Perognathus longimembris pacificus (Pacific pocket mouse): 125348469
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Entry
125348469 CDS
T08928
Symbol
Dot1l
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
plop
Perognathus longimembris pacificus (Pacific pocket mouse)
Pathway
plop00310
Lysine degradation
plop01100
Metabolic pathways
plop05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
plop00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
125348469 (Dot1l)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
125348469 (Dot1l)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
plop03036
]
125348469 (Dot1l)
Enzymes [BR:
plop01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
125348469 (Dot1l)
Chromosome and associated proteins [BR:
plop03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
125348469 (Dot1l)
HMT complexes
Dot1-containing complex
125348469 (Dot1l)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
125348469
NCBI-ProteinID:
XP_048197654
LinkDB
All DBs
Position
3:complement(64354517..64415599)
Genome browser
AA seq
1743 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNATTPTKVP
ESKAAGPAEATVDSGAEEEKAGVATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSTA
NPERKPKKNQTALDLLNTQTTSQTASPSPQDAYRSPNSPCYQLPPSAQWHSPTPLLVAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLLGHCQAQK
EEIRRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLERDNLELRSQSLQLL
RARCEELKLDWATLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SYVPPDDALSMHLRGKGALGRELEADAGRLHLELDCAKFSLPNFSSMSPELSMNGHTASY
ELCSALSRPSSKQNTPQYLASPLDQEVVPCTPNHSGRPRLEKLSGLALPDYTRLSPAKIV
LRRHLGQDHPAAGKAATSEPHPRAEHAKENSLPYQSPGLSNSMKLSPQDPRPPSPGALPL
AGEKSNEKGVKERSYGSQGETITSLPISIPLSTVQPNKLPVSIPLASVVLPSRAERVRST
PSPVPQPRDSSSTLEKQIGANAHVAGGSTAGSRSLTLASTGFYTGSVAISGALASSPAQL
ASGAESAAFDESSSSGSLFTMVGSRSATPQHPPLLTQPRNSGPTSPIPQLSASPRFSGVT
QGLLPDAGKGDLPSDSGFSDPENEAKRRIVFTISAGTGSTKQSPSTKHSPLAASARGDCG
QSHGQDSRKRGRRKRASAGTPSLSAGVSPKRRALPTVAGLFTQSSGSPLNLNSMVSNINQ
PLEITAISSPENSLKSSPVPYHDHDQPPVLKKERPLSQSNGAHYSPLTSDEEPGSEDEPS
STRIERKIATISLESKSPPKTLDNGGSLVGRKLAPASEPVNSSKWKSTFSPISDISLAKS
TDSPLQASSTLSQNSLFSFRPALEEASAAEAKLTGHQRKSFPSSLLGADGLSPGANPPNG
LAFSGGLAADLSLHGFNDGASLSHKVPEAASLSTPLNFPSQRGKEGTSEANPFLSKRQLD
GLGGLKGENSAGKEVGELGLPLCGPADKAALPHSSRANKGRDRELDFKSGHNLFISAAAV
PPSGLLGGSGLPTAASSAGSTAPTTQTHRPFLSTFTPGPQFTLGPMSLQANLSSVAGSSV
LQSLFSSVPAAAGLVHVSSAATRLTNSHAMGSFSSGVAGGTVGGVFSHTVPSASAHPFGV
SVSSGAVCSSATLGPSPLQAVASTSASSFQAAASVETRPPPPPPPPLLPPQHLGRAPTGP
PVLRAPPPPNVALPPPPALLASNSEPSLLQNLASLPANKAFLPPSSAASLQPANATLSVK
LASLPHKVSHSSFTVHHQPMPRLALAQTAPAVPQASSVGPSAVWVSLGMPPPYAAHLSGV
KPR
NT seq
5232 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgagactcaagtcgcccgtgggggccgagcccgccgtctac
