Poecilia mexicana (shortfin molly): 106930732 Help Entry 106930732         CDS       T08022                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism pmei  Poecilia mexicana (shortfin molly) Pathway pmei04020   Calcium signaling pathway pmei04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:pmei00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     106930732 (ryr3)    04020 Calcium signaling pathway     106930732 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:pmei04040]     106930732 (ryr3) Ion channels [BR:pmei04040]  Voltage-gated cation channels   Ryanodine receptor    106930732 (ryr3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_8 Motif Other DBs NCBI-GeneID:  106930732 NCBI-ProteinID:  XP_014863956 LinkDB All DBs Position Unknown AA seq 4858 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQSVATIQKEHRKFCLAAEGLGNRLCYLEPTSEAKYVPP DMCICNFVLEQSLSVRALQEMLANTGASSEGKADHEKWRLIKKAGQGGGHRTLLYGHAIL LRHSFSDMYLTCLKTSRSLTDKLSFDVGLQEDSVGEACWWTIHPASKQRSEGEKVRIGDD LILVSVSTERYLHLSNCNGNIQVDASFMQTLWNVQPTCSSGSMAVGYLIGGHVMRLCHGH DESLTIPGADKSEEEQRIVNYEAGKGASRARSLWRLEPLRISWSGSHIRWGQSFRLRHLS TGRYLALTEDRGLVLEDREKCHTKATAFCFKPSKEKGDSGMKRDIDGMGVPEIKYGDSVC FVMHVATGLWLSYLAPDAKSSRLGPLKRRACLHSEGHMDDGLILQRCQHEESRAARIIRN TTFLFRNFIKALDSAAAGETNAVAGYVEEVLQTLNDLIEYFKQPDVDLEHEEKQARLRSL IKQQDLFKEEGMLALLSKCIDRMNLYDSAAHFGEMAGEEAGAAWKDILNLLYELLAALIR GNRTNCTQFSRNLDWLVSKLERMESSSGILEVLHCILVESPEALNIIQKGHIKSIISLLY KHGRNHKILDVLCSLCVCNGVAVRTNQNLICDNLLPKRDLLLQTRLVNDVQSMRPNIFLG IAEGSAQYKKWYYELVIDQVDHFVTGEPTHLRVGWANTKGYAPYPGGGEGWGGNGVGDDL YSYSFDGLHLWSGRIPRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDF NTDGFFFPVVSFSAGVKARFLLGGRHGDFKFLPPAGYSPCYEALLPKEKMHVEPVKEYKR DHDGVRDLLGTTQFLSQASFIPTPVDTSQIVLPPHLENIRDKLAENIHELWGMNKIELGW TYGKVRDDNKRQHPCLVDFSKLPETEKNYNVQMSSETLKTLLALGCHVAQVNVHAEEDLK KIKLPKDYMMSNGYKPAPLELSDVKLTPGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQ DVKSRRNPRLVPYALLDERTKKSNRDSLREAIRTMVGYGYDIDPPDQEVVHAIDNQSIET IRFFRVEQTYAVKTGKWYFEFEVLSGGDMRVGWARPGCRPDVELGTDDQAYVFDGYRGRR MHAGSRYFGHPWKKGDVVGCMINMEDKSMIFTLNGELLITSKGSELGFADFETEDGFIPV CSLGMSQIGHMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREITMWFSKRLPTFFNVPQD HMHIEVTRIDGTVDSPPCLKVTHKTFGTQNSNSDMVYCRLSMPVEFYSADRLLDESLKLS QPPKEDGSIDYGSITTYYHSVRVFAGQDPGSVWVGWVTPDYHYYSKNFSLSKTQTVTVTL GDERGRVHESIQRSNCYMVCAADALGPSSSSRSNTDLEIGCLVDLATGLVSFTANGKELP TAYQVEPNTKLFPAVFCCPTSSNLFQFEFVKIKDAMPLSSAMFRSEQRNPVPQCPPRLDV QTIVAVLWSRMPNTFLNVETARVSERHGWVVQCLEPLQMMAVHIPEENRCLDIMELSEHE DLRKFHSHTLKLYCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGMLREGFYDVLIS IHLETAKEARLMMNNEFIIPVTDETRSIKLFPDESKRHSLPGVGLSTSLKPRVNFSPVGI