Panthera leo (lion): 122225260
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Entry
122225260 CDS
T10741
Symbol
PPARA
Name
(RefSeq) peroxisome proliferator-activated receptor alpha isoform X1
KO
K07294
peroxisome proliferator-activated receptor alpha
Organism
plez Panthera leo (lion)
Pathway
plez03320
PPAR signaling pathway
plez04024
cAMP signaling pathway
plez04920
Adipocytokine signaling pathway
plez04922
Glucagon signaling pathway
plez04931
Insulin resistance
plez04932
Non-alcoholic fatty liver disease
plez04936
Alcoholic liver disease
plez05160
Hepatitis C
plez05207
Chemical carcinogenesis - receptor activation
plez05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
122225260 (PPARA)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
122225260 (PPARA)
04920 Adipocytokine signaling pathway
122225260 (PPARA)
03320 PPAR signaling pathway
122225260 (PPARA)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
122225260 (PPARA)
09172 Infectious disease: viral
05160 Hepatitis C
122225260 (PPARA)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
122225260 (PPARA)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
122225260 (PPARA)
04932 Non-alcoholic fatty liver disease
122225260 (PPARA)
04931 Insulin resistance
122225260 (PPARA)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
plez03000
]
122225260 (PPARA)
09183 Protein families: signaling and cellular processes
03310 Nuclear receptors [BR:
plez03310
]
122225260 (PPARA)
Transcription factors [BR:
plez03000
]
Eukaryotic type
Zinc finger
Cys4 thyroid hormone receptor-like
122225260 (PPARA)
Nuclear receptors [BR:
plez03310
]
1. Thyroid hormone like
1C. Peroxisome proliferator-activated receptor (PPAR)
122225260 (PPARA)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
zf-C4
Hormone_recep
Motif
Other DBs
NCBI-GeneID:
122225260
NCBI-ProteinID:
XP_042804052
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All DBs
Position
B4:137759303..137826088
Genome browser
AA seq
505 aa
AA seq
DB search
MELGPHQKRAAGLPGTRVAWAGPSSASELRFRNHLSKMVDTESPICPLSPLEADDLESPL
SEEFLQEMGNIQEISQSIGEDSSGSFSFTEYQYLGSGPGSDGSVITDTLSPASSPSSVTC
PVAPGSADEPSSVALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLAYDKCDRSC
KIQKKNRNKCQYCRFHKCLSAGMSHNAIRFGRMPRSEKAKLKAEILTCEHDPEDAETADL
KSLAKRIYEAYLKNFNMNKVKARVILAGKANNNPPFVIHDMETLCMAEKTLVAKLVANGI
QNKEAEVRIFHCCQCTSVETVTELTEFAKSIPGFANLDLNDQVTLLKYGVYEAIFAMLSS
VMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAII
CCGDRPGLLNVGHIEKMQEGIVHVLKLHLQSNHPDNIFLFPKLLQKMADLRQLVTEHAQL
VQVIKKTESDAALHPLLQEIYRDMY
NT seq
1518 nt
NT seq
+upstream
nt +downstream
nt
atggaattagggccccatcagaagcgagccgcggggctgccgggaaccagagttgcctgg
gctggaccctcctcggcttcagagttgcgtttccggaaccatctaagcaagatggtggac
acagaaagcccgatttgccccctctcccccctcgaggctgatgatctggaaagcccatta
tctgaagaattcctacaagaaatgggaaacatccaagagatttctcaatccattggggag
gacagttccggaagctttagctttacagagtaccagtatttaggaagtggcccaggatca
gacggatctgttattacagacaccctctcaccggcttcgagtccctcgtcggtcacttgt
cccgtggctccaggcagtgctgatgaaccttccagcgtagccctgaacattgaatgtaga
atctgtggggacaaagcctcgggctaccattacggagttcacgcctgtgaaggctgcaag
ggcttcttccggaggacgatccgactaaagctggcgtatgacaaatgtgaccgtagctgc
aagatccagaaaaagaatcgaaataagtgccagtactgtcgtttccacaagtgcctttcg
gctgggatgtcccataacgcaattcgttttggacggatgccaaggtctgaaaaagcaaaa
ctgaaagcggaaattctcacatgtgaacacgacccagaagatgctgaaacggcggatctg
aaatccctcgccaagagaatttacgaggcctacctcaagaacttcaacatgaacaaggtc
aaggcccgggtcatcctggcggggaaagccaacaacaacccgccctttgtcatacatgac
atggagacactgtgcatggccgagaagactctggtggccaagttggtggccaacggcatc
cagaacaaggaagcagaagtccgcatcttccactgctgccagtgcacgtctgtggagacg
gtcacggagctcacggagttcgccaagtccatccctggctttgcaaacttggacttgaac
gaccaagtcactttgctgaaatatggagtgtatgaggccatatttgcgatgctgtcttct
gtgatgaataaagacgggatgctggtagcatatggaaatggttttataactcgtgaattc
ctaaagagcctaaggaaaccattttgtgatatcatggagcctaagtttgactttgcgatg
aagttcaacgcgttggaactggacgacagtgatatttcccttttcgtggctgctataatt
tgctgtggagatcggccgggccttctcaacgtgggacacattgaaaaaatgcaggagggc
atcgtgcacgtgctcaaacttcacctgcagagcaaccacccagacaacatcttcctcttc
ccaaagctcctgcaaaaaatggcagacctccggcagctggtcaccgagcacgcgcagctc
gtgcaggtcatcaagaagaccgagtctgatgccgccctgcacccgctgctgcaggaaatc
taccgggacatgtactga
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