Photorhabdus laumondii subsp. laumondii TTO1: plu3673
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Entry
plu3673 CDS
T00149
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase (alpha-isopropylmalate synthase) (alpha-IPM synthetase)
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
plu
Photorhabdus laumondii subsp. laumondii TTO1
Pathway
plu00290
Valine, leucine and isoleucine biosynthesis
plu00620
Pyruvate metabolism
plu01100
Metabolic pathways
plu01110
Biosynthesis of secondary metabolites
plu01210
2-Oxocarboxylic acid metabolism
plu01230
Biosynthesis of amino acids
Module
plu_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
plu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
plu3673 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
plu3673 (leuA)
Enzymes [BR:
plu01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
plu3673 (leuA)
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Motif
Other DBs
NCBI-ProteinID:
CAE16046
Pasteur:
plu3673
UniProt:
Q7N129
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Position
4325616..4327178
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AA seq
520 aa
AA seq
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MNQQVIIFDTTLRDGEQALQASLCVNEKLQIALALERMGVDIMEVGFPVSSPGDFESVQT
IAKQIKNSRVCALARCVEKDIDVAAEALKVADAFRIHVFLATSDLHIESKLKKTFENVME
MATQSIKRARRYTDDVEFSCEDAGRTPIDNLCRIVENAIKAGATTINIPDTVGYTTPYQF
GGIITNLIERVPNIDKAIISVHCHDDLGMSVANSITAVQSGARQIEGTINGLGERAGNCS
LEEVIMAIKVRQQMLGVYTNINHQEIYRTSQLVSQLCNMPIPANKAIVGSNAFSHSSGIH
QDGVLKNRETYEIMTPESIGLKEIQLNLTSRSGRAAVKHRMEEMGYQDKDYDLGSLYEAF
LRLADKKGQVFDYDLEALAFINLQQQEPEFFHLDNFNIQSGSNVMATAAVCLVCGKELKS
EAATGNGPVDAVYQAISRITEYPIELVSYQLSGKGQGKNALGQVNIVVECFGRRFHGMGL
ETDIVESSAKAMVHALNCVWRTEQVKKEKQRIQQNTKEMV
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atgaaccagcaagttattatcttcgacaccacgttacgtgatggagaacaagcattacag
gccagcttatgtgtgaacgaaaaactccagattgccttggccttggagagaatgggtgtt
gatatcatggaagtcggttttccagtttcctctcctggtgattttgaatctgtacagacg
atcgctaagcagataaaaaacagccgtgtttgcgccttagcccgttgtgtagaaaaagac
attgacgtggcagcagaagcattaaaagttgcagacgcttttcgaatccacgttttttta
gccacttccgatttacatattgaatccaagctgaaaaaaacattcgaaaatgtcatggaa
atggcaacgcaatcaatcaaacgagcacgtcgttacactgatgatgtcgaattctcctgt
gaagatgcgggccgtacacctattgataatctgtgtcggatcgttgaaaacgctatcaaa
gcaggcgcaacaacgatcaatatcccagatactgtcggttacaccacgccatatcaattt
ggcggcatcatcactaacttgatcgaacgcgttcctaatattgataaagcgataatatcc
gtccattgccacgatgatttggggatgtctgtcgccaactctatcacagcagtacaatcc
ggtgcccgtcagatagaagggacgataaacggtctgggtgaacgtgccggtaactgttca
ctggaagaagtcattatggcgattaaggtccgtcagcaaatgttaggcgtttatactaat
atcaaccatcaggaaatttaccgcaccagtcagttggtcagtcaattatgcaatatgccg
atccccgcgaataaagcaattgttggtagcaatgcattttcccactcatccgggattcat
caagacggggtactgaaaaatcgtgaaacttacgaaattatgacaccagagtccatcggc
ctgaaagaaattcaattgaacctgacttcccgttctggtcgcgccgcagtgaaacaccgt
atggaagagatgggatatcaggataaagattacgatctgggtagcttatacgaagccttt
ttacgcctggcagataaaaaaggccaggtatttgactatgatttggaagccttagcgttc
atcaatttgcaacaacaagaacccgaatttttccatctggacaactttaatatccaatct
ggctccaacgtgatggcaacagccgctgtatgtttagtgtgtggtaaagagttgaaatca
gaagcggccacaggtaacggcccggtagatgctgtctatcaggcaatcagtcgaataact
gaatacccaattgaactggtttcttatcagttatcaggtaaaggccaaggaaaaaatgca
ttgggtcaggtcaatatcgttgtcgaatgctttggacgtcgcttccacggcatgggatta
gaaaccgatattgttgaatcctctgccaaagcaatggttcatgctctgaactgcgtttgg
cgtacagagcaagttaagaaagagaaacaacgcatacagcaaaatacaaaggaaatggtg
taa
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