KEGG   Poecilia mexicana (shortfin molly): 106927347
Entry
106927347         CDS       T08022                                 
Symbol
plcb4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
pmei  Poecilia mexicana (shortfin molly)
Pathway
pmei00562  Inositol phosphate metabolism
pmei01100  Metabolic pathways
pmei04020  Calcium signaling pathway
pmei04070  Phosphatidylinositol signaling system
pmei04081  Hormone signaling
pmei04082  Neuroactive ligand signaling
pmei04261  Adrenergic signaling in cardiomyocytes
pmei04270  Vascular smooth muscle contraction
pmei04310  Wnt signaling pathway
pmei04371  Apelin signaling pathway
pmei04540  Gap junction
pmei04621  NOD-like receptor signaling pathway
pmei04912  GnRH signaling pathway
pmei04916  Melanogenesis
Module
pmei_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:pmei00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    106927347 (plcb4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    106927347 (plcb4)
   04371 Apelin signaling pathway
    106927347 (plcb4)
   04020 Calcium signaling pathway
    106927347 (plcb4)
   04070 Phosphatidylinositol signaling system
    106927347 (plcb4)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    106927347 (plcb4)
   04081 Hormone signaling
    106927347 (plcb4)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    106927347 (plcb4)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    106927347 (plcb4)
  09152 Endocrine system
   04912 GnRH signaling pathway
    106927347 (plcb4)
   04916 Melanogenesis
    106927347 (plcb4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    106927347 (plcb4)
   04270 Vascular smooth muscle contraction
    106927347 (plcb4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:pmei04131]
    106927347 (plcb4)
Enzymes [BR:pmei01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     106927347 (plcb4)
Membrane trafficking [BR:pmei04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    106927347 (plcb4)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    106927347 (plcb4)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like PLC-beta_C C2 PKK EF-hand_7 EF-hand_6
Other DBs
NCBI-GeneID: 106927347
NCBI-ProteinID: XP_014858346
Ensembl: ENSPMEG00000012578
UniProt: A0A3B3X635
LinkDB
Position
Unknown
AA seq 1238 aa
MTKSYEFNWQKHLPEFMQEGASFDRFDEDPYLFEPNCQMKVDEYGFFITWKSEGKEGQVL
ECSLINSIRVGAVPKDPKILSSFEAIGKTEADLEGCIICICSGTDLVNLSFMFMVAESPD
TARKWIEGLRSVIHNFKANNVCPMTCLKKHWMRMCFLTNVNGKIPVRGITRTFASGKTEK
GIFQALKDLGLPSGKNDEIEPSDFTFDIFYALTQKICPRTDIEELFKKINGNKTDYLTVD
QLVSFLNENQRDPRLNEILFPFYDPKRAMQIIEKYERDEELKKKGRMSSDGFCRYLMSDE
NAPVFLDRLELYQDMDQPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLSGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSDYPVILSFENHCSKLQQYKM
AKYCEELFGDLLLRQPLENYPMDPGHPLPSPNDLKRKILIKNKRLKPEVEQRQLEALKKH
MEAGETNTPAIIMGEENEDDAENGEKEAEDKDLNSEAPSILSEVTSDKETNSVSQSNAIS
SGKEEERSNSIKKVPDDEVTEISEATDATDISEASDQDNNKKGGDVAEDSEEALIAQYKY
ESATTNIHPYLSAMVNYAQPVKFQGFDVAEERNIHHNMSSFNESVGLGYLKTNAIEFVNY
NKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVSLNFQTPDLAMQLNQGKFEYNGCCGYL
LKPDFMRRSDRTFDPFSETPVDGVIAATCSVQVFSGQFLSDKKIGTYVEVDMYGLPTDTI
RKEFRTRMVMNNGLNPAYNEEPFVFRKVILPDLAVLRIAVYDDNNKLIGQRILPLDGLQA
GYRHISLRNEGNNPLSLPTVFCQIILKTYVPDGFGAIVDALSDPKKFLTIAEKRADQMKA
LGIDTNDIADVPNGSSKNDKKGKGKGDTGKASVTQQASSDMAQTSNSVQNNTNENKKDAA
LVPNVSIDDLKQMKSYLKLIKKQQKELNALKKKHSKDQNAMQKAHCTQVDKLVSLHEKEK
TNLEKLLEKAIKKRGENNCQELKKETEDKIQTLTTDHKAKVKDITAQHTKEWSELISSHS
SEEREMKDSHVTQQCEHLKKLLSSVQEQQTLQLKLIHERQSKEMRANQAKMSMENSKAIS
QDKSIKNKAERERRVRELNCSNTKKFLDERKRLAMKHQKEMEQLEKNQKEQLDKLEKHNE
QLLKSHHANKQVQGQGHPADGEVGGGDGPQTCHGGLSD
NT seq 3717 nt   +upstreamnt  +downstreamnt
atgacaaagtcctatgagttcaactggcagaagcacctgcctgagttcatgcaagaaggt