ISTKRHQLLYSPQIPLGILKEKAISMLTEAVQGGGSHIRDPVGGSLEYQFVPILKLIGTL LIMGVLTSDEVRLILLLIEPNVFGEAKEGEEGSEVVVAGEKEEVSKNEEKAVEAGEEETK ESKPAAKGLLEKSLPESVKRQMCELLHYFCDCELQHRIEAIVSFSDRFVSKLQYNQKFRY NELMQAFNMSAAVTAKKTKEFRSPPHEQINILLNFSAGEDCPCPEEIQDELTSFHEELRL HCGIPVEEEEEEQDTSIKGRLLALLYKIKGPPQKTEEEPAETEQAAPTNLKELISQTITS WAQESHIQDPELVRVMFSLLRRQYDGIGELLRAMKKSYTISAASVQDGINLLASLGQIRS LLSVRMGKEEEKLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGDKSQEIA FPKMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASEAMRGSTPLDVAASSVM DNNGLALALEEPDLEKVVMYLAGCGLQSCAILVAKGYPDLGWNPIEGERYLSFLRFVVFC NGESVEENANVVVKLLIRRPECFGPALRGEGGQGLLAAMKEAIKISEDPALDLPKSPAGA TAGSGEEEGEVIHMGNAIMSFYSALIDLLGRCAPEMHLINAGKGEALRIRAILRSLVPTS DLVGIISIPLKMPVINKDGSVTEPDMSACFCPDHKAPMVLFLDRVYGIEDQSFLLQMLEV GFLPDLKASASLDTEVLSTTETALAMNRYIGSALLPLLTRCAALFGNTEHYAHLVDSTLE TIYRLSKGRSLTKAQRDAIEECLLAICKHLRPSMMQQLLRRLVFDVPLLTEYCKMPLRLL TNHYEQNWKYYCLPSGMGGFGMASEEELLLTKKLFWGIFDSLSQKKYDSELFKMAKSCLC AIAGALPPDFVDTSLGATVEKQESVDAQGNFEPKPINTANISLPEKLDYIANKYAEHSHD KWASEKMSAGWKHGDSLDEQAKAHPLLKPYKSLSEKERETYRWPVKESLKSMLAMNWNIE RTKEGEAMFQQRESEKQRKLSETQSNGFSPAPMDLHNVTLSRELQSMVEVVAENYHNIWA KKKKSELLSKGGGLAHPLLVPYDTLTAKEKYRDKEKAQELFKFLQISGYAITRGLKDMEQ DSSSMEKRFAYKFLKRLLKNIDSAQEFIAHLEAMATSGKTDKSPHDQEIKFFAKVLLPLI DQTFKNHCLYFLSTPSKNLSSCGCASNKEKEMLTSLFCKMAALVRHRISLFGSDSAIMVS CLHILSHSLDTRTVMKSGAELVKVGFKAFFENAAEDLEKLVEMLKLGKFMQSRAQMKSVT QSINYVTVALLPILTALFEHIRTYEFDVDLLVDDVQLSCYRILMCFYSLGTGKNVFVERH LPAIGESLAILVGAMPVAFLEPHLNAHNPLSVFNTKTARERAILSMPDTVEEMCPEMPRL DKLLKDVNDVSECGARYSDMPQVIEVVLPMLCNYLSYWWEKGPENSPPDTDCCTMVTSEH LSIILGNILKILNNNLGIDDAPWMKRIAVYSQPIICKAGADLLRTHFLPTMEKLKKKTVK VVSEEELLKADGKGDNQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSRWLKEPDADS TELFRMVAEIFILWCKSNNFKREEQNFVIQNEINNLGFLTGEGKSKMSKSGGDQERKHKR RRGEYYSIQTSLIVAALKKLLPIGLNMCTPGDQELISLAKIRYSLKDTDDEVKEHLRQNL HLQEKSDDPAVHWQLNLYKDVVVKSEEPSDSEHTVDRIQSISAAVFNLEQVEQPLRNKKC IVQKLLSKQRKRAVVACFRMAPLYNLPRYKNNNYFLNGYREVWLERAFKASSFDRLFSLL TKTPMKIVEEEEEEVAEIKPDPLHQLILHFSHNALTERSHLEVDPLYIAYADMMAKSCAE DEEEEEEEGREKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISASKGRLGPMVTCTLK LGISILNGGNVQVQQKMLGYLTDKRDAGFFKSLSGLMQSCSVLDLNAFERQNKAEGLGMV TEEGSINTQRGSKVLQNDEFTKDLFRFLQLLCEGHNGDFQNFLRTQTGNTTTVNIIISTV DYLLRLQESISDFYWYYSGKDVIDETGKHNFSKALSVAKQIFNSLTEYIQGPCIGNQQSL AHSRLWDAVVGFLHVFANMQMKLSQDASQIELLKELMDLQKDMVVMLLSLLEGNVVNGTI GKQMVDTLVESSSNVEMILKFFDMFLKLKDLTTSDNFKEYDPECKGIISKKEFQKSMESQ KQYNQSEIEFLLSCAEADENDMFNYKEFVERFHEPAKDIGFNVAVLLTNLSEHMPHDARL ATFLDLAESVLSYFEPYLGRIEILGSAKRIERVYFEISESSREQWEKPQVKESKRQFIFD VVNEGGESEKMEMFVNFCEDTIFEMQLASQISEPDAVEQPEEEEEEEVHNILEELSGGDA AALESTSAFTTACRSVKKSLSEIRQIFTIKTARKQFKKIKKLSIKELITGFFSFFWMIFI