Panthera leo (lion): 122229762 Help Entry 122229762         CDS       T10741                                  Symbol PLD1 Name (RefSeq) phospholipase D1 isoform X1   KO K01115   phospholipase D1/2 [EC:3.1.4.4] Organism plez  Panthera leo (lion) Pathway plez00564   Glycerophospholipid metabolism plez00565   Ether lipid metabolism plez01100   Metabolic pathways plez04014   Ras signaling pathway plez04024   cAMP signaling pathway plez04071   Sphingolipid signaling pathway plez04072   Phospholipase D signaling pathway plez04144   Endocytosis plez04666   Fc gamma R-mediated phagocytosis plez04724   Glutamatergic synapse plez04912   GnRH signaling pathway plez04928   Parathyroid hormone synthesis, secretion and action plez05200   Pathways in cancer plez05208   Chemical carcinogenesis - reactive oxygen species plez05212   Pancreatic cancer plez05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:plez00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     122229762 (PLD1)    00565 Ether lipid metabolism     122229762 (PLD1)  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     122229762 (PLD1)    04072 Phospholipase D signaling pathway     122229762 (PLD1)    04071 Sphingolipid signaling pathway     122229762 (PLD1)    04024 cAMP signaling pathway     122229762 (PLD1)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     122229762 (PLD1)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     122229762 (PLD1)   09152 Endocrine system    04912 GnRH signaling pathway     122229762 (PLD1)    04928 Parathyroid hormone synthesis, secretion and action     122229762 (PLD1)   09156 Nervous system    04724 Glutamatergic synapse     122229762 (PLD1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     122229762 (PLD1)    05208 Chemical carcinogenesis - reactive oxygen species     122229762 (PLD1)    05231 Choline metabolism in cancer     122229762 (PLD1)   09162 Cancer: specific types    05212 Pancreatic cancer     122229762 (PLD1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:plez04131]     122229762 (PLD1) Enzymes [BR:plez01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.4  Phosphoric-diester hydrolases     3.1.4.4  phospholipase D      122229762 (PLD1) Membrane trafficking [BR:plez04131]  Exocytosis   Calcium ion-dependent exocytosis    Phospholipases     122229762 (PLD1)  Endosome - Golgi transport   Others    Others     122229762 (PLD1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PLDc PX PLDc_2 PH zf-C2H2_7th_ZNF462 DUF3785 Motif Other DBs NCBI-GeneID:  122229762 NCBI-ProteinID:  XP_042811158 UniProt:  A0A8C8XEM5 LinkDB All DBs Position C2:94178473..94377817 Genome browser AA seq 1074 aa AA seqDB search MSLKNEPRVNTSALQKIAADMSNLIENLDTRELHFEGEEVDYDVSPSDPKIQEVCIPFSA IYKTQGFKEPNIQTYLTGCPIKAQVLEVERFTSTTRVPSINLYTIELTHGEFKWQVKRKF KHFQEFHRELLKYKAFIRIPIPTRRHTFRRQNVKEEPREMPSLPRSSENMIREEQFFSRR KQLEDYLTKLLKMPMYRNYHATTEFLDISQLSFIHDLGPKGIEGMIMKRSGGHRIPGLNC CGQGRACYRWSKRWLIVKDSFLLYMKPDSGAIAFVLLVDKEFKIKVGKKETETKYGLRID NLSRTLILKCNSYRHARWWGGAIEEFIQKYGTNFLKDHRFGSYAAIQENTLAKWYVNAKG YFEDVANAMEEAQEEIFITDWWLSPEIFLKRPVVEGNRWRLDCILKRKAQEGVRIFIMLY KEVELALGINSEYSKRTLMRLHPNIKVMRHPDHVSSSVYLWAHHEKIVVIDQSVAFVGGI DLAYGRWDDNEHRLTDVGSVKRVTVGPSLSSFTAETTESMESLSLQDKNKASNNLPTLRS VDDMDSKLKGVGKSRKFSKFSLYRHLHRHHLHDADSISSIDSASSYCNHCRSRQNLIHGL KPHLKLFHSSSKSEQGLTRPNVDTSSLRSLQTGMGELHGETRFWHGKDYCNFVFKDWVQL DKPFADFIDRHSTPRMPWHDIASAVHGKAARDVARHFIQRWNFTKIMKSKYRSLSYPFLL PKSQTTAHELKYQVPGSVHANVQLLRSAADWSAGIKYHEESIHTAYIHVIENSKHYIYIE NQFFISCADDKVVFNKIGDAIAQRILKAHRENQRYRVYVVIPLLPGFEGDISTGGGNALQ AIMHFNYRTMCRGENSILGQLKAKLGNQWINYISFCGLRTHAELEGNLVTELIYVHSKLL