Perognathus longimembris pacificus (Pacific pocket mouse): 125365769
Help
Entry
125365769 CDS
T08928
Symbol
Top2a
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
plop
Perognathus longimembris pacificus (Pacific pocket mouse)
Pathway
plop01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
plop00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
125365769 (Top2a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
plop03032
]
125365769 (Top2a)
03036 Chromosome and associated proteins [BR:
plop03036
]
125365769 (Top2a)
Enzymes [BR:
plop01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
125365769 (Top2a)
DNA replication proteins [BR:
plop03032
]
Eukaryotic type
DNA Topoisomerases
125365769 (Top2a)
Chromosome and associated proteins [BR:
plop03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
125365769 (Top2a)
Centrosome formation proteins
Centriole proteins
125365769 (Top2a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
125365769
NCBI-ProteinID:
XP_048221959
LinkDB
All DBs
Position
17:complement(37792258..37824892)
Genome browser
AA seq
1483 aa
AA seq
DB search
MEVSPLQPLNENMQMTKKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQHM
WVYDEEVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNN
GKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVET
ASREYKKMFKQTWKDNMGKAGEMELKPFSGEDYTCITFQPDLSKFKMQNLDKDIVAIMVR
RAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKLDETGNPLKVIHEQVNHRWEVCL
TMSEKGFQQISFVNSIATSKGGRHVDYVADQIVSKLVDVVKKKNKGGIAVKAHQVKNHMW
IFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAATGCGIVESILNWVKFKAQV
QLNKKCSAVKHNRIKGIPKLDDANDAGSRNSTDCTLILTEGDSAKTLAVSGLGVVGRDRY
GVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTD
QDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKSS
TPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAINLAFSKKQTDDR
KEWLTNFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDG
LKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNL
NLLQPIGQFGTRLHGGKDSASPRYIFTMLSSLARLLFPPKDDHTLKFLYDDNQRVEPEWY
IPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTIEE
LASNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREYH
TDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRD
FFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQRG
YDSDPVKAWKEAQQKVPDDEEDEESDNEKKESVPDSGPSFNYLLDMPLWYLTKEKKDELC
KQRNEKEQELETLKKKSPSDLWKEDLAVFIEELEVVEAKEKQDEQVGLPGKGGKAKGKKI
QMTEVLPSPQGKRVIPQVTLEMKAEAEKKIKRKIKSENTAGTPKEDGIEIESLKERLEKK
QKREPGTKAKKQTTLPFKPVNKGKKKNPWSDSESDMSSTESNFDVPPREMEPRRAATKFK
FTVDPDSDENFSDFDEKNEDEHFAPSDASPPKTKIPPKHTEKELKPQKSTMSGQSSTSVA
GTKKRAAPKKTKTDPALNSDTSEKPGPAKTKTRRKRKPSTSDSNSDSDSNFEKIISKAAT
SKKPRGEASDFLVDVDSVAPRAKSSRARKPIKYLEESDEDDLF
NT seq
4452 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcgccgctgcagcctttaaatgaaaacatgcaaatgaccaaaaagaaaaat
gaagatgctaagaaaagactgtctattgaaaggatctatcaaaagaaaacacaattggaa
catattttgctccgcccagacacctacattggatctgtggaattagtgacccagcatatg
tgggtttacgatgaagaagttggcattaactatagagaagttacttttgttcctggtttg
tacaaaatctttgatgagattcttgttaatgctgccgataataagcagagggaccccaaa
atgtcttgtattagagtcacaattgacccagaaaacaatttaattagtatatggaataat
ggaaaaggaattcctgttgttgaacataaagttgaaaagatgtatgttccagcactcata
tttggacagctcttaacttctagtaactatgatgatgatgaaaagaaagtaacaggtggt
agaaatggctatggagccaaattatgtaacatattcagtaccaaatttactgtggaaaca
gccagtagagaatacaagaaaatgttcaaacagacatggaaggataacatggggaaagct
ggcgagatggagctcaagccttttagtggagaagactacacatgcatcaccttccagcct
gatttatccaagtttaaaatgcaaaacctagacaaagatattgttgcgataatggttaga
agagcatatgatattgccggatcaactaaagatgtcaaagtctttcttaatggaaataag
cttccagtgaaaggattccgtagctatgtggatatgtatctgaaagataagttagatgaa
actggcaacccattgaaagtaatacatgaacaagtaaaccacagatgggaagtatgctta
