Panthera leo (lion): 122222555 Help Entry 122222555         CDS       T10741                                  Symbol PLA2G4D Name (RefSeq) cytosolic phospholipase A2 delta   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism plez  Panthera leo (lion) Pathway plez00564   Glycerophospholipid metabolism plez00565   Ether lipid metabolism plez00590   Arachidonic acid metabolism plez00591   Linoleic acid metabolism plez00592   alpha-Linolenic acid metabolism plez01100   Metabolic pathways plez04010   MAPK signaling pathway plez04014   Ras signaling pathway plez04072   Phospholipase D signaling pathway plez04217   Necroptosis plez04270   Vascular smooth muscle contraction plez04370   VEGF signaling pathway plez04611   Platelet activation plez04664   Fc epsilon RI signaling pathway plez04666   Fc gamma R-mediated phagocytosis plez04724   Glutamatergic synapse plez04726   Serotonergic synapse plez04730   Long-term depression plez04750   Inflammatory mediator regulation of TRP channels plez04912   GnRH signaling pathway plez04913   Ovarian steroidogenesis plez04921   Oxytocin signaling pathway plez05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:plez00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     122222555 (PLA2G4D)    00565 Ether lipid metabolism     122222555 (PLA2G4D)    00590 Arachidonic acid metabolism     122222555 (PLA2G4D)    00591 Linoleic acid metabolism     122222555 (PLA2G4D)    00592 alpha-Linolenic acid metabolism     122222555 (PLA2G4D)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     122222555 (PLA2G4D)    04014 Ras signaling pathway     122222555 (PLA2G4D)    04370 VEGF signaling pathway     122222555 (PLA2G4D)    04072 Phospholipase D signaling pathway     122222555 (PLA2G4D)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     122222555 (PLA2G4D)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     122222555 (PLA2G4D)    04664 Fc epsilon RI signaling pathway     122222555 (PLA2G4D)    04666 Fc gamma R-mediated phagocytosis     122222555 (PLA2G4D)   09152 Endocrine system    04912 GnRH signaling pathway     122222555 (PLA2G4D)    04913 Ovarian steroidogenesis     122222555 (PLA2G4D)    04921 Oxytocin signaling pathway     122222555 (PLA2G4D)   09153 Circulatory system    04270 Vascular smooth muscle contraction     122222555 (PLA2G4D)   09156 Nervous system    04724 Glutamatergic synapse     122222555 (PLA2G4D)    04726 Serotonergic synapse     122222555 (PLA2G4D)    04730 Long-term depression     122222555 (PLA2G4D)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     122222555 (PLA2G4D)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     122222555 (PLA2G4D) Enzymes [BR:plez01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      122222555 (PLA2G4D) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  cPLA2_C2 PLA2_B C2 STAT_linker YscJ_FliF Motif Other DBs NCBI-GeneID:  122222555 NCBI-ProteinID:  XP_042799059 LinkDB All DBs Position B3:60826330..60868493 Genome browser AA seq 803 aa AA seqDB search MVLKVEASACWRLTVKVLEARNLGWADLLSEADPYVTLQLPTAPGTKFKTKTITNSSHPV WNETFSFLIQSRVKNILELNVYDEDPVTEDDACFKILYDVSEVLPGQLLQKTFSLRPQGQ EELDVEFLMEKMSERPENLITNNVLVARELSCLDVHLVSIGSTATVTDQDELELVLKGSY