Petromyzon marinus (sea lamprey): 116945016 Help Entry 116945016         CDS       T09614                                  Symbol HMCN1 Name (RefSeq) hemicentin-1 isoform X1   KO K17341   hemicentin Organism pmrn  Petromyzon marinus (sea lamprey) Brite KEGG Orthology (KO) [BR:pmrn00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04990 Domain-containing proteins not elsewhere classified [BR:pmrn04990]     116945016 (HMCN1) Domain-containing proteins not elsewhere classified [BR:pmrn04990]  EGF-like domain-containing proteins   hEGF / cEGF domain-containing proteins    116945016 (HMCN1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 Ig_2 ig V-set C2-set_2 EGF_CA VWA_4 TSP_1 G2F cEGF TSP1_spondin BiPBP_C C1-set GBD_Hemicentin FXa_inhibition EGF_3 TSP1_CFP_C VWA7_4 TSP1_ADAMTS hEGF MecA_N Motif Other DBs NCBI-GeneID:  116945016 NCBI-ProteinID:  XP_032814957 UniProt:  A0AAJ7WYY8 LinkDB All DBs Position 22:complement(10703491..11001701) Genome browser AA seq 5727 aa AA seqDB search MQSGCAQFRGLRSWLLLLLALGASLRPRVAWGQEDDEVIINRDEVGSPTADGKGQPEIPE GASTLAFVFDVTGSMYDDLVQVIEGASKILETSLNRPKKTLYNFALIPFHDPEIGPVTIT TDPDKFQRELRDLYVQGGGDCPEMSIGAIKIAVEISLPGSFIYVFTDARSKDYKLAPEVL QLIQQKQSQVVFVLTGDCGDRSHIGYKAYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQ ASKVHILSTDHESSDQNTWQIPFDPSLKEVTVSLSGLSPSIEIRDPSGKLMKKGAGLTEL LHIPNSAKVVNIKDPAPGLWTIKIGSNGRHSLRMTGLSTIDFRAGFSKKPTMDFKSTSNR PVQGIPTFVLLNTTGLEPHARVDRLELLSTAGRSLKTLPVRYHPLRRPFNIWNVTEFVPP AESFFLRVTGYDRDGYRFQRVSGVSYSSIVPEAPKVSMPVRTPGYYLQTGYIPCTVDSLI PFTLRFSKDGVRLGVDQFFKETAEATWELPRVSGVDEGFYECVAVSATGTGRARTYLDVT EPPPTIRAPLNVTVVPGEHAVLTCLVLSTVPYNLTWARGGGDAAAEPRVRVLANQSLEVR AVQLADGGAYECVAANEGGVASASAWLVVQEPPRAVVSPLNQTFRAGGEVHIGCTASGYP APLIVWTHNEMFIMNTGRHMVDQEGSLTIRDTVRRDAGTYGCLASNAAGTDKRTSLLIYI EAPKITVPREEILIANGDTSVLECQATGVPEPVVKWYKGDLELKSMPFLEIDTRRGTLTI QGTQEPDAGDYTCEATNEAGDARATVSLDVGSGPVFSQAPSDTTVEIGLNVTLPCLAFGY PEPRVTWHRADGRSLTSRDPWVPGATSQLQDGSLYIAGAWVDDEGLYVCEVENQFGKLEA QAYLTITGMVSPVIAVSPPVVNVLEGQLLTLPCVFLSGNPLPKRTWFKNGNVYAPEKVRA