Poecilia mexicana (shortfin molly): 106905750 Help Entry 106905750         CDS       T08022                                  Name (RefSeq) obscurin-like isoform X1   KO K17531   obscurin-RhoGEF [EC:2.7.11.1] Organism pmei  Poecilia mexicana (shortfin molly) Pathway pmei04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:pmei00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     106905750  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pmei01001]     106905750   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pmei04131]     106905750 Enzymes [BR:pmei01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      106905750 Protein kinases [BR:pmei01001]  Serine/threonine kinases: CAMK group   Trio family [OT]    106905750 Membrane trafficking [BR:pmei04131]  Others   Rho GTPase associated proteins    Rho guanine nucleotide exchange factors (GEFs)     106905750 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  I-set Ig_3 ig Ig_2 V-set Pkinase PK_Tyr_Ser-Thr Ig_5 Ig_4 Izumo-Ig SOS1_NGEF_PH RhoGEF Ig_6 C2-set_2 Kdo Sp38 ABC1 fn3 IQ PH IQ_SEC7_PH RIO1 Sgo0707_N2 APH Motif Other DBs NCBI-GeneID:  106905750 NCBI-ProteinID:  XP_014826215 LinkDB All DBs Position Unknown AA seq 6006 aa AA seqDB search MGDNKTGGIVAAAMNRLKVVKGLEDVEVSECESCSFEVTLNLAYIEGVWIRDGMQVKSKP SCRISTHGKKHCLILNRVALGDAGLYCFRASEVETSGRLIVRARDIYIVKELEDVDTLER QPVSFICEVNQVDVDGRWYRDDCRIRPGDNIKIRHQGKTHALLFKSVRPEHAGEIRFTAE RVSSYATLAVKELPVQIARPLRVKIAMYRHRGLLECQVSRPNAQVRWYKNRKELLPCKKY QLISQDVYRQLTIEDVRSSDEDTYTCDAGDDKTSCQLLVEEQAISIVRGMKSLEVMEPKP ALFQVETSLKSGRPPKWTLNSEVLEHSAGVNIDRQGNLHSLCFTSTDSSMSGPVVFVAGK SRSTAQLSVKERPLEVVQHLDDVEARESSSVSLCCEFAPSPRVVRWFKGHTALKISNKYT MKREGKRVELIIHGLTGTDAGQYRCMAGGSQSTAQVKVEAKTLKLVKHLEPADIEEDGTA TFSCELNYVVANAEWLVNNVRLSASAINRIQHMGTMHSLVMQKLRPQESRVTFKAGLLNE TTILKVKERPAVFLRSLEDVVGEEQGEVCLQCEISKDSVTPLWRKDGTVLTSDDKHEFVQ CGKSRALIIHSLSKNDAGQYTCDLGTSQSKAKVTVHDLHVTIVQRIKTVSVLESENCTFE CLLSHELDDEPIWTINGQVVVTNSRIQLVHNNRIYKMGIRDVVLSDAGDVVFTIKDLSCR TMLFVKEKPVHIFRDLLNVKAVPGEDAELSCEITKPEATIRWLKDGRPIRQSPKYEMSIE KNLARLVIKNASIRDSGEYCCEADGVASRAKVEIRELQHTFARELRDTLGEEKGKVTLEC ETRRPAKRATWLKGMAELRPGKKYVIKQRGVVLSLTITCLEKTDTDIYVCDVGTMQSRAQ LTVQGQKVIILDELEDVECLEGDTVTFRCRICPDNYWGVKWYLDETLLYTNELNEIQVTP GGFHTLTFRQLARKDTGTISFVAGDKRSYASLLVRERRPTIIKSLEDCEAFEGGGLVLSC VTSKPCHILWYKDGCLMWHSSRYFTTHSGCEARLTIREVSNSDAGVYECSAGSVTTTAVV TVKAIPAEFTQPLHAVEAKEGEAVTLTCEYSLPGVQFHWRKGFENIRPGEKYVMKQRKTI ISLTIRALLPEDSGEYTCHCRQHQTTASLKVHAIPITFVQKLKNLQAEEGSSVILRCEIS KPGIPVEWRKEHELLRNGVKFQMRKRETTLELLIWKPAPEDSGVYSCECADQMTSATVKI TALPVTFKQKLRNVLIEEGNTATFRCELSKPGQTVEWRKSRDRVIRNGEKYHVRQRDTLT ELRIIDVSPEDSDIYTCICGSIETTATLTVNAIPVTFKQKLKNQQVEEGHNITLQCEISK AGVPVEWRLGGEQLENGEKYQIKQRDSTLELTIRDAVPEDSGIYTCVCREQKTKATVKVI AVPATFKVSMKSQEVAEGNSVTLQCELSKKGVPIQWLKEGQVLSEELGRNKYQIKVEGRK ASMTIVNAQPDDAGKYSCVTGDEKTTAEIRVKALPVTFKQELQRLSVKEGECGVFCCELS KSGAAVEWRKGRVILKPGEKYEMKQEGHLTKLIINNVEESDAGKYTCKTKHSQSSAELRV RESPERRRQRDLPPRFKLPLVNQEVTEGNAVALHCELNKPANSVEWRRGGQLLRNGDKYQ MRKKDLQVEMKITDLTVEDSGDYTCVCGEERTTAQITVNERPIKFIQDLKNIQVQEGSGV ALCCELSKPGFPVQWKKGDVVLTSGEKYQIRQNGSKPELLIRKSLPEDSGSYSCICDDVK TTASVAITAIPVIFKQKLKNQEAVEDGCLTLRCELSKPGQAIEWRRDAQLLKDGEKYQMK QEGRAAEMLIRTVTLADAGEYSCCAGTAVTSADIKVRALPVTFKKEVENLEVKEGDSAAF CCELSKPGAPVDWRKGRVILKAGYKYEMKQERGLTKLIVNNVEENDAGKYTCKTEDSQST