Panthera leo (lion): 122224782
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Entry
122224782 CDS
T10741
Symbol
TBK1
Name
(RefSeq) serine/threonine-protein kinase TBK1
KO
K05410
TANK-binding kinase 1 [EC:
2.7.11.10
]
Organism
plez Panthera leo (lion)
Pathway
plez04014
Ras signaling pathway
plez04137
Mitophagy - animal
plez04140
Autophagy - animal
plez04620
Toll-like receptor signaling pathway
plez04621
NOD-like receptor signaling pathway
plez04622
RIG-I-like receptor signaling pathway
plez04623
Cytosolic DNA-sensing pathway
plez04657
IL-17 signaling pathway
plez04936
Alcoholic liver disease
plez05014
Amyotrophic lateral sclerosis
plez05022
Pathways of neurodegeneration - multiple diseases
plez05135
Yersinia infection
plez05160
Hepatitis C
plez05161
Hepatitis B
plez05162
Measles
plez05163
Human cytomegalovirus infection
plez05164
Influenza A
plez05165
Human papillomavirus infection
plez05167
Kaposi sarcoma-associated herpesvirus infection
plez05168
Herpes simplex virus 1 infection
plez05169
Epstein-Barr virus infection
plez05170
Human immunodeficiency virus 1 infection
plez05171
Coronavirus disease - COVID-19
plez05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
122224782 (TBK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
122224782 (TBK1)
04137 Mitophagy - animal
122224782 (TBK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
122224782 (TBK1)
04621 NOD-like receptor signaling pathway
122224782 (TBK1)
04622 RIG-I-like receptor signaling pathway
122224782 (TBK1)
04623 Cytosolic DNA-sensing pathway
122224782 (TBK1)
04657 IL-17 signaling pathway
122224782 (TBK1)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
122224782 (TBK1)
05161 Hepatitis B
122224782 (TBK1)
05160 Hepatitis C
122224782 (TBK1)
05171 Coronavirus disease - COVID-19
122224782 (TBK1)
05164 Influenza A
122224782 (TBK1)
05162 Measles
122224782 (TBK1)
05168 Herpes simplex virus 1 infection
122224782 (TBK1)
05163 Human cytomegalovirus infection
122224782 (TBK1)
05167 Kaposi sarcoma-associated herpesvirus infection
122224782 (TBK1)
05169 Epstein-Barr virus infection
122224782 (TBK1)
05165 Human papillomavirus infection
122224782 (TBK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
122224782 (TBK1)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
122224782 (TBK1)
05022 Pathways of neurodegeneration - multiple diseases
122224782 (TBK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
122224782 (TBK1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
122224782 (TBK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plez01001
]
122224782 (TBK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
plez04131
]
122224782 (TBK1)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
122224782 (TBK1)
Protein kinases [BR:
plez01001
]
Serine/threonine kinases: Other
IKK family [OT]
122224782 (TBK1)
Membrane trafficking [BR:
plez04131
]
Autophagy
Xenophagy
Other xenophagy associated proteins
122224782 (TBK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
Pkinase_fungal
ABC1
Kinase-like
DUF713
CEP63
KIF21A
COG6_N
Motif
Other DBs
NCBI-GeneID:
