KEGG   Panthera leo (lion): 122226406
Entry
122226406         CDS       T10741                                 
Symbol
STAT1
Name
(RefSeq) signal transducer and activator of transcription 1-alpha/beta
  KO
K11220  signal transducer and activator of transcription 1
Organism
plez  Panthera leo (lion)
Pathway
plez04062  Chemokine signaling pathway
plez04217  Necroptosis
plez04380  Osteoclast differentiation
plez04620  Toll-like receptor signaling pathway
plez04621  NOD-like receptor signaling pathway
plez04625  C-type lectin receptor signaling pathway
plez04630  JAK-STAT signaling pathway
plez04658  Th1 and Th2 cell differentiation
plez04659  Th17 cell differentiation
plez04917  Prolactin signaling pathway
plez04919  Thyroid hormone signaling pathway
plez04933  AGE-RAGE signaling pathway in diabetic complications
plez04935  Growth hormone synthesis, secretion and action
plez05140  Leishmaniasis
plez05145  Toxoplasmosis
plez05152  Tuberculosis
plez05160  Hepatitis C
plez05161  Hepatitis B
plez05162  Measles
plez05164  Influenza A
plez05165  Human papillomavirus infection
plez05167  Kaposi sarcoma-associated herpesvirus infection
plez05168  Herpes simplex virus 1 infection
plez05169  Epstein-Barr virus infection
plez05171  Coronavirus disease
plez05200  Pathways in cancer
plez05212  Pancreatic cancer
plez05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
plez05321  Inflammatory bowel disease
Brite
KEGG Orthology (KO) [BR:plez00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    122226406 (STAT1)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    122226406 (STAT1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    122226406 (STAT1)
   04621 NOD-like receptor signaling pathway
    122226406 (STAT1)
   04625 C-type lectin receptor signaling pathway
    122226406 (STAT1)
   04658 Th1 and Th2 cell differentiation
    122226406 (STAT1)
   04659 Th17 cell differentiation
    122226406 (STAT1)
   04062 Chemokine signaling pathway
    122226406 (STAT1)
  09152 Endocrine system
   04917 Prolactin signaling pathway
    122226406 (STAT1)
   04935 Growth hormone synthesis, secretion and action
    122226406 (STAT1)
   04919 Thyroid hormone signaling pathway
    122226406 (STAT1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    122226406 (STAT1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    122226406 (STAT1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    122226406 (STAT1)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    122226406 (STAT1)
  09172 Infectious disease: viral
   05161 Hepatitis B
    122226406 (STAT1)
   05160 Hepatitis C
    122226406 (STAT1)
   05171 Coronavirus disease
    122226406 (STAT1)
   05164 Influenza A
    122226406 (STAT1)
   05162 Measles
    122226406 (STAT1)
   05168 Herpes simplex virus 1 infection
    122226406 (STAT1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    122226406 (STAT1)
   05169 Epstein-Barr virus infection
    122226406 (STAT1)
   05165 Human papillomavirus infection
    122226406 (STAT1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    122226406 (STAT1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    122226406 (STAT1)
   05140 Leishmaniasis
    122226406 (STAT1)
  09163 Immune disease
   05321 Inflammatory bowel disease
    122226406 (STAT1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    122226406 (STAT1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:plez03000]
    122226406 (STAT1)
