Perognathus longimembris pacificus (Pacific pocket mouse): 125365151
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Entry
125365151 CDS
T08928
Symbol
Nf1
Name
(RefSeq) neurofibromin isoform X1
KO
K08052
neurofibromin 1
Organism
plop
Perognathus longimembris pacificus (Pacific pocket mouse)
Pathway
plop01521
EGFR tyrosine kinase inhibitor resistance
plop04010
MAPK signaling pathway
plop04014
Ras signaling pathway
Brite
KEGG Orthology (KO) [BR:
plop00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
125365151 (Nf1)
04014 Ras signaling pathway
125365151 (Nf1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
125365151 (Nf1)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PH_NF1
RasGAP
CRAL_TRIO_2
CRAL_TRIO
MIF4G_like_2
Motif
Other DBs
NCBI-GeneID:
125365151
NCBI-ProteinID:
XP_048220995
LinkDB
All DBs
Position
17:20633232..20890082
Genome browser
AA seq
2842 aa
AA seq
DB search
MAAHRPVEWVQAVVSRFDEQLPIKTGQQNTHTKVSTEHNKECLINISKYKFSLVISGLTT
ILKNVNTMRIFGEAAEKNLYLSQLIILDTLEKCLAGQPKDTMRLDETMLVKQLLPEICHF
LHTCREGNQHAAELRNSASGVLFSLSCNNFNAVFSRISTRLQELTVCSEDNVDVHDIELL
QYINVDCAKLKRLLKETAFKFKALKKVAQLAVINSLEKAFWNWVENYPDEFTKLYQIPQT
DMAECAEKLFDLVDGFAESTKRKAAVWPLQIILLILCPEIIQDISKDVVDENNMNKKLFL
DSLRKALAGHGGSRQLTESAAIACVKLCKASTYINWEDNSVIFLLVQSMVVDLKNLLFNP
SKPFSRGSQPADVDLMIDCLVSCFRISPHNNQHFKICLAQNSPSTFHYVLVNSLHRIITN
SALDWWPKIDAVYCHSVELRNMFGETLHKAVQACGAHPAIRMAPSLTFKEKVTSLKFKEK
PTDLETRNYKFLLLSMVKLIHADPKLLLCNPRKQGPETQGSTAELITGLVQLVPQSHMPE
VAQEAMEALLVLHQLDSIDLWNPDAPVETFWEISSQMLFYICKKLTSHQMLSSTEILKWL
REILICRNKFLLKNKQADRSSCHFVFLYGVGCDGPASGNATQMSMDHEELLRTYTPGASL
RKGKGNSSMDSTTGCSGTPPICRQAQTKLEVALYMFLWSPDTEAVLVAMSCFRHLCEEAD
IRCGVDEVSVHNFLPNYNTFMEFASVSNMMSTGRAALQKRVMALLRRIEYPTAGNTEAWE
DTHAKWEQATKLILNYPKAKMEDGQAAESLHKTIVKRRMSHVSGGGSIDLSDTDSLQEWI
NMTGFLCALGGVCLQQRSNCGLATYSPPMGPVSERKGSMISVMSSDGNTDTPVSKFMDRL
LSLMVCNHEKVGLQIRTNVKDLVGLELSPALYPMLFNKLKNTISKFFDSQGQVLLTDTNT
QFVEQTIAIMKNLLDNHTEGSSEHLGQASIETMMLNLVRYVRVLGNMVHAIQIKTKLCQL
VEVMMARRDDLSFCQEMKFRNKMVEYLTDWVMGTSNQAADDDVKCLTRDLDQASMEAVVS
LLAGLPLQPEEGDGVELMEAKSQLFLKYFTLFMNLLNDCSEVEDENAQTGGRKRGMSRRL
ASLRHCTVLAMSNLLNANVDSGLMHSIGLGYHKDLQTRATFMEVLTKILQQGTEFDTLAE
TVLADRFERLVELVTMMGDQGELPIAMALANVVPYSQWDELARVLVTLFDSRHLLYQLLW
NMFSKEVELADSMQTLFRGNSLASKIMTFCFKVYGATYLQKLLDPLLRIVITSSDWQHVS
FEVDPTRLEPSESLEENQRNLLQMTEKFFHAIISSSSEFPPQLRSVCHCLYQATCHSLLN
KATVKEKKENKKSVVSQRFPQNSIGAVGSAMFLRFINPAIVSPYEAGILDKKPPPRIERG
LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDLARRFFLDMASDCPTSDAVNHSLSF
ISDGNVLALHRLLWNNQEKIGQYLSSNRDHKAVGRRPFDKMATLLAYLGPPEHKPVADTH
