Perognathus longimembris pacificus (Pacific pocket mouse): 125350333
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Entry
125350333 CDS
T08928
Symbol
Atic
Name
(RefSeq) bifunctional purine biosynthesis protein ATIC
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
plop
Perognathus longimembris pacificus (Pacific pocket mouse)
Pathway
plop00230
Purine metabolism
plop00670
One carbon pool by folate
plop01100
Metabolic pathways
plop01523
Antifolate resistance
Module
plop_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
plop00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
125350333 (Atic)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
125350333 (Atic)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
125350333 (Atic)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
plop04147
]
125350333 (Atic)
Enzymes [BR:
plop01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
125350333 (Atic)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
125350333 (Atic)
Exosome [BR:
plop04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
125350333 (Atic)
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SSDB
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Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
125350333
NCBI-ProteinID:
XP_048200773
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Position
4:complement(18197211..18217798)
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AA seq
592 aa
AA seq
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MAPGQLALFSVSDKTGLVEFARNLASLGLNLVASGGTAKALRDAGLAVRDVSDITGFPEM
LGGRVKTLHPAVHAGILARNIPEDNADMSRLDFSLIRVVACNLYPFVKTVASPQVTVEEA
VEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVAVSTEMKSSDSHDTSLETRRQLALKAFT
HTAQYDEAISDYFRRQYSKGISQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINL
CDALNAWQLVKELKEALDIPAAASFKHVSPAGAAVGIPLSQEEAKVCMVYDLYDTLTPVS
TAYARARGADRMSSFGDFIALSDICDVPTAKIISREVSDGIVAPGYEEEALKILSKKKNG
NYCVIQMDQSYKPDENEVRTLFGLRLSQKRNNGVINRSLFNNIVTKNKDLPESAFRDLIV
ATVAIKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKT
GVKRAEISNAIDQYVTGTIGEGEDLVKWKALFEEVPELLTEAEKKEWIDKLTGVSVSSDA
FFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTDLRLFHH
NT seq
1779 nt
NT seq
+upstream
nt +downstream
nt
atggctcccggccagctcgctttatttagtgtctctgacaaaactggccttgtggaattt
gccagaaacctcgcgtctctcggcttgaatctagtagcttccggaggaactgcaaaagct
ctcagggatgctggcttggcagtcagagatgtctctgacataactggatttcctgaaatg
ttagggggccgtgtgaaaaccctgcatcctgcagtccatgctggtattctggctcgtaat
atcccagaagataatgctgacatgtcccgactcgatttcagtcttataagagttgttgct
tgtaatctgtatccctttgtgaagaccgtggcttctccacaggtgactgttgaagaggct
gttgagcaaattgatattggtggagtaaccttgttgagagctgcagccaaaaaccatgct
cgagtaacagtggtgtgtgaaccagaggactatgtggcagtgtccacagagatgaagagc
tctgacagtcacgatacgtccttggagacaaggcgacagttagctttgaaggccttcact
cacacagcacaatatgatgaagcaatttcagattactttaggagacagtacagcaaagga
atatctcagatgcctctgaggtatggaatgaaccctcatcagactcctgcccagctgtac
accctgaagcccaagctccccatcacagttctgaatggagcccctgggtttataaacctg
tgtgatgctctgaatgcctggcagctggtgaaggagctcaaagaagccttagacatccca
gccgcagcctccttcaagcatgtcagcccagcaggtgctgctgttggaattccactcagt
caagaggaggccaaagtctgcatggtctacgacctctatgacaccctgactcctgtgtca
actgcatatgcgagagcaagaggggctgatagaatgtcttcattcggtgacttcattgca
ttatctgatatttgtgatgtccccactgcaaaaattatctcaagagaagtttctgatggt
attgttgccccaggatatgaggaagaagccttaaaaatactttctaaaaagaaaaatgga
aactactgtgttattcagatggaccagtcttacaaaccagacgaaaatgaagttcgaact
ctctttggtcttcgtttaagccagaagagaaacaatggtgtcatcaacaggtcattattc
aacaacatcgttaccaagaataaagatttgccagagtctgccttcagagacctcatcgta
gctactgtcgccatcaagtatacccagtctaactctgtgtgctatgccaagaacgggcag
gttattggcattggagccggacagcagtctcggatacactgcacacgccttgcaggggat
aaggcaaactattggtggcttagacaccatccgcaagtgctttccatgaagtttaaaact
ggggtgaagagagcagaaatctccaatgccattgatcagtatgtgactggcaccattggt
gagggagaagacttggtaaagtggaaggcactgtttgaggaagtccctgagttgttaacg
gaggcagagaaaaaggagtggattgacaaactaactggtgtttctgtcagttccgatgcc
ttcttccctttcagggataatgtagacagagctaagaggagcggtgtggcctacattgcc
gctccctccgggtctgctgctgacaaggttgtgattgaagcttgtgatgaactgggaatc
attttggctcatacagatctccggctcttccaccactga
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