Poecilia mexicana (shortfin molly): 106921054
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Entry
106921054 CDS
T08022
Symbol
brca2
Name
(RefSeq) breast cancer type 2 susceptibility protein
KO
K08775
breast cancer 2 susceptibility protein
Organism
pmei
Poecilia mexicana (shortfin molly)
Pathway
pmei03440
Homologous recombination
pmei03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
pmei00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
106921054 (brca2)
03460 Fanconi anemia pathway
106921054 (brca2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
pmei04121
]
106921054 (brca2)
03036 Chromosome and associated proteins [BR:
pmei03036
]
106921054 (brca2)
03400 DNA repair and recombination proteins [BR:
pmei03400
]
106921054 (brca2)
Ubiquitin system [BR:
pmei04121
]
Ubiquitin ligases (E3)
Multi subunit type E3
BRCC complex
106921054 (brca2)
Chromosome and associated proteins [BR:
pmei03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Other centrosome duplication proteins
106921054 (brca2)
DNA repair and recombination proteins [BR:
pmei03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA complex
106921054 (brca2)
FA (Fanconi anemia) pathway
Downstream FA components
106921054 (brca2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
BRCA-2_helical
BRCA2
BRCA-2_OB3
BRCA-2_OB1
BRCA2DBD_OB2
BRCA2_TR2
Tower
Motif
Other DBs
NCBI-GeneID:
106921054
NCBI-ProteinID:
XP_014847970
Ensembl:
ENSPMEG00000001742
LinkDB
All DBs
Position
Unknown
AA seq
3035 aa
AA seq
DB search
MDSCIKNMYDAFKGEIWKELGPLDPNWFELLTAQASLKEGSVADNDELCANQEGHFKAPL
EKTATESQLFSTPKVFRHSRIVSPDTEDDPSFTAAQEKETLPWMPTQSPCLFQVPKHCVS
NLKCEGVQPQSEESFDLLDSPKKSPATYANHISESLGAQINPDISWTSSLNTPPALPSTL
ILSKTDESPCPVSVTADRKVVFVRKLFPSLSNSSLKTSRTCQGPVFPVTETCSESPLNQS
ESHQQQKVPDALEGEVCIADAPKTFFANSSSALRKVKPDRVKRKQIIQTNVDVCSHEDAS
KSDSAASNEEATADLDSGGLPSTPLVKTGDTAISQWSPLSLSEISSSAVGSNMTLPGDTD
SVQPTRPTSKITDSGFTQKKRKFVYTITTTKSQACGQDFELQTADLSLKISESEQENGKS
FVNIPDKEECQRTKNQRNIVEETINCSLGTKLQDIDMSQLCRDFALDFSQMTDLKTAENT
QRNFSPAACLSVMKQAKQNGKPANFPNDYSCISKNRRIPTSNQPCSISEVTMIDSGFQSG
VADVTHMTSSSFGLPLLENVSQNRPTLSFKTGMHNFPSANGSGKSKFDVEVPVQRSGTGQ
APDHGKEIELHMASISTEELWDKEETVGQNKCSQPQKTPLSLLPAEASGFKTASNKGIHI
SLANLEKAKLFLEATEDKKSSLDNSTKSYHGIIYKTNSIRETTTDTSSNANPPACAGKSF
GNVSSQLTASEKADVTELCTLLEEADSQFEFTQFRSGKKLPNHQDNHNPPHKEDKDLDPA