AELTVKAPPVTFKTKLRNQQVEEENNVTLSCELSKPGLAVEWAKGKELLKSDFKYQIKNR NSIMELTIKNTQLEDSGLYSCMCGDVKTTAHVTITPIPLTFKLGLKNQEAPEGGKVCLRC ELSRAGVPVQWWKGEDQLYHGGRFQMTQRGNMAEMTIRNIQPEDVGEYSCVFGGQKTTAE VNVRAAASVYFEKELESQVVTEGKSVLMSCEVSSANVPVTWKKDGTVVEDGEHYIVRKKG PLHTLEIKKLQLADAGEYCCITRGKKTTAKLIVRERVKIVKELQDLTVTAGEDAVFVCEL THADVSEGVWWLGSSPLQKNEMNQMTCRGRQHRLVLTMTTPEETGNVAFVVGEERTSAKL LVLPKPKVLFEEKPKDTVIMEGETAFLSCATSDCITMVTWKRNHVPLRSGHKYEMRKEGK VNLLLIHDVEPQDTGIYSCDTGDVQSSFKLTVTELPPYFQEELQSVEAEEGGSACLYCEI SKLGVPIQWKKDRLPIRAGRKYEVRQDGCFLQLYIKDLKPEDSGSYTCQAGSAETSATVS VRETPPFFKKELRSLEAEEGGAAFLQCELSKPGLSVQWKRNRLPLRASRKYDIKQDGCLF QLHINDLNPDDSGNYSCQAGNTETTANVTVRELPAFFRKDLQNIKADEGDTASLFCEVSK PGVSVQWKKNNVPLRVNKKYEMKQEGCFLQLNIKEIKPEDSGCYTCQAGEAETSATVSVK ELPPFFKENLKNVTIEEGGTASLCCEVSKPGLSIQWKKNRLPLRANRKYEMKHDGCFLQL YIKDLTPEDSGTYSCQAGAAEATATVTVKELPPFFKKELVCMEADEGGAASLCCEVSKPG ASVQWKKNKMPLRASKKYEMKREGSILYLHIKDLKPEDSGSYSCQAGNAETTATLSVKER PVYFIKELQNMNAEVGDMISLCCELSKPGVSVLWKKNKLPLRASMKHEMKQNGRLYQLDI KDLKLEDGGSYTCQAGSGESTANVAVKELASLFIKELQSVEAGVGSAASLSCELSKPGVA FLWKKDNLPLRAGEKYEMKQDGCFLQLNIRKISSEDSGSYSCHAGNAETSATVQIKAPTP PSEEKSRTASAQMKSTIPKPAPASENEKPKLPDPNQIPPEPKKRTNRKASITSVEKDTEQ VFGIKVSVQNENNEVQEGVQHKRSPVENLDVAQNGTKVERSEDKGSEVHKKEVKIVQLPE KDYKAGRRIEKPASPLGTKNDLMEKRQPEGNVGKFVKVIPPVNQSERLVGNKVVELKETE KGCETEKGLKQQENTSEEANEVKQKIAQEPTTIWRNSQDEKHVQEQLNGKEIKTDVKPSK HKGEVGKTEEETLKPPVRSKAKVAYGEQSLKSIMNQTEETIPRLIKTSLKDFEDHKERQN GQEFTEKVLTQTPRANQQSIEEPEKADEILQFAPPKPPERRKSKIKIGLEIHESRDTETD QDDVQPKSVGVKSPEEKTDKQLKNPLKKDVEEILKLEGSKSITTDSEAEDKLKQPVKQSV KPIKKEPEIKLAVEPIRRVEETQSTKMEDDIALLYISEEETFSEALTELPPNHFQTAGPE RQTGQQLIQEIQPPEPSPLETDINIEDEPEMQEAAIKIQAAFKGYKARKDMRPVFKEVFK NQNTDLHGTLTLKCVVDGRPSTVRWLKNGQHVINDPRCRVETTENGECTLVVKKLNSSDS GVYTCEVANKFGVTSYNGNITVVKTVQPVPAVQKPVHPPLAAITPLQLAPQKPDTQDVTQ TQSLTQSQAELAPIADAENYVESVNVSLWDAYILTEQNNQTLLEERRSSLIAVSSLSSPS EYDTAPDIMEPVETIPVAPREVPKPADTMQPKDNNEETAAPKPPMKLLNVKGPHDIKLRT ASPKHHRSHTPLTSTVSGSESEGEEDRREIFEIYVARADCSPNIGSKDSFILKEGQFVEV LDSVHPDRWLVRTKPTKTNPSRQGWLCPAYLEKKRKETFPQRRVAQEDLDGIGSTGEEYR RELSQLIQGLIDGEEEFVKAMKMFITHQLNHLDCSHHVPINILNQKEIIFRNIKDIVGLH ERSILPGLRGCVTDDDVAMYLIKHAEHFEKYLHYMVGQAQAEACVSDKAVQQYFKEIAAP EKPGDVPIMDALTFLQQPVERIQTYQALLKELIKNKAKSGQSCYLLEDAFSVVSCLPWRS DNLHRVSLIENYPAPLTALGEPVRQGVFTVWEESPEVKTTSRGHQRQVFLFKECIVLCRV KRDGSMNQDTYSFKNKMKLNDVEIKETVAGEDRSWGLWHEHRGSIRRYTLQSNSTLVKLS WLKDLKELQQCSSLSNNCPPVFESLLCDCSTQIGQTIKLTCRVLGFPKPVVSWIKDGLPL EDDPRHIISADRSGTCSLVLDCLTAEDSGQYMCYATSSMGNAGTLAKVVVQAPPRFVSRL ESACLIDGEEIQFSCSTLTTPLPRIRWLKDGKELTDSNKYSIVNDARSGILSLTVIGATE ADIGQYECELWNELGCVKCKAGLCPAFVPPAESESDQSKDLPVKEADSEAWSTAFVKKWL QTDFSPSSIANTQFPPGSSEQYSTVVDVHPSAVQQSSCYLEEEEEIYISEALHEITDGPP SVQVPAEDLCVEPGQPATFMAIITGRPTPKVQWYKDREPLASSENVKIVQHGARCSLTIL CPEGEDSGIYTCFAHNDSGQVSCEAQLTVEEGLLDPQEREVELGKRRRLFSVYDVHEEIG RGTFGVVKRVIHRRTGEVFSAKFLPLRSSSRTRAFQERDLLSRLAHPRVACLLDFFCTRR TLVLITEICCSHGLLDHLLMRGSVSEKEVQFYVQQILEGVCHIHSMNIMHLDIKPENILM VYPPKDEIKICDFGFCQEIDTSRHQYSVLGTPEFVAPEIVHQEPVTVATDIWAVGVITFL CLVCRCPFVGETDRATLLRVGEATLNWDAPDIVCRSPEARNFLHTVLQPDPETRPSAFEC LSHEWLQDGNAGEDTDEINTRSLKDFISKRKWQRSLTSIGSVLTLRPIPELLDAPLRETS VAVPREPQEHSSTSLSSGSSSEYDEADSWDFFQHCSQTEEEEDTEEEYDPLTERAQILEP YPKCLLSLQEDVGAFGEDEDGEMGERRSVTERSMSRASIASSTTTTDQQTPQRERRFSKD