GFFKGIISLVFGFFHVIWSSMFGGGLVEGAKNIKVTDILGNMPDPTQFGIHGDVGEGDKV EAMESSGSLDKAMAPAGDATEVDVMLEMLTPKKEGGKHVEPGLGDVSELSGESSAADSKK KAAAKTAAPSESETEKADTETREKEDKPKEEEAKEPAVEEKPKPRSSQPKEASPAFMSTV FAILDVYLNKILNYLARNFYNLRFLALFVCFAINFILLFYKVTGEAEEEEEDEENRWGDD DDENTLFDMDEFVLQESTGYMLPTLRFLAIFHTVISLLCLVGYYCLKVPLVVFKREKEIA RKLEFDGLYITEQPSDDDIKGQWDRLVINTPSFPNNYWDKFIKRKVINKYGDMYGAERIA ELLGLDKSALDFDPTVETVEKEASLLSWLSSIDTKYHIWKLGVVLTDNYFLYLIWYTTMS IFGHFNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFF RKFYNKSEDEDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDELEDPAGDPYELYRILFDIT FFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDRTPHGFETHT LQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYEDQLG NT seq 14577 nt NT seq  +upstreamnt  +downstreamnt atggctgagggcggagaaggggaggatgagatccagttcttgagaactgacgatgaggtg gtgctccagagcgtggccaccatccagaaggagcatcgcaagttctgcctggccgcggag ggactcgggaaccgcctgtgttacttggaacccacctctgaagccaagtatgttcctcca gacatgtgcatttgtaactttgtgctggagcagtcgctgtcggtccgcgccctgcaggag atgctggctaacaccggagctagcagcgaagggaaagccgaccatgaaaaatggaggtta attaaaaaggcgggtcagggaggcggacaccggaccctgctctacggtcacgccatcctc ttacgtcactccttcagtgacatgtacttgacctgtttgaagacatcaaggtctctgaca gacaagctgtcatttgatgtcggactgcaagaagattcagtaggagaagcctgctggtgg acgattcatccggcgtccaagcaaagatcagaaggagagaaagtccgcattggagatgat ctgattctcgtcagcgtgtccactgagagatatctgcatctctcgaactgtaacggcaac attcaggtagatgcctccttcatgcaaaccctctggaacgtccagcctacgtgttcgtca ggcagcatggctgtagggtatttgattggcgggcatgtgatgcgtctctgtcatggtcac gacgagagcttgacgatccctggagcagataagagtgaagaggagcaaagaatagtgaac tacgaggcggggaagggagcgtcaagagcccgctccctgtggagactggagcctctcagg atcagctggagcggcagccacattcgatggggccagtctttccgtctgcgtcatctctcc actggtcgctatctggccttgactgaagaccgtggtttggtcctggaggacagagagaag tgccacaccaaagccactgctttttgctttaagccatccaaggaaaaaggcgattctggc atgaagagggatattgacgggatgggagtccccgagataaagtacggtgactccgtctgt tttgtcatgcacgtggccactggactgtggctgtcctacctggcacctgatgccaaatcg tctcgtcttggtcccctgaaaagaagggcctgccttcactctgagggccacatggatgat ggtctcatcctgcagcgctgccagcatgaggagtctcgggctgctcgcatcatccgaaac accacattcctcttcagaaacttcataaaggcactggacagcgctgcagccggagagacg aatgcggtggccggatatgttgaagaggtgctgcagacgctgaacgatctgattgaatat ttcaagcagcccgacgtagatctagagcacgaggaaaaacaggcgaggcttcgctcactc atcaaacaacaagacctcttcaaggaggagggtatgctggccctgctctccaaatgcatt gaccggatgaacctgtatgatagtgcggcccacttcggagagatggccggggaggaagct ggtgcagcgtggaaggacatcctcaacctcctctatgaactcctggctgcactgattcgt ggaaaccggaccaactgcacccagttctcccgaaacttggactggctggtcagcaaactg gaaagaatggagtcgtcatcaggaatcctagaagtcctccactgtatcttggtggaaagt ccagaagccctgaacatcattcagaaaggtcacattaaatccataatttctcttctctac