WSSLNLTSSKFEEFMTRHQVHEKEEFKALKTLSIFYQAGTSKAGNPIFYYVARRFKTGQI
NGDLLIYHVLLTLKPYYAKPYEIVVDLTHTGPSNRFKTDFLSKWFVVFPGFAYDNVSAVY
IYNCNSWVREYTKYHERLLTGLKGSKRLIFIDCPGKLAEHIEHEQQKLPAATLALEEDLK
VFHNALKLAHKDTKVSIKVGSTAVQVTSAERTKVLGQSVFLNDIYYASEIEEICLVDENQ
FTLTIANQGTPLTFMHQECDAIVQSIIHIRTRWELSQPDSIPQHTKIRPKDVPGTLLNIA
LLNLGSSDPSLRSAAYNLLCALTCTFNLKIEGQLLETSGLCIPANNTLFIVSISKTLAAN
EPHLTLEFLEECISGFSKSSIELKHLCLEYMTPWLSNLVRFCKHNDDAKRQRVTAILDKL
ITMTINEKQMYPSIQAKIWGSLGQITDLLDVVLDSFIKTSATGGLGSIKAEVMADTAVAL
ASGNVKLVSSKVIGRMCKIIDKTCLSPTPTLEQHLMWDDIAILARYMLMLSFNNSLDVAA
HLPYLFHVVTFLVATGPLSLRASTHGLVINIIHSLCTCSQLHFSEETKQVLRLSLTEFSL
PKFYLLFGISKVKSAAVIAFRSSYRDRSFSPGSYERETFALTSLETVTEALLEIMEACMR
DIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRILSKALESC
LKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWVAVAVLQLDEVNLYSAGTALL
EQNLHTLDSLRIFNDKSPEEVFMATRNPLEWHCKQMDHFVGLNFNSNFNFALVGHLLKGY
RHPSPAIVARTVRILHTLLTLVNKHRNCDKFEVNTQSVAYLAALLTVSEEVRSRCSLKHR
KSLLLTDISMENVPMDTYPLHHGDPSYRTLKENQPWSSPKGSEGYLAATYPTVGQTSPRA
RKSMSLDMGQPSQANTKKLLGTRKSFDHLISDTKAPKRQEMESGITTPPKMRRVAETDYE
MAETQRIPSSQQHPHLRKVSVSESNVLLDEEVLTDPKIQALLLTVLATLVKYTTDEFDQR
ILYEYLAEASVVFPKVFPVVHNLLDSKINTLLSLCQDPNLLNPIHGIVQSVVYHEESPPQ
YQTSYLQSFGFNGLWRFAGPFSKQTQIPDYAELIVKFLDALIDTYLPGIDEETSEESLLT
PTSPYPPALQSQLSIAANLNLSNSMTSLATSQHSPGIDKENVELSPTSGHCNSGRTRHGS
ASQVQKQRSAGSFKRNSIKKMM
NT seq
8529 nt
NT seq
+upstream
nt +downstream
nt
atggccgcgcacaggccggtggaatgggtccaggccgtggttagccgcttcgacgagcag
ctcccaataaaaacaggacaacagaacacacataccaaagtcagcactgagcacaataag
gaatgtctaatcaatatttccaaatacaagttttccttggttataagtggtctcactact
atcttaaagaatgttaacaccatgaggatatttggagaagctgctgaaaaaaatttgtat
ctctctcagttaattatattggatacactggaaaaatgtcttgctgggcaaccaaaagac
acaatgagattagatgaaaccatgttggtcaagcagttgctgccagaaatctgccatttt
cttcacacctgtcgagaaggaaaccagcatgcagctgaacttcggaattctgcctctggg
gttttattttctctcagctgcaacaacttcaatgcagtcttcagtcgcatttctaccagg
ttacaggaattgactgtttgttcagaagacaatgttgatgtccatgatatagaattgttg
cagtatattaatgtggattgtgcaaaactgaaacgacttttgaaggaaacagcgtttaaa
tttaaagccctaaagaaggttgcacagttagctgttataaacagcctggaaaaggccttt
tggaactgggtagaaaattatccagatgaatttacaaagctctaccagattccacagact
gatatggctgagtgtgcagaaaagctgtttgacttggtggatggttttgctgagagcacc
aaacgtaaagcagcagtttggccactacaaatcattctccttattttgtgtcccgaaata
atccaggatatatccaaggatgtggttgatgaaaacaatatgaataagaagttgtttctg
gacagtctacgaaaagcacttgctggccatggaggaagcaggcaactgacagaaagtgct
gccattgcttgtgtcaaattgtgtaaagcaagtacttatatcaattgggaagacaactct
gtcatttttctactagttcaatccatggtggttgatcttaagaacctgctttttaatcca
agtaaaccattctcaagaggcagtcagcctgcagatgtggatctaatgattgattgcctt
