Panthera leo (lion): 122222371
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Entry
122222371 CDS
T10741
Symbol
PCK2
Name
(RefSeq) phosphoenolpyruvate carboxykinase [GTP], mitochondrial
KO
K01596
phosphoenolpyruvate carboxykinase (GTP) [EC:
4.1.1.32
]
Organism
plez Panthera leo (lion)
Pathway
plez00010
Glycolysis / Gluconeogenesis
plez00020
Citrate cycle (TCA cycle)
plez00620
Pyruvate metabolism
plez01100
Metabolic pathways
plez03320
PPAR signaling pathway
plez04068
FoxO signaling pathway
plez04151
PI3K-Akt signaling pathway
plez04152
AMPK signaling pathway
plez04910
Insulin signaling pathway
plez04920
Adipocytokine signaling pathway
plez04922
Glucagon signaling pathway
plez04931
Insulin resistance
plez04964
Proximal tubule bicarbonate reclamation
Module
plez_M00003
Gluconeogenesis, oxaloacetate => fructose-6P
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
122222371 (PCK2)
00020 Citrate cycle (TCA cycle)
122222371 (PCK2)
00620 Pyruvate metabolism
122222371 (PCK2)
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
122222371 (PCK2)
04151 PI3K-Akt signaling pathway
122222371 (PCK2)
04152 AMPK signaling pathway
122222371 (PCK2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
122222371 (PCK2)
04922 Glucagon signaling pathway
122222371 (PCK2)
04920 Adipocytokine signaling pathway
122222371 (PCK2)
03320 PPAR signaling pathway
122222371 (PCK2)
09155 Excretory system
04964 Proximal tubule bicarbonate reclamation
122222371 (PCK2)
09160 Human Diseases
09167 Endocrine and metabolic disease
04931 Insulin resistance
122222371 (PCK2)
Enzymes [BR:
plez01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.32 phosphoenolpyruvate carboxykinase (GTP)
122222371 (PCK2)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
PEPCK_GTP
PEPCK_N
Motif
Other DBs
NCBI-GeneID:
122222371
NCBI-ProteinID:
XP_042798734
UniProt:
A0A8C8XRM1
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All DBs
Position
B3:74083771..74094061
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AA seq
640 aa
AA seq
DB search
MAAVYRPGLRLSWPGLSPWGWSSWRSIQTLRVLSGDLSQLPAGVRDFVERSARLCQPEGI
HICDGTEAENTATLALLEKQGLIRKLPKYNNCWLARTDPKDVARVESKTVIVTPSQRDTV
PLPAGGARGQLGNWMSPAEFQQAVDERFPGCMQGRTMYVLPFSMGPVGSPLSRIGVQLTD
SAYVVASMRIMTRLGTPVLQALGDGNFVKCLHSVGQPLTGQGEPVSHWPCNPEKTLIGHV
PDQREIVSFGSGYGGNSLLGKKCFALRIASRLARDEGWLAEHMLILGITNPAGKKRYVAA
AFPSACGKTNLAMMRPALPGWKVECVGDDIAWMRFDSDGRLRAINPENGFFGVAPGTSAT
TNPNAMATIQSNTLFTNVAETSDGGVYWEGIDQPLPPGVTVTSWLGKPWKPGDKEPCAHP
NSRFCAPARQCPIMDPAWEAPEGVPIDAIIFGGRRPKGVPLVYEAFNWRHGVFVGSAMRS
ESTAAAEHKGKVIMHDPFAMRPFFGYNFGRYLEHWLSMEERKGARLPRIFHVNWFRRDEA
GHFLWPGFGENARVLDWICRRLEGEDSARETPIGLVPKEGALDLSGLGAIDTTQLFSLPK
DFWEQEVRDIRSYLTEQVNQDLPKEVLAELEALEGRVRRM
NT seq
1923 nt
NT seq
+upstream
nt +downstream
nt
atggctgctgtgtaccgccccggcctgcggcttagctggcctgggctgagcccctggggc
tggtcatcatggcgcagcatccagaccctacgagtactcagtggagatctgagccagctg
cccgctggagttcgagactttgtggagcgcagtgcccgcctgtgccaaccagagggcatc
cacatctgtgatggcaccgaggctgagaacactgccacattggccctactggaaaagcag
ggacttatccgaaagctccccaagtacaacaactgctggctggcccgcacagaccccaag
gatgtggcacgagtagagagcaagacagtgattgtaactccttctcaacgggacacagtg
cccctcccggctggtggggcccgtgggcagctaggcaactggatgtccccagctgagttc
cagcaagctgtggatgagaggtttccaggctgcatgcagggccgaaccatgtatgtgctt
ccattcagcatgggtcccgtgggctccccactgtcccgaatcggagtgcagctcactgat
tcggcctacgtggtggcaagcatgcgcatcatgacccggctggggacgcctgtgcttcag
gccctgggagatggcaactttgtcaagtgtctgcactctgtgggccagcccctgactggg
caaggggagccggtgagccattggccatgcaacccagagaaaaccctgattggccacgtg
cctgaccagagagagatcgtctccttcggcagcggctatggcggcaactccttgctgggc
aagaagtgctttgcccttcgcatcgcctctcggctggcccgggatgagggctggctggcg
gagcacatgctgatcctgggtatcaccaaccccgcagggaagaagcgctatgtggcagcc
gccttccccagcgcctgcggcaagactaacctggccatgatgcggccagcactgccaggc
tggaaagtggagtgtgtgggggatgacattgcctggatgaggtttgacagtgacggtcga
ctccgggccatcaaccctgagaatggcttcttcggcgtggcccctggcacctctgccacc
actaatcccaatgccatggccacaatccagagtaacactcttttcaccaatgtggctgag
accagtgatggtggagtgtactgggagggcattgaccagcctcttccacctggtgtcact
gtgacctcctggctgggaaaaccctggaaacctggagacaaggagccctgtgcacatccc
aactctcgcttttgtgccccggctcgccagtgccccatcatggacccagcctgggaggcc
cctgagggtgtccccattgatgccatcatctttggaggccgcagacccaaaggagtaccc
ttggtatatgaggccttcaactggcgccacggggtgtttgtaggcagtgctatgcgctct
gagtccactgctgcagctgaacacaaagggaaggtcatcatgcacgacccatttgccatg
cggcccttttttggctacaactttgggcgctacctagaacactggctgagcatggaggag
cgcaagggggcccggctaccccgcatcttccacgtcaactggttccggcgggatgaggcg
ggccacttcctgtggccaggctttggagagaatgctcgggtgctagactggatctgccgg
cggctagagggggaggacagtgcccgagagacgcccatcgggctggtgccaaaggaaggt
gccttggatctcagtggtctgggagccatagataccacacagctattctcactccccaag
gacttctgggaacaggaggtgcgtgacattcggagctacctgacagagcaagtcaatcag
gatctgcccaaggaggtgttggctgaactggaggccctggagggacgtgtgcgcagaatg
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