ccctggccgctgccggtctacgacaaacatcacgatgctgctcatgaaatcattgagacc
atacgatgggtctgtgaggaaattcctgacctcaagctggctatggaaaattatgtccta
attgactatgataccaaaagctttgaaagtatgcagcggctatgtgacaagtacaaccgg
gctatcgacagcatccaccagctgtggaagggcactactcaacccatgaagctaaacacg
cgaccatccaatgggctcctacggcacatactgcagcaggtctacaaccactcagtgact
gatcctgagaaacttaacaattatgaacccttctccccggaagtatatggggagacctcc
tttgacctggtggcccagatgattgatgaaatcaagatgactgaggatgatctgtttgtg
gacctgggtagtggtgtgggccaggttgtccttcaggttgctgcagccaccaactgcaaa
catcactatggagtggagaaagctgacatcccagccaagtacgcggagaccatggacaga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaacga
ggcgatttcctctcagaagagtggagagagcggattgccaacacaagtgttatatttgtg
aataactttgcatttggtcctgaggtggatcaccagctgaaggagcgatttgcaaacatg
aaggaaggtggcagaattgtgtcctcaaaaccctttgcacctctgaacttcagaataaac
agcagaaacttgagtgacattggtaccatcatgcgtgtggtagagctgtcgcccctgaag
ggctccgtgtcatggacggggaagccggtctcctactacttacataccattgaccgcacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggaacaagaggca
gctcggcgccgacagcagcgagagaacaagagtaatgccaccacccccaccaaagtccca
gagagcaaagcggctggacccgccgaagccaccgtggattctggtgccgaggaagaaaag
gctggggtggccactgtcaaaaagccatccccctccaaagctcggaaaaagaagttgaac
aagaaagggaggaaaatggctggccggaagcgtggacgtcccaagaaaatgagcactgcg
aaccccgaacgtaagcccaagaagaaccaaactgcactggatctcttgaacactcagacc
acatcccagactgcgtccccctctccccaagatgcttacaggtcacccaacagcccatgc
taccagctacctccaagtgcacagtggcactctcccaccccactgctggtggcacctact
ccgcctgcactgcagaagctgctagagtccttcaagatccagtacctgcagttcctggcc
tacacgaagacgccccagtacaaggccaacctgcaacagctgctggaccaggagaaggag
aagaacacgcagttgctgggcacagcacagcagctcttgggtcactgccaggcccagaaa
gaagagatccggcgactcttccagcagaaactggacgagctgggagtgaaggcgctgacc
tacaacgatctaatccaggctcagaaggagatctctgctcacaaccagcagctgcgggag
cagtcagagcagctggagagagacaaccttgaacttcggagccagagtctgcagctgctc
agggcccggtgtgaggagctaaagctggactgggccacactgtccttggagaaccttcgg
aaagagaagcaggccctgcggagccagatctctgagaagcagcggcactgcctggagctg
cagatcagcatcgtggaattggagaagagccagcggcagcaggagctcctgcagctgaag
tcctacgtgccacctgatgatgccctgtccatgcatttgcgagggaagggtgccctgggc
cgtgagctggaagctgatgctggccggctgcaccttgagctggactgtgccaagttctcc
ctgcctaactttagtagcatgagcccggagctctctatgaatggtcacacggccagttat
gagctctgcagtgctctgagccggccgtcatccaagcagaacaccccccagtacctggct
tctcccttggaccaggaggtcgtgccctgtacccccaaccacagtggtcggccacggctg
gagaagctctctggtctggccttgcctgactatactcggctctcccctgccaagattgta
ctgaggaggcatctgggtcaggaccatcctgcagctggcaaggcagctaccagtgaacca
cacccacgagctgagcatgccaaggaaaacagccttccctaccagagcccgggcttgtca
aacagcatgaagctgagcccccaggacccgaggcctccctcccctggggcattgcccttg
gcaggagaaaagagcaatgagaagggtgtgaaggagcgctcctatggcagccagggggag
accatcactagcctgccgatcagcatcccactcagcacggtgcagcccaacaagctcccc
gtcagcatccctctggccagtgtggtgctgcccagtcgagcagagagggtgaggagcacc
