Panthera leo (lion): 122227491
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Entry
122227491 CDS
T10741
Symbol
PDE4B
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
plez Panthera leo (lion)
Pathway
plez00230
Purine metabolism
plez01100
Metabolic pathways
plez04024
cAMP signaling pathway
plez04928
Parathyroid hormone synthesis, secretion and action
plez05032
Morphine addiction
Brite
Enzymes [BR:
plez01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
122227491 (PDE4B)
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NCBI-GeneID:
122227491
NCBI-ProteinID:
XP_042807976
UniProt:
A0A8C8WTA9
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Position
C1:54049410..54485118
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AA seq
737 aa
AA seq
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MKKSRSVMAVTADDNVKDYLECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQS
ERARTPEGDGISRPTTLPLTTLPSIAITTVSQEGFDVENGPSPGRSPLDPQASSSSGLVL
HATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVR
NNFTVLTNLHGASNKRSPAAASQPPVSRVNLQEESYQKLAMETLEELDWCLDQLETIQTY
RSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKK
KKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYS
HNRPLTCIMYAIFQERDLLKTFKISSDTFVTYMMTLEDHYHSDVAYHNSLHAADVAQSTH
VLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHH
LAVGFKLLQEEHCDIFQNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVT
SSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGME
ISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQS
PSPPLDEQNRDCQGLMEKFQFELTLEEEDSEGPEKEGEGHDYFSSTKTLCVIDPEHRDSL
GGTDVDIVTEDKSPIDT
NT seq
2214 nt
NT seq
+upstream
nt +downstream
nt
atgaagaaaagcaggagtgtgatggcagtgacggctgatgataatgtgaaagattatctt
gaatgtagcttgagtaaatcctacagttcttctagtaacacacttgggatcgacctctgg
agagggagaaggtgttgctcaggaaacttacagttaccgcccctgtcccaaagacagagt
gagagggcaaggactcccgagggagatggcatttccagacctaccacgctccctttgacg
acactcccaagcatcgctattacaaccgtaagccaggagggctttgatgtggaaaatggc
ccttccccaggtcggagcccactggacccccaggccagctcttcctctgggttggtgctc
catgccacctttcccgggcacagccagcggagagagtcctttctctaccgatcagatagc
gactatgatttgtcaccgaaggcgatgtcaagaaactcttcacttccaagcgagcaacat
ggcgatgacttgattgtaacaccttttgcccaggtccttgccagcttgcgaagtgtgaga
aacaattttactgtactgacaaaccttcatggagcatccaacaagaggtccccagctgct
gctagtcagccacctgtctccagagtaaacctgcaagaagaatcttatcaaaaattagca
atggaaacgctggaggaattggactggtgcttagaccagctagagaccatccagacctac
cgctctgtcagtgagatggcttctaacaagttcaagagaatgctgaaccgggagctgaca
cacctctcagagatgagccgatcagggaaccaggtttctgaatacatttcaaatactttc
ttagacaagcagaatgatgtggagattccatcacctacccagaaggacagagagaaaaag
aaaaagcaacagctcatgacgcagataagcggagtgaaaaaactgatgcacagttcaagc
ttaaacaatacaagcatctcacgctttggagtcaacacagaaaatgaagatcatctggcc
aaggagctggaagatctgaacaaatggggccttaacatcttcaatgtggctggatattca
cacaataggcccctcacatgcatcatgtatgccatattccaggaaagagacctcctaaag
acattcaaaatctcatctgatacatttgtaacctacatgatgactttagaagaccattac
cattctgatgtggcgtatcataacagcctacatgctgctgatgtagcccagtcaacccat
gttcttctttctacgccagcattagatgctgtcttcacagatttggaaattctggccgcc
atttttgcagctgctatccatgatgttgatcaccctggagtctccaaccagtttctcatc
aacacaaattcagaacttgctttgatgtataatgatgaatctgtgttggaaaaccatcac
cttgccgtgggtttcaaactgctgcaagaagaacactgtgatatcttccagaatctcacc
aagaagcaacgccagacactcaggaaaatggttatcgacatggtgttagcaactgatatg
tccaaacatatgagcctgctggcagacctgaaaacaatggtggaaacaaagaaagttaca
agttcaggtgttcttctcctggacaactacacggatcgtatacaggtccttcgcaacatg
gtacactgtgcagacctaagcaaccccaccaagtccttggaattatatcggcagtggaca
gaccgcatcatggaggagttcttccagcagggagacaaagagcgggagaggggaatggag
atcagcccaatgtgtgataagcacacagcttctgtggaaaaatcccaggttggtttcatt
gactacattgtccatccactctgggagacgtgggcagatctggtgcagcctgatgcccag
gacattctggatacgttagaagataatagaaactggtatcagagcatgataccgcagagt
ccctccccaccactggacgagcagaacagagactgtcagggtctgatggagaagtttcag
tttgaactgacccttgaagaggaggattccgaaggccctgaaaaagagggagagggtcac
gactatttcagcagcacaaagacactttgcgtgatcgatcctgaacatagggattcacta
ggagggactgatgtagacattgtgacagaagacaagtcccccatcgacacataa
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