Panthera leo (lion): 122222140 Help Entry 122222140         CDS       T10741                                  Symbol PLA2G4F Name (RefSeq) cytosolic phospholipase A2 zeta   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism plez  Panthera leo (lion) Pathway plez00564   Glycerophospholipid metabolism plez00565   Ether lipid metabolism plez00590   Arachidonic acid metabolism plez00591   Linoleic acid metabolism plez00592   alpha-Linolenic acid metabolism plez01100   Metabolic pathways plez04010   MAPK signaling pathway plez04014   Ras signaling pathway plez04072   Phospholipase D signaling pathway plez04217   Necroptosis plez04270   Vascular smooth muscle contraction plez04370   VEGF signaling pathway plez04611   Platelet activation plez04664   Fc epsilon RI signaling pathway plez04666   Fc gamma R-mediated phagocytosis plez04724   Glutamatergic synapse plez04726   Serotonergic synapse plez04730   Long-term depression plez04750   Inflammatory mediator regulation of TRP channels plez04912   GnRH signaling pathway plez04913   Ovarian steroidogenesis plez04921   Oxytocin signaling pathway plez05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:plez00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     122222140 (PLA2G4F)    00565 Ether lipid metabolism     122222140 (PLA2G4F)    00590 Arachidonic acid metabolism     122222140 (PLA2G4F)    00591 Linoleic acid metabolism     122222140 (PLA2G4F)    00592 alpha-Linolenic acid metabolism     122222140 (PLA2G4F)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     122222140 (PLA2G4F)    04014 Ras signaling pathway     122222140 (PLA2G4F)    04370 VEGF signaling pathway     122222140 (PLA2G4F)    04072 Phospholipase D signaling pathway     122222140 (PLA2G4F)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     122222140 (PLA2G4F)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     122222140 (PLA2G4F)    04664 Fc epsilon RI signaling pathway     122222140 (PLA2G4F)    04666 Fc gamma R-mediated phagocytosis     122222140 (PLA2G4F)   09152 Endocrine system    04912 GnRH signaling pathway     122222140 (PLA2G4F)    04913 Ovarian steroidogenesis     122222140 (PLA2G4F)    04921 Oxytocin signaling pathway     122222140 (PLA2G4F)   09153 Circulatory system    04270 Vascular smooth muscle contraction     122222140 (PLA2G4F)   09156 Nervous system    04724 Glutamatergic synapse     122222140 (PLA2G4F)    04726 Serotonergic synapse     122222140 (PLA2G4F)    04730 Long-term depression     122222140 (PLA2G4F)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     122222140 (PLA2G4F)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     122222140 (PLA2G4F) Enzymes [BR:plez01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      122222140 (PLA2G4F) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  cPLA2_C2 PLA2_B C2 Motif Other DBs NCBI-GeneID:  122222140 NCBI-ProteinID:  XP_042798228 UniProt:  A0A8C8Y5W5 LinkDB All DBs Position B3:60796389..60810522 Genome browser AA seq 849 aa AA seqDB search MLWALWPRWLAGKGLPLLGAVLLRKRDKRGPQWRQWRRETHPYYDLQVKVLRARNIQGTD LLSKADCYVELRLPTASPSPAQTRMVANCSDPEWNETFHYQIHGAVKNVLELTLCDKDIL GSDQLSLLLFDLRSLKSGQPYRHIFPLNHQDSQELQVEFVLENSQVPASEVITNGVLVAQ PCLRIQGTLREGGTAPHREYGSRQIQLTVPGAYEKPQFLPLQPPMEGGLPATFTFHVNPV