KEGG   Perognathus longimembris pacificus (Pacific pocket mouse): 125340801
Entry
125340801         CDS       T08928                                 
Symbol
Mapk3
Name
(RefSeq) mitogen-activated protein kinase 3
  KO
K04371  mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
plop  Perognathus longimembris pacificus (Pacific pocket mouse)
Pathway
plop01521  EGFR tyrosine kinase inhibitor resistance
plop01522  Endocrine resistance
plop01524  Platinum drug resistance
plop04010  MAPK signaling pathway
plop04012  ErbB signaling pathway
plop04014  Ras signaling pathway
plop04015  Rap1 signaling pathway
plop04022  cGMP-PKG signaling pathway
plop04024  cAMP signaling pathway
plop04062  Chemokine signaling pathway
plop04066  HIF-1 signaling pathway
plop04068  FoxO signaling pathway
plop04071  Sphingolipid signaling pathway
plop04072  Phospholipase D signaling pathway
plop04114  Oocyte meiosis
plop04140  Autophagy - animal
plop04148  Efferocytosis
plop04150  mTOR signaling pathway
plop04151  PI3K-Akt signaling pathway
plop04210  Apoptosis
plop04218  Cellular senescence
plop04261  Adrenergic signaling in cardiomyocytes
plop04270  Vascular smooth muscle contraction
plop04350  TGF-beta signaling pathway
plop04360  Axon guidance
plop04370  VEGF signaling pathway
plop04371  Apelin signaling pathway
plop04380  Osteoclast differentiation
plop04510  Focal adhesion
plop04517  IgSF CAM signaling
plop04520  Adherens junction
plop04540  Gap junction
plop04550  Signaling pathways regulating pluripotency of stem cells
plop04611  Platelet activation
plop04613  Neutrophil extracellular trap formation
plop04620  Toll-like receptor signaling pathway
plop04621  NOD-like receptor signaling pathway
plop04625  C-type lectin receptor signaling pathway
plop04650  Natural killer cell mediated cytotoxicity
plop04657  IL-17 signaling pathway
plop04658  Th1 and Th2 cell differentiation
plop04659  Th17 cell differentiation
plop04660  T cell receptor signaling pathway
plop04662  B cell receptor signaling pathway
plop04664  Fc epsilon RI signaling pathway
plop04666  Fc gamma R-mediated phagocytosis
plop04668  TNF signaling pathway
plop04713  Circadian entrainment
plop04720  Long-term potentiation
plop04722  Neurotrophin signaling pathway
plop04723  Retrograde endocannabinoid signaling
plop04724  Glutamatergic synapse
plop04725  Cholinergic synapse
plop04726  Serotonergic synapse
plop04730  Long-term depression
plop04810  Regulation of actin cytoskeleton
plop04910  Insulin signaling pathway
plop04912  GnRH signaling pathway
plop04914  Progesterone-mediated oocyte maturation
plop04915  Estrogen signaling pathway
plop04916  Melanogenesis
plop04917  Prolactin signaling pathway
plop04919  Thyroid hormone signaling pathway
plop04921  Oxytocin signaling pathway
plop04926  Relaxin signaling pathway
plop04928  Parathyroid hormone synthesis, secretion and action
plop04929  GnRH secretion
plop04930  Type II diabetes mellitus
plop04933  AGE-RAGE signaling pathway in diabetic complications
plop04934  Cushing syndrome
plop04935  Growth hormone synthesis, secretion and action
plop04960  Aldosterone-regulated sodium reabsorption
plop05010  Alzheimer disease
plop05020  Prion disease
plop05022  Pathways of neurodegeneration - multiple diseases
plop05034  Alcoholism
plop05132  Salmonella infection
plop05133  Pertussis
plop05135  Yersinia infection
plop05140  Leishmaniasis
plop05142  Chagas disease
plop05145  Toxoplasmosis
plop05152  Tuberculosis
plop05160  Hepatitis C
plop05161  Hepatitis B
plop05163  Human cytomegalovirus infection
plop05164  Influenza A