acaatgagtgaaaagggatttcagcaaattagcttcgtcaatagcattgctacttccaag
ggtggcagacatgttgactatgtagctgatcagattgtgagtaaacttgttgatgtagtg
aagaagaagaacaagggtggtattgcagtaaaagcacatcaggtgaaaaatcacatgtgg
atttttgttaatgccttaattgaaaatccaacttttgactctcagacaaaagaaaacatg
actttacaagccaagagctttggatcaacatgtcaattaagtgagaagttcatcaaagct
gcaactggttgtggtattgtagaaagcatactaaactgggtaaagtttaaggcccaagtc
cagttaaacaagaagtgttcagctgtaaaacataacagaatcaagggaattcccaagctt
gatgatgccaatgatgcagggagccgaaactctaccgattgtacacttattctgactgag
ggagactcggccaaaactttggctgtctcaggccttggtgtagttgggagagacagatat
ggggttttccctctcagaggaaaaatactcaatgtccgagaagcttctcataaacagatc
atggaaaatgcagaaattaacaatatcatcaagattgttggtcttcagtataaaaaaaac
tatgaagatgaagattcattgaagactcttcgttatggaaagataatgattatgacagat
caggaccaagatggttcccatatcaaaggtttgctaattaattttattcatcacaactgg
ccctctcttctgcggcatcgttttctggaggaatttatcactcccattgtgaaggtgtct
aaaaacaagcaagaaatggcattctacagccttcctgaatttgaagaatggaagagttct
actccaaatcataaaaaatggaaagtcaaatattacaaaggtttgggcaccagcacatca
aaagaagctaaggaatactttgcagatatgaaaagacatcgaatccaattcaaatattct
gggcctgaagatgatgctgcaatcaacctggcttttagcaaaaaacagacagatgaccga
aaggaatggctaactaattttatggaggatagaagacaacggaagttacttggccttcct
gaggattatttatatggacaaaccaccacttatctgacatacaatgacttcataaacaag
gaacttatcctattctcaaattctgataatgagagatctatcccatctatggtcgatggt
ttgaaaccgggtcagagaaaagttttgtttacttgtttcaaacgcaatgacaaacgagaa
gtaaaggttgcccagttagctgggtcagtggcagaaatgtcctcttatcatcatggtgag
atgtcattaatgatgaccattatcaatttggctcagaattttgtgggtagcaataatttg
aacctattgcagcccattggtcagttcggtactaggctgcatggtggcaaggattctgct
agtcctcgatacatctttacaatgctcagctctttggctcggttgttattcccaccaaaa
gatgatcacacactgaagttcttatatgatgacaaccaacgtgttgaacctgaatggtac
attcctattataccaatggtgctaataaatggagctgaaggcattggaactgggtggtcc
tgcaaaattcccaacttcgatgttcgtgaagttgtaaataatatcaggcgtttgatggat
ggagaagaacctttgccaatgctgccaagttacaagaacttcaagggtactattgaagag
ctggcttcaaatcaatatgtaattagtggtgaagtagctattcttaattccactaccatt
gaaatctcagagcttcccatcagaacatggacccaaacatacaaagaacaggttctagaa
cccatgttgaatggcactgagaagacaccccctctcatcacagactatagggaataccat
acagatactacagtgaagtttgttgtgaagatgactgaagaaaaactggcagaggcggag
agagttggattacacaaagtctttaaactccaaactagtctcacctgcaattctatggta
ctttttgaccatgtagggtgtttaaagaaatatgacacagtgttggatattctaagagac
ttctttgaactcaggctcaaatattatggattaagaaaagaatggcttctaggaatgctt
ggtgcagaatctgctaaactgaacaatcaggctcgctttatcttagaaaaaatagatgga
aaaattatcattgaaaacaaacctaaaaaagaactaattaaagttctgatccagagagga
tatgattcagatcctgtgaaagcctggaaagaagcacaacaaaaggttccagatgacgaa
gaagatgaggaaagtgataatgaaaagaaagaatctgtaccagattcagggccatccttc
aactaccttcttgatatgcccctttggtatctaaccaaagaaaagaaggatgaactgtgt
aaacaaagaaatgaaaaggagcaagaactggaaaccttaaagaaaaagagtccatcagat
ttatggaaagaagacttagctgtgtttattgaagaactagaggttgttgaagccaaggaa
aaacaagatgaacaagtaggacttcctggaaaagggggaaaagccaaagggaagaaaata
caaatgacagaagttttaccttctccacaaggaaaaagagtcattccccaagtgacctta
gagatgaaagcagaagcagaaaagaaaattaaaaggaaaattaagagtgaaaacactgcg
gggacacctaaggaggatgggatagaaatagaaagcctaaaagaaagattggagaagaaa
cagaaaagagaaccaggtaccaaggcaaagaaacaaactacattgccatttaagcctgtc
aataaaggaaagaagaaaaatccctggtctgattcagaatcagatatgagtagtactgaa
agcaattttgatgtccctccacgagaaatggagccacggagagctgcaacaaagttcaaa
ttcacagtggatccagattcagatgaaaatttttcagattttgacgaaaaaaatgaagat
gaacattttgccccatcggatgctagtccacctaagaccaaaattcccccaaaacatact
gaaaaagaactgaagccacagaaaagtaccatgtcaggtcagtcttccacctctgttgct
ggtaccaaaaaaagggcagctccaaaaaaaaccaaaacagatccagccttaaattctgat
acctctgaaaagcctggccctgccaagaccaagactcgccgcaaaaggaagccatccact
tctgactctaattctgattctgactctaattttgagaaaatcatttctaaagcagccaca
agcaagaaacccagaggggaggccagtgacttccttgtggacgtggactctgtggctcct
cgggcaaagtcttcacgagccaggaaacctatcaagtacctcgaagagtcagatgaagat
gacctgttttaa
DBGET
integrated database retrieval system