SNRSLYLSDGDEGSGSDGGRIPRGSVIRSTFYNSSQQLSPLSARHMTLRDKFQAKKQERG RKPLRRSFSGRLNEPLIEYVEDEPESNRGQRRGSVQPSMQKSSSFDDGVGFSHTNVPPHR RSRSLDEYSRRSPSSASHESAREEEASHSTKEEITHGEAAGRNSLIFQKAPKVSGRRGSV ALTQGVFSGSSVPSEFLAGGRMRSRLGQDQTEGDTLTSSQGSLAESFILEHGGSESSSRI GSFDELSHGHVGRRYRSGGSDENDEHSEPLITPSPTPFQEIKPRSSRPQPPPRNRTRSNP NLSTISKGQPERPSMPSPSPSLCSLGTPERPPRARDKKEGAMLQRHASAPALEARPPTGK SPKLGLLRIFRRQSWTGHSYTQLESTELGPTLGEIMKPDTPTMSLRKKMRASASSLTKLF SRSSSKENVSKGGPIVKGSTAIPAEREQSSGLETPKKRNSKLLSSFKIPPFKKIKVHPSK AEVLQLDGGGVLLVWRPVQSDDPVTYCVQYCSEGGEWTILSDEVADSCYVVKDLPKGASY VFRVGCVTRTGAGPFSEASAPIVMSTHPEDIRIPLIQTDSIGSKVPGSEHQTVNRNYSFL SEINRGRFSVINLCRDVETSQVFAAKITPYQAEQRQLVLREYQLLRRLHHPHLVQLYAAF ITPLYVLLVEELCPGKELLHSLAARDLYAESNVAELLHQIVSAADYLHSRRVIHLDLKSD NMLVDDGNHLKIIDFGSAQSFVPGQPLNIEHIHGFADSKDCCRKVYIVLPKAPEILEGQG VGPETDIWAVGVLSFIMLSADSPFYAEHSWEQDKNIKKGKIQFGRCYPGLSEGALNFMKN SLNNKSWGRPTAAECLQNPWLRAHRAPHKVRPSKVCFSTDKLRAFLKQKEEKRDQVCTKH QGPFFQ NT seq 18021 nt NT seq  +upstreamnt  +downstreamnt atgggggacaataaaactggagggattgttgcagctgcaatgaaccgactgaaagtggtg aaaggattggaggatgtggaggtgtccgagtgtgagagttgctcctttgaggtgactctt aacttggcttacattgaaggcgtttggatcagggatgggatgcaggttaagtcgaaacca agttgtcgcatcagcacgcacgggaagaaacactgcctcatcctgaaccgagtggctttg ggagatgctggtttatactgtttccgggccagtgaggttgagacatcaggcagactcatt gttagagctagagacatatatattgtgaaagagctggaggatgtggatacgcttgagcgt caacccgttagttttatatgtgaagtcaatcaggtggatgtggatggtcggtggtatcgt gatgactgcagaatccgacctggagacaacatcaagataagacatcagggtaaaactcat gctttgctcttcaagtctgtcagaccagaacatgcaggtgaaatcagattcactgcagag cgagtgtcatcttacgccactcttgcagtaaaagagctgccagtccaaatagctcgacca ctgagggtcaaaattgccatgtatcgccacagaggtctactagagtgccaggtgtcacgg cctaatgctcaggtcagatggtacaagaacaggaaggagctcctgccctgcaagaagtat cagctaatcagccaggatgtctacaggcagctgaccatcgaagatgttcgctcttcagat gaagacacctacacatgtgatgcaggggatgacaaaacttcatgtcaacttttagtggag gagcaggccatcagcatagtgcgggggatgaaatctttggaggtgatggagccgaagcct gcactattccaggtagaaaccagtctaaagtctgggaggcccccaaagtggaccctaaac agtgaggtcctggagcactctgcaggagtgaacattgaccggcaggggaacctccacagt ctctgtttcacaagcacagacagctccatgtcagggcctgtggtgtttgtggctgggaag agccgttccaccgctcagctttctgtgaaggagcgacctcttgaggttgttcagcactta gatgatgtggaggcaagggagagcagctctgtgagtttgtgctgtgagtttgccccgtct ccccgagtcgtgcggtggtttaaaggacacaccgctctgaagatctcgaacaaatacacc atgaagagagaggggaaacgagtggaactgatcattcacggcctgacggggactgacgca ggacagtaccgctgcatggctggaggttcacaaagcacagcacaggtcaaggttgaagca aaaacattgaagctggtcaagcatcttgagcctgctgacattgaggaagatggcactgcc actttttcatgtgagctcaactatgttgttgccaatgccgagtggctggttaacaacgtc cgcctcagcgctagcgccatcaaccggatccagcacatgggcacaatgcacagcctcgtg atgcaaaagcttagaccacaggagagcagggtcacatttaaagcaggccttctcaatgag acaaccatcttaaaggttaaagagcgcccggcagtgtttcttaggtctttggaggatgtc gttggagaagagcaaggggaggtctgcttgcagtgtgaaatctctaaagattcagtaacg cctctctggaggaaggatggtactgtcctgacatctgatgataaacatgagtttgtacag tgcgggaagtccagggcattgatcatccactcactaagcaagaacgatgctggacagtac acttgtgacctgggcaccagtcagtccaaggctaaagttacagtacatgatctacatgtt accattgttcagcggataaagacagtatctgttctggagagtgaaaactgtacttttgag tgccttctctctcatgaactggatgatgaacccatctggaccatcaacggtcaggtggtg gttaccaacagtcgcattcagcttgtccacaacaatcgcatctataagatggggattaga gatgtcgtactttctgacgctggtgacgttgtcttcacaattaaagacctgagttgtaga accatgttatttgtgaaagagaagcctgtgcacatcttcagggacctgctcaatgtaaag