSYLVLAGLADGLVAVFPVVRGAPDDSCSYLCSHTANRSKFS
IPDEDTRQNPYPVKAMEVVNSGSEVWYSNGPGLLVIDCVALEISRRLEPYSAPSVVTSVV
GSSECRGEEVVWCLDDRANSLVMYHAATYQLCARYFCGDPSPLRDMFPVCPLGPEPRGGH
TASPKEPKGDSIADVSIMYSEELGTQILTHQDSLTDYCSTSSSSSSPHRAPRSSSSLPCS
PASSASVPFAANYEDSDRLHEPTAGSDRSEHDLTPVDGEAFSQHLQAVRILAVKDVIWVP
RRGGDVIVIGLEKDAGGQRGRVIAVLKARELTPRGALVDAAVVAKDTVVCGFENENMEWC
LAVWRGWGTREFDVFYHSYEELGRLEACMRKRRVLCS
NT seq
6054 nt
NT seq
+upstream
nt +downstream
nt
atggctggcatgtctcggcgaccgcccagcatgtactggtgtgtgggtccagagggctca
gctgtgtgtccagaacgtgccatggagacccataatggtgctggggacatgggcagcaaa
ccgtccacaccaggcagtgaccccacagcgcggtgcccggggacggagggcattcacgct
gcatacaagcaaggagaccccagcagggcccggcacttgctccgggaggcttgtgatgac
agcacatcccagctggagaagggccggctcctgagcatctcagcggcctatggggatctg
gagactgtccgataccttctcaccgagagacgggtggagctgcccacggagcccaccgat
gacaacccagctgtggtggcagcgcattttgggcacactgacgtggtgcaggaattgctt
gaatctttgccaggtgcctgcagcccccagaggctgctgaactggatgctggccttggct
tgccaaagagggcatctgggggtggtgaagctcctggtcctgacacacggggccgacccg
gaaagctacgctgtcaggaagaacgagtttcctgtcattgtgcgcttgcccctctatgca
gccatcaagtcaggaaatgaagacatcgccatattcctgcttcggcatggggccttcttc
tgttcctacatcttattggacagtcctgaccccagcaaacatctcctcaggaagtacttc
attgaggctagcaccttgtccagcaactgtccgggaaaaatggcgctgcgtgtgaaatgg
tcccatctcaagttgccctgggtggatctagactggctcatagacatctcctgccagatc
acagagctggacctttctgccaattgcctgtcttccctcccctccgtcatcccctgggga
ctcatcaacctccggaagctgaacctctccaacaaccacctgggggagctgcctggcgtg
cagtcatcggatgaaatcatctgttccaggctcctggaaattgacatttccagcaataaa
ttgccccatctcccaccaggattcttgcacctcttaaaacttcaaaaattgacagcttca
aaaaactacttggaaaagttgtttgaagaagaaagtgccactaactggatcggtttgcgg
aagctgcaggaactcgacatctctaacaataaattgacggaactccctgccctttttctt
cattctttcaagtcactcagttatctgaatgtctccagaaataacctgaaggtgtttcca
gatgcctgggcctgccctttgaaatgttgtagagcatccaaaaatgccctggaatctcta
ccagacaaaatggctgtcttttggaaaaaccacctcagggatgcggatttctcagaaaac
gctctcaaagaagtccccctggggcttttccagctcgatgccctcatgttcctgaggtta
caggggaaccagctcatggtgctgccacctcaagataagtggacctgtagacaacttaaa
accctggatctctccagaaaccaatttggcaaaaatgaagacggacttaaaacaaagcgt
atttcctttttcaccaccagagggcgccagcgttctgggacggagacagccggtgtgctg
gaatttccggccttcctaagtgagtctttggaggtcctttgtctgaacgacaatcatctg
gatgcagtccctccctcggtttgcctactgaagaacttatcagaactctacttgggaaac
aatcctggcctccgagaactccctcctgagctggggcagctgggcaacctttggcagttg
gacattgaagacctgaacatcagcaacgtgcccacggagatcagaaaggaaggccccaaa
gcgatgttgtcttacctgcgcgctcagctgcggaaagcagagaagtgcaagctgatgaaa
atgatcatcgtgggtcctccgcgccagggcaagtccaccctcctggagatcttacagacg
gggagggccccccaggtggtgcacagcgaggccaccatcaggaccaccaagtgggagctc
cagaggccagctggctcgagagccaaggttgagtccgtggaattcaccgtctgggacatc
ggtggccccgccagcatggccactgtcaatcagtgcttcttcacagacaaggccctgtat
gtggtggtctggaacctagcactgggggaggaggccgtggccaacctccagttctggctg
ctcaacatcgaggccaaggcccccaacgctgtggtgctggtggttggaacacacctggac
ttaatcgaaaccaaattccgagtggagagaatcgcaaccctgcgcgcctatgtgctggcg
ttgtgccgttcgccctccgggtccagggccacgggcttcccggacatcaccttcaaacac
ttacacgaactctcctgcaagagtctggaaggccaggaagggctacggcagctgatcttc
cacgtcacgtgcaacatgaaggatgtgggcagcaccataggctgccagagactcgcgggg
aggctgatccccaggagctacctgagcctccaggaggcagtgctggctgagcagcagcgc
cgaagcctgagcgacgacgtgcagtacctgacggacaggcagctggagcagctggtggag
cagacaccagacaacgacatcaaagactatgaggacctgcagtccgccatcagcttcctc
atagagaccggcacactgctgcacttcccggacaccagccacggcctgaggaacctctac
ttcctcgaccccatttggctgtccgaatgtctgcagaggatcttcaacatcaagggctcc
cgctcagtggccaagaacggggtgatccgggccgaggacctcaggatgctgctggtgggg
