Prochlorococcus marinus subsp. pastoris CCMP1986: PMM1066
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Entry
PMM1066 CDS
T00142
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
pmm
Prochlorococcus marinus subsp. pastoris CCMP1986
Pathway
pmm00290
Valine, leucine and isoleucine biosynthesis
pmm00620
Pyruvate metabolism
pmm01100
Metabolic pathways
pmm01110
Biosynthesis of secondary metabolites
pmm01210
2-Oxocarboxylic acid metabolism
pmm01230
Biosynthesis of amino acids
Module
pmm_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
pmm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
PMM1066 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
PMM1066 (leuA)
Enzymes [BR:
pmm01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
PMM1066 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
CAE19525
UniProt:
Q7V121
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Position
1007864..1009504
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AA seq
546 aa
AA seq
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MSKDPGRILIFDTTLRDGEQSPGASLNLEEKLAIAHQLARLGVDVIEAGFPFASPGDFKA
VNKIAEVVGGENGPIICGLARASTNDIKACYEAISPAPKKRIHTFIATSDIHLKHKLRKT
RSDVLCIVPEMVSYAKSLVDDIEFSCEDASRSDPEFLYEVIQLAITSGATTINIPDTVGF
TTPSEFGKLIFDINKNVPNIDEAIISVHGHNDLGLAVANFLEAAKNGARQLECTINGIGE
RAGNASLEELVMALHVRKSFFNSFFGRSSDSPTPLTAIRTEEITKTSRLVSNLTGMNVQP
NKAIVGANAFAHESGIHQDGVLKNRLTYEIIDAKTVGLNDNKISLGKLSGRSAVRARLEE
MGYDLSREDLNDAFARFKELADRKREITDRDLEAIVSEQVQLPESKFQLSHVQVSCGSTS
KPTATVTLINTEDHTEDTAVAIGTGPVDAVCEALNALTKVPNELIEFSVKSVTEGIDALG
EVTIRIRNKNKIYSGHSADTDVVVAAANAFVNALNRLVFSEKKNSIHPQFDDLENPKNKV
LSNPKK
NT seq
1641 nt
NT seq
+upstream
nt +downstream
nt
atgtccaaagatcctggcagaatattgatctttgatacaacactgagagatggtgagcaa
tcccctggcgcgagtttaaatcttgaggaaaagcttgcaattgcccatcaacttgcaaga
ttaggagtagatgttattgaagcaggatttccatttgctagtcctggagattttaaggcc
gtaaataaaattgctgaagtagttggtggagaaaatggtccaataatttgtggtttagcc
agggcttctacaaatgatataaaagcttgttatgaagctataagcccagcccctaaaaaa
agaattcatacatttatagccactagtgatatacacctaaaacataaacttagaaaaaca
agatcagatgttctttgtatagttcctgaaatggttagttatgctaaatcgttagttgat
gatattgagttctcttgtgaagatgcctcaaggagtgatcctgaatttctttatgaagta
attcaactagcgattacatcaggagctacaactataaatattccagatacagttgggttc
acaactccaagtgaatttgggaagcttatttttgatattaataaaaatgttccaaatatt
gatgaagctattatttcagttcatggtcataatgatttaggtttagctgtagctaatttt
ttagaagcagcaaagaacggagctaggcaattagagtgcacaataaatgggataggtgaa
agagcagggaatgcctctttagaagagttagtaatggcattacacgtgaggaaaagtttt
tttaatagtttctttggaagaagttcagattcaccgactccattaacagccataagaaca
gaagaaatcacaaaaacttcgagattagtatctaacttaactggaatgaatgttcagcct
aataaggcaattgttggagcaaatgcttttgctcatgagtcgggaatccatcaggatggt
gtactaaaaaatagactcacatatgaaattattgatgcaaaaactgttggtttgaatgat
aataaaatttcattagggaaacttagcggaagaagtgccgtaagagcaagattggaagag
atgggatacgatttaagtagagaagacctgaatgatgcttttgctcgtttcaaagaactc
gctgatagaaaacgagaaattactgatagagatttagaagctattgttagtgaacaggtt
caacttcctgaatctaaatttcaactaagccatgttcaagttagttgcggcagtacatca
aagcctaccgcgacagtaactcttataaatacagaagatcatactgaagatactgctgtc
gcaataggtactggacctgttgatgcggtttgcgaagcgctaaatgcattaactaaagtt
cctaatgaattaatagagttttcagtaaaatctgtaacggaaggaatagatgcactaggg
gaagttactataagaattcgtaacaagaataaaatatattcaggccattctgcggataca
gacgtagttgttgctgctgcgaatgcttttgttaatgctttaaacaggcttgtattttca
gagaagaaaaactctattcacccccaatttgatgatttagaaaatcctaaaaataaggta
ctatcaaatcctaaaaaatag
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