Proteus mirabilis HI4320: PMI1745
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Entry
PMI1745 CDS
T00753
Symbol
menD
Name
(GenBank) menaquinone biosynthesis protein mend [includes: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase and 2-oxoglutarate decarboxylase]
KO
K02551
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:
2.2.1.9
]
Organism
pmr
Proteus mirabilis HI4320
Pathway
pmr00130
Ubiquinone and other terpenoid-quinone biosynthesis
pmr01100
Metabolic pathways
pmr01110
Biosynthesis of secondary metabolites
pmr01240
Biosynthesis of cofactors
Module
pmr_M00116
Menaquinone biosynthesis, chorismate (+ polyprenyl-PP) => menaquinol
Brite
KEGG Orthology (KO) [BR:
pmr00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00130 Ubiquinone and other terpenoid-quinone biosynthesis
PMI1745 (menD)
Enzymes [BR:
pmr01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
PMI1745 (menD)
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Motif
Pfam:
TPP_enzyme_M_2
TPP_enzyme_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
CAR43639
UniProt:
B4EZ42
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Position
complement(1867528..1869213)
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AA seq
561 aa
AA seq
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MSNSSFNRQWAKVILETLTRHGLRHICIAPGSRSTPLTLAAAANHKLICHTHFDERGLGH
LALGLAKATQQPVAVIVTSGTAVANLYPALIEAGLTGERVIFLTADRPPELINCGANQAI
RQQGIFASHPSETLSLPRPTADISARWLVSTLDNAMNNLVHGALHVNCPFAEPLYGDDIE
HDTPWTQALGKWWQSDKPWLQETLSPSVTTHPQWDRLRQKKGVVIAGRISAKEGIAVAKW
ASKLGWPLLGDVLSQTGQPLPCADLWLNNPQVKAELNQAEIVIQFGSSLTGKRLLQWQAN
CSPQMYWVIDAIPGRLDPGHHQGEKFTLSPSQWLTAHPAIDNLPWALSLSHIATQTYQHV
TEVTDYFGEAQVAHQLDHLLPHNGQLFVGNSLIVRLIDAFAQLPQGYPVMSNRGASGIDG
LLSTSAGVHRATQKPTLTILGDLSALYDLNSLALHQQVYAPNVVIIVNNNGGQIFSMLPT
PMAERERFYCMPHALNFKHAAAMFGLDYVAPNCWDDLFTTVTACWQGEAKTTLIELIVNE
TEGAETLNQLVKQVTAYDFSL
NT seq
1686 nt
NT seq
+upstream
nt +downstream
nt
atgtctaatagttcgtttaatcgccaatgggctaaagttatactggaaactttgactcgt
catggtttacgtcatatctgtatcgcacccggatcacgttcaacgcctttaacgcttgcg
gcagccgccaatcataaacttatttgtcatacgcatttcgatgagcgtggtttaggtcac
ttagcattaggtttggcaaaagccactcaacagcctgttgcagtgattgtcacctcaggt
accgcagtggcaaacttataccccgctttaattgaagcgggacttactggtgaacgggtg
atctttctcacggcagatagaccgcctgagctgattaattgtggcgccaatcaggctata
cgccaacaaggtatttttgccagccatccctcagaaacactctctttaccacgccctaca
gcagatatttctgctcgttggctggtttctacattagataatgccatgaataatcttgtg
catggtgctttgcatgtaaactgcccttttgcagagccattatatggtgatgatatagag
catgacacaccatggacacaagcattaggaaagtggtggcaaagtgataaaccttggtta
caagaaacgctttctccctctgtgactacacaccctcaatgggatcgactacgtcagaaa
aaaggggtcgttattgctggacgtattagtgcgaaagaggggattgccgttgccaaatgg
gcctcaaaattgggatggcctctgttaggtgatgtgttatcacaaactggacaaccacta
ccttgtgctgatttatggctaaataatccacaagtgaaggctgaattaaaccaagcagaa
atagtgatccaatttggctctagtttaacaggcaaacgcttattacaatggcaagcgaat
tgctcaccgcaaatgtattgggtgattgatgctattccgggacgtttagatccggggcat
catcaaggggagaaatttaccttatccccgagtcaatggttaacggcacatcctgctatt
gataatttaccttgggcgttgtcattaagtcatattgctacacaaacttatcaacatgtt
actgaagtaacagactattttggtgaagcacaagttgctcatcagttagatcatttactt
cctcacaatggccagctttttgttggcaatagtttaattgtgcgcttaattgatgctttt
gcacaattgccacagggctatcctgttatgagtaatcgtggtgctagtggcattgatgga
ttactttcaacctcagcaggtgttcatcgagccactcaaaaaccgacgttaactatcttg
ggtgatttatcggcattatatgatttaaatagtttggcactacatcaacaagtctatgcc
ccaaatgtggtgattatcgtcaataacaatggtgggcagatattctctatgttaccgacg
cctatggcagagcgggagcgtttttactgtatgccccatgctttaaattttaaacatgct
gctgccatgtttggtttagattatgttgcaccaaactgttgggatgatctgtttactaca
gtgactgcatgttggcagggggaagccaaaacaacattaattgaattgattgtcaatgaa
actgagggtgctgaaaccttaaatcagttggtaaaacaggtaaccgcttatgactttagc
ttgtag
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