LLADIDFDDSFSSEGGKQSTVMMNDKVASVLENRTHGEKAKAINQCTGMSDLLKRETPLI
LPGAEDPEAKCLENNKALIHSEAFRTAGGNVLHVSTKCLNKAKALFGDLERNLTDQKPSN
QNGENAAITEQKCNRDSDTFRIPERKKENWDVGTKIENCFSKLEGVVCSNNNVGNRNDTK
SGKNNGIDTIICENGFRKASGKGISISANYMQEADVFFKDCHVMEHKEGKKSFSNFKSPQ
VSISKKSVTGCTKLENVNTAVVSHHTKGLRLNEVERNTKFTAALKNEDGKSFPTSKPFAM
LHPSKSTDLSAFEELCTGDGFCTAAGKNISVSSAAMKKAEFLLNQIHAPEEINKETNEKE
KASKTKCLGDKISNVDTGGFQAVDGKKFAISSAPLKKATLLRESEKSEDEMCISSQQPSP
KIPVIPVTNLWSGGFSAASGKPVILSSVALEKAQTLFSDISLNMDKVAESAPFKKDKKHQ
TEPENICSGFTTAGGANDQMSQEKFDDLVLAKAVQEEEALSADGVLESNNVMWESAGSKK
EDETPYADQRFRTNTPVEAVKGCFRDTDKQEKHKENLLPQASCGFKTASGKKVEVSSEAL
KKAENLLGDCVGVMDTVNAALPESKAIDLPVRNDGFRSASGKPVALSSEALQKAKSLFSD
IGFGAEDPDASQMIKSGKNQGGSNNTEKMSCGFTTARGEKVDVLQKNLQKAKVLFKELDD
QVLSKAAQEEDAFFAGHDMDINKEMLENDLKGKVHMQRSRKACLAKCYTDDEKRVSISIP
ECSRDANKQVEQRENILLQASCGFQTASGKRVDVSSEARKKAETLFSEFEEIQDKTNAMS
SQSKPSALPLRNCGFHSASGKPMAPSTEAVQKAKSLFGDITFSTEDSDFSQTVKAYGKQD
SRSKTEKICCGFTTAKGEKVDVLQKNLQRAKFLFKEVDDLDLTKAMQDADHFFNQEEGWS
IDSNSEKSSEQTNTAPVNESGSIKGNMSKLRTNTGSICEEPGNGSIKAKQNDSGFQTASG
KTVAVSAEALSRAKFLLSENKADEESTCVFPASGKRFSHEGLQKAKTSTGGKSLPSGADS
LSDDHIEEKSHFSICNLNTKSSNQISDIMQKNKSSDPKFQSLNLAGCTETQHKFLAQEAL
DCTKALLEDEVLVGQSLLTTSENLQLLDYQQLSEKSAEEDKGRKRRSAEDLTAQPPSKRR
LLEEFDRTANNPRGSGLHPVKSGPNGIMDRGVFRYGVFLHPNITKPNRDAKSFVDTRLQN
TIQMPHSEQGDGRSAACRMPTFVPPFFKNAKRDALNKPEARDRKKVPAFVPPFKKQRVVQ
QESSPTQQEDNKQHHSLCLETNSKTDAPLTKTTQSCEEVVTLVNTSNTKTINQSVLKVGS
VSSTEMLHVDDKLSGSQDRTENIGLARDMQDMRIRKKKRQTIRPLPGSLFLTKTSGVARI
PLKAAVNGNIPGRYSSQELYECGVHKHVPEITSQNAESFRFNLLQFVKQETLAEGGGVQL
ADGGWLIPSDDWTAGKEEFYRALCDTCGVDPKLVSEQWVYNHYRWIVWKQASMEKSFPGT
MGSLCLTPEQVLLQLKYRYDVEVDHSRRPALRKIMERDDTPAKTLVLCICEIISKCQLLH
AQSCSDTKMSQSAETKVETPVAVVRLTDGWYAIKAQLDEPLTAMLHKGRLAVGGKLIIHG
AQLMGSQDGCSPLEAPDTLMLKICANSTRRARWDAKMGFHTDPRPFLLPISSLYSNGGAV
GCVDIFILRSYPMQWMERKSDGGVVFRSVRAEEKEARRFNSHKQKAVELLFAKVQAEFEK
EEEGRIKRQRRRQTVGKQDIGNLQEGEDLYEAVGDDPAYLEAHLSEQQLETLQAYRRSLM
EKKQAELQDRYRRALDAEDNEMSCPKRDVTPVWRLCVADSMTQSSCVYQLNLWRPSSDLQ
SLLKEGRRFKVYNLVASDGKKRSSVETVQLTGTKKTQFQELQVSQEWVSSHFRQRISTDF
VDLQNEEFKPLCGEVDLTGLVISVVDQQGSSPAFYLVDGKKNFVKVRCFSSLSQAGLEDI
VKPRVLLALSNLQLRGQSIHPTPVVYAGDLTVFSTNPKEIHLQESLDQLKNVVQGQDHFF
LTAEEKLAHLIKSDGSCSSSLQPQTPVAARRQDSKTNVAFLKPIKSLGSFTPVSSNLPAA
TSSTEKDPKTLKRKRALDYLSRIPSPPPISPLGSVVSPCVNKTFNPPRRSGPPSTLKPVQ
PAAPKATDSVVEDEWVNDEELAMIDTQALHVGNLF
NT seq
9108 nt
NT seq
+upstream
nt +downstream
nt
