Panthera leo (lion): 122226147
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Entry
122226147 CDS
T10741
Symbol
ACVR1
Name
(RefSeq) activin receptor type-1
KO
K04675
activin receptor type-1 [EC:
2.7.11.30
]
Organism
plez Panthera leo (lion)
Pathway
plez04060
Cytokine-cytokine receptor interaction
plez04081
Hormone signaling
plez04350
TGF-beta signaling pathway
plez04550
Signaling pathways regulating pluripotency of stem cells
plez05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
122226147 (ACVR1)
09133 Signaling molecules and interaction
04081 Hormone signaling
122226147 (ACVR1)
04060 Cytokine-cytokine receptor interaction
122226147 (ACVR1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
122226147 (ACVR1)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
122226147 (ACVR1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plez01001
]
122226147 (ACVR1)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
122226147 (ACVR1)
Protein kinases [BR:
plez01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR1 family [OT]
122226147 (ACVR1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
TGF_beta_GS
Activin_recp
Pkinase_fungal
Haspin_kinase
FTA2
CD59
APH
Motif
Other DBs
NCBI-GeneID:
122226147
NCBI-ProteinID:
XP_042804780
UniProt:
A0A8C8Y1U8
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Position
C1:complement(146547876..146693236)
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AA seq
509 aa
AA seq
DB search
MVDGVMILPVLMMIAFPSPSMEDEKPKVNPKLYMCVCEGLSCGNEDHCEGQQCFSSLSIN
DGFHVYQKGCFQVYEQGKMTCKTPPSPGQAVECCQGDWCNRNITAQLPTKGKSFPGTQNF
HLEVGLIILSVVFAVCLLACLLGVALRKFKRRNQERLNPRDVEYGTIEGLITTNVGDSTL
ADLLDHSCTSGSGSGLPFLVQRTVARQITLLECVGKGRYGEVWRGSWQGENVAVKIFSSR
DEKSWFRETELYNTVMLRHENILGFIASDMTSRHSSTQLWLITHYHEMGSLYDYLQLTTL
DTVSCLRIVLSIASGLAHLHIEIFGTQGKPAIAHRDLKSKNILVKKNGQCCIADLGLAVM
HSQSTNQLDVGNNPRVGTKRYMAPEVLDETIQVDCFDSYKRVDIWAFGLVLWEVARRMVS
NGIVEDYKPPFYDVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTLTSLAKLMKECWYQ
NPSARLTALRIKKTLTKIDNSLDKLKTDC
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atggtagatggagtgatgattcttcctgtgctaatgatgattgctttcccttcccctagt
atggaagatgagaagcccaaggtaaaccccaaactttacatgtgtgtgtgtgaaggcctc
tcctgtgggaacgaagaccactgtgaaggccagcagtgcttttcctcactgagcataaat
gatggcttccatgtctaccagaaaggctgtttccaggtctacgagcaagggaagatgacc
tgtaagaccccgccatcacctggccaagctgtggagtgttgccaaggcgactggtgtaac
aggaacatcacggcccagctgcccaccaaagggaaatcctttcctggaacacagaatttc
cacttggaggtcggcctcattattctgtctgtagtgtttgcagtatgccttctagcttgc
ctactgggagtcgctctccgaaaatttaaaaggcgcaatcaagaacgcctcaatcccaga
gatgtggagtacggcaccatcgaagggctcatcaccaccaatgttggagacagcacttta
gcagatttattggatcattcatgtacatcaggaagcggctctggcctcccttttctggta
caaagaacggtggctcgtcagatcacactgttggagtgtgtcgggaagggccggtatggt
gaggtgtggaggggcagttggcagggggagaacgtcgctgtgaagatcttctcctcccgg
gatgagaagtcatggttcagggaaacagaattgtacaacactgtgatgctgaggcatgaa
aatattttaggttttattgcttcagacatgacatcaagacactccagtacccagttatgg
ttaattacacattatcacgaaatgggatcgttgtatgactatcttcagcttactactctg
gatacagttagctgcctgcgaatagtgctgtctatagctagtggtctcgcacatttgcac
atagagatatttgggacccaagggaaaccagccatagctcatcgagatttaaagagcaaa
aacatcctggttaagaagaatggacagtgttgcatagcagatttgggcctggcagtcatg
cattcccagagtaccaatcagctcgatgtggggaacaacccccgtgtgggcaccaaacgc
tacatggcccctgaagttctagatgaaaccattcaggtggattgttttgattcttacaag
agagttgatatttgggcctttggacttgtcttgtgggaggtggccagacgtatggtgagc
aatggtattgtggaggattacaagccaccattttatgatgtggttcccaatgacccaagt
tttgaagatatgagaaaggtggtctgtgtggatcaacagaggccaaacatacccaataga
tggttctcagacccgacattaacctctctggccaagctgatgaaggaatgctggtatcag
aacccatccgcgagactcacagctctgcggatcaaaaagactttgaccaaaattgataat
tccctagacaaattgaaaacggactgttga
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