Peromyscus maniculatus bairdii (prairie deer mouse): 102923078
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Entry
102923078 CDS
T11302
Symbol
Dot1l
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
pmav Peromyscus maniculatus bairdii (prairie deer mouse)
Pathway
pmav00310
Lysine degradation
pmav01100
Metabolic pathways
pmav05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
pmav00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
102923078 (Dot1l)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
102923078 (Dot1l)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pmav03036
]
102923078 (Dot1l)
Enzymes [BR:
pmav01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
102923078 (Dot1l)
Chromosome and associated proteins [BR:
pmav03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
102923078 (Dot1l)
HMT complexes
Dot1-containing complex
102923078 (Dot1l)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
102923078
NCBI-ProteinID:
XP_076414953
LinkDB
All DBs
Position
22:complement(3472462..3514191)
Genome browser
AA seq
1740 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNATTPTKVP
ESKAAATEVPADSGAEEEKAGVATVKKPSPSKARKKKLSKKGRKMAGRKRGRPKKMSAAN
AERKSKKSQSTLDLLRSPPAAPPPASPQDSYRAPPSPFYQLPPSTQLHSPNPLLVAPTPP
ALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLGTAQQLFGHCQAQKEE
IHRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQSLRLLRA
RCEELRLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKSQRQQELLQLKSC
VPPDDALSLHLRGKGALGRELEADAGRLRLELDCAKISLPHLSSMSPELSMNGHAASYEL
CNTASRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKIVLR
RHLSQDHAGSSKAAAGEPHPRAEPTKESALPYQSPGLSNSMKLSPQDPLPASPATSPLTS
EKGSEKGGKERAYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPS
PVPQPRDSSSTLEKQIGASAHGAGGGAGGSRSLALAPTGFYTGSVAISGALASSSPAPLA
SGVESAVFDESSGPSSLFATMGSRSTPPQHPPLLPQPRNSGPASPAHQLSASPRLSVTTQ
GPLPDTSKGDLPSDPAFSDPESEAKRRIVFSIAAGSGSKQSPSTRHSPVTSGPRGDCGQS
HGQDSRKRSRRKRASAGTPSLSTGVSPKRRALPTVAGLFTQSSGSPLNLNSMVSNINQPL
EITAISSPESSLKSSPTPYQDHDQPPVLRKERPLGPTNGAHYSPLTSDEEPGSEDEPSSA
RIERKIATISLESKSPPKTLENGGGSVGRKSASSGEPVNSSKWKSTFSPISDLSLAKAVD
SPLQAAGSALSHSPLFSFRPALEEPAAEAKLPSHPRKAFAGSLAAPEGPSPGANPPNGLA
FSGGLAGDLGLHSFNDGAPLSHKGPEVAGLSAPLSFPSQRAKDSAAAEANPFLSRRQPEG
LSSLKGEGSAAKESAEALPLGGPADKVALPHGARAGKGRDRELDFKGGHNLFISAAAVPP
GGLLGGPGLVTVASSAASATPAAQAPRPFLSTFPAGPQFTLGPVSLQANLGSVAGSSVLQ
SLFSTVPAAAAGLVHVSSTATRLTNSHTMGSFSSGVAGGTVGGVFAHAVPSASAHPFGAG
VGSGAVCSSATLGLSPLQAAASTSASSFQAAASVETRPPPPPPLLPPQHLGRPPAGPPVL
HAPPPPNVALPPPPALLTSNSEPVLLQSLASLPANKAFLPPSSAASLQPANASLSVKLAS
LPHKVSRPSFTVHHQPLPRLALAQAAPAAPQASSSGPSAVWVSLGMPPPYAAHLSGVKPR
NT seq
5223 nt
NT seq
+upstream
nt +downstream
nt