plop05165  Human papillomavirus infection
plop05166  Human T-cell leukemia virus 1 infection
plop05167  Kaposi sarcoma-associated herpesvirus infection
plop05170  Human immunodeficiency virus 1 infection
plop05171  Coronavirus disease - COVID-19
plop05200  Pathways in cancer
plop05203  Viral carcinogenesis
plop05205  Proteoglycans in cancer
plop05206  MicroRNAs in cancer
plop05207  Chemical carcinogenesis - receptor activation
plop05208  Chemical carcinogenesis - reactive oxygen species
plop05210  Colorectal cancer
plop05211  Renal cell carcinoma
plop05212  Pancreatic cancer
plop05213  Endometrial cancer
plop05214  Glioma
plop05215  Prostate cancer
plop05216  Thyroid cancer
plop05218  Melanoma
plop05219  Bladder cancer
plop05220  Chronic myeloid leukemia
plop05221  Acute myeloid leukemia
plop05223  Non-small cell lung cancer
plop05224  Breast cancer
plop05225  Hepatocellular carcinoma
plop05226  Gastric cancer
plop05230  Central carbon metabolism in cancer
plop05231  Choline metabolism in cancer
plop05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
plop05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:plop00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    125340801 (Mapk3)
   04012 ErbB signaling pathway
    125340801 (Mapk3)
   04014 Ras signaling pathway
    125340801 (Mapk3)
   04015 Rap1 signaling pathway
    125340801 (Mapk3)
   04350 TGF-beta signaling pathway
    125340801 (Mapk3)
   04370 VEGF signaling pathway
    125340801 (Mapk3)
   04371 Apelin signaling pathway
    125340801 (Mapk3)
   04668 TNF signaling pathway
    125340801 (Mapk3)
   04066 HIF-1 signaling pathway
    125340801 (Mapk3)
   04068 FoxO signaling pathway
    125340801 (Mapk3)
   04072 Phospholipase D signaling pathway
    125340801 (Mapk3)
   04071 Sphingolipid signaling pathway
    125340801 (Mapk3)
   04024 cAMP signaling pathway
    125340801 (Mapk3)
   04022 cGMP-PKG signaling pathway
    125340801 (Mapk3)
   04151 PI3K-Akt signaling pathway
    125340801 (Mapk3)
   04150 mTOR signaling pathway
    125340801 (Mapk3)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    125340801 (Mapk3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    125340801 (Mapk3)
   04148 Efferocytosis
    125340801 (Mapk3)
  09143 Cell growth and death
   04114 Oocyte meiosis
    125340801 (Mapk3)
   04210 Apoptosis
    125340801 (Mapk3)
   04218 Cellular senescence
    125340801 (Mapk3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    125340801 (Mapk3)
   04520 Adherens junction
    125340801 (Mapk3)
   04540 Gap junction
    125340801 (Mapk3)
   04550 Signaling pathways regulating pluripotency of stem cells
    125340801 (Mapk3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    125340801 (Mapk3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    125340801 (Mapk3)
   04613 Neutrophil extracellular trap formation
    125340801 (Mapk3)
   04620 Toll-like receptor signaling pathway
    125340801 (Mapk3)
   04621 NOD-like receptor signaling pathway
    125340801 (Mapk3)
   04625 C-type lectin receptor signaling pathway
    125340801 (Mapk3)
   04650 Natural killer cell mediated cytotoxicity
    125340801 (Mapk3)
   04660 T cell receptor signaling pathway
    125340801 (Mapk3)
   04658 Th1 and Th2 cell differentiation
    125340801 (Mapk3)
   04659 Th17 cell differentiation
    125340801 (Mapk3)
   04657 IL-17 signaling pathway
    125340801 (Mapk3)
   04662 B cell receptor signaling pathway
    125340801 (Mapk3)
   04664 Fc epsilon RI signaling pathway
    125340801 (Mapk3)
   04666 Fc gamma R-mediated phagocytosis
