Panthera leo (lion): 122229202
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Entry
122229202 CDS
T10741
Symbol
MECOM
Name
(RefSeq) histone-lysine N-methyltransferase MECOM isoform X1
KO
K04462
[histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:
2.1.1.367
]
Organism
plez Panthera leo (lion)
Pathway
plez00310
Lysine degradation
plez01100
Metabolic pathways
plez04010
MAPK signaling pathway
plez05200
Pathways in cancer
plez05220
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
122229202 (MECOM)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122229202 (MECOM)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122229202 (MECOM)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
122229202 (MECOM)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
plez03000
]
122229202 (MECOM)
03036 Chromosome and associated proteins [BR:
plez03036
]
122229202 (MECOM)
Enzymes [BR:
plez01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.367 [histone H3]-lysine9 N-methyltransferase
122229202 (MECOM)
Transcription factors [BR:
plez03000
]
Eukaryotic type
Zinc finger
Cys2His2 PRDM
122229202 (MECOM)
Chromosome and associated proteins [BR:
plez03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
122229202 (MECOM)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
zf-C2H2
zf-H2C2_2
zf-C2H2_4
PRDM2_PR
zf-C2H2_6
SET
zf-C2H2_jaz
zf-H2C2_5
zf-BED
C2CH-3rd_BIRD-IDD
Zap1_zf1
zf-C2H2_8
CEP104_ZnF
Motif
Other DBs
NCBI-GeneID:
122229202
NCBI-ProteinID:
XP_042810242
LinkDB
All DBs
Position
C2:96063022..96620460
Genome browser
AA seq
1240 aa
AA seq
DB search
MRSKGRARKLATNNECVYGSYPEIPLEEMPDADGVAITPSLNIQEPCSPATSSEAFTPKE
GSPYKAPIYIPDDIPIPAEFELRESNMPGAGLGIWTKRKIEAGEKFGPYVGEQRSNLKDP
SYGWEILDEFCNVKFCVDASQPDVGSWLKYIRFAGCYDQHNLVACQINDQIFYRVVTDIA
PGEELLLFMKSEDYPHETMAPDIHEERQYRCEDCDQLFESKAELADHQKFPCSTPHSAFS
MVEEDFQQKLESENDLREIHAIQECKECDQVFPDLQSLEKHMLSHTEEREYKCDQCPKAF
NWKSNLIRHQMSHDSGKHYECENCAKQVFTDPSNLQRHIRSQHVGARAHACPECGKTFAT
SSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSS
LNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGANRHPAGL
TFPTAPGFSFSFPGLFPSGLYHRPPLIPASSPVKGLSSTEQTNKSQSPLMTHPQILPATQ
DILKALSKHPPVGDNKPVELQPERSSEERPLEKISDQSESSDLDDVSTPSGSDLETTSGS
DLESDIESDKEKFKENGKMFKDKVSPLQNLASIHNKKEYSNHSIFSPSLEEQTAVSGAVN
DSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLP
LKMEPQSPSEVKKLQKGSSESPFDLTTKRKDEKPLTPVPSKPPATPATSQDQPLDLSMGS
RSRASGTKLTEPRKNHVFGEKKGSGIEPRPASDGSLQHARPTPFFMDPIYRVEKRKLTDP
LEALKEKYLRPSPGFLFHPQFQLPDQRTWMSAIENMAEKLENFSALKPEASELLQSVPSM
FNFRAPPNALPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFS
ISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELES
TGAILDDKEDAYFTEIRNFIGNSNHSSQSPRNTEERMNGSHFKDEKALVTSQNSDLLDDE
EVEDEVLLDEEDEDNDITGKTGKEPMTSNLHEGNPEDEYEEASALEMSCKTSPVRYKEEE
YKTGLSALDHIRHFTDSLKMRKMEDNQYTEAELSSFSASHVPEELKQPLHRKSKSQAYAM
MLSLSDKESLHSTSHSSSNVWHSMARAAAESSAIQSISHV
NT seq
3723 nt
NT seq
+upstream
nt +downstream
nt
atgagatccaaaggcagggcaaggaaactggccacaaataatgagtgtgtatatggcagc
taccctgaaattcctttggaagaaatgccagatgcagatggagtagccatcactccctcc
ctcaatattcaagagccatgctctccagccacatccagcgaagcgttcactccaaaggag
ggctctccgtacaaagcccccatctacatccctgatgatatccccattcctgctgaattt
gaacttcgagagtcaaatatgcctggagctggactaggaatatggaccaaaaggaagatt
gaagcaggtgaaaagtttgggccttatgtgggagagcagcggtcaaatctgaaagacccc
agctacggatgggagatcttagatgagttttgcaatgtgaagttctgcgtagatgctagt
caaccagatgtaggaagctggctcaagtacatcaggttcgctggctgttatgatcagcac