gctgtacctggggaggacgctgagctgagctgtgaaatcaccaaaccagaagccaccatt cggtggctgaaagatggacgtcctatcaggcagagccctaaatatgagatgagcattgag aagaacctggcacgcctggtgatcaagaatgcctccatcagagactctggtgaatactgc tgcgaggctgatggtgttgcatcccgagccaaggtggagatcagagaacttcagcacact tttgcaagggagttgagagatactctaggagaagaaaagggtaaagtgacactggagtgt gaaaccaggcggcctgccaagcgtgcgacatggctaaagggcatggcggagctcagacct gggaagaagtacgtcatcaaacagaggggagtggttctatcccttaccatcacctgccta gagaaaacagacacggatatttatgtgtgcgatgttggtaccatgcagagccgggcacaa cttactgtgcagggtcagaaggtgataatcttggatgaattagaagatgtggagtgcctc gaaggtgacactgtaacattcaggtgtcgaatttgtcccgataactattggggggtcaag tggtatctggacgagactctgctttatactaatgagctcaatgagatccaggtgacaccg ggaggtttccacacccttacatttagacaacttgcccgtaaagacactggtactatttcg tttgtagcaggggacaaaagatcttatgcctcactgctagttagagagaggcgtcctacc atcatcaaatcactggaagactgtgaggcttttgagggaggaggcttagttttgtcttgt gtgacttccaagccatgtcacatcttgtggtacaaagatggctgcctgatgtggcactcc tccagatacttcaccacccattctggctgtgaagcccgactgaccattcgagaggtcagc aacagtgatgctggagtgtacgagtgcagcgctggctcagtcacaaccacagctgtcgtt actgtcaaagccatcccagcagagttcacccagcctctgcatgctgtggaggccaaagaa ggagaggctgttacacttacctgtgaatattctttacctggagtccagtttcattggagg aaaggttttgagaacatccgacctggagaaaagtatgtcatgaagcagaggaaaaccatc atctctctcaccatcagagcacttctgcctgaggactcaggagagtacacatgccattgc aggcaacaccagacgacagccagtctcaaagtgcatgctattcccattacattcgttcag aaactgaagaacctacaagctgaggagggcagcagtgtgatattgcgctgtgaaatttct aagcctggaatcccggtagaatggaggaaggagcacgaactgctgaggaatggtgtcaag ttccagatgaggaaaagggagaccactttggagctcctgatttggaaacctgcacctgag gacagtggggtgtacagctgtgagtgtgctgatcagatgacatctgccacagtcaagatc accgctctgccagtcaccttcaaacagaagctgaggaacgtgttgattgaggagggcaac accgccacatttcgttgtgaactctccaagcctggtcaaactgtagagtggaggaaaagt cgagacagagtcatcaggaatggagaaaagtatcacgtgcgacagagagacactcttact gaactcaggatcattgatgtgtctcctgaagacagtgatatctacacttgcatctgtgga agcattgagacaacagccaccctgactgtaaatgccattcctgtgaccttcaagcaaaag ctgaagaaccagcaagtggaagaaggacacaacatcacactgcagtgtgagatttcaaaa gctggtgtcccagttgagtggaggcttggaggagagcagttggagaatggagagaagtac cagataaagcagagggattccaccctggaactgaccatcagggatgctgtgcccgaggac agcggcatctacacctgtgtgtgcagagagcagaagacaaaggccactgtaaaagtcatt gcggttcctgccacatttaaagtgagcatgaagagccaagaggtggcagaaggaaatagc gtgactttacaatgtgagctgtcaaagaaaggagttcctattcagtggctgaaagagggt caggtgctgtctgaagagttaggccgtaataaataccagataaaggttgaaggaaggaaa gcttcaatgactattgtcaacgcacaaccagatgatgcagggaagtacagctgtgttact ggtgatgagaaaaccacagcggaaatcagagtcaaagcgcttcctgtcacattcaaacaa gaactccagcgcctgtcggtcaaagaaggagagtgtggagttttctgctgtgagctctct aaatctggagctgctgtggagtggagaaaaggcagagtgatcctgaaaccaggagagaaa tatgaaatgaagcaggagggccatctaaccaaactcattataaacaacgtggaggaaagc gatgctggcaaatacacctgcaagactaaacacagccaatccagtgctgagctcagagtg cgagaatcacctgagcgcagacgtcaaagagatctccctccacgcttcaagttaccatta gttaaccaggaggtcacagagggcaatgctgtggctctgcactgtgagctcaacaagcct gctaactctgtggagtggaggagaggaggacagctactcaggaatggagacaagtaccag atgaggaaaaaagacctgcaggtggaaatgaagatcacagacctcacagtggaggattct ggagattacacctgtgtatgtggggaagaaaggacaacagctcagatcacagtgaatgaa aggcccattaaattcattcaagatctgaagaatattcaagtacaggagggaagcggcgtg gcactctgttgtgagctctccaaaccgggcttcccagtgcagtggaagaagggtgacgtc gtgctcaccagcggtgagaaataccagatcaggcaaaacggctccaagccagagcttctc atcaggaaaagcctcccagaggacagtggctcttacagttgcatttgtgatgatgtcaaa