Panthera leo (lion): 122228510
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Entry
122228510 CDS
T10741
Symbol
ATP1A1
Name
(RefSeq) sodium/potassium-transporting ATPase subunit alpha-1 isoform X1
KO
K01539
sodium/potassium-transporting ATPase subunit alpha [EC:
7.2.2.13
]
Organism
plez Panthera leo (lion)
Pathway
plez04022
cGMP-PKG signaling pathway
plez04024
cAMP signaling pathway
plez04260
Cardiac muscle contraction
plez04261
Adrenergic signaling in cardiomyocytes
plez04820
Cytoskeleton in muscle cells
plez04911
Insulin secretion
plez04918
Thyroid hormone synthesis
plez04919
Thyroid hormone signaling pathway
plez04925
Aldosterone synthesis and secretion
plez04960
Aldosterone-regulated sodium reabsorption
plez04961
Endocrine and other factor-regulated calcium reabsorption
plez04964
Proximal tubule bicarbonate reclamation
plez04970
Salivary secretion
plez04971
Gastric acid secretion
plez04972
Pancreatic secretion
plez04973
Carbohydrate digestion and absorption
plez04974
Protein digestion and absorption
plez04976
Bile secretion
plez04978
Mineral absorption
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
122228510 (ATP1A1)
04022 cGMP-PKG signaling pathway
122228510 (ATP1A1)
09140 Cellular Processes
09142 Cell motility
04820 Cytoskeleton in muscle cells
122228510 (ATP1A1)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
122228510 (ATP1A1)
04918 Thyroid hormone synthesis
122228510 (ATP1A1)
04919 Thyroid hormone signaling pathway
122228510 (ATP1A1)
04925 Aldosterone synthesis and secretion
122228510 (ATP1A1)
09153 Circulatory system
04260 Cardiac muscle contraction
122228510 (ATP1A1)
04261 Adrenergic signaling in cardiomyocytes
122228510 (ATP1A1)
09154 Digestive system
04970 Salivary secretion
122228510 (ATP1A1)
04971 Gastric acid secretion
122228510 (ATP1A1)
04972 Pancreatic secretion
122228510 (ATP1A1)
04976 Bile secretion
122228510 (ATP1A1)
04973 Carbohydrate digestion and absorption
122228510 (ATP1A1)
04974 Protein digestion and absorption
122228510 (ATP1A1)
04978 Mineral absorption
122228510 (ATP1A1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
122228510 (ATP1A1)
04961 Endocrine and other factor-regulated calcium reabsorption
122228510 (ATP1A1)
04964 Proximal tubule bicarbonate reclamation
122228510 (ATP1A1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
plez04147
]
122228510 (ATP1A1)
Enzymes [BR:
plez01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.13 Na+/K+-exchanging ATPase
122228510 (ATP1A1)
Exosome [BR:
plez04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
122228510 (ATP1A1)
Exosomal proteins of other body fluids (saliva and urine)
122228510 (ATP1A1)
Exosomal proteins of colorectal cancer cells
122228510 (ATP1A1)
Exosomal proteins of bladder cancer cells
122228510 (ATP1A1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
DUF1290
Motif
Other DBs
NCBI-GeneID:
122228510
NCBI-ProteinID:
XP_042809505
UniProt:
A0A8C9D702
LinkDB
All DBs
Position
C1:98974926..99004581
Genome browser
AA seq
1021 aa
AA seq
DB search
MGKGVGRDKYEPAAVSEHGDKKKAKKERDMDELKKEVSMDDHKLSLDELHRKYGTDLSRG
LTTARAAEILARDGPNALTPPPTTPEWVKFCRQLFGGFSMLLWIGAILCFLAYGIQAATE
EEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINA
EEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNI
AFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFL
GVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE
AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKSSATWLALS
RIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRDRYTKIVEIPF
NSTNKYQLSIHKNPNTSEPRHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAY
LELGGLGERVLGFCHLYLPDEQFPEGFQFDTDDVNFPVENLCFVGLISMIDPPRAAVPDA
VGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKA
CVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDS
PALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTS
NIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTD
KLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPTHLLGLRVDWDDRWINDVEDSY
GQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEET
ALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETY
Y
NT seq
3066 nt
NT seq
+upstream
nt +downstream
nt
atggggaaaggggttggacgtgataaatatgaacctgcggctgtttcagagcatggcgac
aaaaagaaggccaagaaagagagggatatggatgaattgaagaaagaagtttctatggat
gaccataaacttagccttgacgaacttcaccgtaaatatggaacagacctgagccgaggc
ttaacaaccgctcgagctgctgagatcctggcccgagacggccccaacgccctcacccca
cctcccaccactcccgaatgggtcaagttctgtcggcaactgtttggcgggttctcaatg
ttgctgtggattggagcgattctttgtttcttagcttacggcatccaggccgccacagaa
gaggaacctcaaaatgataatctgtatcttggcgtggtcctctccgctgtcgtcatcata
actgggtgtttctcctactatcaagaggctaaaagttcaaagattatggaatccttcaaa
aacatggtccctcagcaagcccttgtgattcgaaacggtgagaaaatgagcatcaatgcc
gaggaggttgtagtcggggatctggtggaagtgaaaggaggagaccgaatccctgccgat
ctcagaatcatatctgccaacggctgcaaggtggacaactcctcgctcactggcgaatca
gagccccagaccaggtctccggacttcacaaatgaaaaccccctggagacgaggaacatc
gccttcttttcaaccaactgtgtggaaggcaccgcacgtggcattgtcgtgtacactggg
gatcgcacggtgatgggaagaatcgcaacactcgcgtccgggctggaaggcggccagacc
cccatcgctgccgaaattgaacattttatccacatcatcacgggtgtggctgtgttcctg
ggtgtgtccttcttcattctttctctgatccttgagtacacctggctcgaggccgtcatc
tttctcatcggtatcattgtagccaacgtgccagagggtttgctggccactgtcacggta
tgtctgaccctcactgccaaacgcatggcgaggaaaaactgcttggtgaagaacttagaa
gccgtggagaccttggggtctacgtccaccatctgctcggataaaactggaactctcacc
cagaaccggatgacagtggcccacatgtggttcgacaatcagatccacgaagccgacacg
acagagaatcagagcggtgtgtcattcgacaagagttcagccacctggctcgctctgtcc
aggatcgcgggtctttgtaacagggcggtgtttcaggctaaccaggaaaacctgcctatc
ctcaagcgggcagttgcaggcgacgcctcggagtccgcgctcttgaaatgcattgagctg
tgctgtggctctgtgaaggagatgagagacagatacaccaaaatcgtggagatacccttc
aactccaccaacaagtaccagctgtctatccataagaaccccaacacgtctgagccccgg
cacctgctggtgatgaagggcgccccggagaggatcctggaccgctgtagctccatcctc
ctgcacggcaaggagcagcccctagacgaggagctgaaggacgcctttcagaacgcctac
ctggagctaggtggcctcggagagcgtgtgctaggtttctgccacctttatctgccagac
gaacagtttcctgaaggcttccagtttgacactgatgatgtgaatttccctgtggaaaac
ctctgcttcgtggggctcatctccatgatcgatcctcctcgggctgctgttcccgatgcc
gtgggcaaatgccgaagtgctggaattaaggtgataatggtcactggagaccaccccatc
acggccaaagccattgccaagggtgtgggcatcatctcagaaggcaacgagaccgtggaa
gacattgctgcccgcctcaacatcccagtgagccaggtgaaccccagagatgccaaggcc
tgcgtggtccacggaagcgacctgaaggacatgacctccgagcagctggatgacattctg
aagtaccacacggagatcgtgtttgccaggacctctcctcagcagaagcttatcatcgtg
gaaggctgccagagacagggggctatcgtggccgtgactggcgatggtgtgaatgactct
ccagccttgaagaaggcagacatcggggttgccatggggatcgctggctctgatgtgtct
aagcaagctgccgacatgattcttctggatgacaactttgcgtccattgtgactggagtc
gaagaaggtcgtctgatctttgataacttgaagaaatccattgcctacaccctgaccagt
aacattccagagatcacccccttcctgatatttattattgcaaacattccactaccactg
gggaccgtcaccatcctctgcattgacttgggcacagacatggttcctgccatctccctg
gcttacgagcaagctgagagcgacatcatgaagagacagcccagaaaccccaagacggac
aagcttgtgaacgagcggctgatcagcatggcctacgggcagatcgggatgatccaggcg
ctgggaggcttcttcacttactttgtgatcctggctgagaacggcttcctcccgacccac
ctgctggggctccgcgtggactgggatgaccgctggatcaacgacgtagaggacagctac
gggcagcagtggacgtacgaacagaggaaaatcgtggagttcacttgccacacggccttc
ttcgtcagcatcgtggtggtgcagtgggctgacctggtcatctgtaagacccggaggaac
tccgtcttccagcaggggatgaagaacaagatcttaatattcggcctctttgaagagacg
gcccttgctgccttcctttcctactgccctggaatgggcgtggccctgaggatgtacccc
ctcaaacctacctggtggttctgtgccttcccctactctcttctcatcttcgtgtacgac
gaagtccgaaaactcatcatcaggcgacgccctggcggctgggtagagaaggaaacctac
tactag
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