atggattcatgcataaaaaacatgtacgatgcatttaagggtgaaatctggaaagagctg
ggaccgttggacccaaactggtttgagttactgacagcccaagcttctttgaaagaagga
agtgttgccgataatgatgagttgtgcgccaaccaagagggacatttcaaagctcctctg
gagaagacggcaacagaaagccagctgttttcaacccctaaagttttcagacacagtcga
attgtgtcaccagacactgaggatgacccgtcgttcacagctgcacaggaaaaagaaacg
ttaccgtggatgccaacacaaagtccctgtttgtttcaggtgccaaaacactgtgtctct
aatttaaaatgtgaaggtgttcagcctcagagtgaggagagttttgatcttctggattcc
ccaaagaaatcccctgccacctatgccaaccacatttctgaaagtctcggcgcacagatc
aatcctgacatttcttggaccagttctttgaatacaccaccggctttgccatctactcta
attttatctaaaactgatgagagtccctgtccagtgagtgttactgcagacagaaaagtt
gtttttgtacggaagcttttcccttcactttcgaattcctcccttaagacttcaagaact
tgccaaggtccagttttccctgtgactgaaacctgctctgagtctccgttgaaccagagt
gaaagtcatcaacaacagaaagttccagatgctctggaaggagaagtctgtatcgcagat
gcacctaaaactttctttgctaatagtagttctgctctgagaaaagtgaaacccgacaga
gttaaacgtaagcaaataattcagacaaatgtagacgtctgcagccacgaagacgcctca
aaatcagacagtgctgcatccaatgaagaggcaactgctgatctggattctgggggtttg
ccttcaaccccactggtgaaaactggagatacggcaatcagccagtggtctcctctaagt
ctatctgaaatttcatcttctgctgtgggaagcaatatgacactgccaggggacactgac
tctgtgcaaccaaccaggccaacatcgaaaattactgactctggatttactcaaaaaaag
agaaaatttgtttacactattacaaccacaaaatcgcaagcttgtggccaagactttgag
ctccagacagcagatctgtcactaaagatttcagagtctgaacaagaaaacggcaagtca
tttgtgaacatcccagataaagaagagtgtcagaggactaaaaaccaaagaaatattgta
gaggaaaccataaattgctctcttgggacaaaactccaggatatcgacatgtcacaactt
tgtcgagattttgcactggacttcagccaaatgacagacttaaaaactgcagagaacacg
caaaggaacttctctcctgcagcgtgtctgtctgttatgaaacaagcaaaacagaacgga
aagccagctaactttcccaatgattacagttgtatcagtaaaaacagacgcatccctacc
agtaatcaaccatgctcgatcagtgaagtcactatgattgacagcggattccaatcaggt
gtagcagacgtcacccatatgacttcttcgtcatttggtcttccgctcttagagaatgtt
agccaaaaccgaccaacgctgagcttcaaaaccggtatgcataattttccctcagctaat
ggaagtggaaagtcaaaatttgatgttgaagtgcctgtgcagaggtctggcacaggtcag
gctccggaccatggaaaggaaattgagttgcacatggcgagcatatcaacagaggaacta
tgggacaaagaagaaactgttggtcaaaataaatgcagccagccacaaaaaactcctctt
tctcttctgcctgctgaagcatcaggattcaaaaccgcctcaaataaaggcatccacatt
tctcttgcaaacctggagaaagcaaagctttttcttgaagcgactgaagataaaaagtct
tctctcgataacagcacaaaatcctatcatggcattatttataaaactaattcgattcgt
gaaacaacaacagatacatcatctaacgcaaacccgcccgcctgtgccggaaagtcattt
ggaaatgtcagttctcaattaacagcctcagaaaaagccgatgtgacagaactttgcaca
ctcttggaagaggcagacagccaatttgagttcacacagttcagatctggaaaaaaacta