accggcttcacacagcagacagaggagcagtacttccagttcctggccaagttcgagatc
gccctgccggtggccaacgacagctatcttctgccacacctccttccgtccaaacccggc
ctggacactcacggcatgcgacaccccaaggccaataccattcagagagtgtttaagatg
agcttcgttcctgttggcttctggcaaaggtttatagcacggatgctgatcagcctggcg
gagatggacctccagctttttgaaaacaagaagaatactaaaagcagacacaggaaagtc
accatttatagttttacaggaaaccagagaaatcgctgcagtacgttcagagtgaaaaga
aatcagaccatctattggcaggaagggctcctggtcacttttgatgggggctacctcagt
gtggaatcctcggacgtgaactggaaaaagaaaaaaagtggaggaataaaaatcatttgc
cagtcagaaatgagggacttctctgcaatggcttttatcacagaccatgtcaattccttg
atcgatcagtggtttcctgccctgacagccacagaaagcgacgggaccccactcatggag
cagtacgtcccctgcccagtctgcgagacctcctgggcccagcacaccgacccaagtgag
aaatcagagggcgtacagtacttcgacatggaagactgcgtgctgacagccattgagcag
gacttcatctcctgccccagacaccctgacctccccgtgcctctccaggagctggttcct
gagctgttcatgactgacttcccggccaggctcttcctggagaacagcaagttggagcac
agcgaggatgagagcagtgtcctgggtcaaggtgggagcggcaccatcatctaccgggcc
cggtaccaaggccagcccgtggcagtgaagcgattccagatcaagaaattcaagaacttt
gccaacgccccagcagacaccatgctgaggcacctgcgggccacggacgccatgaagaac
ttctcggagttccggcaagaggccagcatgctacacgccctgcagcacccctgtattgtg
tccctcatcggcatcagcatccacccgctctgcttcgccctggagctcgccccactgggt
agcctcaacaccgtgctgtcagagaatgccagagattcttcctttatgcccctgggacac
atgctcacccaaaaaatagcctaccagattgcctctggcctggcctacctgcacaagaaa
aacatcatcttctgtgacctgaagtcagacaacattctggtctggtctctggacgtcaag
gaccacatcaatatcaagctgtcggactacgggatctcacggcagtcatttcatgagggt
gccctcggcgtggagggcacacccggctaccaggccccagagatccgtcctcgcattgtg
tatgacgagaaggtagacatgttctcctatggaatggtgctctacgagttgctgtcgggg
cagcggccagcgctgggccaccaccagcttcagatcgccaagaagctgtccaagggcatc
cgtcctgttctggggcagcccgaggaggtgcagttccatcgcctgcaggcactcatgatg
gagtgctgggacacaaagcccgagaagcgcccactggccctgtcggtggtgagccagatg
aaggacccaacctttgcaacgttcatgtaccagctaccctgtgggaagcagacggccttc
ttctcatcccagggccaggagtacatggtggtgttctgggatgggaaagaggagtccagg
aactacacggtggtgaacacggagaagggcctcatggaggtgcagcggatgagctgtgcg
ggaatgacactaagctgccagctcaaggtccagaactctctgtggacggccactgaggac
cagaagatctacatctatagcctcaagggcatgtgcccgttaaacacaccccaacgggct
ttggacaccccggctgtcgtcacctgcttattggcagtgcctgttattaaaaagaattcc
tacctggtgttggcaggcctggccgacgggcttgtggcagtgtttcccgtggtgcggggt
gccccggacgacagctgctcctacctgtgctcacacacagccaacaggtccaagtttagc
atcccagatgaagacacacggcagaacccctaccccgtgaaggccatggaggtggtcaac
agcggctccgaggtctggtacagcaacgggcccggcctgctggtcatcgactgtgtggcc
ctggagatcagcaggaggctggagccctactcggccccttcggtggtcacctcggtcgtg
ggcagctccgagtgcaggggggaggaggtcgtctggtgcctggacgacagggccaactcc
ttggtgatgtaccatgcagctacctaccagctgtgcgcccggtacttctgcggggacccc
agcccgctcagagacatgtttcccgtgtgcccgttgggtccagagccccgtggcggccac
acagccagccccaaagagcccaagggggactccatcgcggacgtgagcatcatgtacagc
gaggagctgggcacgcagatcctgacccaccaggactcgctgactgactactgctccacg
tcctcctcctcatcctccccccaccgggcccccaggtcgtcctcaagcctgccctgctcc
ccggcaagctctgccagcgtgcctttcgccgccaactacgaggactccgacaggctgcac
gagcccaccgcgggctccgacaggtctgagcatgacctgacccccgtggacggggaggct
ttcagccagcacctgcaggccgtgaggatcctagctgtgaaagacgtcatctgggtcccc
aggcgcggcggcgatgttatcgtcatcggcctggagaaggacgccggaggccagcggggc
cgtgtcatcgccgtcttaaaagcccgcgagctgactccgcgtggggcgcttgtggatgcg
gccgtggtggcaaaggacacggttgtgtgtggctttgagaacgaaaacatggagtggtgc
ctggctgtctggaggggctggggcaccagagagtttgatgttttctaccactcctacgaa
gagctgggccggctggaggcttgcatgcggaagagaagggtcctctgctcctga
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integrated database retrieval system