aagcatggacgcaaccacaagattctggatgtgctgtgctctctgtgtgtgtgcaatggg gtggcagtgagaaccaatcagaatctgatctgtgacaacctgctgccaaagagggacctg ctgctccagaccagactggtcaacgatgttcaaagcatgaggcccaacatcttcctgggc atcgctgaaggttcggctcagtataagaagtggtactacgagttggtcatcgaccaggtg gaccactttgtgaccggagagccgacccacctgagagtgggttgggccaacaccaaaggc tacgctccgtatcctggcggaggagagggctggggtggaaacggcgttggggatgacctt tactcctacagctttgatggacttcatctgtggtcaggtcggatccccagagccgtggcc tccattaaccagcacctgctgaactcggacgacgtggtcagttgctgcttggatctgggc gctcccagcatgtccttcaggatcaacgggcagccggtgcagggcatgtttgaggacttt aacacagacggattcttcttccctgtcgtcagcttctctgctggagtgaaagcccgtttc ctgctgggtgggcgccacggagactttaagttcctgccgccagccggttactctccgtgc tacgaagcgctcctgcccaaggagaagatgcatgtggagcctgtgaaggagtacaagcgg gaccatgacggggtccgtgacctgctgggaaccacccagttcctgtcccaggcctccttt attcccactccggttgacaccagccagattgttctgccgcctcatctggagaacatccgc gacaagttggcagaaaacatccacgaactttggggaatgaataagatcgaactgggctgg acgtatggcaaggttcgcgacgacaacaagaggcagcacccttgtcttgtggatttcagc aagctgcctgaaactgaaaagaactacaacgtgcagatgtcaagcgaaacactcaagacg ctgttggcacttggctgccatgttgcccaggttaatgttcacgctgaagaggacctgaag aaaatcaaattaccaaaagactacatgatgtctaatggatacaagcctgcgccactggaa ctctctgacgtgaaactgactccaggtcaagaggttctggttgataaactggccgaaaac gcacacaacgtttgggccaaagacagaatcaaacaaggatggacctatggcatccagcag gatgtgaagagcagacgtaaccctcgcttggtgccatatgctttattggatgaacgcaca aagaaatctaacagagacagtctgagagaggccattcggacgatggttggatacggatat gacatcgaccctccagaccaggaggttgtgcatgcaatagacaatcagagcatcgagaca atccgctttttccgtgtggagcaaacgtacgccgtgaagaccgggaagtggtactttgag tttgaggtcctgagcggaggcgacatgagggttggctgggccaggccaggctgcaggccc gacgtggagctgggaaccgatgaccaggcctacgtctttgatggatacaggggtcgacgg atgcatgctggtagccgttactttgggcatccgtggaagaagggcgacgtggttggttgc atgatcaacatggaggacaaatccatgattttcactctgaacggagagctcctgatcacc agcaagggctctgagctcggcttcgctgactttgaaacagaggatggttttattccggtg tgcagcctcgggatgtctcagatcggccacatgaacctcggaaaggacgccagcacgttt aagtactacaccatgtgtggcctccaggagggcttcgagccctttgctgtcaacatgaac agggagataaccatgtggttcagcaagcgtttgcccacctttttcaacgtaccccaggac cacatgcacatcgaggttaccaggattgacgggacagtggacagccccccgtgtctcaag gtcacacataagacgtttggcacccagaacagcaacagcgacatggtttactgcaggctg agcatgccggtggagttctactctgcagacaggctgctggacgagtcgctgaagctcagc caacctcccaaagaagatggaagtattgactatggaagcatcacaacctactaccactca gtgagagtgtttgccggacaggaccctggcagcgtgtgggtgggctgggtcacaccagac tatcactactacagcaagaacttcagtctcagcaagacgcaaactgtcaccgtcaccctg ggagacgagcggggccgggtccacgagagtatccagaggagcaactgctacatggtctgt gcagcagatgcactcggcccgtcttcctccagccgctcaaacaccgacctggaaatcggc tgtctggtcgacttggccaccggcctcgtctccttcaccgccaacggcaaagaactgcct acagcgtatcaggtggagccgaacaccaagctgttcccggctgtgttttgctgccccacc