atgggcgagaagctggagctgaggctcaagtcgccggtgggcgccgagcccgctgtctac
ccgtggccgctgccggtctacgacaagcaccacgatgctgctcatgagattattgagact
atccggtgggtctgtgaggaaatcccggatctcaagctggccatggagaactacgttctc
atcgactatgacaccaaaagtttcgaaagcatgcagaggctgtgtgacaagtacaaccga
gccatcgacagcatccaccagctgtggaagggcaccacgcagcccatgaagctgaacact
cggccatccaatgggctcctgcggcacatcctgcagcaggtgtacaaccactccgtgacc
gaccccgagaagctcaacaactacgagcccttctccccggaggtgtacggggagacctcc
ttcgacctggtcgcccagatgatcgacgagatcaagatgaccgaggacgacctgtttgta
gacctgggcagtggtgtggggcaggttgtccttcaggttgctgctgccaccaactgtaaa
catcactacggagtggagaaagcggacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaacga
ggtgacttcctctcagaggagtggagggaacggatcgccaacacgagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcggttcgcaaacatg
aaggaaggtggcaggatcgtctcctccaagcccttcgcccctctcaacttcaggatcaac
agcaggaacctgagtgacatcggcaccatcatgcgtgtggtggagctgtcgcccctgaag
ggctccgtgtcgtggactgggaagccggtctcctactacctgcacactattgaccgcacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggagcaggaggcc
gcgcggcgacggcagcagcgggagaacaagagcaacgccaccacccccaccaaggtcccg
gagagcaaggccgcggccaccgaggtccctgcggactctggtgctgaggaagaaaaggca
ggtgtggccactgtcaaaaagccatctccctccaaagcccggaagaagaagctgagcaag
aaaggcaggaagatggctggccggaaacgcgggcggcccaagaaaatgagtgctgccaat
gctgagcgcaagtccaagaagagccaaagcacactggacctcctgcgctccccgcccgca
gccccacccccagcctcaccccaggattcgtacagggcgcctcctagcccattctaccag
ctacctccgagcacgcagctccactcccccaatccgctgctggtggcacccaccccgcct
gcattacagaagcttctagagtccttcaaaatccagtacctccagttcctggcctacacg
aagaccccgcagtacaaggccaacctgcagcagctgctggaccaggagaaggagaagaac
acgcagctgctgggcaccgctcagcagctcttcggtcattgccaagcccagaaggaggag
atccacagactgttccagcagaagctggatgagttgggcgtgaaggcgctgacctacaat
gacctaattcaggcccagaaggagatctctgcccacaaccagcagctgcgggagcagtcg
gagcagctggagaaggacaacagtgaactgcggagccagagcctgcggctgctcagggcc
cggtgcgaggagctgaggctggactggtccacgttgtctctggagaacctgcggaaagag
aagcaggccctgcggagccagatctcggagaagcagagacactgcctggagctgcagatc
agcatcgtggagctggagaagagccagcggcagcaggagctcctgcagttgaagtcctgc
gtgccgcccgacgatgctctgtccctgcatctgcgtggcaagggtgccctgggccgcgag
ctggaggccgatgctgggcggttgcgtctggagctggactgtgccaagatctccctgccg
cacctcagcagcatgagccccgagctctccatgaatggccatgccgccagctacgagctc
tgcaatacagctagtcggccctcgtccaagcagaacaccccccagtacctggcctccccc
ctggaccaggaggtcgtcccctgcacccccagccacagtggccggccccggctagaaaag
ttgtctggcctggctttgccagactatacccggttgtcccctgccaagattgtgttgagg
cggcacctgagccaggaccatgccgggtctagcaaagcagctgccggtgagccgcaccct
cgggcggagcccaccaaggaaagcgcccttccctaccagagccctggcttgtccaacagc
atgaagctcagcccccaggatccactgcctgcctccccggcgacctcgccgctcacctca
gagaagggcagtgagaagggcgggaaggagcgtgcctacagcagccacggggagacgatc
accagcctgcccgtcagcattccactcagcacggtgcagcccaacaagctgcccgtcagc
atcccgctggctagcgtggtgctgcccagccgcgccgagagggcgaggagcactcccagc
