Phyllobacterium meliloti: LLE53_002140
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Entry
LLE53_002140 CDS
T11258
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
pmel Phyllobacterium meliloti
Pathway
pmel00300
Lysine biosynthesis
pmel00550
Peptidoglycan biosynthesis
pmel01100
Metabolic pathways
pmel01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pmel00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LLE53_002140
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LLE53_002140
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LLE53_002140
Enzymes [BR:
pmel01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LLE53_002140
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
UGX86695
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All DBs
Position
459014..460447
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AA seq
477 aa
AA seq
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MSFLWTSEAMIEAMNGRPVGTLPEGITGISIDTRTLRKGEAFFAIKGDALDGHDYATAAV
AAGAALLVVAEVKLPALGKLKTPMIVVDDVLAAMTRLGLAARERSHAQIIAVTGSVGKTT
TKEALRHVLANAGNVHASVASFNNHWGVPLTLARMPEDTDYGVFEIGMNHADEIRPLVKM
VRPHVAIITLIAPAHLGHFKNLQEIATAKAEIFEGLVPGGYALLNRDDKHYKFLEKLAVD
AGVEHIKTFGENARADYRLRALKLHGECSCMTARLAGSEVVVKVGAPGRHIVQNVLAVLG
AAHLTGADMTKVTLALASLKPDSGRGARHTLEIGRGTFTLIDESYNANPASMRAAIELLA
AAVPTGRGRRIAVLGDMLELGKQAPKLHAELAPVIAANHINMVFLGGPEMAALKAALPVE
IHAEYRQSVDELQSNLLSTIRAGDVIMIKSSKGTGFARIVKAILQKYNTVEPVGPAE
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
atgagtttcctctggacctcggaagcgatgatcgaggccatgaacggcaggcctgtcggt
acgctgccggaaggcattaccgggatttccatcgatacgcggaccctgcgtaagggtgag
gcgttctttgccatcaagggcgatgcgcttgatgggcatgattatgcaaccgctgcggtt
gctgctggcgctgctctgctggtggttgcggaagtgaagctcccggcgctgggcaagctg
aaaaccccgatgatcgtggttgacgatgtgctggcggccatgacacggcttgggctggca
gcgcgcgagcgctcgcacgcccagattattgcggtgacaggttccgtcggtaagacaacc
accaaagaagcactgcggcatgtgcttgccaatgcgggcaatgtgcatgcatccgttgcc
tcgttcaacaatcattggggtgtgccgttgacccttgcgcgcatgcctgaggatacggat
tacggcgtctttgaaatcggcatgaaccatgcggacgagatcaggccgctggtgaaaatg
gtgcgcccgcacgtggcgatcatcacgctgattgctccggcgcatcttggccatttcaag
aacctgcaggaaattgccacggcaaaagccgagatttttgaaggacttgtgcccggcggc
tatgccctgctcaatcgcgatgacaagcactacaagtttctggaaaagttggcggtggat
gcgggcgtcgagcatatcaagacctttggcgagaatgcccgtgccgactatcgcttgcgc
gcgctcaaactgcatggcgagtgctcctgcatgacggcgcggcttgccggttccgaggtt
gtggtcaaggtcggcgctccgggcaggcacatcgtgcagaatgttctggcggtgctgggt
gctgcgcatctgaccggtgctgacatgaccaaggtcacgctggcgctggcatcgctgaaa
cctgacagcggccgcggtgcccgccacacgctggagatcggccggggtacattcacgctg
atcgatgagagctacaatgccaatccggcatcaatgcgcgcggccatcgagcttcttgcg
gctgccgtaccgacgggcaggggccgccgcatcgccgttcttggcgatatgctggagctt
ggcaaacaggcaccaaaactccatgcggaactggcgccggtgattgcggccaatcatatc
aacatggttttcctcggtggacccgaaatggcggcgttaaaagcggccttgccggttgaa
atccatgccgaatacaggcagagcgtcgacgaattgcagtcaaatctgctgagcacgatc
agggccggtgatgtgatcatgatcaaatcatcgaagggaaccgggttcgccaggatcgtg
aaggcaattctacagaagtacaacaccgtggagcccgtcggtcctgccgaatga
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