Panthera leo (lion): 122223860
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Entry
122223860 CDS
T10741
Symbol
DHTKD1
Name
(RefSeq) probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial isoform X1
KO
K15791
2-oxoadipate dehydrogenase E1 component [EC:1.2.4.-]
Organism
plez Panthera leo (lion)
Pathway
plez00310
Lysine degradation
plez00380
Tryptophan metabolism
plez00785
Lipoic acid metabolism
plez01100
Metabolic pathways
plez01210
2-Oxocarboxylic acid metabolism
Module
plez_M00032
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
122223860 (DHTKD1)
00380 Tryptophan metabolism
122223860 (DHTKD1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
122223860 (DHTKD1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03029 Mitochondrial biogenesis [BR:
plez03029
]
122223860 (DHTKD1)
Mitochondrial biogenesis [BR:
plez03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
122223860 (DHTKD1)
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Gene cluster
GFIT
Motif
Pfam:
OxoGdeHyase_C
Transket_pyr
E1_dh
Motif
Other DBs
NCBI-GeneID:
122223860
NCBI-ProteinID:
XP_042800801
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All DBs
Position
B4:10914453..10965295
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AA seq
938 aa
AA seq
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MATATVAAARRGFCRAPPLLFRRGYQTEKGVYGYRPRKPESREPRGGLARPSVDHGLARL
VTVYCEHGHKAAKINPLFTGQALPENVPEVQALVQTLQGPFNTTGLLNMGKEEASLEEIV
AYLNQIYCGQISIETSQLESQEEKDWFAKRFEELKKETFTTEERKHLSKLMLESQEFDHF
LATKFATVKRYGGEGAESMMGFFHELLKMAAYSGITDVIIGMPHRGRLNLLTGLLQFPPE
LMFRKMRGLSEFPEGVSATGDVLSHLTSSVDLDFGAHHPLHVTMLPNPSHLEAVNPVAVG
KTRGRQQSRQDGDYSPDSLAQPGDKVICLQVHGDASFCGQGIVPETFTLSNLPHFRIGGS
VHLIVNNQLGYTTPAERGRSSLYCSDIGKLVGCAVIHVNGDSPEEVVRATQLAFEYQRQF
RKDVIVDLLCYRQWGHNELDEPFFTNPVMYKIIRARKSIPDTYAEHLIANGLMTEEEVSD
IKTSYYAKLNDHLTNMAHYSPSATNLQAHWQGLVQPEASITTWNTGVPLDLLRFIGGKSV
EVPEGLHMHSHLLKMYVQSRLEKVMDGTKLDWATAEALALGSLLAEGFNVRLSGQDVGRG
TFSQRHAMVVCQNTDDTYIPLNHMDPNQKGFLEISNSPLSEEAVLGFEYGMSIESPRLLP
IWEAQFGDFFNGAQIIFDTFISGDGSVPASESSHSLSRAFPGEAKWLLQSGIVILLPHGY
DGAGPDHSSCRIERFLQMCDSVEEGVDGDTVNMFVVHPTTPAQYFHLLRRQMVRNFRKPL
IVASPKMLLRFPAAVSSLHEMAPGTTFKPVIGDSSVDPKNVKSLVFCCGKHFYALLKQRE
SLEAKKGDFAIIRLEELCPFPVDSLQQEMSKYKHVKDFIWSQEEPQNMGPWCFVSPRFEK
QLACKLRLVSRPPLPAPAVGIGALHLQQHEDVLTKTFA
NT seq
2817 nt
NT seq
+upstream
nt +downstream
nt
atggccacggccactgtggcagcagcaagacgaggcttctgccgagcccctccgctccta
ttccggcgcggctaccagacagagaagggtgtctatggctatcggccgaggaagcccgag
agccgggagccccggggcggcctggcgcgcccctcagttgatcatggccttgccagattg
gtgactgtatactgtgaacatggtcataaagctgccaaaatcaaccccctcttcactgga
caagccttgccggagaatgtgcctgaagtccaagctcttgtgcagaccctacagggacct
