Perognathus longimembris pacificus (Pacific pocket mouse): 125363420
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Entry
125363420 CDS
T08928
Symbol
Sos2
Name
(RefSeq) son of sevenless homolog 2 isoform X1
KO
K03099
son of sevenless
Organism
plop
Perognathus longimembris pacificus (Pacific pocket mouse)
Pathway
plop01521
EGFR tyrosine kinase inhibitor resistance
plop01522
Endocrine resistance
plop04010
MAPK signaling pathway
plop04012
ErbB signaling pathway
plop04014
Ras signaling pathway
plop04062
Chemokine signaling pathway
plop04068
FoxO signaling pathway
plop04072
Phospholipase D signaling pathway
plop04150
mTOR signaling pathway
plop04151
PI3K-Akt signaling pathway
plop04510
Focal adhesion
plop04540
Gap junction
plop04630
JAK-STAT signaling pathway
plop04650
Natural killer cell mediated cytotoxicity
plop04660
T cell receptor signaling pathway
plop04662
B cell receptor signaling pathway
plop04664
Fc epsilon RI signaling pathway
plop04714
Thermogenesis
plop04722
Neurotrophin signaling pathway
plop04810
Regulation of actin cytoskeleton
plop04910
Insulin signaling pathway
plop04912
GnRH signaling pathway
plop04915
Estrogen signaling pathway
plop04917
Prolactin signaling pathway
plop04926
Relaxin signaling pathway
plop04935
Growth hormone synthesis, secretion and action
plop05034
Alcoholism
plop05160
Hepatitis C
plop05161
Hepatitis B
plop05163
Human cytomegalovirus infection
plop05165
Human papillomavirus infection
plop05200
Pathways in cancer
plop05205
Proteoglycans in cancer
plop05206
MicroRNAs in cancer
plop05207
Chemical carcinogenesis - receptor activation
plop05208
Chemical carcinogenesis - reactive oxygen species
plop05210
Colorectal cancer
plop05211
Renal cell carcinoma
plop05213
Endometrial cancer
plop05214
Glioma
plop05215
Prostate cancer
plop05220
Chronic myeloid leukemia
plop05221
Acute myeloid leukemia
plop05223
Non-small cell lung cancer
plop05224
Breast cancer
plop05225
Hepatocellular carcinoma
plop05226
Gastric cancer
plop05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
plop00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
125363420 (Sos2)
04012 ErbB signaling pathway
125363420 (Sos2)
04014 Ras signaling pathway
125363420 (Sos2)
04630 JAK-STAT signaling pathway
125363420 (Sos2)
04068 FoxO signaling pathway
125363420 (Sos2)
04072 Phospholipase D signaling pathway
125363420 (Sos2)
04151 PI3K-Akt signaling pathway
125363420 (Sos2)
04150 mTOR signaling pathway
125363420 (Sos2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
125363420 (Sos2)
04540 Gap junction
125363420 (Sos2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
125363420 (Sos2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
125363420 (Sos2)
04660 T cell receptor signaling pathway
125363420 (Sos2)
04662 B cell receptor signaling pathway
125363420 (Sos2)
04664 Fc epsilon RI signaling pathway
125363420 (Sos2)
04062 Chemokine signaling pathway
125363420 (Sos2)
09152 Endocrine system
04910 Insulin signaling pathway
125363420 (Sos2)
04912 GnRH signaling pathway
125363420 (Sos2)
04915 Estrogen signaling pathway
125363420 (Sos2)
04917 Prolactin signaling pathway
125363420 (Sos2)
04926 Relaxin signaling pathway
125363420 (Sos2)
04935 Growth hormone synthesis, secretion and action
125363420 (Sos2)
09156 Nervous system
04722 Neurotrophin signaling pathway
125363420 (Sos2)
09159 Environmental adaptation
04714 Thermogenesis
125363420 (Sos2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
125363420 (Sos2)