agttccaacctcttccagtttgaatttgtcaaaataaaggatgccatgccgctgtcgtca gccatgttcagaagtgagcagcggaacccggttcctcagtgtccgccgcgtctggatgtg caaaccatcgtggccgtgctttggagccggatgccaaacaccttcctgaacgtggagacg gctcgggtcagcgagcggcacggctgggtggtgcagtgtctggagcctctgcagatgatg gccgtgcacatacctgaagagaacaggtgtttggacatcatggagctgtcagagcatgaa gacctaaggaagtttcactcccacactctgaagttgtactgcgccctctgtgctctggga aacacgcgtgtggctcacgctctctgcagccacttagaccaatcacagcttctctacacc atcgacaaccagtacctgtcgggcatgctcagagaaggcttctacgacgtcctcatcagc attcatcttgagacggcgaaagaggcacggctaatgatgaacaacgaattcatcatccct gtgacggacgagacccggtccatcaagctgttcccagatgaatctaagcggcattctctt cccggagtcggcctgagcacttccctcaaaccccgagtcaacttctccccggtcggcatc atcagcaccaaacgccaccagctcctctacagcccccagatccccctgggcattctgaag gagaaagccatcagcatgctgacggaggccgtgcagggaggaggctcccacatccgagac ccggtaggcgggagcctggagtaccagttcgtccccatcctgaagctcatcggaacgctg ctcatcatgggagtgctgaccagcgacgaggtgaggctgattctcctcctcatcgagccc aacgtgtttggggaggccaaggagggagaagaggggagcgaggtcgtggtggcgggggag aaagaggaggtgagcaagaacgaggagaaggctgtggaggcgggagaggaggagaccaag gagagcaaaccggccgccaaaggcctgctggagaagtccctgccggagtctgttaaacgc cagatgtgcgagctgctgcactacttctgcgactgtgagctgcagcaccgcatcgaggcc atcgtctccttctccgaccgcttcgtctccaaactgcagtacaaccagaagtttcgctac aacgagctgatgcaggctttcaacatgtctgccgccgtcacggccaagaagaccaaggag tttcgctcgccgccacatgaacagatcaatattctgctgaacttcagcgcaggggaggac tgcccttgtcccgaggagatccaggatgaactcacgtctttccatgaagaattacggctg cactgtggaatccctgtggaggaggaggaggaagagcaggacacgtcgattaaaggtcgg ctcctggctctgctctacaagatcaagggcccgcctcagaagacagaggaggagcccgca gagacagaacaggccgctccgaccaacctgaaggagctgatttctcagacgatcaccagc tgggcccaggagtcccacatccaggacccggagctggtccgagtcatgttcagcctgctg aggaggcagtatgacggcatcggcgaactgctgcgggccatgaagaagtcatacaccatc agcgccgcctcggtgcaggacggcatcaatctgctggcctctctgggtcaaatcaggtcg ctgctttcagtgcgcatgggcaaggaggaggagaagctcatgatcgatgggctcggggac atcatgaacaacaaggttttctaccagcatcccaatctgatgagagttttgggaatgcat gagacggtcatggaggtcatggtcaacgtcctgggtggagacaagtcccaggagattgcc tttcccaaaatggtggccagctgctgtcgatttctgtgctatttctgccgcatcagccgg cagaaccagaaggccatgtttgaccacctgagctacctgctggagaacagcagcgttgga ctggcgtctgaagcgatgcgaggctctactcctctggatgtcgcagcatcttcagtgatg gacaacaacggtctggctttagctctggaggaacctgacctggaaaaggtggtgatgtac ctggcaggatgcggcctgcagagctgtgccatactggttgccaagggttacccggacctg ggctggaaccccatagagggagagcgttacctctcattcctgagatttgtcgtcttctgc aatggtgagagcgtggaggaaaatgctaacgtggtggtgaagctgctgatccgacgtccc gagtgcttcggccccgccctgagaggcgaggggggacaaggtcttctggctgcgatgaag gaggccatcaagatctctgaggatcccgcgctggacctgcccaagagcccggctggagcc accgcagggtctggtgaagaggaaggagaagttatccacatgggcaacgccatcatgtcc