actacagcaagtgttgcaattactgcaattccagtgatattcaagcaaaaacttaagaac caggaagcagtggaggatggttgtctaacattacgctgcgaactttccaaacctggacaa gcaatagagtggaggagagatgcacaacttctgaaggatggagaaaaataccagatgaag caggagggccgagcagcagagatgctgattagaactgtaactcttgcagatgcaggagaa tacagctgttgtgctgggactgctgtgacttcagctgacatcaaagttagagctcttcct gtgacattcaagaaagaagttgagaatttggaggtgaaggaaggagacagtgcagctttc tgctgcgagctctccaaacccggcgctccggtcgactggagaaaaggcagagtcatcctg aaggctggttacaagtacgagatgaaacaagagagaggtctcaccaagctgatcgtcaac aacgtggaggagaacgatgccggaaaatacacatgcaaaacagaggacagtcaatccacc gctgagctcacagtcaaagctccgcccgtcacattcaaaacaaagctaaggaaccagcag gtggaggaggaaaacaatgtgacgttgagctgtgaactgtcaaagcctggcctcgctgtg gagtgggcaaaagggaaagagctactgaagagtgatttcaagtaccagattaaaaaccga aacagcatcatggagctgaccatcaagaacacccaactggaggacagcgggctctacagt tgtatgtgtggagatgtcaagaccacagcgcatgtcacaattacacccatccctctaaca ttcaaactgggtctgaagaaccaggaggctccggagggagggaaagtgtgtctgcgctgt gagctgtccagggccggggtgcccgtgcagtggtggaaaggggaggaccagctgtaccac ggagggagattccagatgacacagagagggaacatggctgagatgaccatcagaaacata caaccagaggatgttggagaatacagctgcgtatttggaggtcaaaagacaacagctgaa gtcaacgtgagagctgcagcatctgtgtactttgagaaggaactagagagccaagtggtt acggaggggaaatctgtgctcatgtcctgtgaagtttctagtgctaatgttcctgtcact tggaagaaagacggcactgtggtggaagacggagagcattacatagtgagaaaaaaaggc cctttgcacactctggagattaagaaattgcagctggcggatgctggagagtactgctgc atcaccagaggaaagaaaaccactgccaaactgattgtgagggagcgtgtcaagattgtg aaagaactgcaggacctaacagtgacagctggagaagacgctgtgtttgtgtgcgagctg acccatgcagacgtgagcgagggcgtgtggtggcttggttcgagccccctgcagaaaaac gagatgaaccagatgacgtgccgtggccgccagcaccgcctcgtcctcaccatgacaaca ccagaggagaccggcaacgtagcatttgtagttggggaggaaaggacctctgcaaaactg ttggttctccctaagcccaaagttttgtttgaggagaaacccaaagacactgtcatcatg gaaggagagacagctttcctgtcctgtgctacatctgattgcatcaccatggttacctgg aagcgcaaccatgtcccacttcgaagtggtcataaatatgagatgcgcaaggagggtaaa gtcaatctgcttcttatccatgatgtggagccccaagatactggcatatattcctgtgat accggagatgtgcagagcagtttcaagctgactgtaacagaacttcctccatactttcaa gaagagctacaaagtgtagaagctgaagaaggaggctcggcctgcctctactgtgagata tctaaactaggagtgccgattcagtggaaaaaggacaggctgccgataagagccggcagg aagtatgaggtgaggcaagatggctgctttctccagctttacatcaaagatcttaaacct gaggacagcggcagctacacgtgtcaagcagggagtgcagagacaagtgcaactgtgtct gtaagagagacgcctccattcttcaagaaagaattaagaagtttggaggctgaggaagga ggtgcagctttcctgcaatgtgagctatctaaaccagggttgtctgtgcagtggaagaga aacagactgccacttcgggcaagcaggaagtatgacatcaaacaagatggctgcctgttc cagctccacatcaatgacctgaatcctgatgacagtggcaactactcctgtcaagcagga aacacagagacaactgctaatgtgacagtcagagaactcccagcttttttcaggaaggat ctgcagaacataaaggcagacgaaggagatacagcctcacttttctgtgaggtttctaag cctggagtctctgttcagtggaagaagaacaatgtgcctctgagagtcaataagaagtat gaaatgaagcaggaaggctgctttctacagcttaacatcaaggagatcaaaccggaggac agtggctgctacacttgccaagcaggagaggcagagactagtgccactgtctcagtaaaa gaacttcccccgtttttcaaggagaatttgaaaaatgtcaccattgaggagggagggaca gcatccctttgctgtgaggtatccaagcctgggctatcaatacagtggaagaagaacagg ctgccactgagagcaaacaggaagtatgagatgaagcatgatggctgcttcctccaactt tacatcaaggatctcacacctgaggatagtggtacctactcatgtcaagctggagctgca gaggctacagcaactgtgactgtgaaagaacttcctcccttcttcaagaaagagctagta tgcatggaggctgacgaaggtggagcagcgtctttatgctgcgaagtgtctaaacctgga gcgtctgtgcaatggaagaaaaacaagatgccactcagagccagtaagaagtatgagatg aaacgagaaggttccatcctttatctacatatcaaagacctgaaacctgaggacagcggc