gtttcttgctttcgtataagtcctcacaacaaccagcacttcaagatctgcttggctcag
aattcaccttctacatttcactatgtgttggtaaattcactccatcgtatcatcaccaat
tctgcattggattggtggcccaagattgatgctgtatattgccactcagttgaacttcga
aatatgtttggtgaaacacttcataaagcagtgcaggcttgtggggcacacccagcaata
cgaatggcaccgagtcttacatttaaagaaaaagttacaagccttaaattcaaagaaaaa
cctacagaccttgagacaagaaactataaatttcttctcttgtccatggtgaaactaatt
catgcagatccaaagcttttgctttgtaatccaagaaaacagggtcctgaaactcaaggc
agtacagcagaattaattacagggcttgtacagctggtccctcaatcacacatgccagag
gttgctcaggaagcaatggaggctttgctggttcttcatcaattagacagcattgattta
tggaatcctgatgcgcctgtagaaacattttgggagattagttcacaaatgctattttat
atctgcaagaaattaactagccatcaaatgcttagtagcacagaaattctcaagtggtta
cgggaaattttgatctgcaggaataaatttcttcttaaaaacaagcaggcagatagaagt
tcctgtcactttgtcttcctttatggagtaggatgtgatggtcctgctagtggaaatgcc
actcagatgtccatggatcatgaagaattactgcgtacctatactcctggagcatctctg
cggaagggaaaaggaaattcttccatggatagtacaacagggtgcagtggaaccccaccg
atatgccgacaagcccaaaccaagctagaagtggccctgtacatgtttctatggagccct
gacactgaagctgttctggttgccatgtcctgtttccgccacctctgtgaggaagcggat
attcggtgtggggtagatgaagtgtcagtgcacaatttcttgcccaactataacacattc
atggaatttgcatctgtcagcaacatgatgtcaacaggaagagcagcacttcagaaaaga
gtaatggctctgctaaggcgcattgagtaccctactgcaggaaacactgaggcttgggaa
gatacacatgcaaaatgggagcaagctacaaaactaattcttaattatccgaaagccaaa
atggaggatggccaggctgctgaaagccttcacaagaccattgttaagagacggatgtct
catgtgagtggaggaggatccatagatttgtctgatacagattccctacaggaatggatc
aacatgactggcttcctttgtgcccttgggggagtatgcctacagcagagaagtaactgt
ggtctggcaacttatagcccacccatgggccccgtcagtgaacgtaaagggtccatgatt
tcagtgatgtcctcagatggaaacacagatacacctgtcagcaaatttatggaccggctg
ttgtctttaatggtgtgtaaccatgagaaggtgggacttcaaatacggaccaatgttaag
gatctcgtgggtctagaattgagtcctgctctctatccaatgctgtttaacaaactgaag
aataccatcagcaaattttttgattcccaaggacaggttttattgactgataccaatact
caatttgtagagcaaaccatagctataatgaagaacttactagataatcatactgaaggc
agctctgaacatttgggacaagctagcattgaaacaatgatgttaaatctggtcagatac
gttcgtgtgcttgggaacatggttcatgcaattcagataaaaacgaaactgtgtcaatta
gttgaagtaatgatggcaaggagggatgatctctcattttgtcaagagatgaaatttagg
aataagatggtagaatatctgacagactgggtcatggggacctcaaaccaagcagcagat
gatgatgtaaaatgtcttacaagagatttggaccaagcaagcatggaagcagtagtttca
ctcctcgctggtcttccgctgcaacccgaggaaggagatggtgtggaattaatggaagcc
aaatcacagttatttcttaagtacttcacattatttatgaaccttttgaatgactgcagt
gaagttgaagatgaaaatgcacaaacaggtggcaggaaacgtggtatgtctcggagactg
gcatccctaaggcattgtacagtccttgcaatgtcaaatttactcaatgctaatgtggac
agtggactcatgcactccataggtttaggttatcacaaggatctccagacaagagctaca
tttatggaagttctcacaaaaatccttcaacaaggaacagaatttgacacccttgcagaa
acagtgttggcggatcggtttgagagacttgtggaattggtcacaatgatgggagatcaa