    125340801 (Mapk3)
   04062 Chemokine signaling pathway
    125340801 (Mapk3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    125340801 (Mapk3)
   04929 GnRH secretion
    125340801 (Mapk3)
   04912 GnRH signaling pathway
    125340801 (Mapk3)
   04915 Estrogen signaling pathway
    125340801 (Mapk3)
   04914 Progesterone-mediated oocyte maturation
    125340801 (Mapk3)
   04917 Prolactin signaling pathway
    125340801 (Mapk3)
   04921 Oxytocin signaling pathway
    125340801 (Mapk3)
   04926 Relaxin signaling pathway
    125340801 (Mapk3)
   04935 Growth hormone synthesis, secretion and action
    125340801 (Mapk3)
   04919 Thyroid hormone signaling pathway
    125340801 (Mapk3)
   04928 Parathyroid hormone synthesis, secretion and action
    125340801 (Mapk3)
   04916 Melanogenesis
    125340801 (Mapk3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    125340801 (Mapk3)
   04270 Vascular smooth muscle contraction
    125340801 (Mapk3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    125340801 (Mapk3)
  09156 Nervous system
   04724 Glutamatergic synapse
    125340801 (Mapk3)
   04725 Cholinergic synapse
    125340801 (Mapk3)
   04726 Serotonergic synapse
    125340801 (Mapk3)
   04720 Long-term potentiation
    125340801 (Mapk3)
   04730 Long-term depression
    125340801 (Mapk3)
   04723 Retrograde endocannabinoid signaling
    125340801 (Mapk3)
   04722 Neurotrophin signaling pathway
    125340801 (Mapk3)
  09158 Development and regeneration
   04360 Axon guidance
    125340801 (Mapk3)
   04380 Osteoclast differentiation
    125340801 (Mapk3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    125340801 (Mapk3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    125340801 (Mapk3)
   05206 MicroRNAs in cancer
    125340801 (Mapk3)
   05205 Proteoglycans in cancer
    125340801 (Mapk3)
   05207 Chemical carcinogenesis - receptor activation
    125340801 (Mapk3)
   05208 Chemical carcinogenesis - reactive oxygen species
    125340801 (Mapk3)
   05203 Viral carcinogenesis
    125340801 (Mapk3)
   05230 Central carbon metabolism in cancer
    125340801 (Mapk3)
   05231 Choline metabolism in cancer
    125340801 (Mapk3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    125340801 (Mapk3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    125340801 (Mapk3)
   05212 Pancreatic cancer
    125340801 (Mapk3)
   05225 Hepatocellular carcinoma
    125340801 (Mapk3)
   05226 Gastric cancer
    125340801 (Mapk3)
   05214 Glioma
    125340801 (Mapk3)
   05216 Thyroid cancer
    125340801 (Mapk3)
   05221 Acute myeloid leukemia
    125340801 (Mapk3)
   05220 Chronic myeloid leukemia
    125340801 (Mapk3)
   05218 Melanoma
    125340801 (Mapk3)
   05211 Renal cell carcinoma
    125340801 (Mapk3)
   05219 Bladder cancer
    125340801 (Mapk3)
   05215 Prostate cancer
    125340801 (Mapk3)
   05213 Endometrial cancer
    125340801 (Mapk3)
   05224 Breast cancer
    125340801 (Mapk3)
   05223 Non-small cell lung cancer
    125340801 (Mapk3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    125340801 (Mapk3)
   05170 Human immunodeficiency virus 1 infection
    125340801 (Mapk3)
   05161 Hepatitis B
    125340801 (Mapk3)
   05160 Hepatitis C
    125340801 (Mapk3)
   05171 Coronavirus disease - COVID-19
    125340801 (Mapk3)
   05164 Influenza A
    125340801 (Mapk3)
   05163 Human cytomegalovirus infection
    125340801 (Mapk3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    125340801 (Mapk3)
   05165 Human papillomavirus infection
    125340801 (Mapk3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    125340801 (Mapk3)