tttaataccacaggattgttgaacatggggaaggaggaggcctctcttgaggaaatagta
gcctatctcaaccaaatctactgtgggcaaatttctattgaaacctcccagcttgagagc
caggaggagaaagactggtttgccaaacggtttgaggaactgaaaaaagagacctttacc
acagaagagcgaaaacatctgtcaaaactaatgctagaatctcaggagtttgaccacttt
ttggccaccaagtttgctacagtgaagcggtatggaggcgaaggagctgaaagcatgatg
ggctttttccatgagttgctgaaaatggcagcctacagtgggataactgatgttattatt
ggcatgccccatagagggaggcttaatttattgacaggccttctgcaattccctccggag
ctgatgttccgtaaaatgcgaggcttaagtgaatttccagaaggtgtttcagccaccggt
gatgtcctatctcacttgacctcctcggttgacctggacttcggcgcgcaccatcccctc
catgtgacgatgctgccaaacccctcgcacctggaagctgtcaaccccgtggctgtcggg
aagactcggggaaggcagcagtctagacaggacggggactactctccagacagtttggct
cagcctggggacaaagtcatttgcttacaggttcacggtgatgcttctttctgtggtcag
gggattgttcctgaaacatttacgctgtctaatctcccacatttcagaattggtgggagt
gtccatctgattgtcaataaccagctgggttacaccactcctgctgaaagaggaaggtct
tccttatactgcagtgatatcgggaagcttgtgggctgtgccgtcatccatgtcaatgga
gacagcccagaagaagtggttcgggccacacaactggcttttgaataccagcgccagttc
cggaaggatgtgattgttgacttgttatgctacaggcagtggggccacaatgagctggat
gagcccttcttcacaaatccagtcatgtacaaaatcatcagagcccggaagagcatccca
gacacctatgcagagcaccttattgccaacggactcatgaccgaggaagaggtgtcggat
atcaaaacctcctactatgcaaagttaaatgaccatttaactaacatggcccactatagc
ccctcggccaccaacctgcaggctcactggcagggcctggtccagccggaggcttccatt
acaacctggaacactggtgtgcccctagacctcctgcgatttattggcgggaagtccgtg
gaggtgccggagggactccacatgcatagtcaccttctgaagatgtacgttcagtccaga
ctggagaaagtgatggatggaacaaaattagactgggctacggcagaagctcttgccttg
ggctcattacttgctgagggttttaatgtccgtctgagtgggcaagatgtcggccgtgga
acttttagtcagaggcacgccatggttgtttgccagaacactgatgacacctatatccct
ctgaaccatatggacccaaatcagaaagggtttctagagatcagcaacagcccgctgtca
gaagaggctgtcctgggatttgaatatgggatgagcatcgaaagccccaggttactgccc
atctgggaggctcagtttggcgatttcttcaatggtgctcagatcatctttgacacgttc
atctctggagatggttctgttcctgcttcggagagttctcactccctgtcacgtgctttc
ccaggggaggccaagtggctccttcagagcggcattgttatcctgcttccccacgggtat
gacggggctggacccgaccactcctcttgtcgcatagagcgtttcttgcagatgtgtgac
agtgtagaagagggggtggatggagacacagtgaacatgttcgtggtacacccaactact
cctgcacagtatttccacttgctcaggagacagatggtccggaatttccgaaaacccctc
attgttgcttctccgaagatgttactcaggttccctgcagccgtatcaagtcttcacgaa
atggcaccaggaacaacattcaagccggtcattggtgattcatctgtggatcccaaaaat
gttaagagtctagtgttctgctgtggcaaacatttctatgctctgctgaagcaaagagaa
tccttggaggccaagaagggtgactttgccatcatccgattagaagaactctgtcctttc
ccagtggattcgttacagcaagagatgagcaaatacaaacatgttaaagattttatttgg
agtcaggaggagcctcagaacatgggtccgtggtgctttgtttctcccaggtttgaaaag
caactggcctgcaagctccgtctcgtgagccgaccccctttgccagcacccgctgtagga
attggcgcccttcacctgcagcagcatgaagatgtcctcaccaagacctttgcttga
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