Panthera leo (lion): 122226403
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Entry
122226403 CDS
T10741
Symbol
GLS
Name
(RefSeq) glutaminase kidney isoform, mitochondrial isoform X1
KO
K01425
glutaminase [EC:
3.5.1.2
]
Organism
plez Panthera leo (lion)
Pathway
plez00220
Arginine biosynthesis
plez00250
Alanine, aspartate and glutamate metabolism
plez00470
D-Amino acid metabolism
plez01100
Metabolic pathways
plez04724
Glutamatergic synapse
plez04727
GABAergic synapse
plez04964
Proximal tubule bicarbonate reclamation
plez05206
MicroRNAs in cancer
plez05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
122226403 (GLS)
00220 Arginine biosynthesis
122226403 (GLS)
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
122226403 (GLS)
09150 Organismal Systems
09155 Excretory system
04964 Proximal tubule bicarbonate reclamation
122226403 (GLS)
09156 Nervous system
04724 Glutamatergic synapse
122226403 (GLS)
04727 GABAergic synapse
122226403 (GLS)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
122226403 (GLS)
05230 Central carbon metabolism in cancer
122226403 (GLS)
Enzymes [BR:
plez01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.1 In linear amides
3.5.1.2 glutaminase
122226403 (GLS)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Glutaminase
EF-hand_14
Ank_4
Ank_2
Ank
Ank_3
Ank_5
Ank_KRIT1
Motif
Other DBs
NCBI-GeneID:
122226403
NCBI-ProteinID:
XP_042805418
UniProt:
A0A8C8XW40
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All DBs
Position
C1:176723951..176809492
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AA seq
672 aa
AA seq
DB search
MMRLRGSAMLRDLFLRPPAASCAALRRAQPLVTLCRRPRGGGQGAAGPAAAARLYPWWGG
GGRPAGPLARGLSSSPSEILQELGKGGTQQQQQQSGASPPAAPSAPSPKDGPGETDAFGN
SEGKELVASGENKIKQGLLPSLEDLLFYTIAEGQEKIPVHKFITALKSTGLRTSDPRLKE
CMDMLRLTLQTTSDGVMLDKDLFKKCVQSNIVLLTQAFRRKFVIPDFMSFTSHIDELFES
AKKQSGGKVADYIPQLAKFSPDLWGVSVCTVDGQRHSIGDTKVPFCLQSCVKPLKYAIAV
NDLGTEYVHRYVGKEPSGLRFNKLFLNEDDKPHNPMVNAGAIVVTSLIKQGVNNAEKFDY
VMQFLNKMAGNEYVGFSNATFQSERESGDRNFAIGYYLKEKKCFPEGTDMVGILDFYFQL
CSIEVTCESASVMAATLANGGFCPITGERVLSPEAVRNTLSLMHSCGMYDFSGQFAFHVG
LPAKSGVAGGILLVVPNVMGMMCWSPPLDKMGNSVKGIHFCHDLVSLCNFHNYDNLRHFA
KKLDPRREGGDQRVKSVINLLFAAYTGDVSALRRFALSAMDMEQRDYDSRTALHVAAAEG
HVEVVKFLLEACKVNPFPKDRWNNTPMDEALHFGHHDVFKILQEYQVQYTPQGDSDNGKE
NQTVHKNLDGLL
NT seq
2019 nt
NT seq
+upstream
nt +downstream
nt
atgatgcgactgcgaggctcggcgatgctgcgggacctgttcctgcggcctcccgccgct
tcctgcgcagctctgaggcgggcacagcccctcgtcacactgtgccggcgtccccgaggc
gggggacagggggccgcgggcccagcggccgccgcgcggctttacccgtggtggggcggg
ggcggccggccggcggggcccctcgcgcggggactgtctagctccccttcggagatcctg
caggagctgggcaaggggggcacgcagcagcagcagcagcagtctggggcgtcgccgccc
gcggccccatcggctcccagccccaaggacggccccggggagacggatgcgttcggcaac
agtgagggcaaggagctggtggcctcgggcgaaaataaaataaaacagggtctgttacct
agcttggaagatttgctgttctatacaattgcagaaggacaagagaaaatacctgttcat
aaatttattacagcactcaaatctacaggattgcgaacgtctgatcccaggttgaaagag
tgtatggatatgttaagattaactcttcaaacaacatcagatggtgtcatgctagacaaa
gatctttttaaaaaatgtgttcaaagcaacattgttttgttgacacaagcctttagaaga
aagtttgtcattcctgactttatgtcttttacctctcacattgatgagttatttgaaagt
gctaaaaagcagtctggaggaaaggttgcggattatattcctcagctagccaagttcagt
cctgatttgtggggtgtgtctgtgtgtaccgtagatggacagaggcattctattggagat
accaaagttccattttgtcttcagtcctgtgtaaaacctttgaaatatgcaattgctgtt
aatgaccttggaacagaatatgtgcatcgatatgttgggaaagagccaagtggattaaga
ttcaacaaactgtttttaaatgaagatgataagccacacaatcctatggtaaatgctgga
gcaattgttgtgacttcattaataaagcaaggagtgaataatgctgaaaaatttgactat
gtgatgcagtttttgaataagatggctggcaatgaatacgttggattcagtaatgcaacg
tttcagtctgaaagagaaagtggagatcgaaattttgcaataggatattacctaaaagaa
aaaaagtgttttccagaaggcacagacatggttggtatattagacttctatttccagcta
tgctccattgaagtaacatgtgaatcagccagtgtgatggctgcaacactggctaatggt
ggtttctgtccaattactggtgagagagtactgagccctgaagcagttcgaaatacactg
agtttgatgcattcctgtggcatgtatgatttctccgggcagtttgctttccatgttggt
cttcctgcaaaatctggagttgctgggggcattcttttagttgtccctaatgtcatgggc
atgatgtgctggtctcctcctctggacaagatgggcaacagtgttaagggaattcacttc
tgtcatgatcttgtttctctctgtaatttccataactatgataatttgagacactttgca
aaaaaacttgatcctcgaagagaaggtggtgatcaaagggtgaagtcagtgataaacctt
ttgttcgctgcgtatactggagatgtatctgcacttcgaagatttgctctatcagccatg
gacatggaacagcgagactatgactctagaacagcactccatgtagctgctgcagagggt
catgttgaagttgttaaatttttgctggaggcatgcaaagtaaatcctttccccaaggac
aggtggaataacactcccatggatgaagcgttgcacttcggacaccacgatgtatttaag
atcctccaggaataccaagtgcagtacacgcctcaaggagattccgacaacggaaaagaa
aatcaaacggtccataagaatttggatggattgttataa
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