KEGG   Panthera leo (lion): 122221873
Entry
122221873         CDS       T10741                                 
Symbol
CALML4
Name
(RefSeq) calmodulin-like protein 4 isoform X1
  KO
K02183  calmodulin
Organism
plez  Panthera leo (lion)
Pathway
plez04014  Ras signaling pathway
plez04015  Rap1 signaling pathway
plez04020  Calcium signaling pathway
plez04022  cGMP-PKG signaling pathway
plez04024  cAMP signaling pathway
plez04070  Phosphatidylinositol signaling system
plez04114  Oocyte meiosis
plez04218  Cellular senescence
plez04261  Adrenergic signaling in cardiomyocytes
plez04270  Vascular smooth muscle contraction
plez04371  Apelin signaling pathway
plez04625  C-type lectin receptor signaling pathway
plez04713  Circadian entrainment
plez04720  Long-term potentiation
plez04722  Neurotrophin signaling pathway
plez04728  Dopaminergic synapse
plez04740  Olfactory transduction
plez04744  Phototransduction
plez04750  Inflammatory mediator regulation of TRP channels
plez04910  Insulin signaling pathway
plez04912  GnRH signaling pathway
plez04915  Estrogen signaling pathway
plez04916  Melanogenesis
plez04921  Oxytocin signaling pathway
plez04922  Glucagon signaling pathway
plez04924  Renin secretion
plez04925  Aldosterone synthesis and secretion
plez04970  Salivary secretion
plez04971  Gastric acid secretion
plez05010  Alzheimer disease
plez05012  Parkinson disease
plez05022  Pathways of neurodegeneration - multiple diseases
plez05031  Amphetamine addiction
plez05034  Alcoholism
plez05133  Pertussis
plez05152  Tuberculosis
plez05163  Human cytomegalovirus infection
plez05167  Kaposi sarcoma-associated herpesvirus infection
plez05170  Human immunodeficiency virus 1 infection
plez05200  Pathways in cancer
plez05214  Glioma
plez05417  Lipid and atherosclerosis
plez05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:plez00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    122221873 (CALML4)
   04015 Rap1 signaling pathway
    122221873 (CALML4)
   04371 Apelin signaling pathway
    122221873 (CALML4)
   04020 Calcium signaling pathway
    122221873 (CALML4)
   04070 Phosphatidylinositol signaling system
    122221873 (CALML4)
   04024 cAMP signaling pathway
    122221873 (CALML4)
   04022 cGMP-PKG signaling pathway
    122221873 (CALML4)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    122221873 (CALML4)
   04218 Cellular senescence
    122221873 (CALML4)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    122221873 (CALML4)
  09152 Endocrine system
   04910 Insulin signaling pathway
    122221873 (CALML4)
   04922 Glucagon signaling pathway
    122221873 (CALML4)
   04912 GnRH signaling pathway
    122221873 (CALML4)
   04915 Estrogen signaling pathway
    122221873 (CALML4)
   04921 Oxytocin signaling pathway
    122221873 (CALML4)
   04916 Melanogenesis
    122221873 (CALML4)
   04924 Renin secretion
    122221873 (CALML4)
   04925 Aldosterone synthesis and secretion
    122221873 (CALML4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    122221873 (CALML4)
   04270 Vascular smooth muscle contraction
    122221873 (CALML4)
  09154 Digestive system
   04970 Salivary secretion
    122221873 (CALML4)
   04971 Gastric acid secretion
    122221873 (CALML4)
  09156 Nervous system
   04728 Dopaminergic synapse
    122221873 (CALML4)
   04720 Long-term potentiation
    122221873 (CALML4)
   04722 Neurotrophin signaling pathway
    122221873 (CALML4)