ttctactccgccctcatcgacctgctgggacgctgcgctccagagatgcatcttatcaat gcagggaaaggtgaagcgttgcgtatcagagccatcctgcgctctctggttcccacgtca gacctggtgggcatcatcagcatccccctcaagatgcctgtgattaacaaagacggatcc gtgacagaacctgacatgtcggcctgcttctgcccggaccacaaggcccccatggtgctt ttcctggacagagtttacggcattgaggaccagagtttcctgctgcagatgctggaagtt gggttcctgccggacctcaaggcctcggcgtctctggacacggaagtactgagcaccacg gagacagcgctggccatgaatcgctacatcggttcagctctgcttcctctgctgacccgc tgcgccgctctgttcggcaacacggagcactacgcacatctggtcgactccacgctggag accatctatcggctgtccaaaggtcgctcgctcactaaagcccagcgggacgccattgag gagtgtctgctggccatctgcaagcatcttcgaccatccatgatgcagcagctgctcagg cgcctcgtcttcgatgttcctctgctcactgaatactgcaagatgcctctccggctgctg accaaccactatgagcagaactggaagtactactgcctgccgtctgggatgggcggcttc ggcatggcctctgaggaagagctgctgctcacaaagaaactcttctggggaatttttgac tctctttctcagaagaaatatgattctgagctgtttaaaatggccaagtcgtgcctgtgt gccattgctggagctttgcctccagacttcgtggacaccagcttaggggccacggtggag aagcaggagtcggtggatgcacagggaaactttgagcccaaacccatcaacactgccaac atctcccttcctgaaaaacttgactacattgctaataagtatgcagagcattcccacgac aagtgggcttcagagaagatgtcggctggctggaaacacggagacagtttggacgagcag gccaaagcccatccgctgctgaagccgtataaatctttaagtgagaaggagagggagacg taccgctggcctgtgaaagagtccctgaagagcatgctggcgatgaactggaacattgag aggaccaaggagggagaagccatgttccagcagcgagagagtgaaaaacagaggaagctc tcagaaactcagtctaacggattcagtcctgctccgatggacctgcacaatgtcactttg tcccgagagttacagagtatggtggaagtggttgcagaaaattaccacaacatctgggct aagaagaagaagtcagaacttctgagtaaaggaggagggttggctcacccgctgcttgtt ccctatgataccctgactgctaaagagaagtacagagacaaagaaaaggcccaagagctc ttcaagttcctgcagataagtggctatgctatcacaagaggtctgaaggacatggagcag gactcgtcatccatggaaaaacgttttgcctacaagttcctaaagaggctgctgaagaat atcgactctgctcaggagtttatcgcccatctggaggcgatggccaccagtgggaaaact gacaagtccccccatgaccaggagatcaagttctttgcaaaggttttacttccattgatt gatcagacatttaagaaccactgcctttacttcctgtccacacccagcaagaacctgagc agctgtggttgcgcctccaacaaggagaaggagatgctcacgagcctgttctgtaagatg gcagctcttgttagacacaggatttctctctttggaagtgactctgcgatcatggtgagc tgtcttcacatcctgtcccactcactcgacacgagaacagtgatgaaatccggcgcagag ctggtcaaagtcggcttcaaggccttctttgagaacgcggcggaggacttggagaagctg gtggagatgctgaagctggggaagttcatgcagtcgcgcgcgcagatgaagagcgtcact cagagcatcaactatgtgaccgtggccctgctgcccatcctcactgccctgtttgaacac atcaggacgtatgagtttgacgtggacctgctcgtggatgatgtgcagctgtcctgctac cgaatcctgatgtgtttctacagcctgggaaccggaaagaatgtctttgtggagaggcat ctgccagcgattggggagagtctggcgatcttggtgggagcgatgccggtggcgttcctg gagcctcatcttaacgcccacaacccactttcagttttcaacaccaagacagcccgagaa cgagccatcctgagcatgcccgacacggtggaggagatgtgtccagaaatgcctcgcctc gacaagctgctcaaggacgtcaatgacgtgtcggagtgcggcgctcgctacagtgacatg ccacaggtcattgaggtcgtcctccccatgctgtgcaactacttgtcctactggtgggag