Perognathus longimembris pacificus (Pacific pocket mouse): 125348719
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Entry
125348719 CDS
T08928
Symbol
Tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
plop
Perognathus longimembris pacificus (Pacific pocket mouse)
Pathway
plop04217
Necroptosis
plop04380
Osteoclast differentiation
plop04620
Toll-like receptor signaling pathway
plop04621
NOD-like receptor signaling pathway
plop04630
JAK-STAT signaling pathway
plop04658
Th1 and Th2 cell differentiation
plop04659
Th17 cell differentiation
plop05145
Toxoplasmosis
plop05160
Hepatitis C
plop05161
Hepatitis B
plop05162
Measles
plop05164
Influenza A
plop05165
Human papillomavirus infection
plop05167
Kaposi sarcoma-associated herpesvirus infection
plop05168
Herpes simplex virus 1 infection
plop05169
Epstein-Barr virus infection
plop05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
plop00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
125348719 (Tyk2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
125348719 (Tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
125348719 (Tyk2)
04621 NOD-like receptor signaling pathway
125348719 (Tyk2)
04658 Th1 and Th2 cell differentiation
125348719 (Tyk2)
04659 Th17 cell differentiation
125348719 (Tyk2)
09158 Development and regeneration
04380 Osteoclast differentiation
125348719 (Tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
125348719 (Tyk2)
05160 Hepatitis C
125348719 (Tyk2)
05171 Coronavirus disease - COVID-19
125348719 (Tyk2)
05164 Influenza A
125348719 (Tyk2)
05162 Measles
125348719 (Tyk2)
05168 Herpes simplex virus 1 infection
125348719 (Tyk2)
05167 Kaposi sarcoma-associated herpesvirus infection
125348719 (Tyk2)
05169 Epstein-Barr virus infection
125348719 (Tyk2)
05165 Human papillomavirus infection
125348719 (Tyk2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
125348719 (Tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plop01001
]
125348719 (Tyk2)
Enzymes [BR:
plop01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
125348719 (Tyk2)
Protein kinases [BR:
plop01001
]
Non-receptor tyrosine kinases
JAK family [OT]
125348719 (Tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kdo
Kinase-like
ABC1
Motif
Other DBs
NCBI-GeneID:
125348719
NCBI-ProteinID:
XP_048198158
LinkDB
All DBs
Position
3:complement(72198225..72221889)
Genome browser
AA seq
1186 aa
AA seq
DB search
MSLWKPAAVDAPLMADLGGVKVLLHWAGPTGGEPWVTVNDSLLTAEEICVQIAHKIGITP
PCFNLFALFDAQAGVWLPPNHTLDVSRDTNMTLLFRMRFYFRNWHGLNSQEPAVYRCGFP
GAEAPPEQAEQGVQLLDSASFEYLFEQGKHEFVNDIVSLWELTSEEEIHHFKNESLGMAF
LHLCHLSLCRGVPLEDVAKEISFKDCIPRSFRQQIRQHNALTRLRLRNLFRRFVRAFQPR
QLSAHAVMVKYLATLERLAPRFGAERLPARHLQLQAQAPGAPCYTQDGSQASRDSDPESA
LGPPTHEVLVTGTGGIQWRPVQDKVLGSQDSKGGNGDSRNLQGRLSRKKGKAHQAGEQVV
GRPWEPPWTYFCDFQDISHVVLKDSRVSIHRQDNQCLELSLLSRASALSFVALVDGYFRL
TADSSHYLCHEVAPPRLVMSIQDGIHGPLLDPFVRAKLRPEDGLYLIHWSTNHLYRLLLT
VAQRDSAPGVQSLRLRKFPILQEAGTFVMEGWGRSFASIRELRMALQGCALRAGEDCFPL
RRCCLPRPGEISNLLIMRGSRASSQPLHLSQLSFHRIHQDDITQLSHLGQGTRTNVYEGL
LHVGSPEEEEEEEEEDKVDSGISLEPCGSRSRGQELRVVLKVLDPSHHDIAMAFYETASL
MSQVSHAHLAFVHGVCVRGSENIMVTEFVEHGPLDVWLRRERGHVPMTWKVVVAQQLASA
LSYMEDKSLVHGNVCGRNVLLARPGLAEGTSPFIKLSDPGVGLGALSREERVERIPWTAP
ECLTGGASSLSTAADKWGFGATLLEICFDGEAPLQGRGPSEKERFYQKQHQLPEPSCPEL
AMLTSQCLTYEPAQRPSFRTILRDLTRLQPHNLVDISTVNPDSPASDPTVFHKRYLKKIR
DLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKSGCGPQLHSGWRREIDILRTLYHEHIVK
YKGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICQGMAYLHAQHYIH
RDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYA
SDVWSFGVTLYELLTHCDSSQSPPSKFIELIGLTQGQMTVLRLTELLERGERLPRPDKCP
SEVYLLMKNCWEVEASYRPTFQNLIPVLKMAHDKYQAQAPSVFSVC
NT seq
3561 nt
NT seq
+upstream
nt +downstream
nt