ccaagtcctgtgccgcagcctcgagactcctcatctacacttgagaagcagattggtgct
aatgcccatgttgctgggggcagtactgcagggagcaggagcctcactttggcatccaca
ggcttctataccgggtcggtggccatcagtggggccctggctagcagcccagcacaactg
gcctccggagctgagtcagctgcctttgatgagtcctccagttcggggagcctcttcacc
atggtggggtcccgcagtgcaacaccacagcatcctcctctactgacacagccccggaac
tctggccccacttctccaatcccccagctctctgccagtccccggttcagtggtgtcact
cagggcctgctgcctgatgctggcaagggagacctgccttccgattctggcttctcggac
ccggagaatgaggcaaagaggagaattgtgttcactatctcagctggcacaggcagcacc
aagcagtcaccttccaccaagcatagccccctggcagcaagtgcccgtggggactgtggg
cagagccatgggcaggatagccgaaagcgtggcagaaggaagcgtgcatcagctggaacc
cccagcctgagtgcaggcgtgtcccccaagcgcagggccctgcctactgttgctggcctc
ttcacacagtcctcagggtcccccctcaacctcaactccatggtcagcaacatcaaccag
cccttggaaattacagccatctcatcccccgagaattctctgaagagctcccctgtccct
taccatgaccatgaccagccccctgtgctcaaaaaggaacgaccgctgagccagtccaat
ggggcccactattccccgctgacctcagatgaggaacccggctctgaggatgagcccagc
agtacccgaattgagagaaaaattgcaacaatctccttagaaagcaagtctcccccgaag
accttggataatggtggcagcttggtggggaggaaactggcacctgcaagtgagcccgtc
aacagtagcaagtggaaatctaccttttcacccatctccgacatcagcctggccaagtct
acagacagcccactgcaagctagctccaccctgagccagaactccttgttttcgttccgg
ccagccctggaagaagcctcggcagctgaggccaagctcactggacatcaaaggaaaagc
tttcccagctccctattgggtgctgatggactcagtccaggtgccaacccccccaatggc
ctggccttcagcgggggcctggctgcagacctcagtttacacggcttcaatgacggtgct
tccctttcccacaaagtccctgaggcagccagcctgagcaccccacttaactttccttca
cagcggggcaaggagggcacctcagaggccaacccctttctcagcaagcggcagctggat
ggcctgggcggcctgaagggtgagaacagtgccggcaaggaggtgggcgagctgggcctg
cccctgtgcggtcccgcggacaaagcagctctgccacacagcagcagggctaacaagggc
cgggaccgtgagcttgacttcaagagcggccacaaccttttcatctctgctgcggcggtg
cctcccagtggcctccttggtggctctggcctccccacagcggcctcctctgcaggcagc
acagcccccaccacccagacacaccgccccttcctgagcaccttcacgcccgggccgcag
ttcaccctgggccctatgtccctgcaggccaatctcagctccgtggccggctcgtccgtg
ctgcagtccttgttcagttctgtgccagctgctgcaggcctggtgcatgtgtcatctgct
gcaaccagactgaccaactcccacgccatgggcagcttctcctccggggtggccggtgga
actgtcggaggtgtctttagccacacggtgccctccgcctctgctcatccatttggagtc
agtgtcagcagcggggctgtgtgtagcagtgccacgctgggcccgagcccgctgcaggca
gtggccagcacctcggcctcttcctttcaggccgcggcctccgtggagactcggccgccc
cctccgcccccacctcccctgcttcctcctcagcacctgggccgggcccctacggggccg
cctgtcctccgtgccccccctccacctaatgtcgccttgcctcctccccctgcgctgctg
gcctctaactccgaaccctcgctcctgcagaaccttgcttccctcccagctaacaaagct
ttcttacctccctcctctgccgcctctctgcagcctgctaacgccactctgtctgtcaag
ctcgcctccctcccacacaaggtctcccattcctctttcacggtgcaccaccagcccatg
ccccggctggccctggcacagacagcacccgccgtcccgcaggccagctctgtgggtcca
tctgctgtatgggtttcccttggcatgccgcctccctatgccgcgcacctttcgggggtt
aagccccgataa
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integrated database retrieval system
