KEGG   Peromyscus maniculatus bairdii (prairie deer mouse): 102910356
Entry
102910356         CDS       T11302                                 
Symbol
Rps6kb2
Name
(RefSeq) ribosomal protein S6 kinase beta-2
  KO
K04688  ribosomal protein S6 kinase beta [EC:2.7.11.1]
Organism
pmav  Peromyscus maniculatus bairdii (prairie deer mouse)
Pathway
pmav01521  EGFR tyrosine kinase inhibitor resistance
pmav01522  Endocrine resistance
pmav04012  ErbB signaling pathway
pmav04066  HIF-1 signaling pathway
pmav04140  Autophagy - animal
pmav04150  mTOR signaling pathway
pmav04151  PI3K-Akt signaling pathway
pmav04152  AMPK signaling pathway
pmav04211  Longevity regulating pathway
pmav04213  Longevity regulating pathway - multiple species
pmav04350  TGF-beta signaling pathway
pmav04371  Apelin signaling pathway
pmav04666  Fc gamma R-mediated phagosome formation
pmav04714  Thermogenesis
pmav04910  Insulin signaling pathway
pmav04931  Insulin resistance
pmav05163  Human cytomegalovirus infection
pmav05165  Human papillomavirus infection
pmav05170  Human immunodeficiency virus 1 infection
pmav05200  Pathways in cancer
pmav05205  Proteoglycans in cancer
pmav05207  Chemical carcinogenesis - receptor activation
pmav05210  Colorectal cancer
pmav05212  Pancreatic cancer
pmav05221  Acute myeloid leukemia
pmav05224  Breast cancer
pmav05225  Hepatocellular carcinoma
pmav05226  Gastric cancer
pmav05231  Choline metabolism in cancer
pmav05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:pmav00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    102910356 (Rps6kb2)
   04350 TGF-beta signaling pathway
    102910356 (Rps6kb2)
   04371 Apelin signaling pathway
    102910356 (Rps6kb2)
   04066 HIF-1 signaling pathway
    102910356 (Rps6kb2)
   04151 PI3K-Akt signaling pathway
    102910356 (Rps6kb2)
   04152 AMPK signaling pathway
    102910356 (Rps6kb2)
   04150 mTOR signaling pathway
    102910356 (Rps6kb2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    102910356 (Rps6kb2)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagosome formation
    102910356 (Rps6kb2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    102910356 (Rps6kb2)
  09149 Aging
   04211 Longevity regulating pathway
    102910356 (Rps6kb2)
   04213 Longevity regulating pathway - multiple species
    102910356 (Rps6kb2)
  09159 Environmental adaptation
   04714 Thermogenesis
    102910356 (Rps6kb2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102910356 (Rps6kb2)
   05205 Proteoglycans in cancer
    102910356 (Rps6kb2)
   05207 Chemical carcinogenesis - receptor activation
    102910356 (Rps6kb2)
   05231 Choline metabolism in cancer
    102910356 (Rps6kb2)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    102910356 (Rps6kb2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102910356 (Rps6kb2)
   05212 Pancreatic cancer
    102910356 (Rps6kb2)
   05225 Hepatocellular carcinoma
    102910356 (Rps6kb2)
   05226 Gastric cancer
    102910356 (Rps6kb2)
   05221 Acute myeloid leukemia
    102910356 (Rps6kb2)
   05224 Breast cancer
    102910356 (Rps6kb2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102910356 (Rps6kb2)
   05163 Human cytomegalovirus infection
    102910356 (Rps6kb2)
   05165 Human papillomavirus infection
    102910356 (Rps6kb2)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    102910356 (Rps6kb2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102910356 (Rps6kb2)
   01522 Endocrine resistance
    102910356 (Rps6kb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pmav01001]
    102910356 (Rps6kb2)
Enzymes [BR:pmav01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     102910356 (Rps6kb2)
Protein kinases [BR:pmav01001]
 Serine/threonine kinases: AGC group
  RSK family [OT]
   102910356 (Rps6kb2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 Seadorna_VP7
Other DBs
NCBI-GeneID: 102910356
NCBI-ProteinID: XP_006980603
Ensembl: ENSPEMG00000016166
UniProt: A0A6I9LL37
LinkDB
Position
1:complement(156898372..156905002)
AA seq 485 aa
MAAVFDIDLETEEGSEGEGEPEFSPAEVCPLGELRAAGLETVGHYEEVELTESSVNLSPE
RIGPHCFELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAER
NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITL
ALGHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEGAITHTFCGTIEYMAPEI
LVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIMKGKLVLPPYLTPDARDLA
KKFLKRNPVQRIGGGPGDAAEVQRHPFFRHINWDDLLARRVDPPFRPSLQSEEDVSQFDT
RFTRQTPVDSPDDTTLSESADQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRT
PISPLKFSPFEGFRPSPGPPEPMEPSLPPLLPPPSPPPPTSTAPLPIRPPSGTKKSKKGR
GRPGR
NT seq 1458 nt   +upstreamnt  +downstreamnt
atggccgccgtgtttgatatagacttggagaccgaagaaggcagcgagggcgagggcgaa
ccagagttcagccctgcggaggtgtgtccccttggcgagttgagggctgctggcctggag
acggtgggacactatgaggaggtggagctgacagagagcagcgtgaacctgagccctgaa
cgcatcggcccccactgctttgagcttctgagtgtgctgggcaaggggggctatggcaag
gtgttccaggtgagaaaagtgcaaggcaccaacttgggcaaaatatatgccatgaaagtc
ttgaggaaggccaagattgtacgcaatgccaaggacacagcacatacccgggctgagcgg
aacattctagaatccgtgaagcatcccttcattgtggaactggcctacgctttccagaca
ggtggcaaactctacctcatcctggagtgcctcagtggtggtgagctcttcacacatctt
gagcgagaaggcatcttcttggaagacacagcctgcttctacctggctgagatcacactg
gccctgggccatctccattcccaaggcatcatctaccgggatctcaagcctgagaacatc
atgcttaacagccagggccacatcaaactgacagactttggactctgcaaagagtccatt
catgagggtgctatcactcacaccttctgtggcaccattgagtacatggccccagagatt
ctagtgcgcagtggccacaaccgggcagtggactggtggagcctgggggccctgatgtac
gacatgctcactggatcgccgcccttcaccgcggagaaccgaaagaaaaccatggataaa
atcatgaaagggaagctggtgctgcccccctacctcaccccggatgctcgggatcttgcc
aaaaagtttctgaagcggaatcccgttcagcgaattgggggtggcccaggagatgctgct
gaggtgcagaggcaccccttcttccggcacatcaattgggatgacctcctggcccgccgt
gtggaccctcccttcaggccgagtctgcagtcagaagaggatgtgagtcagtttgacaca
cgcttcacacggcagacgccggtagacagccccgacgacacaaccctcagcgagagtgct
gaccaggccttcctgggcttcacatacgtggcaccttctgtcctggacagcatcaaggag
ggcttctcgttccagcccaagctgcggtcccccaggcgtcttaacagcagcccccgcacc
cccatcagccccctcaagttctctccctttgaggggttccggcccagccctggcccgcca
gagcccatggagccgtctctacctccgcttctgccaccaccgtcgccgccgccacccaca
agcacggcccctcttcccatccgtcccccctcagggaccaagaaatccaagaagggccgc
gggcgcccagggcgctaa

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