Perognathus longimembris pacificus (Pacific pocket mouse): 125365985
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Entry
125365985 CDS
T08928
Symbol
Lrrk2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
plop
Perognathus longimembris pacificus (Pacific pocket mouse)
Pathway
plop05012
Parkinson disease
plop05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
plop00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
125365985 (Lrrk2)
05022 Pathways of neurodegeneration - multiple diseases
125365985 (Lrrk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plop01001
]
125365985 (Lrrk2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
plop04131
]
125365985 (Lrrk2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
plop04147
]
125365985 (Lrrk2)
Enzymes [BR:
plop01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
125365985 (Lrrk2)
Protein kinases [BR:
plop01001
]
Serine/threonine kinases: TKL group
LRRK family
125365985 (Lrrk2)
Membrane trafficking [BR:
plop04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
125365985 (Lrrk2)
Exosome [BR:
plop04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
125365985 (Lrrk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
Roc
LRR_4
COR-B
Ras
COR-A
LRR_14
LRR_9
WD40_CDC20-Fz
Arf
Beta-prop_WDR36-Utp21_1st
LRR_NXF1-5
WDR55
Ank_2
LRR_13
T2SSE
nSTAND3
AAA_22
Kdo
G-alpha
AAA_16
MMR_HSR1
AAA_7
Beta-prop_EML_2
ABC_tran
GTP_EFTU
AAA_29
NACHT
AAA_23
TniB
MobB
PduV-EutP
FtsK_SpoIIIE
TrwB_AAD_bind
ResIII
TPR_IPO5
NB-ARC
cobW
SRPRB
nSTAND_NTPase5
TsaE
AAA_14
ARM_LIN_2nd
Beta-prop_THOC3
AAA_SelU
Motif
Other DBs
NCBI-GeneID:
125365985
NCBI-ProteinID:
XP_048222302
LinkDB
All DBs
Position
1:complement(61651798..61789792)
Genome browser
AA seq
2525 aa
AA seq
DB search
MASGHGQRCEEEDEETLKKLLVRLNNVQEGKQIETLVQILEDMLVFTYSNHASTLFEGKN
FHVPLLIVLDSYMKVPSVQQVGWSLLCKLIEVCPGTIQSLMGPQDVGNDWEVLGVHQLIL
KMLTVHHANANLSIVGLKALELLLTSGKITLLILDEESDVFLLIVDAMNTFSSNEEVQKL
GCKALCVLFERVSEEQLIEFVENKDYRILLSALQNFKGEEEIVLHVLHCLHSLAIPCNNV
EVLMSGNVRCYKIVIDAMQSFPINEKIQQVSCCLLHRLTLGNFFNMLVLNEVHEFVVKAV
ERYPKNAVLQISALSCLALLTETIFLNQDLEEKNETLEREEEEKEEDKLFWLEACYRALT
WHRKNKHVQEAACWALNNLLMYQNSLHKKIGDEDGQFPAHREVMLAMLMHSSSKEVFQAS
TTALSTLLEQNVDFRKILMSKGIYLNVLELMQKHIHSPEVAESGCRMLSHLFEGSNTPLD
TMAEVVPKIITTMRSHQTLLSVQLEALRAIVHFIVPGMSDDSRDEFQRKLDMVKKQCFKN
DIHKLVLSALNRFIGNPGIQRCGLKIISSLAHFPDVLEMLSLDGAVDSVLHTLQMYPDDQ
EVQCLGLHLLGCLSTKKNLCTGSGLLAKILVSSLQRFKDVIEVQITGFQTIFAILDLSAS