EDTQTSALGTASFRFHYMAAQEAELSGHLKRLERNAWNSDKSAEHLTVPLRSLAMGKEVT INVPATNAPEVTLQLKTEGCPKELAMHLGFDLCAEEKAFLSRRKQVVAKALKQVLQLDRD LQEDEVPVVGIMATGGGARAMTSLYGHLLALQKLGLLDCVTYFSGISGSTWTMAHLYGDP EWSQGDLEGPIKCAREHLAKSKLEAFSPERLASYCRELELRAKQGHPKTFVDLWALVLES MLHGQVMDQKLSEQRAALERGQNPLPLYLSLNVKENHLETLDFKEWVEFSPYEVGFLKYG AFVPSDLFGSEFFMGRLMRKLPESRICFLEGIWSNVLSLNLLDAWYDLISSDDTWKQHVK DKIKNLEESPASMRTSSWLEASWLQPGTMLAKAFKGFLTGRPLHQHSLNFLRGLQLHQDY YSQRDFSTWADCELDSTPGQLTPQEPQLCLVDGGYFLNTSCPSMFRPGRRLDLILSFDYS LSSPFKTLQQTELYCRAQGLPFPRVDPNPQDQHQPTECHLFSDPTHPDTPVLLHFPLVNA SFKDHSAPGVLRSPTELPAGQVDLTGTASPYSLFNMTYKEEDFDRLLQLSDYNVRNSQDA ILQALRMAVKHRALGARPPTAQN NT seq 2412 nt NT seq  +upstreamnt  +downstreamnt atggttctcaaggtggaggcctctgcttgctggcggcttactgtgaaggtcctggaggcc aggaacctgggctgggctgacctgttgagtgaggcagacccctacgtgaccctacagctg cccactgcacctgggacaaagtttaaaaccaaaacaatcaccaactccagtcatcctgta tggaatgagaccttcagtttcctgatccagagtcgggtcaagaatattctggagctaaac gtctatgatgaggacccagtcacggaggatgatgcctgcttcaagattctctatgatgtc tcagaagtcctccctggccagctgctccagaagaccttctccctgcgtccccagggacag gaggagctggacgtggagttcctaatggaaaaaatgtcagaacgcccagaaaacctcatc accaacaacgtccttgtggcccgagagctgtcatgcctggatgtccatctggtcagcatt gggagcacagccacggtcacagatcaggatgagctggagttggtgctgaagggctcatat gaagacacacagacctctgcactaggcacagcatccttccgcttccattacatggcagcc caagaggcagaactgagtgggcatctgaagaggttggaaaggaatgcctggaattcagac aagtcagctgagcacctcactgtgcctctaaggtccttggccatgggaaaggaggtgacc attaatgttcctgctacaaacgccccagaagtgacactgcagctcaagactgagggctgc cctaaggagctggctatgcacctgggctttgatctgtgtgcagaggagaaagctttcctg agcaggaggaagcaggtggtggccaaggctctcaagcaggtcttgcagctggacagagac ctacaggaggatgaggtccctgttgtgggcataatggccacaggaggaggtgcccgggcc atgacgtctctctacggccacctgttggccctacagaagctgggcctcctggactgtgtg acctacttcagtggcatctcaggctctacatggacaatggcccacctctacggggacccg gagtggtcacagggggacctcgaaggacccatcaaatgtgctagagagcacctggccaag agcaaactggaggccttctccccagagcgcctagcaagctactgccgggagctggagctg cgggctaagcagggccaccccaagacctttgtggacctgtgggctcttgtgctggagtcc atgctgcatggccaggtgatggatcagaagctgtcagaacagagagctgcactggagcgg ggccagaaccctctgcccctctacttgagcctcaatgtcaaagagaaccatctggagacc ctggacttcaaggagtgggtagagttttcaccctatgaagtggggttcctgaagtatgga gcctttgtcccttctgatctctttggctctgagttcttcatggggcggctgatgaggaag ctccctgagtcccggatctgctttctggaaggtatctggagcaacgttttgtccctgaac ttgctggatgcctggtatgacctcatcagctctgatgacacctggaagcagcatgtcaag gacaaaattaagaacctggaggagtctcctgcctccatgaggacctcctcgtggctggag gcctcatggctgcaacccggaacaatgctggccaaggcatttaagggcttcctgacaggc aggccgctccaccagcatagcctcaacttccttcggggcctccagctgcaccaggactac tatagccagagagacttctccacctgggcagactgtgagctagactccacccctggccag cttacgcctcaggagccacagctctgcctggtagatggcggctacttcctcaacaccagc tgtccctccatgttccggccaggccgcagactggacctcatactctccttcgactactcc ctatcctcaccctttaagacgctgcagcagactgagctgtactgccgggcccagggactg ccattccctcgagtggaccccaaccctcaggaccaacaccagccaacagagtgccacctc ttctcggaccccactcaccctgatacccctgtcctgctgcacttcccactggtcaatgcc tccttcaaggaccactcagcccctggtgtcctacgcagccccacagaactcccagctggc caggtggatctcactgggaccgcctcaccctattccctattcaacatgacctacaaggag gaagattttgatcgcctgctgcagcttagtgactacaatgtacggaacagccaggatgcc attctgcaggccttgaggatggccgtgaaacaccgggccctgggggccagacctccaaca gcacagaattga

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