Peromyscus maniculatus bairdii (prairie deer mouse): 102909508
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Entry
102909508 CDS
T11302
Symbol
Fpgs
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
pmav Peromyscus maniculatus bairdii (prairie deer mouse)
Pathway
pmav00790
Folate biosynthesis
pmav01100
Metabolic pathways
pmav01240
Biosynthesis of cofactors
pmav01523
Antifolate resistance
pmav04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
pmav00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
102909508 (Fpgs)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
102909508 (Fpgs)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102909508 (Fpgs)
Enzymes [BR:
pmav01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
102909508 (Fpgs)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
102909508
NCBI-ProteinID:
XP_006983555
Ensembl:
ENSPEMG00000015710
UniProt:
A0A6I9LWM6
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Position
4:7477301..7497289
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AA seq
590 aa
AA seq
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MSWARSHLCSALSLAAVSARGATAEGAARRWLSAWPAPQEPGMEYQDAVRMLNTLQTNAS
YLEQVKRQRSDPQAQLEAMEVYLVRSGLQVEDLNRLNIIHVTGTKGKGSTCAFTERILRN
YGLKTGFFSSPHLVQVRERIRINGKPISPELFTKHFWRLYHQLEEFKDDSHISMPAYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA
WQKGGIFKPGVPAFTVLQPEGPLAVLRDRAQQTSCPLYLCPPLEALEEGGLPLTLGLEGE
HQRSNAALALQLAHSWLEQRDHQDIRELKVSRPGTRGQLPLAPVFHPTSHMRHGLRDTEW
PGRTQVLRRGPLTWYLDGAHTTSSMQACARWYCQSLQRSKRPSGGPEVHVLLFNSTGDRD
SAALLKLLQPCRFDYAVFCPNLTEVSSTENADQQNFTVTLDQVLLRCLQHQQHWSCLAEK
QAGPDLWSGPGGGAEPGGPGGSLLLALHPPHSASTDSLVFSCISHALQWISQGRDPIFQP
PNPPRSLLSHPTASSGASILREAAAVHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1773 nt
NT seq
+upstream
nt +downstream
nt
atgtcgtgggcgcggagccacctgtgctcggctctgtccctggcagctgtttctgcgcgt
ggtgcaacggccgagggcgcggcgcggcggtggttgagcgcgtggcccgcgccgcaggag
cccggcatggagtaccaggatgctgtacgcatgctcaacaccctgcagaccaatgccagc
tacctggagcaggtgaagcgtcagcggagtgaccctcaggcgcagctggaagccatggag
gtgtacctggtacggagtggactgcaggtggaggacctaaaccgtctaaacattatccac
gtcactgggaccaaaggaaagggctccacctgtgccttcactgaacgcatcctgcggaac
tacggcctgaagacaggcttctttagctctccccacctggtgcaggtgcgtgaacggatt
cgcatcaatgggaagcccatcagtcccgaacttttcaccaagcacttctggcgcctctat
caccagctggaggagttcaaggatgacagccacatttccatgcctgcttacttccgcttc
ctcacgctcatggccttccacgtcttcctccaagagaaggtggacctggctgtggtagaa
gtgggcattggcggggcttatgactgcaccaacatcatcagaaagccagtggtgtgtgga
gtgtcctctcttggtattgaccacaccagcctgctaggagacacggtggagaagatagcc
tggcagaaagggggcatctttaagcctggtgtccctgcctttactgtgctacagccagaa
ggtcccctggccgtgctgagggatcgagcccagcagacctcatgtcctctgtacctgtgt
ccaccgttggaagccctggaagagggtgggctgccgctgaccctgggcctggagggagag
caccagcggtccaatgcagccttagccttgcagctggcccatagttggctggagcagcgg
gaccaccaggacatccgggagctgaaggtgtccaggccaggcacacgggggcagctgcct
ctggcacctgtcttccatcccacctctcacatgagacatgggcttcgggacacggagtgg
cctggtcggacacaggtgctgcggcggggacctctcacctggtacctggacggcgcacac
accaccagcagtatgcaggcctgtgcgcgctggtattgccagtcattacagcgcagtaaa
cgccccagtggtgggcctgaagtacacgtcctgctgttcaactccaccggtgacagggac
tctgccgctctgctgaagctgctgcagccctgccggtttgactacgccgtcttctgcccc
aacctgacagaggtgtcatccacagaaaacgcagaccagcagaacttcacggtgactctg
gaccaggtgctgctccgctgcctccaacaccagcaacactggagctgcctggccgagaaa
caagccggccccgacctctggagcggccccggcggcggcgcagagcccggcgggccgggg
ggctccctgctgctggcgctgcacccacctcactctgctagcacggactccctagttttt
agctgcatctcccacgccctgcagtggatcagccaaggccgggatcccatctttcaaccc
ccgaaccccccgaggagcctcctcagccaccccacagccagcagtggggcaagcattctc
cgtgaggctgctgcggtccacgtactggtcacggggagcctgcacctggtgggtggagtc
ctaaagctgctggagccttccctgtcccagtag
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