122224782
NCBI-ProteinID:
XP_042803003
LinkDB
All DBs
Position
B4:89333674..89383724
Genome browser
AA seq
729 aa
AA seq
DB search
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEETTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPISCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQQMTAHKIYIHSYNTATVFHELVYKQTKIISSNQELIYEGRRLV
IEPGRLAQHFPKTTEENPIFVVSREPLSTIGLIYEKISLPKVHPRYDLDGDASMAKAITG
VVCYACKIANTLLLYQELMRKGIRWLIELVKDDYNETVHKKTEVVITLDFCIRNIEKTVK
VYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIESRLSPGGLLADMWAHQE
GTHPKDRHVEKLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FTDECVKKYEAFLDKSEEWMRKMLHLRKQLLSLTNQCFDIEEEVSKYQDYTNELQETLPQ
KMFSASSGIKHTMTPIYPCSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMD
GGLRNVDCL
NT seq
2190 nt
NT seq
+upstream
nt +downstream
nt
atgcagagcacctctaatcatctgtggcttttatctgatattttaggccaaggagctact
gcaaatgtctttcgtggaaggcataagaaaactggtgacttatttgctatcaaagtattt
aataacataagcttccttcgtccagtggatgttcaaatgagagaatttgaagtgttaaaa
aaactcaatcacaaaaatattgtcaaattatttgctattgaagaggagacaacaacaaga
cataaagtacttattatggaattttgtccatgcggaagtttatacactgttttagaagag
ccatctaatgcctatggactaccagagtctgaatttttaattgttttgcgagatgtggtg
ggtggaatgaaccatctacgagagaatggcatagtgcaccgtgatatcaagccaggaaac
atcatgcgtgttataggggaagatggacagtctgtgtacaaactcacagattttggtgca
gctagagaattagaagatgatgaacagtttgtttctttgtatggcacagaagaatatttg
catcctgatatgtatgagagagcagtgctaagaaaagatcatcagaagaaatacggagca
acagttgatctttggagcattggggtaacgttttaccatgcagctactggatcactgccg
ttcagaccatttgaagggccacgtaggaataaggaagtgatgtataaaataattactgga
aagccttctggtgcaatatctggagtacagaaagcagaaaatggaccaatcgactggagt
ggagacatgcctatttcttgcagtctttctcggggccttcaagttctacttacccctgtt
cttgcaaacatccttgaggcagatcaggaaaagtgttggggttttgaccagttttttgca
gaaactagtgatatacttcatcggatgataattcatgttttttcactgcaacaaatgaca
gctcataagatttatattcatagctacaatactgctactgtatttcatgaactggtatat
aaacaaaccaaaattatttcttcaaatcaagaacttatatatgaaggacgacgtttagtt
atagaacctggaagactggcacagcattttcctaaaactaccgaggaaaatcccatcttt
gtagtgagtcgggaacctctgagtaccataggattgatatacgagaaaatttcccttcct
aaagtacatccacgttacgatttagatggggatgctagcatggctaaggcaataacagga
gttgtatgttatgcttgtaaaattgccaataccttgctgctttatcaggaattaatgcga
aaggggatacgatggttgatagaattagttaaagatgattataatgaaactgttcacaaa
aagacagaagttgtgatcacactggatttctgcatcagaaacattgaaaaaactgtgaaa
gtatacgaaaagttgatgaagatcaacctagaagcagcagagttaggtgaaatttcagac
atacacaccaaattgttgagactttccagttctcagggaacaatagaaaccagtcttcag
gatatcgaaagcagattatctccaggtggattgttggcagacatgtgggcccatcaagaa
ggcactcatccaaaagatagacatgtagaaaagctacaagtcctgctaaattgcatcaca
gagatttactatcagttcaaaaaagacaaagcagaacgtagactagcttataatgaagaa
cagatccacaaatttgataagcaaaaactgtattaccatgcaacaaaagctatgacccat
tttacagacgaatgtgttaaaaaatatgaggcatttttggataagtcagaagaatggatg
agaaagatgcttcatcttaggaaacagttattatcactaactaatcagtgctttgatatt
gaagaagaagtgtcaaagtatcaagattatacaaatgagttacaagaaactttgcctcaa
aaaatgttttcagcctccagtggaatcaaacataccatgaccccaatttatccttgttct
aatacattagtggaaatgactcttggtatgaagaaattaaaggaagagatggaaggagtg
gttaaagaacttgccgaaaataatcatattttagaaaggtttggctctttaaccatggat
ggcggccttcgcaatgttgactgtctttag
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