ccaaatcatcaagataatcacaatccgccacacaaagaagacaaggatcttgaccctgct
cttcttgcagatatagactttgacgacagctttagttccgaaggtggaaaacagtccaca
gtcatgatgaatgacaaagtggcctcagttttagaaaacaggacacatggagaaaaagca
aaagccataaatcagtgtacaggaatgtcagatttgctgaaaagggaaactccgctcatt
cttcctggggctgaggatcctgaagctaaatgtctggagaacaacaaggctttgatccat
agtgaagcatttaggacagcaggtggaaatgttttgcatgtttctacaaagtgtctgaac
aaagccaaggctttgtttggagatctggagagaaacttgacagaccagaaaccttctaac
cagaacggggaaaatgctgccataacagaacagaaatgtaaccgggattctgacacgttc
agaatcccggaaagaaagaaggaaaactgggatgtcggaaccaaaattgagaattgcttt
tccaaattagaaggggttgtctgttcaaataacaacgttggaaacaggaatgacaccaaa
agtgggaaaaacaatggaattgacacaataatctgtgaaaatggattcagaaaggccagt
gggaaaggaatctccatttcagctaactacatgcaagaagcagatgtatttttcaaagac
tgccatgtaatggagcacaaagaaggtaagaaaagcttttcaaacttcaaaagccctcag
gtcagcatttctaagaagagtgtcactggatgcactaaacttgaaaatgtaaatacagca
gtggtttcacatcacacaaaaggactacgtctgaatgaagtggaaagaaataccaagttt
acagcagctttgaaaaatgaagacggaaaatcttttccgacttcaaagccgttcgctatg
cttcacccatcaaagagcacggatttgtctgcttttgaagagctgtgcacaggtgatggg
ttttgtacagctgctgggaagaacattagtgtgtcgtctgctgcgatgaagaaggctgaa
tttcttttgaatcagattcacgcacccgaggagataaacaaagaaactaatgaaaaagaa
aaggcttcaaaaacaaaatgccttggtgataagatttcgaacgtagatactggtggtttc
caagctgttgatggaaaaaaatttgcaatttcatcagcaccgttaaagaaagcaactctg
ctaagagaatctgaaaaatcagaggatgaaatgtgtatttcctctcagcaacccagtccc
aagataccagttatcccagttactaatctctggagtggcggtttttctgcagccagtggt
aagcctgttatcttgtcatctgtggctttggagaaggctcagacactgttcagtgacatc
agtttgaacatggataaggtggccgaatctgctccatttaaaaaggataagaaacatcaa
acagaacctgaaaatatatgttctggtttcacaactgcaggaggcgcaaacgaccaaatg
tcacaggaaaaatttgatgatttggttttagccaaagcagtgcaagaggaagaggctctc
tccgccgacggtgttctggaaagcaacaatgtaatgtgggagagtgcggggagcaagaag
gaagatgaaacgccttatgcagatcaaaggtttagaacaaacacacctgtagaggctgtg
aaaggatgcttcagggatacagataaacaagagaaacacaaagaaaaccttttaccacaa
gcaagctgtggatttaagacagccagtgggaaaaaagttgaagtttcatctgaagctctg
aagaaagcagaaaacttgttaggtgactgtgtaggagtcatggatacagtaaatgcagca
ctgccagaatccaaggctattgatcttccagtcagaaatgatggatttcgatctgccagc
ggtaaacctgtagcactttcatcagaggctcttcaaaaggcaaaatctctcttcagtgac
atcggtttcggagcagaggacccagatgcttcacagatgatcaaaagtggcaagaaccaa
ggcggtagcaacaatacagagaaaatgtcttgtggtttcacaactgcaagaggggaaaaa
gttgatgtgttacagaaaaatcttcagaaggcaaaagtacttttcaaagaacttgacgat
caggttttaagcaaagcggcacaggaggaagatgctttctttgcaggccatgatatggac