ISSRLDVELGERLTVLQSGPSAELEAHTNKLGEGGILLSSLALGQEEQRFVALGEGQEVV LSMKAEMSSGDLDLRLGFGLCDGEREFLDKRKQIVSKALQQVLGLSQVPDSGQVPVVAVL GSGGGTRAMSSLYGSLAGLQELGLLDTVTYLSGVSGSTWCISTLYKDPAWSQVALQGPIE RAQARVCSSKMGAMSTERLQYYAQELGTLESTGHRVSLIDIWGLLIEYFLYQEKNPAKLS DQQEAVNQGQNPYPIYASINVHTNISGEDFAEWCEFTPYEVGFPKYGAYVPTELFGSEFF MGHLLQPQPEPRICYLQGVWGSAFAASLDEIFLKTAGSGLSFLDCHRGSVNITDDCQKLQ LHDPTRLRTRLFTRQGPFSQAVLDIFTSRFTFAENCNFTRGLCLHKDYVAGREFMAWKDT HPDAFPNQLTPMRDCLCLVDGGFAINSPFPLSLLPQRAVDLILSFDYSLEAPFEVLQMTE KYCLDRGIPFPSIEVLPEDLEEPRECYLFAKAKDPRSPIVLHFPLVNRTFCTHLAPGVER QTAEEKAYGDFVVNGADTPYGMMNFTYEPEEFERLVALSRYNVLNNVETLRHALRLALER RQAGGRAGG NT seq 2550 nt NT seq  +upstreamnt  +downstreamnt atgctctgggcgctctggccaaggtggctggcaggcaaggggctgcccctcctgggggca gtgctgctgcggaagagagacaagaggggacctcagtggaggcaatggaggcgggaaacc cacccctactatgacctccaggtgaaggtgctgagggccagaaatatccagggcacagat ctcttgtccaaagctgactgctatgtggaactgcgcctgcccactgcatcccctagccct gcccagacaaggatggtggctaactgcagtgaccctgagtggaacgagaccttccactac cagatccatggtgctgtgaagaatgtcctggagctcaccctctgtgataaggacatcctg ggcagtgaccagctctccctgctactctttgacctgaggagcctcaagtctggccaaccc tacagacacatcttcccactcaaccaccaggattcacaggagctgcaggtggaatttgtt ctggagaacagccaggtgcctgcgtctgaagtcatcaccaatggagtcctggtggctcag ccctgtctgagaatccaggggaccctcagggaaggcgggacagccccacatcgagagtat ggctctaggcagattcagctgacagtgcccggggcctacgagaagccacagttcttgccc ctgcaacctcccatggagggaggcctcccagctaccttcacctttcacgtgaacccagtg atcagctccaggctggatgtggagctgggggagagactcacagtcctgcaaagtggtcca agtgctgagctggaggcccacaccaacaagctgggtgaggggggtatcctgctctcctct ctggccctaggccaagaggaacagcgctttgtggccctaggggagggccaggaggtggtt ctgagtatgaaggcagaaatgagctctggagaccttgacctgcgtcttggttttggcctg tgtgatggggaacgggagtttctggacaagaggaagcagatcgtgtccaaggccctgcaa caggttctgggattgagccaggtgcctgacagtggccaggtgcctgtggtggctgtgcta ggttcgggaggtggaacccgagccatgtcttccctgtacggcagcctggcagggctacag gaacttggcctcctggacactgtgacctacctgagtggggtctctggatctacctggtgc atttccacactctacaaggacccagcctggtcccaggtggccttgcagggccccattgag cgtgcccaggctcgggtctgcagcagtaagatgggggcgatgtccacagaacgcctacaa tactatgcccaggaactggggaccctggaaagcactggccacagagtttccctcatcgac atctggggtctcctcattgaatatttcctctaccaggagaaaaaccctgccaagctgtct gaccagcaggaggccgtcaaccagggccagaacccttatcctatctacgccagcatcaat gtccacaccaacatcagtggggaagacttcgcagaatggtgcgagttcacaccctatgag gtcggcttccccaagtacggggcttatgttcccactgagctctttggctctgagttcttc atggggcatctgctgcagccccagcccgagccccggatctgctacctgcagggtgtgtgg ggcagcgcctttgcagccagcctggatgagatcttcctgaagactgccggctcgggcctc agcttcctagactgccacagagggagtgtaaacatcacagatgactgccagaagctccag ctgcacgatcccacacgtctgaggaccaggctcttcacccgccaggggcccttctcccag gccgtgctggacatcttcacctcccgctttaccttcgcggagaactgtaatttcaccagg ggcctctgcctgcacaaagactatgtggctggccgggagttcatggcctggaaagatacg caccctgacgccttccccaaccagctcactcccatgcgggactgcctgtgcctggtggat gggggctttgccatcaactctccgttcccactcagcctgctgccccagagagcggtggac ctcattctgtcctttgactactccctggaggcccctttcgaggtcttacagatgacagag aagtactgcctggaccgaggcatccccttcccaagtatcgaggtgctccccgaggacttg gaggaaccccgtgagtgctacctgttcgccaaggccaaggacccccgctctcccatcgtg ctgcactttcccctcgtcaaccgtaccttctgcacacacctggccccaggtgtggagcga caaacagccgaggagaaggcctacggggactttgtggtcaatggggcagacactccatat ggcatgatgaacttcacctatgagcctgaggaatttgagcggctggtggctctgagtcga tacaatgttctgaacaatgtggagaccttgaggcatgcgctccggctggctctggagcga cggcaggctgggggcagggctggaggctga

DBGET integrated database retrieval system