gcctccttcgacaggtttgatgaggacccatacctctttgagcccaactgtcagatgaag
gtggatgaatatggcttctttatcacatggaagagtgagggaaaggagggccaggttctc
gagtgttctcttatcaacagtatccgtgttggtgccgtccctaaggacccaaagatcctg
tcctcattcgaggccataggaaagactgaggccgacctggagggatgcatcatctgcatc
tgcagcggcactgacctggtcaacctgagcttcatgttcatggtggcagagagccccgac
acagccaggaaatggattgagggtttgaggtcggtgatccacaactttaaggccaacaac
gtgtgtccaatgacatgcctcaagaaacattggatgaggatgtgtttcctgaccaatgtc
aacgggaagatccctgttagaggtatcacaagaacctttgcatcagggaagacagagaaa
gggatctttcaggctctgaaggatctaggtcttcccagtggaaagaatgacgagattgaa
ccctcagacttcacctttgacattttctacgcgctgacacagaagatctgccctcgcaca
gatatagaggagctcttcaagaaaatcaatgggaacaaaacagattatttaactgtagac
cagttagtcagctttctgaatgaaaaccaacgtgacccgaggttaaatgagattctgttt
ccattttacgaccccaaaagagccatgcaaatcatcgagaaatatgaaagggacgaagag
ctgaagaaaaaaggccgcatgtcgagtgacgggttctgtcggtacctaatgtcagacgaa
aatgctccggtgttcctggacagactagagctgtaccaagacatggatcagcctttggct
cattactttatcagctcctcccacaatacatacctgacaggaagacagtttggagggaag
tcatcagtggagatgtaccgccaggtcctgctgtccggatgcagatgtgtggagctggac
tgctgggatggcaaaggggaggaccaggaacccatcattactcatggcaaggccatgtgc
acagacatcctgttcaaggatgtgatccaagcaatcaaggagacggcgtttgtcacatct
gattatcctgttattttatcatttgaaaatcattgcagtaaactacagcagtataagatg
gccaagtactgtgaggagctctttggtgacctccttctcagacagcctctggagaactac
ccaatggatcctgggcatcctttaccttcaccaaacgacctgaagagaaaaatcctaata
aagaataagcgattaaaacctgaagtggagcagaggcaacttgaagctttaaagaagcac
atggaggccggcgagaccaacactcctgctattattatgggagaggagaatgaggacgat
gcagagaacggggaaaaagaagctgaagataaagacttgaattcagaggctcccagcatt
ctgtcagaagtcaccagtgacaaagagacgaacagtgtttcccagagcaacgccatcagc
tctggaaaagaggaagagcgcagcaacagcatcaaaaaggtacctgatgatgaggtcacg
gagatttctgaagcaacagacgccacagatatttctgaggcatctgatcaagacaacaac
aagaagggcggagacgtggcggaggattctgaggaggctctgatagcgcaatataaatat
gaatcagccaccacaaatatccacccgtatctctcagccatggtcaactatgcacagccg
gtgaagttccagggttttgatgttgcagaagagaggaatatccaccacaacatgtcatcc
ttcaacgagtcagtgggcctgggctatctgaagaccaacgccatcgagtttgtcaactac
aacaagcgtcagatgagccgtatctaccccaaaggaggcagggtggactccagtaattat
atgcctcagatcttctggaacgcaggctgccagatggtctccctcaacttccagacccca
gatctggccatgcagctgaaccaaggaaagtttgagtacaacggctgttgtgggtacctg
ctgaagccagatttcatgcgtcggtcagacaggacgtttgacccgttctctgagacgccg
gtggatggcgtcattgcagcaacctgcagcgtccaggtgttctcaggacagtttctgtct
gacaaaaaaattggcacgtacgttgaagttgatatgtacggcttgcctacggatacaatc
cggaaagagttccgcacacgcatggtgatgaacaatggactgaatccagcctacaacgaa
gagccctttgttttcagaaaggtaatcctaccagatctggcggtgctgcgcatcgcggtg
tacgatgacaacaacaagctgattggccagcgcatcctgcctctagacgggctgcaggct
ggctaccgtcacatctccctgaggaacgaaggcaacaaccctctgtcgttgccgaccgtc
ttctgccaaatcatcctcaagacgtacgtgcccgatggcttcggagcaattgtggatgct
ctatcagatccaaagaagtttttgaccatagcggagaagagagccgaccagatgaaggcc
ctggggattgacacgaatgacatagcagatgttcccaatggaagctcaaagaacgacaag
aagggaaagggaaaaggagacacagggaaagccagtgtgacacaacaagccagctcagat
atggcccagacctccaactctgtccagaacaacacaaacgagaacaagaaggatgctgcg
cttgtgcctaatgtgagcattgatgacttaaagcaaatgaagagctacctaaagctgatt
aaaaagcagcagaaggagctcaacgctttaaagaagaaacactcaaaggatcaaaatgca
atgcagaaagcccattgcactcaggtggataagctggtgtccctccatgaaaaggaaaag
actaatctggagaaactgttggagaaagccatcaagaaacgaggggagaacaactgtcaa
gagctgaagaaggagacagaagataagatccaaactctcaccacagatcataaagcaaag
gtgaaagacatcacagcacaacacaccaaggagtggtcggagctcatcagtagtcacagc
agcgaagagcgcgagatgaaggacagtcatgttacccagcagtgtgagcacctcaagaaa
ctcctttctagtgtccaggagcagcagaccctgcagctcaaactcattcatgaaaggcaa
agcaaagagatgcgtgccaaccaggctaagatgtccatggagaacagtaaagcaatcagc
caagacaaaagtatcaaaaacaaggcagagcgagagaggagagtgcgggagttaaactgc
agcaacaccaagaagtttttggatgagaggaagaggttggctatgaaacatcagaaggag
atggagcagctggagaaaaatcagaaggagcagttggataaactggagaagcacaacgag
cagcttttgaaatcacaccatgcaaacaaacaggttcaaggccaaggacatccagcagat
ggtgaagttggaggaggagatggaccgcagacctgccacggtggtctgagcgactga

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