Perognathus longimembris pacificus (Pacific pocket mouse): 125352480
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Entry
125352480 CDS
T08928
Symbol
Gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
plop
Perognathus longimembris pacificus (Pacific pocket mouse)
Pathway
plop00270
Cysteine and methionine metabolism
plop00480
Glutathione metabolism
plop01100
Metabolic pathways
plop01240
Biosynthesis of cofactors
plop04216
Ferroptosis
Module
plop_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
plop00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
125352480 (Gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
125352480 (Gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
125352480 (Gclc)
Enzymes [BR:
plop01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
125352480 (Gclc)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
125352480
NCBI-ProteinID:
XP_048203569
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All DBs
Position
6:2460007..2487858
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AA seq
639 aa
AA seq
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MGLLAQGSPLSWEDTKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKVQLVLSGEDVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRQEATSVLGENQALCTITSFPRLGCPGFTLPEYKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFVETFPDEEAAQAAQPDHIYMDAM
GFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVIS
ASVDDRTREERGLEPLKTSNYRISKSRYDSIDSYLSKCGEKYNDLDLTIDKEIYGQLLQE
GIDHLLAQHVAHLFIRDPLTLFEEKIHMDDANESDHFENIQSTNWQTMRFKPPPPNSDIG
WRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKTAQRRDAVLQ
GLFYFRKDICKGGHAVVDGCGKTPSSAELAAEEYGLMSIDTIINGKEGVFPGLIPILNSY
LENMEVDVDTRCSILNYLKLIKKRASGQLMTVARWMREFIANHPDYKQDSVITDEVNYSL
MVKCNQIASEQCECPELLGSAFRRRAKDGGSTADSGPSK
NT seq
1920 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctggcccaggggtcgccgctcagctgggaggacaccaagcgccacgccgac
cacgtgcggcggcacgggatcctgcagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgtgctcaagtggggcgacgaggtggaatacatgttggtatcttttgatcat
gaaaataaaaaagtccagttggtcctgtctggagaagatgttcttgaaactctgcaagag
aaaggggaaaggacaaaccccaatcaccctaccctctggaggcccgagtacggaagctac
atgatcgaggggaccccaggacagccctacggggggaccatgtccgaattcaacacagtc
caggacaacatgcggaagcggcggcaggaggcgacctcggtgctgggagagaaccaggcc
ctgtgcaccatcacgtccttccccagattaggctgtcctgggttcacactgcctgagtac
aaacccaaccctgtggaaggaggcgcctccaagtccctcttcttcccagatgaagcaata
aacaagcacccccgcttcagtaccctaacaagaaatatccggcataggagaggagaaaag
gttgtcatcaatgtgccaatatttaaggacaagaacacgccgtctccatttgtggagacg
tttcctgacgaggaggcggcccaggcagcccagcccgaccacatctacatggacgccatg
gggtttgggatgggcaactgctgccttcaggtgacattccaagcctgcagcatatctgaa
gccagatacctttatgatcagttggccactatctgcccgattgtcatggcattgagtgcc
gcgtctccattttaccggggctacgtgtccgacatcgactgccgctggggggtcatctct
gcttctgtggacgaccggaccagggaggagcgaggactggagccactgaagaccagtaac
tacaggatcagcaagtcacggtacgattccatagacagctacttgtctaagtgtggggag
aaatacaatgaccttgacttgaccatcgacaaggagatctacgggcagctcctccaggaa
ggcattgatcacctcctggcccagcacgtcgctcatctctttatcagagacccactgacc
ctgtttgaagagaaaatacacatggacgatgccaacgagtctgaccactttgagaatatt
cagtccacaaattggcagacaatgaggtttaagccgcctcctccaaactcagacatcggc
tggagagtggaattccggcccatggaggtgcagttgacagactttgagaactccgcgtac
gtggtgtttgtggtgctgctcaccagggtgatcctgtcctacaaactagacttcctcatc
cccctgtcgaaggttgacgagaacatgaagacagcgcagagacgcgatgccgtgttgcag
ggcttgttctacttcaggaaggacatctgcaaaggcggccacgcggtggtggacggctgc
ggcaagaccccgagcagcgcggagctggccgccgaggagtacggcctcatgagcatcgac
accatcatcaacggcaaggaaggcgtgttccccggcctcatccccatcctcaactcctac
ctggagaacatggaggtggacgtggacaccaggtgcagcatcctcaactacctgaagctc
atcaagaagagagcgtccggacaactgatgactgtcgcccgatggatgagggagttcatc
gcgaaccatcctgactacaagcaggacagcgtcataacggacgaggtgaactacagtctc
atggtgaaatgtaaccaaattgccagcgaacagtgcgaatgcccagagttgctgggctcg
gctttccggaggcgggcgaaggatggggggagcacagccgactctggcccctccaagtag
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