Panthera leo (lion): 122227867
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Entry
122227867 CDS
T10741
Symbol
GAD1
Name
(RefSeq) glutamate decarboxylase 1 isoform X1
KO
K01580
glutamate decarboxylase [EC:
4.1.1.15
]
Organism
plez Panthera leo (lion)
Pathway
plez00250
Alanine, aspartate and glutamate metabolism
plez00410
beta-Alanine metabolism
plez00430
Taurine and hypotaurine metabolism
plez00650
Butanoate metabolism
plez01100
Metabolic pathways
plez04727
GABAergic synapse
plez04940
Type I diabetes mellitus
Module
plez_M00027
GABA (gamma-Aminobutyrate) shunt
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
122227867 (GAD1)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
122227867 (GAD1)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
122227867 (GAD1)
00430 Taurine and hypotaurine metabolism
122227867 (GAD1)
09150 Organismal Systems
09156 Nervous system
04727 GABAergic synapse
122227867 (GAD1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04940 Type I diabetes mellitus
122227867 (GAD1)
Enzymes [BR:
plez01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.15 glutamate decarboxylase
122227867 (GAD1)
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GFIT
Motif
Pfam:
Pyridoxal_deC
Aminotran_5
Beta_elim_lyase
DegT_DnrJ_EryC1
SepSecS
OKR_DC_1
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
122227867
NCBI-ProteinID:
XP_042808523
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All DBs
Position
C1:158630117..158668933
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AA seq
594 aa
AA seq
DB search
MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK
SRLVSAFKERQSSKNLLSCENSDRDGRFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEV
VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV
RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWS
SKDGDGIFSPGGAISNMYSIMAARYKFFPEVKTKGMAAVPKLVLFTSEHSHYSIKKAGAA
LGFGTDNVILIKCNERGKIIPADLEAKILEAKQKGYVPLYVNATAGTTVYGAFDPIQEIA
DICEKYNLWLHVDAAWGGGLLMSRKHRHKLSGIERANSVTWNPHKMMGVLLQCSAILVKE
KGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQI
NKCLELAEYLYAKIKNREEFEMVFDGEPEHTNVCFWYIPQSLRGIPDSPERREKLHRVAP
KIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL
NT seq
1785 nt
NT seq
+upstream
nt +downstream
nt
atggcgtcttcgaccccttcttcgtccgcaacctcctcgaatgcgggagcggaccccaat
actaccaacctgcgccccacaacatatgacacctggtgcggcgtggcccatggatgcacc
agaaaactggggctcaagatctgcggcttcctgcaaaggaccaacagcctggaagagaag
agccggcttgtgagcgccttcaaggagaggcagtcctccaaaaacctgctttcctgtgaa
aacagcgacagggatggacgcttccggcgcacggagacggacttctccaacctgtttgct
cgagatctgcttccggctaagaacggggaagagcaaactgtgcagttcctactggaggtg
gtagacatactcctcaactatgtccgcaagacatttgatcgctccaccaaggtgctggac
ttccatcacccgcaccagctgctggaaggcatggagggcttcaacttggagctctctgac
caccctgagtccctggaacagatcttggttgactgcagagacaccctgaagtatggggtt
cgtacaggtcaccctcgatttttcaaccagctctccactggactggatatcattggttta
gctggcgaatggctgacatcaactgccaataccaatatgtttacatatgaaattgcacca
gtatttgtcctcatggagcaaataacacttaagaagatgagggagatagttggatggtca
agtaaagacggtgatgggatattttctcctgggggagccatctccaacatgtacagcatc
atggccgctcgctacaagttcttcccggaagttaagacaaagggcatggcagctgttccc
aaactggtcctcttcacctcagaacatagtcactattccataaagaaggctggagctgca
cttggctttggaaccgacaatgtgattttgataaagtgcaatgaaagggggaagataatt
ccagctgatttagaggcaaaaattcttgaagccaagcaaaagggatacgttcccctttat
gtcaatgcaactgctggtacaactgtttatggagctttcgatccgatacaggagattgca
gatatatgtgagaaatacaacctgtggctacatgtcgacgctgcctggggcggtgggctg
cttatgtccaggaagcaccgccacaaactcagtggcatagaaagggccaactcagtcacc
tggaaccctcacaagatgatgggcgtgctgttgcagtgctcggccatcctcgtcaaggaa
aagggtatactccaaggatgcaaccagatgtgtgcaggataccttttccagccagacaaa
cagtatgatgtctcctatgacactggggacaaggcaatccagtgtggccgccacgtggac
attttcaagttctggctgatgtggaaagcaaagggcacagtgggatttgaaaatcagatc
aacaaatgcttggagctggctgaatacctctatgccaagattaaaaacagagaagaattt
gagatggttttcgatggtgagcctgagcatacaaatgtctgtttctggtatattccacaa
agcctcaggggcattccagatagccctgaacgacgggaaaaactacacagggtggccccc
aaaatcaaagccctgatgatggagtctggcacgaccatggttggttaccagccccagggg
gacaaggccaactttttccggatggtcatctcgaacccagctgctacacagtctgatatt
gacttcctcatcgaggagatagaaagactgggccaggatctgtaa
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