aaaggcccggagaactcgccgccggacaccgactgctgcaccatggtgacgtctgaacac ctgagcatcattctgggaaacatcctgaagatcctcaacaacaacctgggcattgatgac gctccctggatgaagaggattgcagtttactcgcagccaatcatctgcaaagctggagct gatttgttgagaacccactttctgcccacaatggagaaactgaagaagaagacggtgaag gttgtgtctgaggaggagctgctgaaggccgatgggaaaggagacaaccaggaagcagag ctgctcatcctggacgagtttgcagtgctctgcagggacctctacgctttctaccccatg ctcatccgctacgtggacaacaacaggtccaggtggctgaaggagccggatgcagactcc actgagctcttcaggatggtggctgagattttcatcctctggtgcaaatccaacaacttc aagcgtgaggagcaaaactttgtgattcagaacgagatcaacaatctgggcttcctgacc ggggagggcaagtccaagatgtccaagtctggtggagaccaggagcggaaacataaacgg cgccgcggtgaatattactccatccagacgtctctgatcgtagctgcgctcaagaagctg ctgcccatcggcttgaacatgtgcacaccgggagaccaggagctcatctctttggcaaag attcgctacagcctgaaagacacggacgatgaggtgaaagagcatttgcgtcagaacctc cacctgcaggaaaagtctgatgatccggcagttcactggcagctgaacctttataaagac gtagtggtgaaatcggaggagccgtcggattcggagcacacggtggacagaatccagagc atctctgcagctgtctttaatttggagcaggtggaacagcctctgaggaacaagaagtgc atcgtccagaagctgctgtccaagcagcgtaagcgagccgtcgttgcttgtttccgcatg gctccactctacaacttacccagatacaaaaataataattacttcctgaatggctatcgg gaggtttggctggaaagggcgttcaaagcctccagctttgaccgcctgttctccctgctg acgaaaacaccgatgaagatcgtggaggaagaggaggaggaggtggctgagatcaagccg gatccgctccaccagctcatcctccacttcagccacaacgctctgacagagagaagccac ctggaagttgatcctttatatattgcatatgcagacatgatggcaaagagctgtgcagag gatgaggaggaagaggaagaagaagggcgggaaaagacttttgaggaaaaggagatggag aagcagaagatcctgtatcagcaggcgaggctgcacgcgcgtggggctgcagagatggtg ctgcagatgatcagcgccagcaaaggtcgtctgggccccatggtgacctgcaccctcaaa ctgggcatctccatcctaaatggaggcaacgtgcaagttcaacagaaaatgctcggttac ttgacggacaaaagagacgcaggctttttcaagagtctgtcaggactgatgcagtcgtgc agtgtcctggatctgaatgcatttgagaggcaaaacaaggcagaaggacttggcatggtg acggaagaaggttcaatcaacactcagcggggctccaaggtgcttcagaacgacgaattc accaaagatctgttccgctttttgcaacttctctgtgagggacacaacggagatttccag aacttcctgagaacccaaactggaaacacgaccacagtgaacatcatcatcagcactgtg gactacctgctccgcctccaggaatcgatcagtgatttttactggtattattctgggaaa gatgtaattgatgaaactgggaagcacaacttctccaaagctttatctgtagccaagcag atttttaactcgctcactgagtacattcaggggccttgcattggaaaccagcagagttta gctcacagcagactgtgggatgcagtcgtcggcttcctgcatgtgtttgcaaacatgcaa atgaagctttcacaggatgccagtcagattgagttgttgaaggaactgatggatttacag aaggacatggttgtcatgctgctgtctctccttgagggaaacgtggtgaacgggacaatt gggaagcagatggtcgacactctggtggagtcttccagtaacgtggagatgatcctgaag ttcttcgacatgttcctcaaactgaaagacctcaccacgtccgacaactttaaggagtac gacccggaatgcaaaggcattatttccaagaaggagttccagaagtcgatggagagccag aagcagtacaaccagtcagaaatcgagttcctgctgtcgtgcgcggaggccgacgagaac gacatgttcaactacaaggagtttgtggagcgattccacgagccggccaaggacatcggg ttcaacgtggccgtgctgctgaccaacctgtccgaacacatgccgcacgacgcccggctc