  09157 Sensory system
   04744 Phototransduction
    122221873 (CALML4)
   04740 Olfactory transduction
    122221873 (CALML4)
   04750 Inflammatory mediator regulation of TRP channels
    122221873 (CALML4)
  09159 Environmental adaptation
   04713 Circadian entrainment
    122221873 (CALML4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122221873 (CALML4)
  09162 Cancer: specific types
   05214 Glioma
    122221873 (CALML4)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    122221873 (CALML4)
   05163 Human cytomegalovirus infection
    122221873 (CALML4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122221873 (CALML4)
  09171 Infectious disease: bacterial
   05133 Pertussis
    122221873 (CALML4)
   05152 Tuberculosis
    122221873 (CALML4)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    122221873 (CALML4)
   05012 Parkinson disease
    122221873 (CALML4)
   05022 Pathways of neurodegeneration - multiple diseases
    122221873 (CALML4)
  09165 Substance dependence
   05031 Amphetamine addiction
    122221873 (CALML4)
   05034 Alcoholism
    122221873 (CALML4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    122221873 (CALML4)
   05418 Fluid shear stress and atherosclerosis
    122221873 (CALML4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:plez01009]
    122221873 (CALML4)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:plez04131]
    122221873 (CALML4)
   03036 Chromosome and associated proteins [BR:plez03036]
    122221873 (CALML4)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:plez04147]
    122221873 (CALML4)
Protein phosphatases and associated proteins [BR:plez01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Calcineurin (PPP3/ PP2B)
    Regulatory subunits
     122221873 (CALML4)
Membrane trafficking [BR:plez04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    122221873 (CALML4)
Chromosome and associated proteins [BR:plez03036]
 Eukaryotic type
  Centrosome formation proteins
   Centrosome duplication proteins
    Centriole replication proteins
     122221873 (CALML4)
Exosome [BR:plez04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   122221873 (CALML4)
SSDB
Motif
Pfam: EF-hand_7 EF-hand_8 EF-hand_6 EF-hand_1 EF-hand_9 AIF-1 CFAP251_C EF-hand_11 GPHH FlgD
Other DBs
NCBI-GeneID: 122221873
NCBI-ProteinID: XP_042797518
LinkDB
Position
B3:37158614..37170041
AA seq 231 aa
MSPGGALSAASFSPSETCRPGRAVAGHQLCSGKLESDPGTGPGLHGSRGFITGASTQLGG
LSTWSLEERDRTGGCGSREPTGDSLRPRDEYKECFSLYDKQQRGKIKATDLMVVMRCLGA
SPTPGEVQRHLQTHGIDRNGELDFSTFLTIMHTQIKQEDPKKEILLAMLMADKEKKGYIM
ASELRSKLMTLGEKLTHKEVDDLFREAEIEPNGKVKYDEFIDKITIPVQDY
NT seq 696 nt   +upstreamnt  +downstreamnt
atgagtcctgggggagccctttccgcagcctcattttctccaagtgaaacctgtcgccct
ggccgggcggtggcggggcatcagctgtgctcggggaagctggaatctgacccgggcact
gggcctggtctccatggcagccgcggatttattactggggcctccacccagcttggcgga
ctttcgacttggagcctggaggagagggacagaacaggcggttgtgggagccgggagccc
acaggcgacagcctgaggccccgcgatgagtacaaggaatgcttctctctgtatgacaag
cagcagcgggggaagataaaagccactgacctcatggtggtgatgaggtgcctgggggcc
agcccgacacctggagaggtgcagcggcacctgcagactcacgggatcgacagaaacggg
gagctggatttctccacgttcctgaccattatgcacacgcaaataaaacaagaggaccca
aagaaagaaatcctcttggccatgttgatggcagacaaggagaagaaaggctacatcatg
gcgtccgagctgcggtcaaaactcatgacactgggggagaagctcacccacaaggaagtg
gacgatcttttcagggaagcagagattgaaccaaatggcaaagtgaagtatgatgaattt
atcgacaagatcaccatccctgtgcaggactactga

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