ggagagctccctatagctatggctctggccaatgtggtcccttattctcagtgggatgaa
ctagctcgagttctagttactctatttgattctcgacatttactctaccaactgctctgg
aacatgttttctaaggaagtagaattggcagactctatgcagactcttttccgaggcaac
agcttggccagtaaaataatgacattttgttttaaggtatatggtgctacttatctgcaa
aaactcctggatcctttattaagaattgttatcacatcctctgattggcaacatgttagc
tttgaagtggatcctaccaggttagaaccttcagagagcctggaggaaaaccagcggaac
ctcctgcagatgactgaaaagttctttcatgccatcatcagctcctcctcagaatttccc
cctcagctcagaagtgtgtgccactgtttatatcaggcaacttgccactccctactgaat
aaagctacagtaaaagaaaaaaaggaaaacaaaaaatcagtggttagccaacgtttccct
cagaacagcatcggtgcagtaggaagtgccatgttcctcagatttatcaatcctgccatt
gtctcaccatatgaagcagggattttagataaaaaaccaccacctagaattgaaaggggc
ttgaagctgatgtcaaagatacttcagagtattgccaatcatgttctcttcactaaagaa
gaacatatgcggccttttaatgattttgtgaaaagcaactttgatttggcacgaaggttt
ttccttgatatggcatcagattgtcccacaagtgatgcagtaaaccatagtctttccttc
atcagtgatggcaatgtgcttgctttacatcgtctgctttggaacaaccaagaaaaaatt
ggtcaatacctttccagcaacagggatcataaagctgttggaagacgaccttttgataag
atggcaacacttcttgcatacctgggtcctccagagcataagcctgtggcagatacacat
tggtccagccttaaccttaccagttcaaagtttgaagaatttatgactagacatcaagta
catgaaaaagaagagttcaaggctttgaaaacactaagtattttctaccaagctggcact
tccaaagcagggaatcctattttttattatgttgcacgaaggttcaaaactggccaaatc
aatggcgatttgttgatataccacgtcttgctgactttaaagccatactatgcaaagcca
tatgaaatcgtagttgaccttacccatactggacccagcaatcgctttaaaacagacttt
ctgtcaaagtggtttgttgtttttcctggctttgcatatgacaatgtctctgctgtctat
atctataactgtaactcctgggtcagggagtataccaagtatcatgaacggctgctgact
ggcctcaaaggcagcaaaagactcattttcatagactgtcctgggaaacttgctgagcac
atagagcatgaacaacagaaactacctgctgccaccttagccttggaagaggacctgaag
gtattccacaatgccctcaagctagctcacaaagacaccaaagtgtctattaaggttggt
tctaccgcagttcaagtaacctcagcagagagaacaaaagtcctggggcaatcagtcttt
ctaaatgatatctattatgcctcagaaattgaagagatctgcctagtggatgagaaccag
ttcaccttaaccattgcaaaccagggcacgccactcaccttcatgcaccaggagtgtgat
gccatcgtccagtccatcattcacatccgaacccgctgggaactgtcgcagcctgactcc
atcccccagcacaccaagatccgaccaaaagatgtgcctgggacactgctcaatattgca
ttgcttaacttaggcagttcagaccctagtttaaggtcagctgcctataatcttctgtgt
gccttaacctgtacctttaatttaaaaatcgagggccagttactagaaacatcaggttta
tgcatccctgccaacaacaccctctttattgtctccattagtaagacactagcggctaat
gagccacacctcaccttggaatttttggaagagtgtatttctggatttagcaaatctagt
attgaattgaaacacctttgtttggaatatatgaccccatggctgtcaaatctggtccgt
ttttgtaagcataatgatgatgccaaacgacaaagagttacagctattcttgataagctc
ataacaatgaccataaatgagaaacagatgtacccatctattcaagcaaaaatatggggg
agccttgggcagatcacagacctgcttgatgttgtactagacagtttcatcaaaacaagt
gctactggtggcctggggtcaataaaagctgaggtgatggcagatactgctgtagccctg