DGSVHVEGTSLGDAGEYVCMATNVAGSFNKSVAVNVHVMPSIQPASPIASTVEGVSITLP CKADGVPKPTISWTKGKDPIPHSSRRLVTDASGSLTIASPTGDDAATYVCTASNAAGSAS REVQLSVYVKPKINGTGRSGVPTEISVVAGEDVTLPCEVHSVPPPIVTWAKDRHPVSLAS ARHSLLPTGSLRVLETRVTDSGTYMCVATNIAGNITQAIKLSVLVPPAIQPGPRIVKVLL GETAELPCVAYGEPAPDIAWFRGESQLGSDGSAATKGPEGSLAIAAARLADAGTYTCVAS NSAGRDQTEIRLEVQEPPAVVDVGPPFNDFFQERVANQRIAFPCPAKGTPKPVIRWFRNG RELTGREPGLSIAEDGTLLVIPSVTPFDDGEYTCTASNEAGTTERKYQLKVHVPPKIEES DSRGNISVVLKQPVDLQCEVSGHPTPAITWLKNGLQVIESSDVRVVNGGKTLRLLRAQTD DEGAYACKAFNVAGESDKHFQLHVLVPPSIQGSGVPQDLNVVLNNGITLECKTSGVPAPL IQWYKDGKLLGANDLNLELSRKGQLLRIKAARLSDQGQFTCAASNPAGKQTREFKLSVYV PPSIRGADDGTSDATVLLDATALLECEARGVPLPAVTWLRDGRPLGPSGPEHAYVERGRF LRIPRARVAHAGRYTCRAVSAAGSAEKNYDLDVHVPPSISGEGDRPEKKKVVLGRPLVLE CEAAGHPAPTIAWLKDGVALPPGGGDGVLITLAGRRLEVASAGEGDGGRYVCVASSAAGR QERPYDVDVLVPPTLTGGDEGGENSVVVGSPLELECQASGTPEPRITWLKDGRPLKEGEG ARASADGRRLTVPRAQVADTGRYACVASNEAGDDRREFDVTVMVPPTIRVMGPSERAVVL GKSITLQCVSSGIPTPQVSWLKDGRPVGTTAGANVKVEGGGRMLQVSGAAREDAGRYTCV ATSAAGEAQQGVRLHVHEPPSIEGSGVRHNTTVIVNNPVEMECVASGSPTPVVSWQKDGR AIAGAGQGTPPPGVALLSRGRVLRLESAQVADTGRYTCLATNVAGRTELMHSLQVHVPPS IAGGTDTVAVVVNNPVRVECEARGIPAPTLTWLKDGSPISPLTSNGMQILSGGRILALSS AQISDTGRYTCVAINAAGEEQRDIDLRIYVPPNIMGEEQNVSVVLNQPVRMECRSNAIPP PTLTWLKDGRPLLKKPGLTVSEDGSTVQIDSAQVMDTGRYTCEATNVAGKTEKNYNVNVW VPPSVRGAGEPSQLNVIEGNMMSLVCESTGIPPPALSWRKNGKPLEGDQEGRVRVLSGGR LLQIGSARPSDAASYTCVASNVAGTSMRDFSLQVYVRPSIQQSGGRPTEVTVSRGGDVTL ECRVEGLPRPAVSWLKDGRPIPAAARRGGAGTGAAAAAMAKEAAGGPFVLNDGRTLQIHG AQVGDTGRYTCIAVNVAGQADRKFDLNVHVPPSIGDGEAENVSVVLGSPVAMTCEVSGIP PPSISWLFNRKPIPPGSDIRVLSGGRMLRVMHAHAGLAGRYTCIASNSAGEASKDFVLDV LLPPTIKDNEVVEDVKVKKGHKVTLTCEVEGNPTPTVRWLKDGQPLLEGDAEEDGEGEEK EGRRTIVSRGRFLQIMDARVGDTGRYTCVASNEAGARTKNYNLNVLVTPTIPGAGPDAGP QDVTVILNSPTTLVCEAQAYPAPTLTWLKDGLPVQANSNVRILPGGRTLQILNAGAEDAG RYTCVATNEAGETLKNYEVKVYIPPSINKDDNPGVGLSPKEIKLKVNNSLTLECEATAVP VAVLRWYKDGQQISSGEHLEIMASGRILKIKNAQVSDTGRYTCVATNLAGEDEKEFDVNI QVPPAFQKPAGSGRGGTDAGRPDGKDVVINNPISLYCETNAVPPPMLTWYKDGRPLSSSD RVLILPGGRVLQIPRAQVEDAGRYTCVAVNDAGEDSLSYDVRVLVPPSVRGGAGEAPEEV