FSKLLLHHSFESVIFYQMSSGITEPKDPQFLNLCCKCFAKLVMDEDLKNVMLQRACDQNN
SIMVECLLLLGADSNQAKEATSLICQVCEKESNPKLVELLLNSGSHEEDVRKALMISMQK
GDSHVISLLLRRLALDLANNSICLGGFGIGKIEPSWLGPLFPDKTSNLRKQTNAGSMLAR
MVLRHQMRRIVEEGAAAGSDGNFSEDVLDKLSEWTFIPDSSMDSVFGQSDDLDSEGSESS
FLVKNKTNSISVGDFYHDPVLQRCSPNLQRHSNSLGPIFDHEDMLKRKMKILSSDDSIRS
SKLQCHMRNSDSISSLASEREYIASLDLSSNELRDIDALSQKCCISGHLEHLEKLELHQN
ALTNFPQQLCETLKCLTHLDLHSNKFTTFPSYLLKMNCLAYLDASRNDIGLPVVLDPGLK
CPTLKQFNLSYNQLSSVPENLTDAVEKLEQLILEGNKISGICFPLSLKELKVLNLSKNHI
SSLPENFLEACPKVESFSARMNFLATMPFLPSSITSLKLSQNKFTCVPDVILNLPHLRSL
DMSSNGIKSLPGPSHWKSLNLRELLFSYNQISILDLSEKAHTWSRVEKLHLSHNKLKEIP
PEIGCLENLASLDVSYNSELRSFPNEMGKLSKIWDLPLDELHLNFDFKHIGCKAKDIIRF
LQQRLKKAVPYNRMKLLIVGNTGSGKTTLLQQLMKTKKSDLGIQGATVGIDVKDWPIQIR
GKRKKDLVLNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKAR
ASSSPVILVGTHLDISDEKQRKACIGKITKELLNKRGFPAIRDYHFVNATEESDALAKLR
KTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKNVPIEFPVIDQKQLLQLVKENQ
LQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVDPKWLCKVMAQILTVKVEGHRKH
PKGIISRRDVETFLSKKKRFPKNYMMQYFKLLEKFQIALPQGEECLLVPSSLSDHRPVIE
LPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRTYWRQGIYLN
WSPEAYCLVGSEILDDCPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDIC
GEGETLLKKWALYSFNDGEDHQKILLDDLMKKAEEGDLLVNPDQPRLTIPISQIAPDLIL
ADLPRNIMLNNDELEFEQAPEFLLGDGSFGSVYRAAYEGEEVAVKIFNKHTSLRLLRQEL
VVLCHLHHPSLISLLAAGIRPRMLVMELAPKGSLDRLLQQDKASLTRTLQHRIALHVADG
LRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFRAP
EVARGNVIYNQQADVYSFGLLLYDILTTGGRIVEGLKFPSEFDELALQGKLPDPVKEYGC
TPWPMVEKLIKKCLKENPQERPTSAQVFDILNSAELICLMKHISISKNIIAECMVATNSN
SNNASIWLGCGHTDKGQLSFLDLNTEEHTTEDVEDSRILCLAFVHLSAEKENWIVSGTQS
GVLLAINAEDRTKRHTLEKMTDSITCLYCNCSKQSKQKNFLLVGTANGNLAVFEDKAVKC
KGAAPLKTLSLGDASTPLMCLSESMNSSEKHIMWGGCGTKVFSFSNDFSIQKLIETRTNQ
LFSYAAFSDLNIIAVAVDTVLYIAKKNSPVVEVWDKKTEKLCELIDCVQFLKEVVVKINK
ESKHRLCYAGRVKALCLQKNTALWIGTGGGHILLLDLSTRRIIRIINNFCDSVRLMVTAQ
LGSLKNIMVVLGYKRKSTEGTQQQKEIQSCLSIWDINLPHEVQNLEKHIEVRKELAEKMR
KTSIE
NT seq
7578 nt
NT seq
+upstream
nt +downstream
nt
atggccagtggtcacggtcaaaggtgcgaagaggaggacgaggaaactctgaagaagttg
ctagtcagactgaacaacgtccaggaaggaaaacagatagagacgctggttcaaatcctg
gaagacatgctggtgttcacctactccaatcacgcttccacgttatttgaaggcaaaaat
ttccacgtgcctctgttgatcgttttggattcctatatgaaagtccccagtgtgcagcag
gtgggctggtcccttctgtgtaaattaatagaagtctgtccaggtacaattcagagctta
atgggaccccaggatgttggaaatgattgggaagtccttggtgttcaccaactgattctt
aaaatgttaactgttcatcatgctaatgcaaacctttcaatagttggactgaaggcctta