cctgtgccacagccccgagactcctcatccacacttgaaaagcagattggtgcttctgcc
catggtgcaggaggcggtgcaggagggagcaggagcctcgccctggcgcccacaggcttc
tacacgggctcggtggccatcagcggggccctggccagcagcagcccagcgcctctggcc
tctggagtggaatctgctgttttcgacgagtcctccggacccagcagcctctttgccacc
atggggtctcgcagcacaccgccgcagcacccccctctgctgccgcagccccgcaactcc
ggccccgcctctcctgcccaccagctctcagccagtccccgcctgagtgtgacgacccag
ggtccgctgcccgacaccagcaagggggatctcccttccgaccctgccttctccgacccg
gagagcgaagccaagaggaggattgtgttcagcattgcggccggttccggctctaagcag
tcgccttccaccaggcacagccccgtgacctctggcccccgtggggactgtggtcagagc
catgggcaggacagccggaagcgcagcagacggaagcgtgcgtcagctggaacccccagc
ctcagcacgggtgtgtcccccaagcgccgggctctgccaactgtcgctggcctcttcaca
cagtcctcggggtctcccctcaacctcaactccatggtcagcaacatcaatcagcccctg
gagatcacagccatctcatcccctgagagctccctgaagagttcccccaccccctaccag
gaccacgatcagcccccagtgctcaggaaggagcggcccctgggcccgaccaatggagcc
cattactcaccgctcacctcagatgaggagccaggctctgaggacgagcccagcagtgcc
cgaattgaaagaaaaattgcaacaatctccttagaaagcaaatctcccccgaagacgctg
gaaaatggtggtggctcggtgggaaggaagtcggcctcctcgggcgagcctgtcaacagc
agcaagtggaagtccaccttctcgcccatctccgacctcagcttggccaaggccgtggac
agtccgctgcaggctgctggctccgcgctcagccacagccccctgttctccttccggccg
gcgctcgaggagcccgctgcggaggccaagctccccagccacccgaggaaggccttcgcc
ggctccctggccgcgcccgagggccccagccctggcgccaaccctcccaacggcctggcc
ttcagcgggggcctcgccggggacctcggtttacacagcttcaacgacggtgctcccctc
tcccacaagggccccgaggtggccggcctgagcgcccccctgagcttcccgtcccagcgg
gccaaggacagcgccgccgccgaggccaaccccttcctcagccggcggcagcccgagggc
ctgagcagcctgaagggcgagggcagcgcggccaaggagtcggccgaggccctgcccctg
ggcggcccggcggacaaggtggccctgcctcatggcgccagggccggcaagggccgtgac
cgcgagctggacttcaagggcggccacaacctcttcatctctgccgccgccgtgcctccg
ggcggcctcctcggtggccccggcctggtcactgtggcttcctcggcggccagtgcgaca
cccgctgcccaggctccccggcccttcctgagcaccttccccgcggggccgcagttcacg
ctgggccccgtgtccctgcaggccaacctgggctccgtggccggctcctccgtgctgcag
tccttgttcagcaccgtgccggccgccgccgcaggcctggtgcacgtgtcgtccaccgcg
acccggctcaccaactcgcacaccatgggcagcttctcctccggggtggccggcggcacc
gttggaggtgtctttgcccacgcggtgccttctgcctctgctcacccgtttggagctggt
gtcggcagcggggctgtgtgtagcagcgccacgctgggcctgagcccgctgcaggcggcg
gccagcacctcggcttcttcctttcaggccgcggcttcggtcgagactcggccgccccct
ccgcctcccctccttcctcctcagcacctgggcaggccccctgcggggcctcccgtcctc
cacgcacccccccctcctaacgtggccttgcctcctccacctgcgctgctgacttctaac
tcggagccggtgcttctgcagagcctggcctccctcccggctaacaaagctttcttaccc
ccctcctctgccgcctctctgcagcctgctaacgcctctctgtctgtcaagctcgcctcc
ctcccacacaaggtctcccgcccctccttcacggtgcaccaccagcccctgccccggctg
gccctggcgcaggccgcgcccgccgccccgcaggccagctcctcggggccatctgctgtg
tgggtttcccttggcatgccgcctccttatgccgcgcacctttcgggggttaagcctcga
taa
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