attaataaggaaatgttggaaaatgacttaaaaggaaaagtacatatgcagagaagcaga
aaggcatgtcttgcaaaatgttacacggatgacgagaagagggtaagcatttctatccct
gagtgctccagggatgcaaacaaacaagtggaacaaagagaaaacattttactgcaagca
agctgtggatttcaaacagccagtgggaaaagagtcgatgtttcatctgaagcccgaaag
aaagcagaaaccttgtttagtgagtttgaagaaattcaggataaaacaaatgcaatgtca
tcacaatccaagccttctgctcttccactcagaaactgtgggtttcattctgccagcggt
aaaccaatggcaccttccactgaggctgttcaaaaggcaaaatccctctttggtgacatc
actttcagtacggaggactcagatttttcgcagacagtaaaagcttatgggaaacaagac
agtcgaagcaaaactgagaaaatatgttgtggttttacaaccgcaaagggagaaaaagtt
gatgtgttgcagaaaaatcttcaaagggcaaaattcctctttaaagaagttgatgactta
gatttaacaaaagcaatgcaagatgcagaccatttttttaaccaagaggaaggttggtct
atcgacagtaacagtgaaaaatcatcagaacaaactaatacggcacccgttaatgaaagt
ggcagcataaagggaaacatgtccaaactcagaacaaataccggcagtatttgtgaagag
cctggaaacggttccatcaaagcaaaacagaatgacagtggatttcagacggcaagtggg
aaaacagttgccgtttcagctgaagctctgtcgagagcaaaatttctgctgagtgaaaac
aaagcagatgaggagagcacttgtgtctttcctgcaagtggtaaacgattttcacatgag
ggcttacagaaagcaaagactagcactggagggaagtcattaccttcaggagcagacagc
ctaagtgatgaccacatagaagaaaagtcacacttctcaatttgcaatttaaatactaaa
agcagcaaccagatatctgacattatgcaaaaaaataaatcttcagacccaaaatttcag
tcgctaaatctcgctggctgtacagaaacacagcacaagtttcttgcccaggaagcttta
gattgcacaaaagccttactagaagatgaagttctagttggtcaaagtctgttgacgact
tcagaaaatttgcagttgctagattaccaacaattaagcgaaaaatcagctgaagaggat
aaagggaggaaaaggagaagtgcagaagatctcactgctcagccaccttctaaaagaagg
ttactggaagaatttgacagaaccgctaataatccacgaggttcaggactccacccagtg
aaaagtggcccaaatgggataatggacaggggtgttttcaggtatggcgtctttcttcat
ccaaacattacaaagccaaacagggatgcaaaaagctttgtggacacaagattacaaaat
acaatacaaatgcctcattctgaacaaggagatggtcgatctgcagcctgcaggatgccg
acatttgtcccaccgtttttcaaaaatgcaaagagagatgcactcaataaaccagaggcc
agagatcgcaaaaaagtgcctgcgtttgttccaccgttcaaaaaacaaagggttgtccag
caagaaagctcccctacacaacaggaggacaataagcagcatcactctttatgtttggag
accaacagcaaaacagatgcaccacttactaaaacaacccaaagctgtgaagaagttgtc
actttggtcaacacttcaaacactaagacgattaatcaaagtgttctaaaggtgggatct
gtcagctctactgaaatgctacatgtggatgacaagctttccggaagccaagacaggact
gagaacattggactggcccgggacatgcaggacatgaggattaggaaaaagaagcggcaa
accattcgaccgctgcctgggagcttatttctgacaaaaacctcaggagtggcgagaatc
ccattaaaagctgcggtcaatggaaatatcccaggaagatactcgtcccaagagctgtat
gagtgtggagtccataagcatgttccagagatcaccagtcagaacgctgaatcgtttcgc
ttcaatttgctgcaatttgtcaaacaagaaacgttagccgaaggaggtggtgttcaactc