gaactcctgctaacttcaggcaagatcacattgttgattctggatgaagaaagtgatgtt
ttcttattaatcgttgatgccatgaacacattttcatccaatgaagaggtccagaaactt
ggatgcaaggcattatgtgtgctgtttgaaagagtgtctgaggaacaactaattgaattt
gttgagaacaaagattataggatattgttaagtgcattacaaaactttaaaggtgaagaa
gaaattgtgctccatgtactgcactgtttgcattccctagcgattccttgcaataatgtt
gaagtcctcatgagtggcaatgtcaggtgttacaaaattgtgatagatgccatgcaatca
ttccccatcaatgaaaagattcagcaagtcagttgctgcttgctccatcggctgacctta
ggtaattttttcaatatgctagtattaaatgaggttcatgaatttgtggtgaaggctgtg
gagagatatccaaagaacgcagtgttacaaatctcagccctcagctgcttagcacttctg
actgagaccattttcttaaatcaagacttagaagaaaagaatgagactctggagagagag
gaggaggagaaggaagaagataaactgttctggctggaagcctgttacagagctttaaca
tggcacagaaagaataaacatgtacaggaggctgcatgttgggcgttaaacaatctcctc
atgtaccaaaacagtttacacaagaagattggagatgaagatggccagtttccagctcac
agggaggtgatgctggctatgctgatgcattcttcctccaaggaagtcttccaggcgtcc
accactgcgttgtcaactctcttggaacaaaatgttgattttagaaaaatcctgatgtca
aaaggaatatacctgaatgttttggagttaatgcagaagcacatacattctccggaagtg
gctgaaagtggatgtaggatgctcagtcatctttttgaaggaagtaacactcccctggat
acaatggcagaagtggtccctaagataataacaactatgcgaagccaccagacattgttg
tctgtgcagctggaggctctccgggccattgtgcattttatagtgcctggcatgtcagat
gattccagagatgaatttcagcgtaaactagatatggttaaaaaacaatgtttcaagaat
gatattcacaagcttgtactatcggctttgaacaggtttattggcaatcctgggattcag
aggtgcggattgaaaataatttcttcactagcacattttcctgatgtgctggagatgctg
tccttggatggtgctgtggactctgtacttcatacactgcagatgtatccagatgaccaa
gaagttcagtgtctaggtttacatctcttaggatgcttgagtaccaagaagaatttatgc
acaggaagtgggctgctggctaagattctagtttccagtttacaacggtttaaagatgtt
attgaagtgcagatcacaggatttcagacaatctttgccattctggacctgtcagcatct
ttttctaagctgctcctgcatcattcatttgagtccgtaatattctatcagatgtcgtct
ggtatcacagaaccaaaggacccacagtttctcaatctctgttgcaaatgttttgcaaaa
ctggtgatggatgaagatttaaaaaatgtgatgttacaaagagcctgtgatcagaataat
agcatcatggtagaatgtttgcttctcctgggagcagattccaatcaagccaaggaggca
acttctttaatttgtcaggtctgtgagaaagagagcaaccccaaattggtggagctgctg
ctgaatagcggatcccatgaagaggatgtaaggaaagcgttgatgattagcatgcagaag
ggggacagccatgtaatcagcttgctcttaaggaggctggcactagatctggccaacaac
agcatctgcctgggaggatttggtataggaaaaattgaaccttcttggctgggtccttta
tttccagataagacatccaatttaaggaaacaaacgaatgcaggttctatgctagcaaga
atggtactcaggcaccagatgagaaggatcgtggaggaaggagcagctgcaggcagtgat
gggaatttctctgaagatgtactggataagctcagtgaatggactttcattccagattct
tccatggacagtgtgtttggtcagagtgatgatctggatagtgaaggaagtgaaagttca
tttcttgtgaaaaacaaaacaaattccattagtgtgggagatttttaccatgatcctgtg
ttgcaacgttgctcaccaaatttgcaaaggcattcgaattcattgggacccatttttgat
