Panthera leo (lion): 122229459
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Entry
122229459 CDS
T10741
Symbol
ACVR2B
Name
(RefSeq) activin receptor type-2B isoform X1
KO
K13596
activin receptor type-2B [EC:
2.7.11.30
]
Organism
plez Panthera leo (lion)
Pathway
plez04060
Cytokine-cytokine receptor interaction
plez04350
TGF-beta signaling pathway
plez04550
Signaling pathways regulating pluripotency of stem cells
plez05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
122229459 (ACVR2B)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
122229459 (ACVR2B)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
122229459 (ACVR2B)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
122229459 (ACVR2B)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plez01001
]
122229459 (ACVR2B)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
122229459 (ACVR2B)
Protein kinases [BR:
plez01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR2 family [OT]
122229459 (ACVR2B)
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Paralog
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Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Activin_recp
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
122229459
NCBI-ProteinID:
XP_042810526
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Position
C2:complement(151822246..151865808)
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AA seq
532 aa
AA seq
DB search
MRREHTRCGATGEATGHVPLSQAAWVRNLVLALDNNLGSGRGEAETRECIYYNANWEQER
TNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVY
FCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMY
RHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFP
LQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSSLEVELWLITAFHDKGSLTDYLKGN
IITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADF
GLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRC
KAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPAIKDHWLKHPGLAQLCVTIEEC
WDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI
NT seq
1599 nt
NT seq
+upstream
nt +downstream
nt
atgcgccgggaacacacgcgttgcggagctacaggggaggccacagggcatgtaccgttg
agccaggctgcctgggttcgaaacctggttttggccctcgataataacttgggttccggg
cgtggggaggccgagacccgggagtgcatttactacaacgccaactgggagcaggagcgc
accaaccagagcggcctggagcgctgcgagggcgagcaggacaagcggctgcactgctac
gcctcctggcgcaacagctcgggcaccatcgagctcgtcaagaagggctgctggctggac
gacttcaactgctatgacaggcaggagtgtgtggccaccgaggagaacccccaggtgtac
ttctgctgctgtgaaggcaacttctgcaacgagcgcttcacccacttgccagaggctggg
ggcccagaagtcacgtacgagccacccccgacagcccccaccctgctcacggtgctggcc
tactcgctgctgcccattgggggcctctccctcatcgtcttgctggccttctggatgtac
cggcatcgcaagcccccctacggccacgtggacatccacgaggaccctgggcctccacct
ccatcccctctggtgggcctgaagccactgcagctgctggagatcaaggcccgggggcgc
tttggttgtgtctggaaggcacagctcatgaatgactttgtggctgtcaagatcttcccg
ctccaggacaagcagtcatggcagagcgaacgggagatcttcagcacacccggcatgaag
catgagaacctgctgcagttcatcgccgctgagaagcgaggctccagccttgaggtggag
ctgtggctcatcacagctttccatgacaagggctccctcacggattacctcaaggggaac
atcatcacgtggaacgagctgtgtcacgtggcagagaccatgtcaagaggcctctcatac
cttcacgaggatgtgccctggtgccgtggcgagggccacaagccgtctattgcccacagg
gactttaaaagcaagaatgtattgctcaagagcgacctcacagccgtgctggctgacttt
ggtctggctgttcggtttgagccagggaaaccgccgggggacactcatgggcaggtgggc
acgcggcgttacatggcccctgaggtgcttgagggagccatcaacttccagagagatgcc
ttcctgcgcatcgacatgtatgccatggggctggtgctgtgggagcttgtgtcgcgctgc
aaggccgcggacggacccgtggacgagtacatgctgccctttgaggaagagatcggccag
cacccatcactggaggagctgcaggaggtggtcgtgcacaagaagatgcggcccgccatt
aaggatcactggctgaagcacccgggcctggcccagctctgtgtaaccatcgaggagtgc
tgggaccacgacgcggaggctcgcctgtctgcgggctgcgtggaagagcgcgtgtccctg
atccggaggtcggtcaacggcactacctcggactgtcttgtctccctggtgacctccgtc
accaacgtggacctgccccctaaggagtcgagcatctaa
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