KEGG   Panthera leo (lion): 122224896
Entry
122224896         CDS       T10741                                 
Symbol
DUSP6
Name
(RefSeq) dual specificity protein phosphatase 6
  KO
K21946  dual specificity phosphatase 6 [EC:3.1.3.16 3.1.3.48]
Organism
plez  Panthera leo (lion)
Pathway
plez04010  MAPK signaling pathway
plez05202  Transcriptional misregulation in cancer
plez05221  Acute myeloid leukemia
Brite
KEGG Orthology (KO) [BR:plez00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122224896 (DUSP6)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    122224896 (DUSP6)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    122224896 (DUSP6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:plez01009]
    122224896 (DUSP6)
Enzymes [BR:plez01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     122224896 (DUSP6)
    3.1.3.48  protein-tyrosine-phosphatase
     122224896 (DUSP6)
Protein phosphatases and associated proteins [BR:plez01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   MAPK phosphatases
    122224896 (DUSP6)
SSDB
Motif
Pfam: DSPc Rhodanese Tc-R-P PTP-SAK Y_phosphatase Init_tRNA_PT PTPlike_phytase
Other DBs
NCBI-GeneID: 122224896
NCBI-ProteinID: XP_042803270
UniProt: A0A8C8WN26
LinkDB
Position
B4:complement(110947818..110952354)
AA seq 381 aa
MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG
IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLK
KLKDEGCRAFYLEGGFSKFQAEFALHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRAPTQ
QLYFTTPSNQNVYQAGSLQST
NT seq 1146 nt   +upstreamnt  +downstreamnt
atgatagatacgctcagacccgtgcccttcgcgtcggaaatggcgatcagcaagaccgtg
gcgtggctcaacgagcagttggagctgggcaacgagcggctgctgctgatggactgccgg
ccgcaggagctgtatgagtcgtcgcacatcgagtcagccatcaacgtggccatcccgggc
atcatgctgcggcgcctgcaaaagggcaacctgccggtgcgcgcgctcttcacccgtggc
gaggaccgggaccgcttcacccggcgctgcggcaccgacaccgtggtgctttacgacgag
agtagcagcgactggaacgagaacaccggcggcgagtcggtgcttggattgctgctcaag
aagctcaaggacgagggctgccgggcgttctacttggaaggtggcttcagtaagttccaa
gccgagttcgccctgcactgcgagacgaatctagacggctcatgtagcagcagctcgcca
ccgttgccagtgctggggctcgggggcctgcggatcagctctgactcctcctcggacatt
gagtctgaccttgaccgagaccccaatagtgcaacggactcggatggcagcccgctgtcc
aacagccagccttctttccccgtggagatcttgcccttcctctatttgggctgtgccaag
gactccaccaacctggacgtgttggaggagttcggcatcaagtacatcttgaacgtcacc
cccaatttgccgaatctctttgagaacgcaggagagtttaaatacaagcagatccccatc
tcggatcactggagtcaaaacctgtcccagtttttccctgaggccatttctttcatagat
gaagcccggggcaaaaactgtggcgtcttggtgcattgcctggctggcatcagccgttcg
gtcactgtaactgtggcttatcttatgcagaagctcaatctgtcaatgaacgatgcttat
gacattgtcaagatgaagaaatccaacatctcgcccaacttcaacttcatgggccagctg
ctggacttcgagaggacgcttggactcagcagcccctgtgacaatcgggcccccacgcag
cagctctattttaccaccccctccaaccagaacgtctaccaggcgggctccctgcaatcc
acgtga

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