catgaagatatgctgaagcgaaaaatgaaaatattgtcttcagatgattcaatcaggtca
tcaaaacttcagtgtcatatgaggaattcagacagcatttcctccttggcttctgagaga
gagtacattgcatcattagacctttcatccaatgagctcagagatattgatgccctgagc
cagaaatgctgtataagtggtcatttggagcatctcgaaaagttggagcttcaccagaat
gcactcaccaactttccacagcaattatgtgaaaccctgaagtgcttgacgcacttggat
ttgcacagtaataaattcacaacctttccctcctacttgctgaaaatgaattgccttgcc
tacctggatgcctctcgcaatgacattggacttccagtggtgttagatcctggcctgaag
tgccccaccttgaagcagttcaacctgtcctacaaccagctctcttctgtacctgagaac
ctcactgatgctgtggagaaactggagcagctcattttagaagggaataaaatatcagga
atatgtttccctttgagcctgaaggaattgaaggttttaaaccttagtaagaaccacatc
tcatccctgccagagaactttcttgaagcttgtccaaaagtagagagtttcagtgccaga
atgaattttcttgctactatgcctttcttgccttcttccataacaagcctaaaattatct
caaaacaaatttacatgtgttccagatgtaattttaaatctaccacacttacggtcattg
gacatgagcagcaatggcattaaaagtctgcctggaccttcacactggaaatctttgaac
ttaagggagctcttgtttagctacaatcagatcagcatcttggacttgagtgaaaaagca
cacacctggtctagagtagagaaactacacctttcccataataaactgaaggagattcct
cctgagattggctgtcttgaaaatctggcatctctggacgtcagttacaactcggagctg
agatccttccccaacgagatgggaaagttaagcaaaatatgggatcttcctctggatgaa
ttgcatctaaatttcgattttaaacatattggatgcaaagcaaaggacatcatcagattt
cttcagcaacggttaaagaaggctgttccctacaaccgcatgaaactcctgattgtggga
aatactgggagtggtaaaaccaccttactgcagcagttaatgaaaaccaagaaatcggat
cttgggattcagggtgctacagtgggcattgatgtgaaagactggcccatccaaatcagg
ggcaagaggaaaaaagaccttgttctaaatgtgtgggattttgcaggtcgtgaagaattc
tacagcactcacccccatttcatgacccagcgagcactgtaccttgctgtctacgacctc
agcaaggggcaggcagaagtggatgccatgaaaccctggctcttcaatataaaggctcgt
gcttcttcctctcctgtcattcttgtgggcacacatctggacatttctgatgagaagcag
cgcaaggcctgtataggaaaaatcaccaaggagctgctgaacaagcgaggctttcctgca
atacgagattaccactttgtgaatgccaccgaggaatctgatgctctagctaaacttagg
aaaactatcataaatgagagtctgaatttcaagattcgagatcagcctgttgtgggacag
ctaattccagactgctatgtagaacttgagaaaatcattttatcagagcgtaaaaatgtg
ccaattgaatttcctgtaattgaccagaagcaattattacaactagtgaaagaaaaccag
ctacaattagatgaaaatgagctccctcatgcagttcatttcttaaatgaatcaggagtc
cttcttcattttcaagacccagcactacagttaagtgacttatattttgtggatccaaag
tggctttgtaaagtcatggctcagattttgacagtaaaagtggaaggccatcggaaacat
cctaaaggaattatttcacgtagagatgtggaaacatttctttctaagaagaaaagattt
ccgaagaactacatgatgcagtactttaaactcttagaaaagttccagattgccttgcca
caaggagaagagtgtttactggttccaagcagtttatcggaccacagacctgtgatagag
cttcctcattgtgagaactctgaaattatcattcgactctatgaaatgccctattttccc
atgggattttggtcaagattaatcaatcgattacttgaaatttcaccttacatgctttct
ggaagagaacgagcacttcgcccaaacagaacatattggcgacaaggaatctacttgaat