atgtctctttggaagccagctgcagtagacgcaccgctcatggccgacttgggaggtgtg
aaggtgctactgcattgggccgggcccacaggtggggagccctgggtcaccgtcaacgat
tccctgctgaccgcggaggagatctgtgttcagatcgcccacaaaattggcatcactcca
ccctgtttcaatctctttgccctcttcgatgcccaggccggagtctggctgcccccaaac
cacaccctggatgtgtccagagacacaaatatgactctgttattccgaatgagattttat
ttccggaactggcatggcttgaattctcaggaacctgctgtgtaccgctgtggattcccg
ggggctgaagcacctccagaacaggcagagcagggggtacaactcttggattcagcctca
tttgagtacctctttgagcagggcaagcatgagtttgtgaatgacatagtctccctgtgg
gagctgacaagtgaagaagagattcaccactttaaaaatgagagcttgggcatggccttt
ctgcacctctgccatctctccctctgccgtggcgttcctctggaggacgtggccaaggag
atcagcttcaaggactgcatcccacgctccttccgccagcagatccgccagcacaatgcg
ctgaccaggctgcgcctgcgcaacctgttccgtcgctttgtgcgcgccttccagccccgc
cagctgtctgcgcacgcggttatggtcaagtacctggccaccctggagcgcctggcaccc
cgcttcggcgccgagcgcctgcctgcccgccacctgcagctgcaggcccaggccccgggg
gcgccctgctacacccaagacggcagccaggcctccagggactcggaccctgagtcagcc
ctgggaccccccacccatgaggtgctggtgactggcacggggggcatccagtggcggcca
gtgcaggacaaggtgctgggctcccaggattccaagggtggcaatggtgacagcaggaac
ctccagggccgcttgtcccggaagaaaggcaaggcccaccaggcaggagagcaggtggtg
ggcaggccctgggagccaccctggacctacttctgcgatttccaagacatttcccatgtg
gtactgaaagacagccgcgtcagcatccaccggcaggacaaccaatgcctggagctgagc
ctactttcccgtgccagcgccttgtcctttgtggctctggtggatggctacttccgcctg
acagcagactccagccactacctgtgccatgaggtggcaccgcctcggctggtgatgagc
atccaggatggcatccacggaccgctgctggatccatttgtgcgagccaagctgcggccg
gaggatgggctgtatctcattcactggagtactaaccacctctaccgcctcctcctcaca
gtggcccagcgtgactcggcacccggggtgcagagcttgcgcctccggaagttccccatc
ctgcaagaggctgggacctttgtgatggagggctggggccgctcctttgccagcatcagg
gagctgcggatggctctgcagggctgtgccctgcgggctggtgaggattgtttcccgctg
cgccgctgctgcctgccccgacctggagaaatctccaacctcctcatcatgcgggggtca
cgggccagcagccagccgcttcatctcagccagctcagcttccacaggatccatcaggat
gacatcacccagctctcccacctgggccagggtacaaggaccaacgtatacgagggcctc
ctacatgtggggagccctgaggaggaggaggaggaggaggaggaagacaaagtggacagt
gggatctccctggagccatgtgggagcaggagccgtgggcaggagctacgggtggtgctt
aaagtactggaccccagtcaccatgacatcgccatggcgttctacgagactgccagcctc
atgagccaggtctcgcatgcacatctggccttcgtgcacggcgtgtgtgtgcgtggctcc
gagaacatcatggtgacagagtttgtggaacatggacccctggacgtgtggctgcggcga
gagcggggtcatgtgcccatgacctggaaggtggtggtggcccagcagctggccagcgcc
ctcagctacatggaagacaagagcctggttcatggtaatgtgtgtggtcgaaacgtcttg
ctagcccggccagggctggcagagggcaccagcccattcatcaagttgagcgatcctggc
gttggcctgggggccctctccagggaagagcgcgttgagcgcatcccctggacggctcct
gagtgcctgactggtggggccagcagcctgagtaccgcggctgacaagtgggggtttggc
gccactctgcttgagatctgctttgatggggaggcccccctccagggccgtggcccatcc
gagaaagagcgtttctaccagaagcagcaccagctgccggagccctcatgccctgagctc
gccatgctcacgagccagtgcctgacctacgagcctgcgcagcggccgtccttccgcacc
atcctgcgcgacctcacacggctgcagcctcacaatctagtggatatctctactgtgaac
cccgactcgcctgcctctgaccccacggttttccacaagcggtatttgaaaaagattcgg
gatctgggcgaggggcactttggcaaggtcagcctgtactgctacgaccccaccaacgat
ggtactggggagatggtggcggtgaaggccctcaagtctggttgcggcccccagctccat
tctggctggaggcgggaaattgacatcctgcgcacactgtaccacgagcacattgtcaag
tacaagggctgctgcgaggaccaaggcgagaagtcggtgcagctggtcatggagtacgtg
cccctgggtagcctccgggactacctgccccggcacagcgtggggctggctcagctgttg
ctcttcgcccagcagatctgccagggcatggcctacctgcacgcccagcactacatccac
cgagatctagccgcgcgcaacgtgctgctggacaacgacaggctggtcaagatcggggac
tttggcctagccaaggccgtgcctgaaggccatgagtactaccgcgtgcgcgaggacggg
gacagccccgtgttctggtatgccccagagtgcttgaaggagtgtaagttctactatgca
tctgatgtctggtcctttggggtgaccctctacgagctgctgacacactgtgactctagc
cagagccccccttcgaaattcatcgagctcataggcctcacccagggccagatgacggtg
ctgagactcaccgagttgctggagcgaggagagaggctgccgaggcccgacaaatgcccc
agtgaggtctatctcctcatgaaaaactgctgggaagtggaggcctcctaccgtcctacc
ttccagaacctcatccccgtcctcaagatggcccacgacaagtaccaggcccaggccccg
tcggtgttcagtgtgtgctga
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