05206 MicroRNAs in cancer
125363420 (Sos2)
05205 Proteoglycans in cancer
125363420 (Sos2)
05207 Chemical carcinogenesis - receptor activation
125363420 (Sos2)
05208 Chemical carcinogenesis - reactive oxygen species
125363420 (Sos2)
05231 Choline metabolism in cancer
125363420 (Sos2)
09162 Cancer: specific types
05210 Colorectal cancer
125363420 (Sos2)
05225 Hepatocellular carcinoma
125363420 (Sos2)
05226 Gastric cancer
125363420 (Sos2)
05214 Glioma
125363420 (Sos2)
05221 Acute myeloid leukemia
125363420 (Sos2)
05220 Chronic myeloid leukemia
125363420 (Sos2)
05211 Renal cell carcinoma
125363420 (Sos2)
05215 Prostate cancer
125363420 (Sos2)
05213 Endometrial cancer
125363420 (Sos2)
05224 Breast cancer
125363420 (Sos2)
05223 Non-small cell lung cancer
125363420 (Sos2)
09172 Infectious disease: viral
05161 Hepatitis B
125363420 (Sos2)
05160 Hepatitis C
125363420 (Sos2)
05163 Human cytomegalovirus infection
125363420 (Sos2)
05165 Human papillomavirus infection
125363420 (Sos2)
09165 Substance dependence
05034 Alcoholism
125363420 (Sos2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
125363420 (Sos2)
01522 Endocrine resistance
125363420 (Sos2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
RHG20_PH
IQ_SEC7_PH
Motif
Other DBs
NCBI-GeneID:
125363420
NCBI-ProteinID:
XP_048218573
LinkDB
All DBs
Position
14:complement(21057474..21128309)
Genome browser
AA seq
1332 aa
AA seq
DB search
MQQAPQPYDFFSEENSPKWRGLLVPALRKVQEQVHPNLSANEESLYYIEELIFQLLNKLC
MAQPRTVQDVEERVQKTFPHPIDKWAIADAQSAIEKRKRRNPLLLPVDKIHPSLKEVLGY
KVDYHVSLYIVAVLEYISADILKLAGNYVFNIRHYEISQQDIKVSMCADKVLMDMFDQDD
IGLVSLCEDEPSSSGELNYYDLVRTEIAEERQYLRELNMIIKVFREAFLSDRNLFKPSDI
EKIFSNILDIHELTVKLLGLIEDTVEMTDESSPHPLAGSCFEDLAEEQAFDPYETLSQDI
LSPEFNEHFSKLMAKPAVALYFQSIADGFKEAVRYVLPRLMLVPVYHCWHYFELLKQLKA
CSEEQEDRECLNQAITALMNLQGSMDRIYKQYSPRRRPGDPVCPFYNRQLRSKHLAIKKM
NEIQKNIDGWEGKDIGQCCNEFIMEGPLTRVGAKHERHIFLFDGLMISCKPNHCQTRLPG
YSSAEYRLKEKFVMRKTQICDKEDTCECKHAFELVSKDENSIIFAAKSAEEKNNWMAALI
SLHYRSTLDRMLDSVLLKEENEQPLRLPSPEVYRFVVKDSEENIVFEDNLQSRSGIPIIK
GGTVVKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLNLLIERFEIPEPEPTEADKLA
IEKGEQPISADLKRFRKEYVQPVQLRVLNVFRHWVEHHFYDFERDLELLERLESFILSVR
GKAMKKWVESIAKIIKRKKQAQANGISHNITFESPPPPIEWHISRPGQFESFELMTLHPI
EIARQLTLLESDLYRKVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIVEA
ENFEERVAVLSRIIEILQVFQDLNNFNGVLEIVSAVNSVSVYRLDHTFEALQERKRKILD
EAMELSQDHFKKYLVKLKSINPPCVPFFGIYLTNILKTEEGNNDFLKKKGKDLINFSKRR
KVAEITGEIQQYQNQPYCLRIEPEMRRFFENLNPMGSLSEKEFTDYLFNTSLEIEPRSCK
QPTRFPRKSTFSLKSPGIRPNTGRHGSTSGTLRGHPTPLEREPYKISFSRIAETELESTV
SAPTSPNTPSTPPVSASSDLSVFLDVDLNSSCGSNSIFAPVLLPHSKSFFSSCGSLHKLS
EEPLIPPPLPPRKKFDHDSSNSKGTIKPDDDPPAIPPRQPPPPKVKPRVPVPTGAFDGQL
HSPPPPPPRDPLPDTPPPVPLRPPEHFVNCPFNLQPPPLGHLHRDSEWFRDVSTCPNSPS
TPPSTPSPRVPRRCYGLSSSNNNLVHPPAPPVPPRQNSSPHLPKLPPKTYKRELSHPPLY
RLPFLENAESPQ
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atgcagcaggcgccgcagccctacgacttcttcagcgaagagaacagcccgaaatggcgg
ggactcctggtcccagccctgcggaaggttcaggaacaagtacatcccaatctctcagct
aatgaagagtctctctactacattgaagagcttatttttcagctgcttaataaattatgc
atggcccaaccaaggactgttcaagatgtggaggaacgagtccaaaagaccttccctcat
ccaattgataagtgggctattgctgatgcacaatctgccatagagaaaagaaaacgaaga
aatcctcttttactgcctgtagacaaaatccatccttcattgaaggaagttttggggtat
aaagtggactatcatgtgtccctatatattgtggctgtactagagtatatctcagcagac
attttgaaattggctggtaattatgtttttaatatccgacattatgaaatatctcaacag
gacattaaagtgtcaatgtgtgcagataaggtcttgatggatatgtttgaccaggatgac
ataggtttggtttctctgtgtgaagatgaacctagttcttcaggtgaattaaactactat
gaccttgtgaggactgaaattgcagaagaaagacagtatctacgggagttaaatatgatc
