KEGG   Perognathus longimembris pacificus (Pacific pocket mouse): 125339698
Entry
125339698         CDS       T08928                                 
Symbol
Fgfr1
Name
(RefSeq) fibroblast growth factor receptor 1 isoform X1
  KO
K04362  fibroblast growth factor receptor 1 [EC:2.7.10.1]
Organism
plop  Perognathus longimembris pacificus (Pacific pocket mouse)
Pathway
plop04010  MAPK signaling pathway
plop04014  Ras signaling pathway
plop04015  Rap1 signaling pathway
plop04020  Calcium signaling pathway
plop04151  PI3K-Akt signaling pathway
plop04520  Adherens junction
plop04550  Signaling pathways regulating pluripotency of stem cells
plop04714  Thermogenesis
plop04810  Regulation of actin cytoskeleton
plop04928  Parathyroid hormone synthesis, secretion and action
plop05200  Pathways in cancer
plop05205  Proteoglycans in cancer
plop05215  Prostate cancer
plop05218  Melanoma
plop05224  Breast cancer
plop05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:plop00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    125339698 (Fgfr1)
   04014 Ras signaling pathway
    125339698 (Fgfr1)
   04015 Rap1 signaling pathway
    125339698 (Fgfr1)
   04020 Calcium signaling pathway
    125339698 (Fgfr1)
   04151 PI3K-Akt signaling pathway
    125339698 (Fgfr1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    125339698 (Fgfr1)
   04550 Signaling pathways regulating pluripotency of stem cells
    125339698 (Fgfr1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    125339698 (Fgfr1)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    125339698 (Fgfr1)
  09159 Environmental adaptation
   04714 Thermogenesis
    125339698 (Fgfr1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    125339698 (Fgfr1)
   05205 Proteoglycans in cancer
    125339698 (Fgfr1)
   05230 Central carbon metabolism in cancer
    125339698 (Fgfr1)
  09162 Cancer: specific types
   05218 Melanoma
    125339698 (Fgfr1)
   05215 Prostate cancer
    125339698 (Fgfr1)
   05224 Breast cancer
    125339698 (Fgfr1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:plop01001]
    125339698 (Fgfr1)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:plop04090]
    125339698 (Fgfr1)
   00536 Glycosaminoglycan binding proteins [BR:plop00536]
    125339698 (Fgfr1)
Enzymes [BR:plop01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     125339698 (Fgfr1)
Protein kinases [BR:plop01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   125339698 (Fgfr1)
CD molecules [BR:plop04090]
 Proteins
  125339698 (Fgfr1)
Glycosaminoglycan binding proteins [BR:plop00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   125339698 (Fgfr1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set ig Ig_3 Ig_2 V-set C2-set_2 Ig_4 ABC1 V-set_CD47 Pkinase_fungal DUF1615 zf-CCCH_9
Other DBs
NCBI-GeneID: 125339698
NCBI-ProteinID: XP_048186906
LinkDB
Position
21:33312359..33367810
AA seq 822 aa
MWSWKCLLFWAVLVTATLCTARPAPTLPEQAQPWGAPEEVESLLVHPGDLLQLRCRLRDD
VQSINWLRDGVQLVESNRTRITGEEVEVRDSVPADSGLYACVTSSPSGSDTTYFSVNVSD
ALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPS
SGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSIN
HTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKI
GPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLE
ALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIIYKMKSGTKKSDFHSQMAVHKLAKS
IPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVL
GKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGK
HKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDL
VSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNG
RLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMD
KPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSF
PDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPTPLANGGLKRR
NT seq 2469 nt   +upstreamnt  +downstreamnt
atgtggagctggaagtgcctcctcttctgggctgtgctggtcacagccacactctgtact
gccaggccggcccccaccttgcctgaacaagctcagccttggggagcccctgaggaagtg
gagtccctcctggtccaccccggtgacctgctgcagctccgctgtcggctgcgggacgat
gtgcagagcatcaactggctgcgggatggggtgcagctggtggagagcaaccgtacccgc
atcacaggggaggaggtggaggtgcgggattctgtgcccgctgactctggcctctacgct
tgtgtgaccagcagcccctctggcagcgataccacctacttctccgtcaatgtctcagat
gccctcccctcctcggaggatgacgacgacgatgatgactcctcctcagaggagaaagag
acagataacaccaaaccaaaccgtatgcctgtggctccatactggacatccccagaaaag
atggaaaagaaattgcatgcagtgccagctgccaagacagtgaagttcaaatgtccttcc
agtgggactccgaaccccacactgcgttggctgaagaatggcaaagagttcaaacctgac
cacaggattggaggctacaaggtccgttacgccacatggagcatcataatggactcagtg
gtgccctccgataagggcaactatacctgcatcgtggagaatgagtatggcagcataaac
cacacgtaccagctggatgttgtggagcggtcccctcaccggcccatcctgcaagctggg
ttgcctgccaacaagacagtggccctgggcagcaatgtggagttcatgtgtaaagtatac
agcgacccacagccccatatccagtggctaaagcacatcgaggtgaatgggagtaagatt
ggtccggacaacctgccttatgtccagatcttgaagacggccggagttaataccaccgac
aaagagatggaggtgcttcacttgcgaaatgtctcctttgaggacgcgggggagtatacg
tgcttggcgggtaactctatcggactctcccatcactctgcatggttgaccgtgttggaa
gccctggaagagaggccggccgtgatgacctcacccctctacctggagatcatcatctac
tgcacgggggccttcctcatctcctgcatggtgggctctgtcatcatctacaagatgaag
agtggcaccaagaagagcgacttccacagccagatggctgtgcacaagctggccaagagc
attcctctgcgcagacaggtaacagtgtcggctgactccagtgcatccatgaactccggg
gttcttctagttcggccctcacggctctcttccagcgggactcctatgctagctggagtc
tcagaatatgagcttcccgaagacccccgttgggagctgccccgagacaggttggtctta
ggcaagccactgggagagggctgctttgggcaggtggtgttggcagaggccatcgggcta
gacaaggacaaacccaaccgcgtgaccaaagtagctgtgaagatgttgaagtcggacgca
acagagaaggacctgtcagaccttatctcagagatggagatgatgaagatgattgggaaa
cacaagaatatcatcaacctgctgggagcctgtacacaggatggtcctctgtatgtcatt
gtggagtatgcctccaagggcaatctccgagagtacctgcaggcccggaggcccccagga
ctggaatactgctataaccccagccacaacccggaggaacagctctcttccaaggacctg
gtatcctgtgcctatcaggtggcccgaggcatggagtatcttgcttctaagaagtgcatc
caccgagacctggccgccaggaacgtgctggtgacagaagacaacgtgatgaagatcgca
gacttcggcctggcccgggacatccaccacatcgactactataaaaagacaaccaacggc
cggctgcctgtgaagtggatggcacccgaggccttgtttgaccggatctacacccaccag
agtgatgtgtggtcttttggggtgcttctatgggaaatcttcaccctgggcggctccccg
taccctggtgtgcctgtggaagagcttttcaagctgctgaaggagggccatcggatggac
aagcctagtaactgcaccaacgagctgtacatgatgatgcgggactgctggcatgcagtg
ccctcccagaggcctaccttcaagcagttggtggaagacctggaccgcattgtggccttg
acttccaaccaggagtatctggacctgtccatgcctctggaccagtactcccccagcttt
cccgatacccgaagctctacctgctcctcgggggaggattctgtcttctctcatgagcca
ttgcccgaggagccctgtctgccccgacatcccaccccactagccaacggcggactcaag
cgacgctga

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