Providencia manganoxydans: JI723_03545
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Entry
JI723_03545 CDS
T08377
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
pmag
Providencia manganoxydans
Pathway
pmag00260
Glycine, serine and threonine metabolism
pmag00261
Monobactam biosynthesis
pmag00270
Cysteine and methionine metabolism
pmag00300
Lysine biosynthesis
pmag01100
Metabolic pathways
pmag01110
Biosynthesis of secondary metabolites
pmag01120
Microbial metabolism in diverse environments
pmag01230
Biosynthesis of amino acids
Module
pmag_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
pmag_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
pmag_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
pmag_M00526
Lysine biosynthesis, DAP dehydrogenase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
pmag00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
JI723_03545 (thrA)
00270 Cysteine and methionine metabolism
JI723_03545 (thrA)
00300 Lysine biosynthesis
JI723_03545 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
JI723_03545 (thrA)
Enzymes [BR:
pmag01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
JI723_03545 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
JI723_03545 (thrA)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
DUF2652
Motif
Other DBs
NCBI-ProteinID:
QQO63075
LinkDB
All DBs
Position
820943..823402
Genome browser
AA seq
819 aa
AA seq
DB search
MRVLKFGGTSVANDERVLNVVDIAESKLADGQVALVLSAPAKITNHLVAMIDKTVAGQDV
ITHVNDAEMIFANLLKGLKEKQPGFEYDKLKKLTEQEFAQIKQVLHGITLLGQCPDSINA
SIICRGEKLSIAIMESVLKARGHNVTVINPVENLLAVGHYLESTVDINESTKRIADLNIP
KDHFVLMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRLV
PDARLLKGMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTTNPSAPGTLIGDGQT
DDSTPVKGITNLNNMAMINVSGPGMKGMVGMAARIFSVMSRKGISVVLITQSSSEYSISF
CVPQNELGRARHALEEEFYLELKDGVLDPLDVMEQLAIISVVGDGMRTLKGISARFFSAL
TRGNINIVAIAQGSSERSISAVIANGSATTAVRLCHQMLFNAEQVIEAFIIGVGGVGNAL
IEQIRRQQQWLKQKHIDLRVCGIANSRAMLTNMQGISLDNWKQELDQATEPFSLSRLIRL
EREYHFLNPVIIDCTSNQEIAEQYVNFLKDGFNVVTPNKKANTLSMDYYHQLRLAGEASK
RKFLYDTNVGAGLPVIENLQNLLNAGDELVHFSGILSGSLSFIFGKLDEGMSLSEATTLA
KEKGFTEPDPRDDLSGMDVARKLLILAREAGYQLELSDIEIEAVLPVEFDSSGDVATFMS
RLPQLDQQFADRIKAAEAEEKVLRYVGLIEEGRCQVKIVAVDGNDPLFKVKNGENALAFY
TRYYQPIPLVLRGYGAGNDVTAAGVFADMLRTLSWKLGV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgtgcttaaatttggcggtacttcggttgcaaatgacgaacgagtactcaatgtt
gttgacatcgctgaaagtaaattggctgatggacaagtggctttggtgttatcagcacca
gcaaaaatcacgaaccatttagtcgcaatgattgataaaacggtagcaggtcaggatgtc
atcacgcatgtgaatgatgcagaaatgatttttgctaacctcctaaaaggattgaaagaa
aaacagccgggttttgaatacgacaagttgaaaaaactgactgaacaagaatttgcacaa
ataaaacaagtactgcatggtattactcttctaggccaatgccctgatagcatcaatgct
tcaatcatttgccgaggtgaaaaactctctattgcaatcatggaatcagtgctaaaagca
cgcgggcacaacgttaccgtgattaatccagttgaaaatttactcgctgttggtcactac
ctcgaatcaacggtcgatattaacgaatcaaccaagcgtatcgctgacttaaatatcccg
aaagatcactttgtattaatggcgggtttcaccgcaggaaatgataaaggtgaactagtg
gtattaggccgtaatggttccgattactcagcagccgtgcttgccgcttgcttacgcgct
gattgttgtgagatctggactgacgttgatggggtttatacttgcgatccccgtttggta
cctgatgcacgcttattgaagggaatgtcttatcaagaagcgatggaactctcctatttt
ggcgcaaaagtcttgcatccacgcactatcgccccaattgctcaattccaaattccttgc
ttaattaaaaataccaccaacccaagtgcaccgggaactctgattggtgatggtcaaact
gatgacagtacaccagttaaagggatcaccaatcttaataatatggcgatgatcaacgtc
tctggccccggtatgaaaggaatggttggcatggcggcacgtattttctcggtgatgtca
cgcaaagggatttctgtcgtactgatcactcaatcatcttctgaatacagtatcagcttc
tgtgtgcctcaaaatgagttaggccgtgcacgtcacgcattagaagaagaattctattta
gagttgaaggatggtgtattagaccctctggatgtgatggaacaactagcgatcatttca
gtcgttggtgatggtatgcgtacacttaaagggatttcagcacgtttcttctctgcatta
acccgtggcaatatcaatatcgttgcgattgctcagggctcttctgagcgctcaatttca
gccgttatcgctaatggttcagcaaccacggcagtgcgtctatgtcatcaaatgttgttt
aatgcagagcaagtcatcgaagcctttatcattggtgttggtggtgtcggtaatgcgctg
atcgaacaaattcgccgtcagcaacaatggttgaagcaaaaacatatcgacctgcgtgtt
tgtggtattgcgaactcaagggctatgctgaccaatatgcaaggcatttcactggataat
tggaaacaagaactcgatcaagcaaccgaaccatttagcctaagtcgcttgatccgttta
gagcgtgagtaccatttcctcaatccagtgattattgattgcacatcgaatcaagagatt
gctgagcaatatgtgaatttcttaaaggatggctttaacgtcgttaccccaaacaaaaaa
gccaacacattatcaatggattactaccatcaactgcggttagcaggggaagcttcaaag
cgtaaattcctttacgatactaacgttggcgcaggtttgcctgttatcgaaaaccttcag
aatttacttaatgcaggtgatgaactggttcactttagcggtattctttcgggctcactc
tctttcatttttgggaagctggatgagggaatgtcattgtctgaagcgacaacattagca
aaagaaaaaggattcactgaacctgacccacgtgatgatttatcgggtatggacgttgct
cgtaaactcttgatccttgcacgcgaagcgggctaccaactagagctaagtgatattgaa
atcgaagcggtactccctgttgaatttgatagctctggtgatgttgcaaccttcatgtca
cgtttaccgcaacttgaccaacaatttgctgatcgtataaaagccgcagaagcagaagaa
aaagtgttacgctatgttggattaattgaagaagggcgctgccaagtgaaaattgttgcc
gttgatggtaatgatccactcttcaaagtaaaaaatggcgaaaacgcattggctttctat
acacgctattaccaaccaattcctttagttctcagagggtatggtgccggtaatgatgtt
actgctgccggcgtatttgcagacatgttacgtaccctatcatggaaattgggagtctga
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