Planctobacterium marinum: MACH26_12990
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Entry
MACH26_12990 CDS
T09721
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
pmaw
Planctobacterium marinum
Pathway
pmaw00260
Glycine, serine and threonine metabolism
pmaw00261
Monobactam biosynthesis
pmaw00270
Cysteine and methionine metabolism
pmaw00300
Lysine biosynthesis
pmaw01100
Metabolic pathways
pmaw01110
Biosynthesis of secondary metabolites
pmaw01120
Microbial metabolism in diverse environments
pmaw01230
Biosynthesis of amino acids
Module
pmaw_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
pmaw_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
pmaw00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
MACH26_12990 (thrA)
00270 Cysteine and methionine metabolism
MACH26_12990 (thrA)
00300 Lysine biosynthesis
MACH26_12990 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
MACH26_12990 (thrA)
Enzymes [BR:
pmaw01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
MACH26_12990 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
MACH26_12990 (thrA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
SIR4_SID
Motif
Other DBs
NCBI-ProteinID:
BDX05778
UniProt:
A0AA48KPS9
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All DBs
Position
1480769..1483231
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AA seq
820 aa
AA seq
DB search
MKVLKFGGSSLADAVRYLSVRDISLQAYKETGAAVVLSAPKGVTNNLEALCQKAEQGENY
EVEFAALKQTLTSIAAELNDTLDNFNHDALSQLITEKLNGLVKHLQGIALLNASPASITA
QILSLGEYVSVNIFSQILTAGGVKNQIIDPVEYVVAEGDYLDSIADLSASRARFADLVVE
KDCLLIMPGFAAANEAGEKVTLGRNGSDYSAAILAACIDAECCEIWTDVDGVYNADPRQV
DGAVLLDKLTYQEAMELSYFGAKVLHPKTIGPIAQYSIPCLIRNTLNPAAPGTLISHEAS
EKWVQVKGISLLENMSMFNISGPGMKGMVGMAARVFEVISNANISISLITQSSSEYSISF
CIQAKDQERARNVLEDAFALEIDNHLLEPIQTKENLAIVTLVGDGMRHTKGLAARFFSSL
AQARVNNVAIAQGSSERSISTVIEARKAKKAVKVIHQNFFSNLHTIDAFLVGCGTVGAEL
LNQISKQQAALLKRDISLRVYGIANSRNLLLREAGIDLANGWREELEASEESLDVRTLQR
FAHDNSLVNPVIIDCTTSDDIAEQYIDFMEAGFHVVTPNKKANTAEIGFYRKLREVARLN
NRQFLYETTVGAGLPVIDNLQNLIYAGDELQQFEGILSGSLSFIFGKLDEGLSISQATKI
AMENGFTEPDPRDDLSGMDVARKLLIMAREAGLELELSDISIESVIPESFDASGSIEEFV
AKLPELDAHFAKLVGDAAAEGKVLRYVGTIKNGECAVKVLPVDAQHPLYTIKDGENALAI
HSEYYQPIPFVIRGYGAGAAVTAAGVFADVLRTMPWAGKH
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgaaagtattgaagtttggcggatcttcactggctgatgcagtcaggtatctgagtgtt
cgggatatcagtttacaagcctacaaggaaactggtgcggcagtggtgttatctgcaccg
aagggggtcactaataacctggaagccttgtgccagaaggcggagcagggcgaaaattac
gaagtggaatttgccgctctcaaacaaaccctcaccagcattgccgccgaactcaatgac
accttagataacttcaatcacgatgcccttagtcaacttattaccgaaaagctcaacggc
ctggtgaagcacctgcaaggtattgctttgctcaacgccagtcctgcctcgattaccgca
caaatcttaagtctgggcgaatatgttagcgtcaatatctttagtcagatattgactgct
ggcggtgtcaaaaaccaaatcatcgacccggtggaatacgttgttgccgaaggcgattac
ttagattccattgccgatttaagtgccagtcgtgcccgctttgccgatttagtggtggaa
aaagactgcttattgataatgccaggctttgctgcggcaaacgaagcgggtgaaaaagtg
acgttaggccgaaatggctcagattattccgctgcgattttagcggcttgtattgatgcg
gagtgctgcgaaatctggaccgatgtcgatggtgtgtataacgccgatccacgccaggtg
gatggtgctgtattgctggacaagctcacttatcaggaggccatggagctttcgtacttc
ggtgcaaaggtactgcatcctaaaactattggccctatcgctcagtattccattccttgt
ttgatccgcaatactttgaatcccgcggcaccgggcacgcttatcagccatgaagctagc
gaaaagtgggtgcaggttaaaggtatctccttgctggaaaacatgtccatgttcaatatc
tccggtccgggcatgaaaggcatggtgggtatggctgccagagtatttgaggtgatctca
aatgcaaatatatcaattagcctgatcacccagtcatcgtccgagtattccatcagtttc
tgtattcaggctaaagatcaggaacgtgcgcgtaatgtattggaagatgcctttgcactg
gaaattgacaaccacttgttagagccaattcaaactaaagagaatctggccattgtaacc
ttggtgggggatggtatgcgtcatacaaaagggttggctgcacgcttctttagctcacta
gcccaggcgcgagtgaataatgtcgccattgcgcagggttcctcagaacgttctatttca
actgtcattgaagcccgcaaggcgaaaaaagcggttaaggtaatccatcagaattttttc
tccaacctccacaccattgacgcttttttggtggggtgtggcaccgtgggcgcagaactc
cttaaccagatcagtaaacaacaagctgcattgctaaagcgtgatatcagtttgcgcgtg
tatggcatcgccaacagtcgtaatttgttattgcgggaagccggtatcgatttagccaat
ggctggcgagaagagttagaagccagcgaagaatcgctggatgtacgcaccttgcagcgc
ttcgctcacgataacagcttggttaacccggtaatcattgattgtaccaccagtgatgac
attgctgagcaatacatcgattttatggaagcgggtttccacgtggttacgcctaataaa
aaagcgaataccgcggaaatcggtttttatcgcaagctgcgtgaagtggcgcggcttaac
aatcgccagtttctctatgaaacaaccgtcggtgctggtttgccggttatcgataacctg
caaaacctgatctatgccggagacgagttacaacagtttgaaggcattttatctggctcg
ctgtcttttatttttggcaagctggacgaaggtttgagcatttctcaggctaccaaaatc
gccatggaaaatggttttactgagccagaccccagagatgatctcagtggtatggacgta
gcgcgtaagctattgattatggcccgtgaagcaggattggaactggaactttcagatata
agtattgagtcggtgatccctgagtcattcgatgcctctggttccatcgaggagtttgtt
gctaaattgcccgagctagacgcgcattttgcaaagctggtgggggatgccgccgccgaa
ggtaaagtattgcgttatgtgggtaccattaaaaacggtgaatgtgcggtaaaagtattg
cctgttgatgctcagcaccctttgtacaccattaaagatggtgaaaacgcactggctatt
cacagtgaatattatcagcccataccctttgtaattagaggttatggtgccggtgcggct
gtgaccgctgctggtgttttcgctgatgttttgcgcaccatgccgtgggctggaaaacac
taa
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