tggtctcctgaggcttattgtctggtgggatctgaaatcttagatgattgtccagagagt
ttcttaaaaatcacagttccttcttgtagaaaaggctgcattcttttgggccaagttgtg
gaccacattgattctcttatggaagaatggtttcctgggttgctggagattgatatctgt
ggtgaaggtgaaactctgttgaagaaatgggcattatacagttttaatgatggcgaagat
catcaaaaaatcttacttgatgacttgatgaagaaagcagaagaaggagaccttctagta
aacccagatcaaccgaggctcaccattccaatatctcagattgcccctgacttgattttg
gctgacctgcctagaaatattatgttgaataatgatgagttggagtttgagcaagctcca
gagtttctcttaggtgatggcagttttggatctgtttatcgagcagcctatgaaggtgag
gaagtggctgtgaagatttttaataaacatacatcacttagattgttacgacaagagctg
gtggtgctttgccacctccatcaccccagcttaatatctttgctggcagctggaattcgc
cctcgaatgttggtgatggagctggcccccaagggctccttagatcgcctgcttcagcag
gacaaagccagcctcacccgcactctccagcacaggatcgcccttcatgtggctgatggc
ttgaggtacctgcactcagccatgattatataccgagacttgaagccccataacgtgctg
ctttttaccctgtaccccaatgcagccatcattgcgaagattgctgactatgggattgct
caatactgctgcagaatgggaataaaaacatcagagggcacaccaggatttcgagcacct
gaagttgccagaggaaatgtcatttacaatcagcaggctgatgtgtactcgtttggcctg
ttactctatgacattttgacaactggaggtagaatagtagaaggtttgaagtttccaagt
gagtttgatgaattagcactacaaggaaaattacctgatccggttaaagaatatggctgt
accccatggcctatggtagagaagctaattaaaaaatgtttgaaagaaaaccctcaggaa
aggcctacttctgcccaggtctttgacattctgaattcagctgagctaatctgtctgatg
aaacacatttcaatatcaaaaaacattatagctgaatgcatggttgctacaaattctaac
agcaataatgcaagcatttggctgggctgtgggcacacagacaaaggccagctctctttt
cttgacttaaacactgaagaacacactactgaggacgttgaagatagtagaatattgtgc
ttggcctttgtgcatctctctgctgagaaggagaactggatcgtgtctgggacacagtct
ggtgttctcctggccatcaatgctgaagacaggaccaagaggcataccctggaaaagatg
actgattccattacttgcttgtattgtaactgctccaagcagagcaagcagaaaaatttt
cttttggtgggaactgctaatggtaacttagcagtttttgaagataaagctgttaagtgt
aaaggagcggctcccttgaagaccctgagcctgggagatgcaagcactccacttatgtgc
ttgagtgaatccatgaattcctctgagaaacacatcatgtggggaggatgtggcacaaag
gttttctcattctctaatgacttctccattcagaagctcattgagacaaggacaaaccag
ctgttttcctatgcagctttcagtgatttgaacatcatagcagttgctgtggacacagtg
ctctatatcgcaaagaaaaacagccctgtcgtggaagtgtgggacaagaaaacagaaaaa
ctctgtgaactaatagactgcgtgcagtttttaaaggaagtcgtggtaaaaataaacaag
gaatcaaagcacaggctgtgctatgccgggagagtaaaggcactctgccttcagaagaac
acggctctctggataggaactggagggggccatattttactcctggatctttccactcgg
cgaatcatacggataattaacaacttctgcgattctgttagactcatggtgacagcacaa
ttaggaagtcttaaaaatatcatggtggttttggggtacaaacggaaaagtacagaaggt
acacaacaacaaaaagaaatacaatcttgcttgtctatttgggatatcaatcttccacat
gaagtgcaaaatttggaaaaacacattgaagtgaggaaagaattagctgaaaaaatgaga
aaaacatccattgaatag
DBGET
integrated database retrieval system