IADDNTVIIGSANINDRSMLGKRDSEMAVIVQDTETVPSVMDGEEYQAGRFAQGLRLQSF RVVLGYLSDPSENIQDPVSDKFFKEVWVATAARNATIYDKVFRCLPNDEVHNLIQLRDFI SKPILAKEDPIRAEEELKKIRGFLVQFPFYFLSEESLLPSVGTKEAIVPTEVWT NT seq 3225 nt NT seq  +upstreamnt  +downstreamnt atgtcactgaaaaatgagccacgagtaaatacctctgcactgcagaaaatcgctgctgac atgagtaatttgatagaaaatctggacacacgggagctgcactttgagggagaagaggtg gattatgatgtgtctcccagcgatcccaagatacaggaagtgtgtattcctttctctgct atttataagactcaaggatttaaggagcctaatatacagacgtatctcaccggctgtcca ataaaagcccaagttctggaagtggagcgctttacatctacaacaagggtaccaagtatc aatctttacactattgaattaacacatggggaatttaaatggcaagttaagaggaaattc aaacactttcaagaatttcatagagagctgctcaagtacaaagcttttatccgaatcccc attcccaccagaaggcacacgtttagaagacagaatgtcaaagaagagcctcgagagatg ccaagtttgccccgttcatctgaaaacatgatcagagaagaacaattcttcagtagaagg aaacaactggaagattatttgacaaagctactgaaaatgcccatgtatagaaactaccat gcaacaacagaattccttgacataagccagctgtctttcatccatgatttgggaccaaag ggcatagaaggtatgataatgaagagatccgggggacacagaataccaggcttgaattgc tgtggtcagggaagagcctgctaccgctggtcaaaaaggtggttgatagtgaaagattcc ttcttactatatatgaaaccagacagtggtgccattgccttcgtcctgctggtagataaa gaattcaaaatcaaggtggggaagaaggagacagagacaaaatacgggctccgaattgat aatctttcaaggactcttattttaaaatgcaacagctatagacatgctcggtggtgggga ggggctatagaagaattcatccagaaatatggtaccaactttctcaaagaccatcgattc gggtcctatgctgctatccaagagaatacattagccaaatggtacgttaatgccaaagga tattttgaagatgtggcaaatgcaatggaagaggcacaagaagagatttttatcacggat tggtggctgagtccagaaatcttcctgaaacgcccggtggttgaaggaaatcgttggagg ttggactgcattcttaaacgaaaagcacaagagggggtgagaatcttcataatgctctac aaagaggtggaactcgctcttggaatcaacagtgaatacagcaagaggactttaatgcgt ctacaccccaacataaaggtgatgaggcacccagatcatgtatcatccagcgtgtatctg tgggctcatcatgagaaaattgttgtcatcgaccagtcagtggcttttgtgggtgggatc gacctggcctatggaaggtgggatgacaatgaacacagactcacggacgtgggcagcgtg aagcgtgtcactgtaggaccatctctgagttccttcacagctgaaacaacagagtccatg gaatccttaagccttcaagataaaaacaaagctagtaacaatctgcccaccctgaggagc gttgatgatatggattcaaaactgaaaggagtaggaaaatccagaaagttctcgaaattt agcctctacagacacctccacaggcaccacctgcacgatgcagacagcatcagcagcatt gacagtgcctccagttattgtaatcactgtagaagtcgtcagaatttaatccatggttta aaaccccacctgaaactctttcactcttccagtaagtctgagcagggactcactagacct aatgttgacaccagctccctccgcagtttacagacaggcatgggagagctccatggggaa accaggttctggcatggaaaggactactgcaattttgtcttcaaagactgggttcaactt gataaaccttttgctgatttcattgacaggcactccactccccggatgccatggcatgac attgcctctgcagttcacgggaaggcagctcgtgacgtagcacgtcacttcatccagcgc tggaacttcacgaagataatgaaatcaaagtatcggtccctttcgtatccttttctgctt ccaaaatctcaaacaacagcccatgagctgaaatatcaagtgcctgggtcggtccatgcc aatgtacagttgctccgctctgctgctgattggtcggctggtataaagtaccatgaagag tccatccatactgcttatatccatgtgatagagaacagcaagcactatatctacatagag aaccagtttttcataagttgtgctgatgacaaagttgtgttcaacaagataggtgatgcc attgctcagaggatcctgaaagctcacagggaaaaccagagataccgggtgtatgttgtg ataccgctgctgccaggatttgaaggagacatttcaacgggtggaggaaatgctctgcag gcaataatgcacttcaactacagaaccatgtgcagaggagaaaattccatccttgggcag ttaaaagcaaaacttggcaatcagtggataaattacatatcattctgtggccttagaacg catgcagagcttgaaggaaacctagtcactgagctcatctatgtccacagcaagttgcta attgctgatgacaacactgttattattggctctgccaacataaacgaccgaagcatgctg gggaagcgtgacagtgaaatggctgtcattgtacaggacacagagacagtcccttcagta atggatggggaagaataccaagctggccggttcgcccaaggacttcggctgcagagcttc agggttgtccttggctatctttctgacccaagcgaaaacattcaggatccagtgagtgac aaattcttcaaggaggtatgggttgcaacggcagctcgaaatgctacaatttatgataag gtgttccggtgccttcccaatgatgaagtacacaatttaattcaattgagagactttatt agcaagcccatattagcaaaggaggatcccattagagccgaggaagaactgaaaaagatc cgtgggttcttggtgcaattccccttttatttcttgtctgaagaaagcctactgccttcc gttggaaccaaagaagccatagtgcccacagaggtttggacttaa

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