aacctcgttgcatgccagataaatgatcagatattttatagagtagtcacagacattgca
ccaggagaggagctcctgctgttcatgaagagtgaagactatccccatgaaactatggcg
ccggatattcacgaagaacggcagtatcgctgtgaggactgtgaccagctcttcgagtcc
aaggcggagctagcagatcaccaaaagttcccgtgcagcacccctcactcagcattttcg
atggtggaagaggacttccaacaaaaactcgaaagtgagaacgatctccgagagatacat
gcgatccaggagtgtaaggaatgtgaccaagtgttccccgatttgcaaagcctggagaaa
cacatgttgtcacatactgaagagagggaatacaagtgcgatcagtgtcccaaggcattt
aactggaagtccaatttaattcgccaccagatgtcacatgacagtggaaagcactatgaa
tgtgaaaactgtgccaagcaggttttcacggaccctagcaacctccagcggcacattcgc
tctcagcatgttggtgcccgggcccacgcatgcccggagtgtggcaaaacgtttgccact
tcgtcgggcctcaaacaacacaagcacatccacagcagtgtgaagccctttatctgtgag
gtctgccataaatcctatactcagttttcaaacctttgtcgtcataagcgcatgcatgct
gattgcagaacccaaatcaagtgcaaagactgtggacaaatgttcagcactacgtcttcc
ttaaataaacacaggaggttttgtgagggcaagaaccattttgcggcaggtggatttttt
ggccaaggcatttcacttcctggaaccccagctatggataaaacgtccatggttaatatg
agtcatgccaacccgggccttgctgactattttggtgccaataggcatcctgctggtctt
acctttccaacagctcctggattttcttttagcttccctggtctgtttccttccggcttg
taccacaggcctcctttgatacctgctagttctcctgttaaaggactatcaagtactgaa
cagacaaacaaaagtcaaagtcccctcatgacacatcctcagatactgccagctacacag
gatattttgaaggcactatctaaacacccacctgtaggggacaataagccagtggagctc
cagcccgagaggtcctctgaagagaggccccttgagaaaatcagtgaccagtcagagagt
agtgaccttgatgatgtcagtacgccaagtggcagtgacctggaaacaacctcgggctct
gatctggaaagtgacattgaaagtgataaagagaaatttaaagaaaatggtaaaatgttc
aaagacaaagtaagccctcttcagaatctggcttcaatacataataagaaagaatacagc
aatcattccattttctcaccatctttagaggagcaaactgcggtgtcaggagctgtgaat
gattctataaaagctattgcttctattgctgaaaaatactttggttcaacaggactggtg
gggctgcaagacaaaaaagttggagctttaccttacccttccatgtttcccctcccgttt
tttccagcattctctcaatcaatgtacccatttcctgatagagacttgagatcgttacct
ttgaaaatggaaccccaatcaccaagtgaagtaaagaaactgcagaagggaagctctgag
tctccctttgatctcaccactaagcgaaaggacgagaagcccttgactccagtcccctcc
aagcctccagcaacacctgccacaagccaagaccagcccctggatctaagtatgggcagt
aggagtagagccagtgggacaaagctgaccgagcctcgtaaaaaccacgtgtttggggaa
aagaaaggaagcggcattgaaccaagaccagcatcagatggttccttgcagcatgctaga
cccactcctttctttatggaccctatttacagagtagagaaaagaaaactaactgaccca
cttgaagctttaaaagagaaatacttgagaccttcgccaggattcttatttcacccacaa
ttccaactgcctgatcagagaacttggatgtcagctattgaaaacatggcagagaagctc
gagaacttcagtgccctgaaaccagaggccagtgaacttctgcagtcagttccctccatg
ttcaatttcagagcgcctcccaatgccctgccagagaacctcctgcggaaaggaaaagaa
cgctacacgtgcagatactgtggcaagatttttccaaggtctgcgaacttaacacggcac
ctgagaacccacacaggagagcagccttacagatgcaaatactgtgaccgatcatttagc
atctcttccaacttgcaaaggcatgttcgtaatatccacaataaggagaagccctttaag
tgtcacttatgtgataggtgttttggtcaacaaaccaacttagacagacacctaaagaaa
catgagaatgggaacatgtcgggtacggccacgtcgtcgcctcattccgaactggaaagt
acaggcgcgattcttgatgacaaagaagatgcttacttcacagaaattcgcaatttcatt
gggaacagcaaccacagcagccagtctcccaggaacacagaggagaggatgaacggcagt
cattttaaggatgagaaggctttggtgaccagtcaaaattcagatttactggatgacgaa
gaagtagaagacgaggtgttgttagatgaggaggacgaagacaatgatattactggaaaa
acaggaaaggaacccatgacaagcaatttacatgaaggaaatcctgaggatgagtatgaa
gaagccagtgccctggagatgagttgcaaaacgtctccagtgaggtataaagaggaagaa
tataaaactggactttctgctctagatcatataaggcacttcacagatagcctcaaaatg
aggaaaatggaagataatcaatatactgaagctgagctgtcttcttttagtgcttcccat
gtgccggaggaacttaaacagccgttacacagaaagtccaagtcacaggcatatgctatg
atgttgtcattgtccgacaaggagtccctccattctacatcccacagttcttccaacgtg
tggcacagtatggcaagggctgctgcggaatccagtgccatccagtccataagccacgta
tga
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integrated database retrieval system