gctgacggaggctggttgatccccagtgatgactggacagcaggaaaagaagaattctat
agagcattatgtgacacttgtggtgtggatcccaaactggtcagtgagcagtgggtgtac
aatcactacaggtggattgtgtggaagcaggcctccatggagaaatcatttccaggaaca
atgggcagcctttgcctgaccccggagcaggttctcctccagcttaagtacagatatgac
gtagaggtggaccacagccgcagaccagctttgaggaagatcatggaaagagatgatacg
ccggccaaaactcttgttctctgtatctgtgagatcatttctaaatgtcagctcctacat
gcacagagctgcagcgacaccaagatgtcacaaagtgctgaaaccaaggtggaaactcca
gttgcggtcgtgcgacttacagatggctggtatgccatcaaagctcagctggatgaaccg
ttgactgcaatgcttcacaaaggtcggcttgctgttggtggcaaattgataatccatgga
gcgcaactgatgggatcacaagatggttgctcccctttggaggcaccggataccttaatg
ttgaagatttgtgccaatagcactaggcgtgcacggtgggatgctaagatgggatttcac
acagacccacgaccatttctgcttccaatctccagcctgtatagtaatggaggggcagta
gggtgtgttgacatcttcatactgagaagctatcccatgcagtggatggagaggaaatcg
gacggaggtgttgtgtttaggtccgttcgggcagaagagaaggaggcgagacgattcaac
agccacaaacagaaagcagtagagttgctgtttgccaaggttcaagctgaatttgaaaaa
gaagaagaagggaggatcaaacgtcaacgcagaaggcaaacggttggcaagcaggatatt
gggaacttgcaggaaggagaagacttgtacgaagcagttggagatgaccctgcttacctg
gaggctcatttaagtgaacaacagctggagactcttcaggcctacaggcgctcactgatg
gagaagaagcaggctgagctacaggacagatatcggcgtgctctggacgcagaggacaat
gaaatgagctgtccgaaaagagacgtgacacctgtatggagactttgcgtcgctgactca
atgactcagtccagctgcgtttatcagttaaacctttggcggccttcttcagacctccag
tctttgctgaaggaaggtcgtcgattcaaagtgtataaccttgttgcctctgatggaaag
aagcgtagcagcgttgaaactgttcagctgaccgggacaaagaagacacagttccaggaa
cttcaggtgtcccaagaatgggtgtcctcgcattttcggcaaagaatctccacagacttt
gtagatcttcagaatgaggaattcaagcctctgtgtggagaagttgatctcacaggttta
gtcatcagtgttgtagatcagcagggttcctctcctgcattttatttggttgatgggaaa
aagaattttgtgaaagtgcgctgcttcagcagcttgtctcaggccggccttgaagacata
gtgaaaccacgtgtccttttggcactgagcaacctgcagctcagaggccagtctatacac
cccactccggttgtgtatgctggggatctgactgtcttctctacaaaccccaaggagatt
catctacaggaatccctcgaccaactcaaaaacgtggtacagggtcaggaccacttcttt
ttgactgctgaggaaaagcttgcccatttaatcaagtctgatgggtcctgctcttcatct
ttgcaacctcaaacgccagtcgctgcaagaagacaagactcgaagacaaatgtggccttt
ctgaaaccaatcaaaagcctcggatcatttacacctgtcagcagtaaccttcctgctgca
acatcttcaacagaaaaagaccccaaaaccttgaaaagaaaaagagctttggattatctt
tctcgcatcccgtctccaccacccatctctcctctgggctcagtggtgtctccttgtgta
aataaaacattcaaccctcctcgaaggtctgggcctcctagcactttaaagcctgtacag
cctgctgcaccaaaagctactgattctgtggtggaggatgaatgggtgaacgatgaggaa
ctggctatgattgatactcaggcgttgcatgttggcaatttattttag
DBGET
integrated database retrieval system
