Panthera leo (lion): 122226334
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Entry
122226334 CDS
T10741
Symbol
PDE1A
Name
(RefSeq) calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X1
KO
K13755
calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:
3.1.4.17
]
Organism
plez Panthera leo (lion)
Pathway
plez00230
Purine metabolism
plez01100
Metabolic pathways
plez04020
Calcium signaling pathway
plez04740
Olfactory transduction
plez04742
Taste transduction
plez04924
Renin secretion
plez05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
122226334 (PDE1A)
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
122226334 (PDE1A)
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
122226334 (PDE1A)
09157 Sensory system
04740 Olfactory transduction
122226334 (PDE1A)
04742 Taste transduction
122226334 (PDE1A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
122226334 (PDE1A)
Enzymes [BR:
plez01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
122226334 (PDE1A)
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Motif
Pfam:
PDEase_I
PDEase_I_N
Motif
Other DBs
NCBI-GeneID:
122226334
NCBI-ProteinID:
XP_042805251
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Position
C1:complement(168937515..169266960)
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AA seq
579 aa
AA seq
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MILRAARFSTRAASRSFSQVLLRFMRNIIMGSTATEIEELENTPLKYLIGEHTEKMWQRL
KGILRCLVKQLEKGDVNVVDLKKNIEYAASVLEAVYIDETRQMIHGRPIPGPGSQRLLDT
DDELSDIQTDSVPLEVRDWLASTFTRKMGMMKKKSEEKPKFRSIVHAVQAGIFVERMYRK
SYHMVGLAYPEAVIITLKDVDKWSFDVFALNEASGEHSLKFMIYELFTRYDLINRFKIPV
SCLICFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGIMHWLTELEILAMVFAAA
IHDYEHTGTTNNFHIQTRSDVALLYNDRSVLENHHVSAAYRLMQEEEMNVLINLSKDDWR
DLRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPEGIDKAKTMSLILHAADISHPAKSWQLH
HRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMVAQSQIGFIDFIVEPTFSLLTDSTE
KIITPLIEEASKTETPSYGASSVDLFRRSNMKGTMNDGTYSPDYSLASVDLKSFKNNLVD
IIQQNKERWKELAAQGEPDLHKNSEDLVNAEEKHADTHS
NT seq
1740 nt
NT seq
+upstream
nt +downstream
nt
atgatactgagggcagccaggttttcaacgcgagccgccagcagaagcttctcccaggtc
ctcttgagatttatgaggaatatcatcatggggtctactgctacagaaattgaagaattg
gaaaacacccctcttaagtatctgataggagaacacactgaaaaaatgtggcaacgcctg
aaaggaatactaagatgcttagtgaagcagctggaaaaaggtgatgttaacgtcgtagac
ttaaagaagaacattgaatatgcagcatctgtgttggaagctgtttatattgatgaaaca
agacaaatgattcatggaagaccaattccaggcccagggtcacaaagactgctggatacc
gatgatgaactcagtgacattcagactgattcagtcccattggaagtacgggactggttg
gcttctacttttacacggaaaatggggatgatgaaaaagaaatctgaggaaaagccaaaa
tttcgaagcatcgtgcatgctgttcaagctgggatttttgtggaaaggatgtacagaaag
tcctatcacatggttggtttggcatatccagaagctgtcataataacattaaaggatgtt
gataaatggtcttttgatgtatttgccttaaatgaagcaagtggagagcacagcctgaag
tttatgatttatgaactgtttaccagatatgatcttatcaatcgtttcaagattcctgtt
tcttgcctaatttgctttgcagaagctttagaagttggttacagcaagtacaaaaatcct
tatcacaatttgattcatgcagctgatgtcactcaaactgtgcattacataatgcttcat
acaggtatcatgcactggctcactgaactggaaattttagcaatggtctttgctgctgcc
attcatgattatgagcatacaggaaccacaaacaactttcacattcagaccaggtcagat
gttgcccttttatataatgatcgctcagtccttgagaatcaccatgtgagtgcagcttat
cggcttatgcaagaagaagaaatgaatgttttgataaatttatccaaagatgactggagg
gatcttcggaacctagtgattgaaatggttttgtctacagacatgtcaggtcacttccag
caaattaaaaatataagaaacagtttgcagcagcctgaagggattgacaaagccaaaacg
atgtccctgattctccatgcagcagacatcagccacccagccaaatcctggcagctgcac
caccggtggaccatggccctgatggaggagtttttcctacagggagataaagaagctgag
ttaggacttccattttccccactttgtgaccggaagtcaacgatggtggcccagtcacaa
ataggtttcattgacttcatagtagagccaacattttctcttctgacagattcaacagag
aaaattattactcctcttatagaggaagcctcaaaaacagaaactccttcctatggggca
agcagtgttgatttgtttagacgatcaaatatgaagggcaccatgaacgatggaacctat
tccccagactactcccttgcaagcgtggacctgaaaagcttcaaaaacaacctggtggac
atcatccagcagaacaaagagaggtggaaagagttagctgcacaaggtgaacctgatctt
cataagaactcagaagacctagtaaatgctgaggaaaaacatgctgatacacactcatag
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