gcttctggaaatgtgaagctggtctcaagtaaggttattggaagaatgtgtaagataatt
gacaagacatgcttatctccaactccaactttagaacagcatcttatgtgggacgatatt
gcaattttagcccgctatatgctgatgctgtccttcaacaattcccttgatgtggcagct
catctcccctacctcttccatgtggttactttcttagtagccacggggccattgtccctt
agagcttccacacatggattggttattaacatcattcactctctgtgtacctgttcacag
cttcattttagtgaagagaccaagcaagttttgagactcagtcttacagagttctcctta
cctaaattttatttgctgtttggcattagcaaagttaagtcagctgctgtcattgccttc
cgttccagttaccgtgataggtcattctctcctggatcctatgagagagagacttttgct
ttgacttccttagaaacagtcacggaagctttgttggagatcatggaggcatgtatgaga
gatattccaacatgcaagtggctggatcagtggacagaactagctcagagatttgcattc
caatacaatccatccctgcaaccaagagctcttgtggtctttggctgtatcagtaaaaga
gtgtctcatgggcagataaagcagattatccgcattcttagcaaggcacttgagagttgc
ttaaaaggacctgatacttacaacagtcaagttctgatagaagctacagtaatagcatta
accaaattacagccacttcttaacaaggactctcctctgcacaaagccctcttttgggtt
gctgtggctgtgctgcagctggatgaggtaaacttgtattcagcaggcactgcacttttg
gaacaaaacctccacaccttagacagtctccggatattcaacgacaaaagtccagaagaa
gtgttcatggcaactcggaatcctctggagtggcactgcaagcaaatggatcattttgtt
ggactcaacttcaactcaaatttcaactttgcactggttggacacctcttaaaagggtac
agacatccttcgcctgccattgttgcaagaacagtccgaattttacatacactactaact
ctggttaacaaacataggaactgtgacaaatttgaggtgaatacacaaagtgtggcttat
ttagcagctttgcttacggtgtctgaagaagttcgaagtcgctgcagcctcaaacatcga
aagtcccttcttcttactgatatttcaatggaaaatgtccccatggatacatatcccctt
catcatggtgaccccagttataggacactaaaggagaaccagccgtggtcctctccgaaa
ggttctgaggggtaccttgcagccacttatccaacagtgggccagactagtccccgagcc
agaaaatccatgagcttggacatggggcagccttctcaggccaacactaagaagctgctt
ggaacaaggaaaagttttgatcacttgatatcagacacaaaggctcctaaaaggcaagaa
atggaatcagggatcacaacgccccccaaaatgaggagagtagctgaaactgattatgaa
atggcagaaactcaaagaattccctcatcacaacagcacccacacttacgtaaagtttca
gtgtcagaatccaatgttcttttggatgaagaagttcttacggatccgaagatccaggcg
ctgcttcttactgttctagctacactggtaaaatatactacagatgaatttgatcaacga
attctctatgaatacttggcagaggccagtgttgtattccctaaagtttttcctgttgtg
cataatttgttggactctaagatcaacaccctgttgtcattgtgccaagatccaaactta
ctaaatccaatccatggaattgtgcagagtgtggtgtaccatgaggaatcccccccacag
taccagacatcttatctacagagttttggttttaatggcttatggagatttgcaggaccc
ttttcaaagcaaacacaaatcccagactatgctgagcttattgttaagtttcttgatgcc
ttgattgacacatacttgcctggaattgatgaagaaacaagtgaggagtccctcctgacc
cccacctctccttaccctcctgcactgcagagccagcttagtatcgctgccaaccttaac
ctctccaattccatgacctcactcgcaacttcccagcattccccaggaattgacaaggag
aatgtggaactctcccccacctctggccactgtaacagtggacgaactcgccatggatcc
gcaagccaagtacagaagcagagaagtgctggcagcttcaaacgtaatagcattaagaag
atgatgtga
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integrated database retrieval system
