Panthera leo (lion): 122222048
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Entry
122222048 CDS
T10741
Symbol
USP8
Name
(RefSeq) ubiquitin carboxyl-terminal hydrolase 8 isoform X1
KO
K11839
ubiquitin carboxyl-terminal hydrolase 8 [EC:
3.4.19.12
]
Organism
plez Panthera leo (lion)
Pathway
plez04137
Mitophagy - animal
plez04144
Endocytosis
plez04934
Cushing syndrome
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
122222048 (USP8)
04137 Mitophagy - animal
122222048 (USP8)
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
122222048 (USP8)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
plez01002
]
122222048 (USP8)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
plez04131
]
122222048 (USP8)
04121 Ubiquitin system [BR:
plez04121
]
122222048 (USP8)
Enzymes [BR:
plez01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.19 Omega peptidases
3.4.19.12 ubiquitinyl hydrolase 1
122222048 (USP8)
Peptidases and inhibitors [BR:
plez01002
]
Cysteine peptidases
Family C19: ubiquitin-specific protease family
122222048 (USP8)
Membrane trafficking [BR:
plez04131
]
Endosome - Lysosome transport
Others
Others
122222048 (USP8)
Ubiquitin system [BR:
plez04121
]
Deubiquitinating enzyme (DUB)
Ubiquitin-specific proteases (UBPs)
UBP/USP
122222048 (USP8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
UCH
USP8_dimer
WW_USP8
UCH_1
Rhodanese
Metallothio_Pro
Motif
Other DBs
NCBI-GeneID:
122222048
NCBI-ProteinID:
XP_042797981
LinkDB
All DBs
Position
B3:complement(53419355..53496646)
Genome browser
AA seq
1116 aa
AA seq
DB search
MPAVASVPKELYLSSSLKDLNKKTEVKPEKISTKNYVQSALKIFKTAEESRLDRDEERAY
VLYMKYVTVYNLIKKRPDFKQQQDYFHSILGLANIKKAIEEAERLSESLKLRYEEAEVRK
KLEEKDRQEEQLQKQKRQEAGREDGGTSNKSSLENVMDSRDKTQKINGEKSDKNETTEKG
AITAKELYTLMMDENISLIIMDARRMQDYQDSHISNSLSVPEEAISPGVTASWIEAKLPD
DSKDTWKKRGNVEYVVLLDWFSSTKDLQLGTTLRSLKDALFKWESKTVLRNEPLVLEGGY
DNWLLCYPQYTTNAKVTPPPRGKNEEVSISLDFTYPSLEESIPSKPTAQMPLPSVEINEN
TEFLNDQDERMAPLNVSTPIESIAASKSDVLPIIQPVPVVKNVPQVDRTKKPAVKLPEDH
RIKSENKDHEQQSSQDGKVVPDRSTKPVFPPPTAMLTDEEKARIHAETALLMEKNKQEKE
LREKQQEEQKEKLRREEQEQKVRKKQEAEESEITEKQQKAKEEMERRESEQAKKEDKETS
AKRGREITGIKRQSKSEHETTDAKKSAEDRGKRCPTPELQKKSVGDGPHASVAGDSNSGK
PVKIKGQPESGILKTGTFRENTEDTERNKAREPLTRARSEEMGRIVPGLPSGWAKFLDPI
TGTFRYYHSPTNTVHMYPPEMAPSSAPPATPPTHKAKPQIPAERDREPSKLKRSYSSPDI
TQAIQEEEKRKPTVTPTVNRENKPTCYPKAEITRLSASQIRNLNPVFGGSGPALTGLRNL
GNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQY
RYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRHKEENNDHLD
DFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKC
TLQDCLRLFSKEEKLTDNNRFYCSHCRTRRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQ
KLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFK
FDDHEVSDISISSVKSSAAYILFYTSLGPRATDVAT
NT seq
3351 nt
NT seq
+upstream
nt +downstream
nt
atgcctgctgtggcttcagttcccaaagaactctacctcagttcttcactaaaagacctc
aataagaagacagaagttaaaccagagaaaataagcacgaagaattatgtacagagtgcc
ctgaagatcttcaagacagcagaagaaagcagattagatcgtgatgaggaaagggcctat
gtactatatatgaaatatgtgactgtttataatcttatcaaaaaaaggcctgatttcaag
caacagcaggactactttcattcaatacttggacttgcaaacatcaaaaaagctattgaa
gaagctgaaagactctctgaaagccttaaactcagatatgaagaagctgaggttcgaaaa
