Panthera leo (lion): 122224477
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Entry
122224477 CDS
T10741
Symbol
PFKM
Name
(RefSeq) ATP-dependent 6-phosphofructokinase, muscle type isoform X1
KO
K00850
6-phosphofructokinase 1 [EC:
2.7.1.11
]
Organism
plez Panthera leo (lion)
Pathway
plez00010
Glycolysis / Gluconeogenesis
plez00030
Pentose phosphate pathway
plez00051
Fructose and mannose metabolism
plez00052
Galactose metabolism
plez01100
Metabolic pathways
plez01200
Carbon metabolism
plez01230
Biosynthesis of amino acids
plez03018
RNA degradation
plez04066
HIF-1 signaling pathway
plez04152
AMPK signaling pathway
plez04919
Thyroid hormone signaling pathway
plez04922
Glucagon signaling pathway
plez05230
Central carbon metabolism in cancer
Module
plez_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
122224477 (PFKM)
00030 Pentose phosphate pathway
122224477 (PFKM)
00051 Fructose and mannose metabolism
122224477 (PFKM)
00052 Galactose metabolism
122224477 (PFKM)
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03018 RNA degradation
122224477 (PFKM)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
122224477 (PFKM)
04152 AMPK signaling pathway
122224477 (PFKM)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
122224477 (PFKM)
04919 Thyroid hormone signaling pathway
122224477 (PFKM)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
122224477 (PFKM)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
plez01009
]
122224477 (PFKM)
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
plez03019
]
122224477 (PFKM)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.11 6-phosphofructokinase
122224477 (PFKM)
Protein phosphatases and associated proteins [BR:
plez01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
122224477 (PFKM)
Messenger RNA biogenesis [BR:
plez03019
]
Prokaryotic type
Bacterial mRNA degradation factors
RNA degradosome components
Other RNA degradosome components
122224477 (PFKM)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PFK
Motif
Other DBs
NCBI-GeneID:
122224477
NCBI-ProteinID:
XP_042802281
LinkDB
All DBs
Position
B4:74594972..74640248
Genome browser
AA seq
853 aa
AA seq
DB search
MHKEEFHLKFFTCVIQSRGLVRTPQSTGGEASTSSMLIQKPPPEIDNMKYLHATDDPDTV
EGIPILKTEWIMTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVF
FVHEGYQGLVDGGDNIREATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAHNLVKRG
ITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKAGKITAEEATKSSYLNIVGLVGSIDNDF
CGTDMTIGTDSALHRIIEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVF
IPECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDKTGKPITSEDIKNLVVKRLGY
DTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLM
ECVQMTKDVTKAMNDRKFDEAMKLRGRSFMNNWEVYKLLAHVRPPVSKGPSSIHTVAVMN
VGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKL
GTKRTLPKKSFEQISANITKFNIQGLVIIGGFEAYTGGLELMEGRKLFDELCIPFVVIPA
TVSNNVPGSDFSVGADTALNTICTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLA
AGADAAYIFEEPFTIRDLQANVEHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEE
GKGIFDSRKNVLGHMQQGGSPTPFDRNFATKMGAKAMNWMSGKIKESYRNGRIFANTPDS
GCVLGMRKRALVFQPVTELKEQTDFDHRIPKEQWWLKLRPILKILAKYEIDLDTSEHAHL
EHISRKRSGEASI
NT seq
2562 nt
NT seq
+upstream
nt +downstream
nt
atgcataaggaggaatttcatctgaaatttttcacgtgtgtgattcaatctcgcgggtta
gtcaggactcctcagagcacagggggagaagcttcaacttccagcatgctcatacaaaag
ccaccacctgagatagacaacatgaagtatctacatgctacggatgatccagacactgtg
gaaggcatacctattttgaaaactgagtggatcatgacccatgaagagcaccatgcagcc
aaaaccctggggattggcaaagccatcgccgtgttaacctctggtggagatgcccaaggt
atgaatgctgctgtcagggctgtggttcgagttggtatctttactggtgcccgtgtgttc
tttgtccatgagggttatcaaggcctggtggatggtggagataacatcagggaagccacc
tgggagagtgtttcgatgatgcttcagctgggaggcacagtcattggaagtgcccggtgc
aaggacttccgtgaacgagagggacgactccgtgctgcccacaacctggtgaagcgtggg
attactaatctgtgtgtcatcgggggtgatggcagcctcactggggctgacaccttccgt
tctgagtggagtgacttactgagtgacctccagaaagcgggtaagatcacagcggaggag
gctacgaagtccagctatctgaatatcgtgggtttggtgggctcaattgacaatgacttt
tgtggcactgatatgaccatcggcactgattccgccctgcaccggatcatagagattgtg
gacgccatcaccaccactgctcagagccaccagaggacgtttgtgctagaagtgatgggc
cggcactgtggatacctggcccttgtcacctctctctcctgtggggctgactgggttttt
attcctgagtgtccaccggatgatgactgggaggaacatctttgtcgccggctcagcgag
acaaggacccgtggttctcgtctcaacatcatcattgtggctgagggtgccatcgacaag
actgggaaacccataacctcagaagacatcaagaatctggtggtgaagcgtctgggatat
gacacccgggtcactgtcttggggcatgtgcagcggggtgggacaccatcagcctttgac
cggatcctgggcagcaggatgggtgtggaggcagtgatggcacttttggaagggactcca
gacaccccagcctgtgtggtgagcctctctgggaaccaggctgtgcgcctgcccctcatg
gagtgtgtccaaatgaccaaagatgtgaccaaggccatgaacgacaggaaatttgatgaa
gccatgaagctgagaggccggagcttcatgaacaactgggaagtgtacaagcttctggct
catgtcagacccccagtctctaagggaccgagtagcatacacacagtggccgtgatgaac
gtgggggccccagccgcaggcatgaacgctgccgtccgttccaccgtgaggattggcctc
atccagggcaaccgggtgctggttgtacatgatggcttcgagggcctggccaagggtcag
atcgaggaagctggctggagctatgttgggggctggactggccaaggtggttccaaactt
gggactaaaaggactctacccaagaagagctttgagcagatcagtgccaacatcactaag
tttaacattcagggccttgtcatcattgggggctttgaggcttacacagggggcctggaa
ctgatggagggcaggaagctgtttgacgagctgtgcatcccgtttgtggtcatccccgcg
acggtctccaacaacgtccccggctcggacttcagcgtgggggctgacacagcactcaat
actatctgcacgacctgtgaccgcatcaagcagtcagcggcaggcaccaagcgtcgggtg
tttatcatcgaaacgatgggtggctactgtggctacctggccaccatggcaggactggca
gctggggccgatgctgcctacatttttgaggagcccttcaccattcgggacctgcaggca
aatgttgaacatctggtgcagaagatgaaaaccactgtgaaaaggggcttggtgttaagg
aatgagaagtgcaatgagaactataccacggacttcatcttcaacctgtactctgaggag
gggaagggcatatttgacagcaggaagaatgtgcttgggcacatgcagcagggtggaagc
ccaactccgtttgacaggaattttgccactaagatgggtgccaaggctatgaactggatg
tctgggaaaatcaaagagagttaccgtaatgggaggatcttcgccaatacaccagactca
ggctgtgttctggggatgcgtaagagggctctggtctttcaaccggtgactgagctgaag
gagcagacggattttgaccaccgcatccccaaggagcagtggtggctgaagctgaggccc
atcctcaaaatcctagccaagtatgagattgacttggacacctcagagcacgcccacctg
gagcacatcagccggaagcgatctggagaagcttctatctaa
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