Panthera leo (lion): 122222265
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Entry
122222265 CDS
T10741
Symbol
APEX1
Name
(RefSeq) DNA-(apurinic or apyrimidinic site) endonuclease
KO
K10771
AP endonuclease 1 [EC:
3.1.11.2
]
Organism
plez Panthera leo (lion)
Pathway
plez03410
Base excision repair
Brite
Enzymes [BR:
plez01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.11 Exodeoxyribonucleases producing 5'-phosphomonoesters
3.1.11.2 exodeoxyribonuclease III
122222265 (APEX1)
DNA repair and recombination proteins [BR:
plez03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
AP endonucleases
122222265 (APEX1)
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NCBI-GeneID:
122222265
NCBI-ProteinID:
XP_042798507
UniProt:
A0A8C9D331
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Position
B3:71152112..71154799
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AA seq
318 aa
AA seq
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MPKRGKKGAVAEDGEEPKIEPEAKKSKVGAKKNEKEAAGEGPVLYEDPPDQKTSPSGKSA
TLKICSWNVDGLRAWIKKKGLDWVKEEAPDILCLQETKCSENKLPAELQELPGLSHQYWS
APSDKEGYSGVGLLSRQCPLKVSYGIGEEEHDQEGRVIVAEFDSFVLVTAYVPNAGRGLV
RLEYRQRWDEAFRKFLKGLASRKPLVLCGDLNVAHEEIDLRNPKGNKKNAGFTPQERQGF
GELLEAVPLADSFRHLYPNTAYAYTFWTYMMNARSKNVGWRLDYFLLSHSLLPALCDSKI
RSKALGSDHCPITLYLAL
NT seq
957 nt
NT seq
+upstream
nt +downstream
nt
atgccgaagcgtgggaaaaagggagctgtggcagaagacggggaagagcccaagattgag
ccagaagccaagaagagtaaggttggagcaaagaaaaacgaaaaagaggcagcaggagag
gggccggtcctgtatgaggaccccccagatcagaaaacctcgcccagtggtaaatcggcc
acactcaagatctgctcctggaatgtggatgggcttcgagcctggattaaaaagaaaggt
ttagattgggtaaaggaagaagccccagatatcctgtgcctccaagagaccaaatgttca
gagaacaaactaccagctgaacttcaagagttgcctggactatcccatcaatactggtca
gctccttcagacaaggaagggtacagtggtgtgggcctgctctcccgccagtgcccactc
aaagtctcctatggcattggtgaggaggaacacgatcaggaaggccgggtgattgtggct
gaatttgactcatttgtgctggtaacagcctatgtacctaacgcaggccgaggtctggtc
cgcttggagtaccggcagcgctgggatgaggccttccgcaagttcctaaagggcttggct
tcccgcaagccccttgtgctctgtggggacctcaatgtggcccatgaagaaatcgacctt
cgcaaccccaagggaaacaaaaagaatgctggcttcactccacaagagcgtcaaggcttt
ggggaattactagaggctgtgcctctggctgacagcttccggcacctctaccccaacacg
gcctatgcatataccttttggacctacatgatgaatgctcgatccaaaaatgttggttgg
cgccttgattactttttgttgtcacactctctgttacccgcattgtgtgacagcaagatc
cgttccaaggccctgggcagtgaccactgtcccatcaccctgtacctagcactgtga
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