agctactcgtgtcaagcagggaatgcagagaccactgcaacattatctgtgaaagaacgt cctgtgtactttatcaaggagttacaaaatatgaatgctgaggtaggagacatgatctca ttgtgctgtgaactttccaaacctggagtttcagtgctgtggaagaaaaacaagctgcca ctgagagccagcatgaagcatgagatgaaacaaaatggtcgactctatcagcttgacatc aaagatctcaaacttgaggacggtggcagctacacatgccaagcagggagcggagaaagc actgcaaatgtggcagttaaagaacttgcttcattgttcatcaaagaattacaaagtgta gaggcaggggttggcagtgcagcctcattgtcctgtgagttatccaaacctggagtggct tttctgtggaagaaggataatctgcctctgagagccggcgagaagtatgagatgaaacaa gacggctgtttcctgcagcttaacatcaggaagatcagttcagaggacagtggtagctac tcatgtcacgccggaaatgcagaaacgtctgcaacagtacaaataaaagcaccaacacct ccatcagaggaaaagtctagaacagcatcggcgcagatgaaaagtacgatccctaaacca gctcccgcttcagaaaatgaaaagcccaagcttccagatcccaaccagattcccccagag cccaagaagaggacaaatcggaaagcatctattacttctgtcgaaaaagacacagagcaa gtttttggcataaaggtgtctgtgcagaatgagaataatgaagtccaagagggtgttcaa cataaaagatctccagtagagaacttggatgttgctcagaatggaacaaaagtggagagg agtgaagacaaagggagtgaagtgcacaagaaagaggttaagatagttcagctaccagag aaggattataaggctggtaggaggattgaaaagccagcttcacctctgggtaccaaaaat gatcttatggaaaagagacaaccagaagggaatgtaggaaaatttgttaaagtcatccct ccagtaaatcagtcagaaaggcttgtgggtaacaaagtggttgaactgaaagagacagaa aagggatgtgaaactgaaaaggggttaaaacaacaagaaaacacttcagaagaagcaaat gaagttaaacagaaaatagctcaagaaccaacaacaatttggagaaacagtcaggatgaa aaacatgtacaagagcagcttaatgggaaagaaataaaaacagatgtcaaaccttcaaaa cacaaaggtgaagtaggaaagacagaagaggagactttgaaaccaccagtaagatctaag gcaaaggtagcatatggagagcaatcactcaagtctattatgaatcaaacagaggaaaca attcctcgactgatcaagacttcccttaaagattttgaagatcataaagagagacaaaat gggcaagagttcacagagaaggtattgacacaaacgcccagagcaaaccagcaatcaata gaagagccagaaaaggcagatgaaatccttcagtttgcacctccaaagccacctgagagg agaaagagtaagataaaaataggattggaaatacatgagtcacgggacacagagacggat caagatgatgtacagcctaaaagtgttggagtaaagtcccctgaggagaagacagacaaa caactaaaaaatcctttgaagaaagacgttgaagaaattttaaagttagaaggaagtaag tctatcacgactgatagtgaagcagaagataaacttaagcaaccagtaaaacaatcagta aaaccaattaagaaagaacccgaaattaaactggctgttgagccaataagaagagtggag gaaacacaatcgactaaaatggaagacgacattgctctgctctacatttctgaagaagaa actttctcagaggccttaactgagctccctcctaaccacttccaaactgctggtcccgag agacaaacaggacagcaacttatccaggagatccagccaccagaaccgtctcccctggag actgacatcaacatagaggatgaacccgaaatgcaagaagctgccattaagatccaggca gcattcaaaggctacaaagctcgcaaggacatgcgaccggtctttaaggaggtattcaag aaccagaatacagatcttcatggtacacttacattaaagtgtgttgtggatggaagaccc agcactgtgcgctggttgaaaaatggccaacatgttataaatgatcctcgatgccgggtt gaaacaacagaaaacggagaatgcacactcgtggttaaaaaattgaacagcagtgacagc ggagtttatacctgtgaggtggcaaataagtttggtgtgacctcctacaatggaaacata accgtagtgaagactgtgcaacctgttcctgcagtccagaagcctgtacacccaccacta gcggccataactcctttgcagcttgctccacagaagcctgacacccaggacgtgacacag actcaaagcctgactcagagtcaagcagagctagctccaattgcagatgctgaaaattat gtagaaagtgtgaatgtttccctgtgggatgcttacatcttgacagaacagaacaatcaa acactcctggaagagagaagatcttcactcattgctgtcagctccttgtcaagtccctca gagtatgacacagctccagatataatggagcctgttgagactattccagtggcaccaagg gaagtaccaaaacctgctgacacaatgcagccaaaggataataacgaagaaacagctgct ccgaaacctcctatgaaactgctgaatgttaaaggacctcatgatattaagctaagaaca gcatctccaaagcaccatcgatcccacacgcctttaacaagtactgtgtctggatctgag tcagagggtgaagaggacagacgagagatatttgaaatatatgtagctcgtgccgactgc agtcctaatattggaagtaaggacagttttattctgaaagagggtcagtttgtggaggtc ctggactctgttcatcctgacagatggttggtgaggaccaaaccaaccaaaaccaaccct