Panthera leo (lion): 122226644
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Entry
122226644 CDS
T10741
Symbol
PLCD4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1
KO
K05857
phosphatidylinositol phospholipase C, delta [EC:
3.1.4.11
]
Organism
plez Panthera leo (lion)
Pathway
plez00562
Inositol phosphate metabolism
plez01100
Metabolic pathways
plez04020
Calcium signaling pathway
plez04070
Phosphatidylinositol signaling system
plez04919
Thyroid hormone signaling pathway
plez04933
AGE-RAGE signaling pathway in diabetic complications
Module
plez_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
122226644 (PLCD4)
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
122226644 (PLCD4)
04070 Phosphatidylinositol signaling system
122226644 (PLCD4)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
122226644 (PLCD4)
09160 Human Diseases
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
122226644 (PLCD4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
plez04131
]
122226644 (PLCD4)
Enzymes [BR:
plez01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
122226644 (PLCD4)
Membrane trafficking [BR:
plez04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
122226644 (PLCD4)
Endocytosis
Macropinocytosis
Phospholipase C
122226644 (PLCD4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
EF-hand_like
EF-hand_10
C2
EF-hand_7
PH
EF-hand_1
EF-hand_6
EF-hand_5
PH_12
EF-hand_PLCG2
GDPD
EF-hand_15
Wap1
Pes-10
Motif
Other DBs
NCBI-GeneID:
122226644
NCBI-ProteinID:
XP_042806099
LinkDB
All DBs
Position
C1:201540934..201565530
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AA seq
826 aa
AA seq
DB search
MVSLMQGRLPINQDVLLMQKGMLARKVRSKSWKKLRYFRLQDDGMTVWHARQAGGKAKPS
FSISDVETVREGHESELLRSLAEEFPLEQGFTIVFHGRRSNLDLVANSVEEAQIWMQGLQ
HLVDFVTSMDQKERLDQWLSDWFQRGDKNQDGRMSFPEVQRLLHLMNVEMDQEYALQLFQ
AADTSQSGTLEGEEFVEFYKALTKRPEVQEVFENFSADGQKLTLLEFVDFLREEQKEGER
ASDLALELIDRYEPSDSGKVRHVLSLDGFLSYLCSKDGDVFNPACLPIYQDMTQPLNHYY
INSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDIWDGPSGEPIVYHGHTLTSRIPF
KDVVATVAQYAFQTSDYPVILSLENHCTWEQQQVMALHLTEILGEQLLSTTLDGLLPTQL
PSPEELRRKILVKGKKLQTLEEDLEEEEEEEVLESQLEGEQEAKPELEAQFESEPQELSP
RSKDKKKDKVVMCPPFCTPICCQIMVQAPSSKHESLLFPKQKCKPIMCPSLSALVVYLKA
VSFHSFTHSREHYRFYETSSFSETKAKSLIKEAGNAFVQHNAWQLSRVYPSGLRTDSSNY
NPQELWNAGCQMVAMNVQTAGLEMDICDGLFRQNGGCGYVLKPDFLRDTQSSFHPERPIS
PFKAQTLLIQVISGQQLPKEDMTKERSIVDPLVRVEIFGVRPDTTRQETNYVENNGFNPY
WGQTLCFQVLVPELALLRFVVNDYNWKTRHDFIGQYTLPWTCMQQGGPVPQALASGPAPA
PFLMLSSCPFPGYRHIHLLSKDGTSLHPASIFVHICIREGLEGDES
NT seq
2481 nt
NT seq
+upstream
nt +downstream
nt
atggtgtccttgatgcaaggccggctgcccatcaatcaagatgtgctgctgatgcagaaa
ggcatgctggcgcgcaaggtgaggtccaaaagctggaagaaactaagatacttcagactt
caggatgatggcatgacagtctggcatgcccggcaggcgggaggcaaggccaagcccagc
ttctcaatctctgatgtggagacagtgcgtgagggccatgagtctgagctgttgcgcagc
ctggcagaggagttccccctggagcagggcttcaccatcgtcttccatggccgccgttcc
aacctggacctggtggccaacagcgttgaggaggcccagatatggatgcaggggctccag
catttggtggactttgtcaccagcatggaccaaaaggagcggctggaccagtggctgagt
gactggttccagcgtggagacaagaaccaggatggtcgcatgagtttcccagaggtccag
cggttactacacctgatgaatgtggaaatggaccaggaatatgccttgcagcttttccaa
gcagcagacacatcccagtctgggactctggaaggagaagaatttgtagagttctataag
gcgttgactaagcgccctgaggtgcaggaagtgtttgaaaacttttcagctgatgggcag
aagctgaccctgttggaatttgtggatttcctccgagaggagcagaaagaaggagaaaga
gcttcagatcttgctctggaactcatcgaccgctatgagccttcagatagcggcaaagtg
cgacatgtgctgagcttggatggcttcctcagctacctctgctcgaaggatggcgatgtc
ttcaacccagcctgcctccccatctaccaggatatgactcaacccctgaaccactattat
atcaactcctctcacaacacctacctagtgggggaccagctttgtggccagagcagcgtc
gaaggatatatacgggccctgaagagggggtgccgctgtgtggaggtggatatatgggac
ggacctagtggggagcctatcgtttaccatggacacaccctgacctcccgcatcccgttc
aaagatgtcgtggccactgtagcacagtacgccttccagacatcagactacccagtcatc
ttgtccctggagaaccactgcacgtgggagcagcagcaggtcatggcgcttcatctgact
gagatcttgggggagcaattgctgagcacaaccttggacgggctgctgcccactcaactg
ccctcgcctgaggaacttaggaggaagatcctggtgaaggggaagaagctacagaccctt
gaggaggaccttgaggaagaggaagaggaggaagtgctggagtctcaactggagggagag
caggaggctaagccagagctggaggcccagtttgagtctgagccccaggagctgagcccc
cgcagtaaggacaaaaagaaggacaaggttgtgatgtgtccgccgttttgtacgcctatc
tgttgtcagattatggttcaggctcctagttccaagcatgagtcccttctctttcccaag
cagaaatgcaaacccatcatgtgtccatccctctctgccctggttgtctacttgaaggcc
gtctcattccacagcttcactcactcgagggagcactaccgcttctatgagacatcatct
ttctctgaaaccaaggccaagagcctcatcaaagaggctggcaatgcgtttgtgcagcac
aacgcctggcagttaagccgtgtgtatcccagtggcctgaggacagattcgtccaactac
aacccccaggaactctggaatgcgggttgccagatggtggctatgaatgtgcagactgcg
gggctggagatggacatctgtgatgggctcttccgccagaacggtggctgtggctatgtg
ctgaagccagacttcctgcgtgacacccagagttccttccacccagagaggcccatcagc
cctttcaaagcccagaccctcctaatccaggtgatcagtggtcagcaactccccaaggag
gacatgactaaagagaggtccattgtggatccactggtgagagttgaaatcttcggtgtc
cgcccagacacaacccggcaagagacgaactatgtggagaacaatggttttaatccatac
tgggggcagacactatgcttccaggtcctggtgcctgaactggccctgctgcgttttgtg
gtaaatgattacaactggaaaacccgacacgactttattgggcagtacacacttccttgg
acctgcatgcaacaaggtgggccggtcccccaagccctggccagcggtccagctccggct
cccttcctaatgctgtcctcctgcccctttccaggctaccgccacatacacctactctcc
aaggacggcaccagcctccatccagcctccatctttgtgcatatctgcatccgggaagga
ctagagggggatgaatcctaa
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