gccaccttcctggacctggccgaaagcgtcctcagctacttcgagccgtacctggggcgc atcgagatcctgggcagcgccaagcgaatcgaacgcgtttacttcgagatcagcgagtcg agccgtgagcagtgggaaaagccgcaggtgaaggagtccaagcggcagttcatctttgac gtggtgaacgagggaggagagagcgagaagatggagatgtttgtgaacttctgcgaggac accatctttgagatgcagctggcctcgcagatctccgagccggacgccgtggagcagccg gaggaggaggaggaggaagaggtgcacaacatcctggaggagctttctgggggagacgcc gccgccctggagtccacctcggcgttcaccaccgcctgtcgttcggtcaagaagagcctc tcagaaatccggcagatcttcaccattaaaacggcgcgcaagcagttcaagaaaatcaag aagctgagcatcaaggagctgatcaccggcttcttctccttcttctggatgatcttcatc ggcttctttaaggggattatcagcctcgtgttcggtttcttccacgtcatctggtcatcc atgttcggcggagggcttgttgaaggagccaagaacataaaggtgacggacatcctgggc aacatgccggacccgacgcagttcggcatccacggcgacgtgggggaaggagacaaagtg gaagccatggagtcgtcgggcagcttggacaaagccatggctcctgcaggagacgccact gaggtggacgtgatgctggagatgctgacgcctaagaaggagggagggaaacacgtggag cccggcctgggggacgtgtcggagctgagcggggagtcctccgctgcagacagcaagaag aaagccgctgccaagacggctgctccctctgagagtgagacggaaaaagcagacacagag acccgggagaaggaggacaaaccaaaggaggaggaggcgaaggaaccagctgtggaggag aaacccaaacccagatccagtcagcccaaagaggcgtctccggccttcatgtcaaccgtc tttgccattcttgacgtctatctgaataagatactgaactacctggctcgtaacttctac aacctccgtttcctggctctgtttgtttgcttcgccatcaacttcatcctgctcttttac aaggtcactggtgaagctgaggaagaggaggaagacgaggagaaccgctggggtgacgat gatgacgagaacacgctgttcgacatggacgagtttgtgctgcaggagagcaccgggtac atgctgccgacgctgcgcttcctggccatcttccacaccgtcatctcgctgctctgcctg gttggctactactgcctgaaggttcctctcgtggtgttcaagagggagaaggagatcgcc aggaagctggagtttgacggtttatacatcactgagcagccgtccgacgacgacatcaag ggccagtgggatcgactcgtcatcaacacgccatcttttcccaacaactactgggacaag tttatcaagcgcaaggtgatcaacaaatatggcgacatgtatggggcggagcgcatcgct gagcttttgggtctggataagagcgctctggactttgaccccaccgtggagacggtggag aaggaggcgtccctgctgtcctggctgagctctattgacacaaagtaccacatctggaaa ctgggagtggttttgaccgacaactacttcctgtatctcatctggtacaccaccatgtcc atctttggacacttcaacaacttcttctttgctgcacatctgctggacatcgccatgggc ttcaagacgctgcgcaccatcctgtcctccgtcactcacaacggcaagcagcttgtgctg accgtcggtctgctggccgtggtcgtctacctctacactgtggtggccttcaacttcttc agaaagttctacaacaagagcgaggacgaagacgagcccgacatgaagtgtgacgacatg atgacgtgctacttgttccacatgtatgtgggggtgagagccggcggaggcatcggagac gagctggaggacccggccggagatccctacgaactctaccgcatcctgtttgacatcacc ttcttcttcttcgtcatcgtcatcctgctggccatcattcagggtttgatcatcgacgcc tttggggagctgagagaccagcaggagcaggtcaaggaggacatggagaccaaatgcttc atctgcggcatcgggaacgactactttgatcggacgcctcacgggtttgaaactcacacc ctgcaagagcacaacctggccaactacctgttcttcttgatgtacctaatcaacaaggat gagactgaacacacgggtcaggagtcgtacgtgtggaagatgtaccaggagagatgctgg gacttcttcccggcaggagactgcttccgcaagcaatacgaggaccagctgggctag

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