Proteus mirabilis BB2000: BB2000_1893
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Entry
BB2000_1893 CDS
T02789
Symbol
folC
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
pmib
Proteus mirabilis BB2000
Pathway
pmib00790
Folate biosynthesis
pmib01100
Metabolic pathways
pmib01240
Biosynthesis of cofactors
Module
pmib_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
pmib00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
BB2000_1893 (folC)
Enzymes [BR:
pmib01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
BB2000_1893 (folC)
6.3.2.17 tetrahydrofolate synthase
BB2000_1893 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AGS60368
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Position
complement(2041473..2042726)
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AA seq
417 aa
AA seq
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MWLSYLEHLHSSAIDMGLERVGKVGQLLNVLRPAPKVITVSGTNGKGTTCHMLESILMAS
GLKVGVYSSPHLVRYTERVRIQGKELSPADFCQVFAEIEQTRGDISLTFFEYGTLAALKL
FQQAQLDVVILEVGLGGRLDATNIVDADIAAITSIALDHTDWLGADREHIGHEKAGIFRK
NHYAVVGEPDMPLSIAQVAQQKQAKLFRRGVDWSFSIDGDHWHWRSADKQFEKLPIPNIP
LANAGTAMAVIRCLLKTDDKVSQGITHQSIVEGMSKAQLPGRFQIISQHPLVIFDVAHNP
HAAGYLAEKLAQLPRYSDTKVRIVVGMLGDKDIAGTLACLSPQADQWYVAPLNEFRGASA
QVLAQHLDYPAVFDSVEQAWQQAISEAQKNDIVVVCGSFHTVAHVMELLEKESASGK
NT seq
1254 nt
NT seq
+upstream
nt +downstream
nt
gtgtggctttcttatcttgaacacttacactcaagtgctattgatatgggacttgagcgc
gtgggcaaggtaggtcaattactgaatgtattacgtcctgcccctaaagttatcactgta
tcgggtactaatggtaaaggaaccacttgccatatgctcgagtcaattttgatggcttca
ggattgaaagtgggggtttatagttcacctcatcttgtccgttataccgagcgtgttcgc
attcaaggtaaagagctttcaccagctgatttttgtcaagtatttgctgagatagagcaa
accagaggcgatatttcgctgactttttttgaatacggcacactcgccgcattgaaacta
tttcaacaagctcagcttgatgtggttattcttgaagttgggttaggggggcgtttagac
gcgaccaatattgttgatgccgatattgcagctatcaccagtattgcccttgatcatacc
gattggttaggggctgatagagagcatattggtcatgaaaaagccggtatcttccgtaaa
aatcactatgctgttgtaggcgagccagatatgccactgtctattgcacaagtcgcgcaa
cagaaacaggctaagttatttcgtcgtggtgttgattggtcattttctattgatggtgat
cactggcattggcgtagtgcagataagcagtttgaaaaacttcccatccctaatattccc
ttagccaacgcaggtacggcaatggcagtaatacgctgcttattgaaaaccgatgataaa
gtgagtcaagggatcacccatcaaagtatcgttgagggaatgagtaaagctcagttgccg
ggacgttttcagataatttcgcagcatccattagttatttttgatgttgctcataatccg
catgctgctggatatttagccgaaaaattggcgcaattaccgcgttattctgataccaaa
gtgcgcattgttgttggtatgctgggtgataaagatattgcgggtacattagcatgttta
tcccctcaagccgatcagtggtatgttgcaccattgaatgagtttcgtggcgcatcagcc
caggtattagctcagcacctcgactatccggcagtatttgatagtgtcgagcaagcatgg
caacaagcaatatctgaggcacaaaaaaatgatattgtggttgtatgtggatcattccat
accgttgctcatgtaatggaactattggaaaaggagagtgcgagtggcaagtaa
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