tctcggcagggatggctgtgtcctgcctatctggaaaagaagagaaaagaaaccttccca caaaggagagttgctcaggaagatctcgatggaattgggtctacaggggaagagtacagg agagaactgagtcagctgatccaaggcttgattgatggagaagaggagtttgtaaaggca atgaagatgtttatcactcaccagctcaaccatctggactgtagccaccatgttcccatt aacatcctcaatcagaaagaaatcatcttcaggaacatcaaagacattgtcggtttacat gaacgttccatcctccctggcctgaggggctgcgttacagatgatgatgttgccatgtat ttaatcaagcacgctgaacattttgaaaagtaccttcactacatggtggggcaagcacaa gcggaggcctgcgtcagtgacaaggctgttcagcaatacttcaaagagatagcagcacct gagaagcctggtgatgtccctattatggatgcccttactttcctgcagcaaccagtagag aggattcaaacctaccaggcgttactgaaggagctgatcaagaacaaagcaaagagtggc cagagctgctaccttttggaggacgccttctccgtggtgtcctgtttgccctggagatca gacaacctgcatcgagtatcactgattgaaaactatccagctcctcttactgctctgggc gagcctgtacgacagggagtcttcacagtgtgggaggaatctccagaagtgaaaacaacc tctagagggcatcagagacaagtgtttctctttaaggaatgcattgtactgtgtagggtg aagagagatggcagcatgaatcaagacacttacagctttaagaacaaaatgaagctgaat gatgtggaaataaaggaaacagtggcaggagaagacaggtcctggggtttgtggcatgag cacagaggctctatacggcgttacactttgcagagcaactccactctggttaagctgtcc tggctgaaagacctgaaggagctgcagcagtgctccagcctcagcaataactgccctcca gtgtttgagtctctgctttgtgattgctcaacacaaattggacagacaatcaaactgacc tgcagagtactgggatttccaaaaccagtggtcagctggatcaaagatggtcttcctttg gaggacgacccacggcacatcatctcagctgaccggtcaggaacatgcagtcttgtcctg gactgccttacagcagaggattctggtcagtacatgtgctatgcaaccagctctatgggc aatgctggcactctggctaaggtggtggtgcaagctccacccagatttgtgagccgacta gaaagtgcgtgtctgattgacggagaggagatccagttttcatgttccactctcacaacc cctttgccaagaatcaggtggttgaaagatggcaaggagctgactgacagcaataaatac tccattgtgaacgacgcccgaagtggaatcttgtctctcacagttatcggagcaacagag gcagatatcggacagtatgagtgtgagctttggaatgaactcggctgtgtcaaatgcaaa gcaggtctttgtcctgcctttgtaccgccagctgaaagtgagagtgaccaatcaaaggac ttacctgtcaaagaagctgactcagaggcctggtccactgcctttgttaagaaatggctg cagactgatttcagcccttcttctattgcaaatacacaatttccccctggatcttctgag caatacagcacggttgtggatgttcacccatctgcagtacagcaatcttcatgttatctg gaagaagaagaagagatctatatttcagaggctttgcacgaaataacagatggtcctcct tcggtccaggttcctgctgaggatctgtgtgtcgaacctgggcaaccagcaacattcatg gccatcatcacaggaagacccacacctaaagtacagtggtacaaggatagggagcccctt gcatccagtgagaatgtgaaaatagtccagcatggtgctcgctgcagcctaaccatattg tgccctgaaggagaggacagtggcatatatacctgcttcgctcacaacgactcaggccaa gtctcctgtgaagctcagctaacggttgaggaaggtctgcttgatcctcaggagagggaa gtggagctggggaagagaaggagattattctcagtctatgatgtccatgaggaaattgga agggggacatttggggtggtgaagcgtgtcatccacagaagaacaggggaagtgttttct gccaaatttctgcctcttcggagcagctctcggaccagggccttccaggagagggatctt ctgtctcgcctcgctcaccccagagtggcctgcttgctggacttcttttgcaccagacgc accctggtgttaatcacagaaatctgctgttctcatggacttctggaccatttattgatg agaggatctgtctcagaaaaagaggttcaattttatgtccaacaaattctagaaggggtt tgtcatattcacagcatgaacatcatgcacctggatatcaaacctgaaaatatattaatg gtgtacccgcccaaagatgagatcaagatctgtgattttggcttctgccaggaaatagac acatcccgacaccagtacagtgtgttgggtaccccagagtttgttgcacctgagattgta catcaagaacctgtcactgtggccacggatatttgggctgtcggtgtcataacatttctg tgtctggtttgccggtgcccctttgtgggcgagactgaccgtgcaacattgctcagggtg ggagaggcaactttaaactgggacgcgccggacatcgtatgcaggagcccagaagccagg aattttctccatacagtccttcagccggatccagagactcgaccatctgcctttgagtgc ttgagtcacgagtggcttcaggatggaaatgcaggggaggacactgatgaaatcaacacg aggagtttgaaagacttcatatctaaaaggaagtggcagcgttctttgacatctatcggg