AVTVNATARLDCAVDGSPAPSVSWLKDGRPVSADGRHSLLFGGKTLQIERAQVMDTGRYT CVAENSAGRAEKLFNLNVHVPPAIVGTNPESLHVVVDNPISLMCEATGFPPPTLGWVKDG RPLQPSKSLFILPGGRILQIQRAKLSDGGRYTCVAINAAGQAKKHVVLTVYVPPTIRDGG GEAPLVVSVRAGGSVSLECESNAVPPPVVTWYKNGRPLAESEKAVLRGDGGHVLTLVDAE VADAGQYVCKATNVAGQVDKVFHLTVHVPPSIEGPPEEDASEIIGNPVTLACDALGIPPP AITWLHNGRALENAASLEMRILSGGSKLQIIRSQLSDAGRYTCVASNVEGEARKTYQLTI HVPPSIEGSELSSEVASVVNETVSLACKASGTPPPALHWLRDGKRLDGVAVSKDSSVLTL SAVQTSDAGKYTCVATNVAGEEDKIFNLNVFVPPSIEGAGQVEELSVVLDGSLSMECVAV GVPPPQITWMKNGLPLPLSAHVRLLSGGQTLRIVRAQVADAGTFSCVASNRAGVADKHYN LEVHVPPSLDNAGGTEELTVVRGTAVSVSCEASGSPPPAVTWLKDGEPLSLGPHVRPSAQ GMIITFSKARLEDTGRYTCVVSNQAGELSKHFNLKVLDPPRILGEGEGPREHSVVAGKSL ELECVAQGVPPPKLTWLRDGRPLPAGDGVRVLRGGQVLRIASAQVEDTGRYTCLASSAAG DDDREYLVRVHVPPNIAGAGGPQDLTVLLNGQLTLECKSDAVPPPTLSWLKDGNPLQGSA RLRLLSASRYLQINNAEPGDAARYTCVASNVAGNTQRQFNVAVHVVPSIREGPGAVTVLA ESDALLECVASGTPAPRVTWRKDGAVLSPGNSRYVFLEDGSLRVLASKVSDTGRYLCLAT SPAGSERRRVDLQVHLRPSIAAGPTNVTVVVNVQTTLACEASGIPKPEVTWLKNGRPLNT DSNQNMYRVLSSGSLVIISPSVEDTGRYRCSAQNEAGADEREMDLTVQVPPSIADEAAEL VVTKLSPALLTCHASGVPEPTLHWSKDGVRLPLRGEGYSVLPTGTVEITAALLHHAGKYV CHVSNAAGSAKRHVSLVVHEAPVIKAPPSQMEVIVNYPITLPCEARGTPQPTITWQREGI NVITSGEGFTVLPSGGLQIARAAVEDGGTYMCVAQNLAGTALGKVKLRVQVPPSILPHAA ELVVMADRTVTLPCNAEGSPTPVISWLKDGRPLGVEAPSSPATAAAAAAGGEGGAAVRRR VLASGALQIAFARRSDAARYTCTAANAAGSASSHTKLVVHVPPSVREGAAQLTVLEHGRL ELTCAVDGLPEPTVSWEREGRALHDTPGKYALLQGGTLALEKATPADAGDYTCVAVNAVG RDSRATLVSVHVPPAFTELPGDVSLNKGERLVLGCTATGIPTPSITWSFNNNILPVTPSN ANGRSELVVDGVSKSDGGTYTCTATSAVGSVRALGSVYVKEPPIFDGDVITNRIEPLGGN AILNCEVRGDPAPVIRWNKQGVPVTVGNRVRQLSNGSLAIYGTVNEDAGDYKCVATNDAG VVQKMVTLTLQRAPTFSVEPTDTVVDAGSVAALRCSADGEPPPAVEWTRRGGRPLRLDGR VTAAPDGSLRLAPARKDDTDEYECVARNLLGSALVRATLTVQVHGGFSEWLEWGPCSTSC GQGLQERVRVCNSPIPANGGRPCAGAASDSRPCASRPCPVDGGWSDWSPWEECSRSCGQG NRTRTRTCGNPPAQHGGRACEGRPLERILCNARPCPVAGNWGAWQPWGVCSAACGEGTQT RLRLCNEPPPAYDGPSCPGADTQTQVCSARKCPVDGKWSVWSGWGPCSVSCGGGSRQRSR SCSEPPPQHGGHPCEGSDIHVDFCNSEPCPVHGNWAPWSGWGPCSRSCNGGQARRHRTCD NPRPASGGRACVGSDSQMQQCHGEPCAVDGGWGPWQAWAPCSASCGGGGEQERVRRCESP