aaacttgaagaaaaggacagacaggaggagcagctgcagaaacagaaaaggcaagaagca
ggaagagaggatggtggtacatcaaataaaagttccttggaaaatgtaatggattccaga
gacaaaacccaaaagataaatggtgaaaagagtgacaaaaatgagaccacagagaaaggg
gcaatcacagcgaaggagctatacacattgatgatggatgaaaacatcagcttgattata
atggatgctcgaagaatgcaggattatcaagattcccatatttcaaattctctcagtgtt
cctgaagaagccatcagtccaggagtcactgctagttggattgaagcaaaactcccagat
gattctaaagacacatggaagaagagggggaatgtggaatatgtggtacttcttgactgg
tttagttcaacaaaagatttacaacttggaacaactctacggagtctgaaagatgcactt
ttcaagtgggaaagcaaaactgtcctgcgcaatgagcctttggttttagaaggaggctat
gacaactggctactttgttatccccagtatacaacaaatgctaaagtcactccaccccca
cgaggcaagaatgaagaggtgtctatctcattggattttacttatccttcactggaagaa
tcaattccttctaaacctactgcccagatgccacttccttctgtagaaataaatgaaaat
acagaatttttaaatgatcaagatgagagaatggcaccactgaacgtatcaactccaatt
gagtcaattgctgcttctaaatctgatgttttacccataattcagccagtgcctgttgta
aagaatgttccacaggttgatcgtactaaaaaaccagcagtcaaattgcctgaagatcat
agaataaaatctgaaaataaagatcacgagcaacagtcttctcaggatggaaaagttgtt
cctgatcgctccacaaagccagtatttccccctccaactgccatgttaacagatgaagaa
aaagctcgtattcatgcagaaactgctcttctaatggagaaaaacaaacaagaaaaagaa
cttcgagaaaagcagcaagaagaacagaaagagaaactgaggagagaagaacaagaacaa
aaagtcagaaagaaacaagaagctgaagaaagtgaaatcaccgagaaacaacaaaaagca
aaagaagaaatggaaaggagagaaagtgaacaggccaagaaagaagataaggaaacctca
gcaaagaggggcagagaaataacaggaataaaaagacaaagtaaaagtgaacatgaaact
actgatgctaagaaatctgcagaagataggggtaaaaggtgtcccaccccagaactgcag
aaaaagtcagtgggagatggaccccatgcctctgtggcaggagattcaaattcaggcaag
cctgttaagattaaaggacaaccagaaagtggaattctaaagactggaacttttagagag
aatacagaagacactgaaaggaacaaagctcgagaacctttgacaagagcacgaagtgaa
gaaatggggaggatcgtaccaggactgccttcaggctgggccaagtttcttgacccaatc
actggaacttttcgttattatcattcacccaccaacactgttcatatgtatccaccggaa
atggctccttcatctgcacctcctgccacccctccaactcataaagccaagccacagatt
cctgctgagcgggatagggaaccgtccaaactgaagcgctcctactcctccccagatata
acccaggccattcaagaggaagagaagaggaagccaacagtaactccaacagttaatcgg
gaaaataagccaacgtgctaccctaaagctgagatcacaaggctttctgcttctcagatt
cggaacctcaatcctgtttttggaggatctggaccagctctcactggacttcgtaattta
ggaaatacttgctatatgaactcaatactgcagtgcctatgtaatgctccacatttggcc
gattatttcaaccgaaactgttaccaggacgatattaacaggtcaaatttgttggggcat
aaaggtgaagtggctgaagagtttggcataattatgaaagccctgtggacaggacagtac
aggtatatcagtccaaaagactttaaaatcaccattgggaagatcaatgaccagtttgca
ggatatagccagcaagattcacaagaactgcttctgttcctaatggatggactccatgaa
gatctaaataaagctgataatcggaagagacataaagaagaaaataatgatcaccttgat
gactttaaagctgcagagcatgcttggcagaaacataagcagctcaatgaatctattatt
gttgcactttttcagggtcagttcaaatccacagtacagtgcctcacctgtcacaaaaag
tctaggacatttgaggccttcatgtatttgtctctaccattagcttctacaagtaaatgt
acattacaggactgccttagattattttccaaagaagaaaagctcacagacaacaacagg
ttttactgcagtcattgcagaactcgacgggactctctaaaaaagatagagatctggaag
ttgccacctgtgcttttagtgcatctgaaacgtttttcctacgacggcaggtggaagcag
aaactacagacctctgtggatttcccattagagaatcttgacttgtcacagtatgttatt
ggtccaaagaacaatttgaagaaatataatttgttttctgtttcaaatcactatggtggg
ctggatggaggccactacactgcctattgtaaaaatgcagcgagacagcggtggtttaaa
tttgatgatcatgaagtttctgatatctccatttcttctgtgaagtcttcggcagcttat
atcctcttttatacttcattgggaccacgagcaactgatgtagccacgtaa
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