   05135 Yersinia infection
    125340801 (Mapk3)
   05133 Pertussis
    125340801 (Mapk3)
   05152 Tuberculosis
    125340801 (Mapk3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    125340801 (Mapk3)
   05140 Leishmaniasis
    125340801 (Mapk3)
   05142 Chagas disease
    125340801 (Mapk3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    125340801 (Mapk3)
   05020 Prion disease
    125340801 (Mapk3)
   05022 Pathways of neurodegeneration - multiple diseases
    125340801 (Mapk3)
  09165 Substance dependence
   05034 Alcoholism
    125340801 (Mapk3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    125340801 (Mapk3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    125340801 (Mapk3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    125340801 (Mapk3)
   04934 Cushing syndrome
    125340801 (Mapk3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    125340801 (Mapk3)
   01524 Platinum drug resistance
    125340801 (Mapk3)
   01522 Endocrine resistance
    125340801 (Mapk3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:plop01001]
    125340801 (Mapk3)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:plop03036]
    125340801 (Mapk3)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:plop04147]
    125340801 (Mapk3)
Enzymes [BR:plop01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     125340801 (Mapk3)
Protein kinases [BR:plop01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   125340801 (Mapk3)
Chromosome and associated proteins [BR:plop03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     125340801 (Mapk3)
Exosome [BR:plop04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   125340801 (Mapk3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Haspin_kinase FTA2 Kdo
Other DBs
NCBI-GeneID: 125340801
NCBI-ProteinID: XP_048188595
LinkDB
Position
23:6176782..6184788
AA seq 383 aa
MAAAAAAAAAPGGGGGEPRGADGVGPGVPGEVEVVKGQPFDVGPRYTQLQYIGEGAYGMV
SSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLEAMR
DVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLINT
TCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILA
EMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAKLF
PKSDSKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDDLP
KERLKELIFQETARFQPGGPDAP
NT seq 1152 nt   +upstreamnt  +downstreamnt
atggcggcggcggcggcggcggcggcggctccggggggcgggggcggggagccccgggga
gccgacggggtcggcccgggggtcccgggggaagtggaggtggtgaaggggcagccgttc
gacgtgggcccgcgctacacgcagctgcagtacatcggcgagggggcgtacggcatggtc
agctccgcttatgaccacgtgcgaaagacccgggtggccatcaagaagatcagtcccttt
gagcatcagacctactgccagcgcacactccgggagatccagatcctgctgcgcttccgc
catgagaatgtcataggcatccgagacattctccgggcacctacactggaagccatgagg
gatgtctacattgtacaggacctgatggagacagatctatacaagttgctcaaaagccag
cagctgagcaacgatcacatctgctacttcctgtaccagatcctgcgtggcctcaagtat
atccactcagccaacgtgctgcaccgagacctgaagccctccaacctgctcatcaacacc
acctgcgaccttaagatatgcgatttcggcctggcccgcattgcagatcctgagcacgac
cacacaggctttctgacggagtatgtggccacacgctggtaccgggcccccgagatcatg
cttaactccaagggctataccaagtccatcgacatctggtctgtgggctgcattctggct
gaaatgctctccaaccggcccatcttccctggcaagcactacctggaccagctcaaccac
attctggggattctgggctccccttcccaggaagacctgaattgcatcatcaacatgaaa
gcccgaaactacctacagtctctgccgtccaagaccaaggtggcttgggccaagctcttt
cccaagtcggactctaaagctcttgacctgctggaccggatgttaaccttcaatcccaac
aagcggatcacagtggaggaagcactggcccacccctacctggagcagtactacgatccc
acagatgagccagtggctgaggagcccttcacttttgacatggagctggatgatctaccc
aaggagcggctgaaggagctcatcttccaggagacagcccgcttccagccagggggccca
gatgccccctaa

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