ataaaagtatttcgagaggcctttctatctgacagaaacttgtttaagccttctgatatt
gaaaagattttcagtaacattttagatatacatgaactgacagtgaaacttttaggtttg
attgaagacacagttgaaatgactgatgaaagtagtcctcatcccttagctggcagctgt
tttgaagatttagcagaggaacaagcatttgatccatatgagacattatcacaggacatt
ctttcacctgagtttaatgagcacttcagtaaattgatggctaagcctgcagttgcttta
tactttcagtccattgctgatggctttaaggaggcagttcgttacgttcttccacgactt
atgttggtgccagtgtatcattgttggcattattttgaattgctcaagcaattgaaagca
tgtagtgaagagcaagaagacagagaatgtttgaatcaagctattacagctctcatgaat
ctccagggtagtatggaccgaatttacaagcagtattcacctagacgccgacctggggat
cctgtttgccctttttataatcgtcaattaagaagcaagcatctagctatcaaaaagatg
aatgagattcagaaaaacattgatggatgggaaggcaaagatattggacagtgttgtaat
gaatttataatggaaggaccgttgacaagagttggtgctaaacatgaaaggcacattttc
ctctttgatggcttaatgatcagctgtaaacctaatcattgccaaacccggcttccagga
tacagtagtgcggaatacagattaaaagaaaagtttgtcatgaggaaaacacaaatctgt
gataaagaagatacttgtgagtgcaaacatgcttttgaattagtatccaaagatgaaaac
agcataatatttgctgctaagtctgctgaagaaaaaaataattggatggcagcccttata
tctcttcattatcgtagtactctagatcgaatgcttgattcagtattattgaaagaagaa
aatgagcaaccactaagattaccaagcccagaagtgtatcgttttgtggtaaaagactca
gaggaaaacattgtttttgaagacaacttgcaaagtagaagtggaatccccattattaaa
ggaggaactgtggtgaaattaattgaaaggttaacatatcatatgtatgctgatcccaat
tttgttcggacttttcttactacgtatcgttcattttgtaaaccacaggagttgctaaat
ttgctgattgaacgatttgagattccagagccagaacctactgaagcagacaaactggca
atagagaaaggcgagcagccaatcagtgcagaccttaaaagatttcgcaaggaatatgtt
caaccagtacaacttagggtcttaaatgtgtttcggcactgggttgagcaccatttttat
gactttgaaagagatttggaattgcttgaaagactagaatctttcattttaagtgtaaga
ggaaaagctatgaagaaatgggtagagtcaatcgcaaagatcatcaagagaaagaagcaa
gctcaggcaaatggaataagccataatatcacctttgaaagtccacccccaccaattgaa
tggcatatcagtagaccaggacaatttgaatcatttgagcttatgacacttcacccaata
gaaattgcacgtcaacttacacttttagagtccgatctctacaggaaagttcaaccttct
gaacttgttggaagtgtgtggaccaaagaagacaaagaaataaattccccaaatttatta
aaaatgattcgccatacaacaaatctcacactgtggtttgaaaaatgcattgtggaagca
gaaaattttgaagaacgggtggcagtactaagtagaattatagaaattctgcaagttttt
caagatttgaacaatttcaatggtgtattggagatagtcagtgcggtaaattcagtgtca
gtatacagattagaccatacctttgaggcattacaggaaagaaagaggaaaattttggat
gaagctatggaattaagccaggatcactttaaaaaatacctagtaaagcttaagtcaatc
aatccaccttgtgtgcctttttttggaatatatttaacaaatattctgaagacggaagag
ggaaataatgattttctaaaaaagaaagggaaagatttaatcaatttcagtaagaggagg
aaagtagctgaaattactggagaaattcagcaatatcagaatcagccttattgtttacgg
atagaaccagaaatgaggagattctttgaaaaccttaaccccatgggaagtttatctgaa
aaagaatttacagactatttgttcaatacgtcactagaaattgaaccccgaagttgcaaa
cagccaactcgatttcctaggaaatcaaccttctccttaaaatctcctggaataaggcct
aatacaggtcgacatggctctacctcaggcactttacgaggtcatccaacaccattagaa
agagaaccatataagataagctttagtcggattgctgaaactgagcttgaatcaacagtg
tcagcaccaacatctccaaatacgccatctactccaccagtgtctgcttcttcagacctg
agtgtgtttttagatgtggatctcaatagttcatgtggcagcaatagcatctttgctcca
gtgctcttgccacactcaaagtctttcttcagttcatgtggtagtttacacaaactaagt
gaagaaccacttattcctcctcctctgcctcctcgaaaaaagtttgatcatgattcttca
aactccaagggaactataaaacctgatgacgaccctcctgctatcccaccaagacagcct
ccccctccaaaggtaaaacccagagttcctgttcctactggtgcatttgatggacagctg
catagtccgcctccaccaccgccaagagaccctcttcctgacactcctccacctgttccc
cttcggcctccagaacactttgtaaactgcccatttaatcttcagccacctccactggga
catcttcacagagactcagaatggttcagagatgttagtacatgtccaaattcgccaagc
actcctcctagcacaccctctccaagagtaccgcgccgatgctatgggctcagttctagt
aacaacaatcttgttcatcctccagctccccccgttccaccaaggcagaattcaagccct
cacctaccaaaactgccaccaaagacttacaagcgggaactttcacatcccccgttgtat
agactgccttttctagaaaatgcagaaagtcctcaatga
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