Transcription factors [BR:plez03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   STAT
    122226406 (STAT1)
SSDB
Motif
Pfam: STAT_alpha STAT_bind STAT_int STAT_linker STAT1_TAZ2bind SH2 DUF1633
Other DBs
NCBI-GeneID: 122226406
NCBI-ProteinID: XP_042805437
UniProt: A0A8C8XVG1
LinkDB
Position
C1:complement(176811803..176853382)
AA seq 750 aa
MSQWYELQQLDSKFLEQVHQLYDDSFPMEIRQYLAQWLEKQDWEHAANDVSFATIRFHDL
LSQLDDQYSRFSLENNFLLQHNIRKSKRNLQDNFQEDPIQMSMIIYNCLKEERKILENAQ
RFNQAQSGNIQSTVMLDKQKELDSKVRNVKDKVMCIEHEIKTLEDLQDEYDFKCKTLQNR
EHETNGVAKNDQKQEQMLIKKMYLMLDSKRKEVVHKIIELLNITELTQKALINDELVEWK
QRQQSACIGGPPNACLDQLQNWFTIVAESLQQVRQQLKKLEELEQKYTYEHDPITKNKQG
LWDRTFNLFQQLIQSSFVVERQPCMPTHPQRPLVLKTGVQFTVKLRLLVKLQELNYNLKV
KVLFDKDVNERNTVKGFRKFNILGTHTKVMNMEESTNGSLAAEFRHLQLKEQKNAGTRTN
EGPLIVTEELHSLSFETQLCQPGLVIDLETTSLPIVVISNVSQLPSGWASILWYNMLVTE
PRNLSFFLNPPCARWSQLSEVLSWQFSSVTKRGLNVDQLNMLGEKLLGPNAGPDGLIPWT
RFCKENINDKNFPFWLWIESILELIKKHLLSLWNDGCIVGFISKERERALLKDQQPGTFL
LRFSESCREGAITFTWVERSQNGGEPYFHAVEPYTKKELSAVTFPDIIRNYKVMAAENIP
ENPLKYLYPNIDKDHAFGKYYSRPKEAPEPMELDGPKGTGYIKTELISVSEVHPSRLQTT
DNLLPMSPEEFDEVSRIVGPVEFDTMMNAV
NT seq 2253 nt   +upstreamnt  +downstreamnt
atgtctcagtggtatgagcttcaacagcttgactccaaattcctggaacaggttcaccag
ctctatgatgacagttttcccatggaaatcagacagtacctagcacagtggctagaaaag
caagactgggagcatgctgctaatgatgtttcatttgccaccatccgttttcatgacctc
ctatcacagctggatgatcaatacagtcgcttttctttggaaaataattttttgttgcag
cataacataaggaaaagcaagcgtaatcttcaggataattttcaggaagacccaatacag
atgtctatgattatctataactgtctgaaggaagaaaggaagatcctggaaaatgcccag
agattcaatcaggcgcagtcggggaatattcagagcactgtgatgttagacaaacagaag
gagcttgacagtaaagtcagaaatgtgaaggataaagttatgtgtatagagcatgaaatc
aagacattagaagacttacaagatgaatatgactttaaatgcaagaccttgcagaacaga
gaacatgaaaccaatggtgtggcaaaaaatgatcagaaacaagaacagatgttaatcaag
aagatgtatttaatgcttgacagtaagagaaaggaagtagttcacaaaataatagagttg
ttgaacatcaccgaacttacccagaaagccctgattaatgatgaactggtggagtggaag
cagagacagcagagtgcctgtattgggggaccccccaacgcttgtcttgatcagctgcaa
aactggttcaccatagttgccgagagtctgcagcaggttcgtcagcagcttaaaaagctt
gaggaattggaacagaaatacacctatgaacacgaccctatcacaaaaaacaaacaaggg
ctgtgggaccgcaccttcaacctgttccaacagctcattcagagctcatttgtggtggaa
agacagccttgcatgccaactcatcctcagaggccactagtcttgaagactggggtccag
ttcaccgtgaagttgagactgttggtgaaattgcaggagctgaattataatttgaaagtc
aaagtcttatttgataaagatgtgaacgagagaaatacagtaaaaggatttagaaaattc
aacattttgggcacacatacaaaagtgatgaacatggaggaatccaccaacggaagtctg
gccgccgaatttcgacacctgcaactgaaagaacagaaaaatgctggcaccagaactaat
gagggccccctcatcgttacagaagagcttcactcccttagttttgaaacccagttgtgc
cagcctggtttggtcattgacctcgagacgacctctctgcccatcgtggtgatctccaat
gtcagccagctcccgagtggctgggcctccatcctgtggtacaacatgctggtgacagaa
cccaggaatctgtccttcttcctgaacccgccctgtgcacgatggtctcagctttcagag
gtgctgagttggcagttttcttctgtcaccaaaagaggtctcaatgtggaccagctgaac
atgctgggagagaagctacttggtcctaatgctggccccgatggtctcattccgtggacg
aggttctgtaaggaaaatataaatgacaaaaattttcctttctggctttggattgaaagc
atccttgaactcattaaaaaacacctgctctctctctggaatgatgggtgtatcgtgggc
tttatcagcaaggagcgagagcgtgccctgctgaaggatcagcagccagggacgttcctg
ctgcggttcagtgagagctgccgggaaggggccatcacgttcacgtgggtggagcggtcc
cagaacggaggggaaccttacttccacgcagtggaaccctacacgaagaaagaactttct
gctgttactttccctgatattattcgcaattacaaagtcatggctgctgaaaatattcca
gagaatcccctgaagtatctgtatccaaatattgataaggaccatgcctttgggaaatac
tactccaggccaaaggaagctccagaaccaatggaacttgatggccctaaaggaactgga
tacatcaagactgaattgatttctgtgtctgaagttcatccttctcgacttcagaccaca
gacaatcttctccccatgtctcctgaggagtttgacgaggtgtctcggatagtgggtcct
gtagaattcgacactatgatgaatgcagtatag

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