Panthera leo (lion): 122229432
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Entry
122229432 CDS
T10741
Symbol
MLH1
Name
(RefSeq) DNA mismatch repair protein Mlh1 isoform X1
KO
K08734
DNA mismatch repair protein MLH1
Organism
plez Panthera leo (lion)
Pathway
plez01524
Platinum drug resistance
plez03430
Mismatch repair
plez03460
Fanconi anemia pathway
plez05200
Pathways in cancer
plez05210
Colorectal cancer
plez05213
Endometrial cancer
plez05226
Gastric cancer
Brite
DNA repair and recombination proteins [BR:
plez03400
]
Eukaryotic type
SSBR (single strand breaks repair)
MMR (mismatch excision repair)
MutL homologs
122229432 (MLH1)
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Gene cluster
GFIT
Other DBs
NCBI-GeneID:
122229432
NCBI-ProteinID:
XP_042810460
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Position
C2:complement(153132988..153176210)
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AA seq
776 aa
AA seq
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MSLVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKATSIQVVVKEGGLKLIQ
IQDNGTGIRKEDLDIVCERFTTSKLQSFEDLASISTYGFRGEALASISHVAHVTITTKTA
DAKCAYRASYSDGKLTTPPKPCAGNQGTQITVEDLFYNISTRRKALKNPSEEYGKILEVV
GRYSIHNSGIGFSVKKQGETVADVRTLPSATTVDNIRSIFGNAVSRELIEVGCEDKTLAF
KMNGFISNANYSVKKCIFLLFINHRLVESTSLRKAIETVYAAYLPKNTHPFLYLSRISLN
ASHVPAAVLVKQSLEISPQNVDVNVHPTKHEVHFLHEDSILERVQQHVESKLLGSNSSRM
YFTQTLLPGLAGPSGEVVKSTVGVPPSSTSGSGDKVYAHQMVRTDSREQKLDAFMQPVSK
ALSGQPQAVVPEDGPEASSGRARQQDEEMLELPEPAAVAATNQGLEGDATEVTSQASEKR
GPPSSPGNPRKRPRESSDVEMVEDDSRKEMTAACTPRRRIINLTSVLSLQEEINERGHET
LREMLHNHSFVGCVNPQWALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPA
PLFDLAMLALDSPESGWTEEDGPKEGLAEYIVEFLKKKAEMLADYFSLEIDEEGNLIGLP
LLIDNYVPPLEGLPLFILRLATEVNWDEEKECFESLSKECAMFYSVRKQYVCEESTLSGQ
QSDAPGSSANPWKWTVEHVVYKAFRSHLLPPKRFTEDGNILQLANLPDLYKVFERC
NT seq
2331 nt
NT seq
+upstream
nt +downstream
nt
atgtcgctcgtagcgggggttattcggcggctggacgaaacagtggtgaaccgcatcgcg
gcaggggaagtcatccagcggccggccaacgccatcaaggagatgattgagaactgctta
gatgcaaaagccaccagcatccaagtggttgttaaagagggaggcctcaagttgattcag
atccaagacaatggcactgggatccggaaagaagatctggatattgtgtgtgagaggttc
actacaagtaaactgcagtcctttgaggatttagctagtatttctacctatggctttcgg
ggtgaggctttggccagcatcagccacgtggctcacgttaccattacaaccaaaacagct
gatgcaaagtgcgcatacagagcaagttactcagatggaaagctgacaactcctcctaaa
ccatgtgcaggcaatcaggggacccagattacagtggaagatctcttttacaacatatcc
acaaggaggaaagctttaaaaaatccgagtgaagagtatgggaaaattttggaagttgtt
ggcaggtattcaatacacaattcaggcattggtttctcagttaaaaaacaaggcgagaca
gtggctgacgttagaacactgcccagtgccacaactgtagacaatattcgctccatcttt
ggaaatgctgttagccgagaactgatagaagtcgggtgtgaggataaaaccctagccttc
aaaatgaatggctttatatccaatgcaaattactccgtgaagaagtgtatcttcttactc
ttcatcaaccatcgtctggtagagtcaacttccttaagaaaagccattgaaaccgtgtat
gcagcctatttgcccaaaaacacacacccgttcctgtacctcagcagaatctcactgaac
gcctcccacgtgccagccgctgtgttggtgaaacaaagtttggagatcagcccccagaac
gtggatgtcaacgtgcaccccacaaagcacgaggttcacttcctacacgaggacagcatc
ctggagcgggtgcaacagcacgttgagagcaagctcctgggctccaactcgtccaggatg
tacttcacccagactttactcccaggtcttgccggcccctccggggaggtggttaagtcc
acagtgggtgtgcccccctcatccacttctggaagcggcgacaaggtctatgctcaccag
atggtccgcacagattcgcgggaacagaagctcgatgcgtttatgcagcctgtgagcaag
gctctgtccggtcagcctcaggccgtggtcccagaagatgggcctgaggcttccagcggc
agggccaggcagcaggatgaggaaatgctcgaactcccggagcctgctgcagtggctgcc
acaaatcagggcttggagggggatgcaacagaggtgacttcacaagcgtcggagaagaga
gggcccccttccagcccaggtaaccccagaaagaggccccgggaaagctctgatgtggaa
atggtggaagatgattcccggaaggaaatgacggcggcttgtactccccggagaaggatc
atcaacctcaccagtgtcctgagcctccaggaagaaattaatgagcggggacatgagact
ctccgagagatgctgcacaaccactccttcgtgggctgcgtgaatcctcagtgggccttg
gcacagcatcagaccaagctataccttctcaacaccaccaaacttagtgaagaactgttc
taccagatactcatttatgattttgccaattttggtgttctgaggctgtcggagccagcg
ccgctctttgacctggccatgctcgccttagacagtcccgagagtggctggacagaggag
gatggccccaaagaaggacttgctgagtacattgttgagtttctgaagaagaaggctgag
atgcttgcggactatttctccttggagatcgatgaggaagggaacctgattggattaccc
ctgctgatcgacaactacgtgccccctttggagggcctgcctctcttcattcttcgacta
gccaccgaggtgaactgggatgaagaaaaggaatgttttgaaagcctcagcaaagagtgt
gctatgttttactccgttcggaagcagtatgtatgtgaggagtcgaccctctcaggccag
cagagtgacgcgcccggctcctcagcaaacccctggaagtggactgtggaacacgtcgtc
tataaagccttccgctcacaccttctgcctcctaaacgtttcacggaagatggaaatatc
ctacagcttgccaacctgcccgatctatacaaagtcttcgagagatgttaa
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