KEGG   Panthera leo (lion): 122225095
Entry
122225095         CDS       T10741                                 
Symbol
RAC2
Name
(RefSeq) ras-related C3 botulinum toxin substrate 2 isoform X1
  KO
K07860  Ras-related C3 botulinum toxin substrate 2
Organism
plez  Panthera leo (lion)
Pathway
plez04010  MAPK signaling pathway
plez04014  Ras signaling pathway
plez04015  Rap1 signaling pathway
plez04024  cAMP signaling pathway
plez04062  Chemokine signaling pathway
plez04071  Sphingolipid signaling pathway
plez04310  Wnt signaling pathway
plez04360  Axon guidance
plez04370  VEGF signaling pathway
plez04510  Focal adhesion
plez04520  Adherens junction
plez04613  Neutrophil extracellular trap formation
plez04650  Natural killer cell mediated cytotoxicity
plez04662  B cell receptor signaling pathway
plez04664  Fc epsilon RI signaling pathway
plez04666  Fc gamma R-mediated phagocytosis
plez04670  Leukocyte transendothelial migration
plez04810  Regulation of actin cytoskeleton
plez05020  Prion disease
plez05135  Yersinia infection
plez05163  Human cytomegalovirus infection
plez05170  Human immunodeficiency virus 1 infection
plez05200  Pathways in cancer
plez05210  Colorectal cancer
plez05212  Pancreatic cancer
plez05231  Choline metabolism in cancer
plez05415  Diabetic cardiomyopathy
plez05416  Viral myocarditis
plez05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:plez00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    122225095 (RAC2)
   04014 Ras signaling pathway
    122225095 (RAC2)
   04015 Rap1 signaling pathway
    122225095 (RAC2)
   04310 Wnt signaling pathway
    122225095 (RAC2)
   04370 VEGF signaling pathway
    122225095 (RAC2)
   04071 Sphingolipid signaling pathway
    122225095 (RAC2)
   04024 cAMP signaling pathway
    122225095 (RAC2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    122225095 (RAC2)
   04520 Adherens junction
    122225095 (RAC2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    122225095 (RAC2)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    122225095 (RAC2)
   04650 Natural killer cell mediated cytotoxicity
    122225095 (RAC2)
   04662 B cell receptor signaling pathway
    122225095 (RAC2)
   04664 Fc epsilon RI signaling pathway
    122225095 (RAC2)
   04666 Fc gamma R-mediated phagocytosis
    122225095 (RAC2)
   04670 Leukocyte transendothelial migration
    122225095 (RAC2)
   04062 Chemokine signaling pathway
    122225095 (RAC2)
  09158 Development and regeneration
   04360 Axon guidance
    122225095 (RAC2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122225095 (RAC2)
   05231 Choline metabolism in cancer
    122225095 (RAC2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    122225095 (RAC2)
   05212 Pancreatic cancer
    122225095 (RAC2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    122225095 (RAC2)
   05163 Human cytomegalovirus infection
    122225095 (RAC2)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    122225095 (RAC2)
  09164 Neurodegenerative disease
   05020 Prion disease
    122225095 (RAC2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    122225095 (RAC2)
   05415 Diabetic cardiomyopathy
    122225095 (RAC2)
   05416 Viral myocarditis
    122225095 (RAC2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:plez04031]
    122225095 (RAC2)
GTP-binding proteins [BR:plez04031]
 Small (monomeric) G-proteins
  Rho Family
   Rac/Cdc42 [OT]
    122225095 (RAC2)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU
Other DBs
NCBI-GeneID: 122225095
NCBI-ProteinID: XP_042803658
UniProt: A0A8C8WII8
LinkDB
Position
B4:complement(130503678..130519208)
AA seq 192 aa
MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAG
QEDYDRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLR
DDKDTIERLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQ
PTRPQKRPCSIL
NT seq 579 nt   +upstreamnt  +downstreamnt
atgcaggccatcaagtgcgtggtggtgggagatggagccgtgggcaagacctgccttctt
atcagctataccaccaacgccttccctggagagtacatccccaccgtgttcgacaactat
tcagccaatgtgatggtggacagcaagcccgtgaacctggggctgtgggacaccgcgggg
caggaggactatgaccgcctccggccgctctcctacccacagacggacgtctttctcatc
tgcttctcccttgtgagccctgcctcctatgagaatgtccgtgccaagtggttccctgag
gtgcggcaccactgccccagcacgcccatcatcctggtgggcaccaagctggatctgcgg
gacgacaaggacaccatcgagaggctgaaggagaagaagctggcgcctattacctacccg
cagggcctggcactggccaaggagatcgactcggtcaaatacctggagtgttcagccctc
acccagcgaggcctgaaaaccgtcttcgatgaggcgatccgggccgtcctgtgcccccag
cccacccggccacagaagcgcccctgcagcatcctttag

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