tctgtgctcactctgaggcccatccccgagctgctcgatgctcctcttagagagacgtcg gttgcggtgccccgcgagccgcaggagcacagcagcacctccctgagcagcggctcctca tcggagtatgatgaggccgattcttgggactttttccagcactgcagccagacagaggag gaggaggatacagaagaagagtatgaccccttaacagagagggcacagatcttggagccg tatcctaaatgcctcctaagtttacaggaggatgtaggggcttttggggaggatgaggat ggagaaatgggagaacggaggagtgttaccgagcgcagcatgagcagagcatcgattgcg tcatcaacaacaacaacagaccaacagacacctcagagggaacgacgcttcagcaaggat agcaaccgatctttgtacctctctgacggcgacgagggttcaggaagtgacggaggccgc attcccagaggaagcgtcatccgaagcactttctacaacagctctcaacagctttcccct ctgtctgcgagacacatgactttgagggacaaattccaggcgaaaaagcaggaaagaggc cgtaagcctctcaggaggagcttctcagggcggctcaatgagcctctgattgaatacgtg gaggatgaacccgagagcaaccgtgggcagagacgaggatccgtacagcccagtatgcag aagtcctcttcgtttgatgatggggtgggcttctcccacaccaacgtaccgccacacaga cggagcaggtctcttgacgagtattcccgtcgatctcccagctcagccagccatgaaagc gcacgcgaagaagaggcctctcacagcacgaaggaagaaatcacacatggtgaagcagct gggagaaactcactaattttccagaaagctccaaaggtctcaggacgaagaggctcagtc gctctgacacaaggggtatttagtggatcatctgttccatcggagttccttgctggaggc agaatgagatccaggctgggtcaggaccagactgagggagacacgctgaccagctcccag gggtctctggcagagtctttcattctggagcatggtggatctgagtcttcaagtagaata ggctcctttgatgagctcagtcatggtcatgtcggaaggagataccgatcaggagggagt gatgaaaatgatgaacacagtgaacccctgattacaccctcccctaccccatttcaggaa ataaaacctcgaagttcccgtcctcagcctccaccacgtaatcggacccggtccaatccc aacttgtctacaattagcaaaggtcagccagagaggccctcaatgccgagtcccagtcca agcctctgctctctaggaactcctgagaggcctcccagagcccgggacaagaaagagggc gccatgctccaaaggcatgcatctgctccggctctggaagcgcgcccaccgactggaaag tcccccaaactgggtctcctgaggatcttccgcaggcagtcctggaccggccactcatac acccagctggagagtacggagctggggcccacactgggagagatcatgaagcccgacacg cccactatgtctctgaggaagaagatgagagcttcagcctccagtctgaccaaactgttt tccaggtcctccagtaaggaaaatgtcagtaaaggagggccaatagtaaaaggatccact gccatcccagctgagagggaacagagcagtggtctcgagacccccaaaaagagaaactca aagctcctctcatcttttaaaataccaccattcaaaaagataaaagttcatcccagcaaa gcagaggtgctccagctagacggaggaggagtcctgctggtgtggaggcctgtccagtcc gatgacccggtcacttactgtgtgcagtactgttcagaaggtggcgagtggacaatcctg tcagatgaggtggcagacagctgctacgtagtgaaggatttaccgaaaggggcgtcgtat gtgttcagggtgggctgcgtcaccaggacaggagcaggacctttcagtgaagcttcagct cccattgtcatgtccactcatcctgaagatatccgcattcctctcattcagactgactca atcgggtcaaaagtacctggatcagaacatcaaaccgtaaacaggaactacagcttcctg tctgagatcaacaggggtcgtttcagtgtcataaacctgtgcagggatgtggaaaccagt caggtattcgccgctaagatcactccctaccaggccgagcaaaggcagctggtgctgcgg gagtaccagctgctcaggaggctgcatcacccccacctggttcagctgtacgctgctttc atcacccctctgtatgtgctgctggtggaggagctgtgtcccggcaaggagctgctgcac agtctggctgcaagagacctgtatgcagagagtaatgtggccgagctgctccatcagatt gtcagcgcagcagactacctccacagccgccgggtcatccacctggacctgaagtctgac aacatgctggtggacgatggcaaccacctgaagatcatcgacttcggctcagctcagtcc ttcgtacccggacagcctctcaacatcgagcacattcatggcttcgcagacagcaaagac tgctgcagaaaagtctatattgtccttcctaaagctccagaaatcctggagggtcagggt gtggggccggagactgacatctgggccgttggagtcctgtcctttataatgctgagcgcc gacagtcccttttatgccgaacacagctgggagcaagacaaaaacattaagaaagggaag atccagttcggccgctgttaccctggtctgtcagaaggagctttaaacttcatgaagaac agcctgaataataaatcctgggggagaccaacggcggccgagtgtctccagaacccgtgg ctgcgcgcccatcgggctccacacaaagtccgaccctccaaagtgtgcttctccactgac aagctcagagctttcctcaagcagaaggaggagaaacgagatcaggtgtgcacaaaacat caggggccgttcttccagtga

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