PPTHGGRACQGDGSQVAKCNSQPCPGGPQRARGSVVGTLNDVELGMALMHVNMSDGGQGA RVIDGHIGNVPRAVGPAMRKLVSILSPVYWATAHEVGGAVNGYTLTNGLFRRETQVEFAT GEVVKMSHVARGVDSEGVLLLDVVLSGYLPSVAASADVALKDYNEDYIQTGPGLLYAHST RLYTVDGTTIPYSWNHTVLYDGALGKMPFLVETLHVTDAGARYDPRSERLSYALHAHIAK GERSNQCPQGFSLDTTGPYCADEDECAGSNPCSHTCHNTVGTYYCSCPRGLTISADGRTC QDIDECTLGGHNCPASQECENLMASFRCVVRCGVGFRRTHDGASCQDINECKETHPSPCN QKCVNLIGSYRCACEPGFQLRGRRCYDINECLQHACRADQQCRNTRGGYKCIDLCPNGMT KAENGTCVDVDECQEGTHQCRYNQICENTRGSYRCTCPRGYRSQGVGKPCLDIDECGSFP RPCAYRCVNTPGSFECLCSPGQRLLGDGKSCAGLERLPNNDDGGGGGVRRPFPRGHALGG PGPAAGVWSGDSATGDFTFVRQSARARYRGTGGRAAAATAARIRSRRATACLPGYRPFGG ECVDVDECQNKEQCQHECRNSPGSYQCVCPGGYRVAPNGKTCQDIDECLEQNVQCGPNRM CFNMRGSYKCIDTPCPPNYKRESRSGFCLKSCPPNDVECLLSPLALEYKLVALPFGIPSN QDLVRLVAYTQDDVMHPRTRFFVVDPDPSVPFAIRDEGGKGVVFTIRALREAHTYSMKVR ALSYAEDGSVEYQTTFIVYISVSAYPY NT seq 17184 nt NT seq  +upstreamnt  +downstreamnt atgcagagcggctgtgcccaattcaggggcctccgcagctggctcctgctcctcctggca ctcggcgcttccctgcgaccccgcgtcgcgtggggtcaggaggacgatgaggtgatcatc aacagggacgaggtgggcagtcccacggccgacgggaaggggcagcccgagatcccagag ggggcatcgacgctcgcgttcgtcttcgacgtcaccggctccatgtacgacgacctggtg caggtgattgagggggcctccaagatactggagacgtctctcaaccggcccaagaagacc ctgtacaacttcgctctcattccctttcacgaccccgaaatcggccccgtgaccatcacc acggacccggacaaattccagcgggagctcagggacctttacgtccagggtgggggggac tgccccgagatgagcatcggtgccatcaagattgccgtggagatctccctgccgggctcc ttcatctacgtcttcactgacgcccggtccaaggactacaagctggcgcccgaggtgctg cagctcatccagcagaagcagtctcaggtggtgttcgtcctgacgggcgactgcggagac cgtagccacatcggctacaaggcctacgaggagatcgcctccaccagctcgggccaggtc ttccacctcgacaagaagcaagtgaacgaggttttgaaatgggtcgaggaggctgtgcaa gcttccaaggtgcacattctgtccacggaccacgagtcaagcgaccagaacacgtggcag atcccgtttgatccgagcctcaaggaggtcacagtctccctcagcggcctgtctccctcc atcgagatccgggacccgtcaggcaagctcatgaagaagggagccggactcacagaactg ctgcacattcccaactcagccaaggtggtgaatatcaaggaccctgctcctggcctctgg acaatcaagattggaagcaatggaagacactcgctccgaatgacagggctcagcaccatt gacttccgtgccggattttccaagaaaccgacgatggacttcaagtcgacctcgaatcgc cccgtacaaggcatccccacgttcgtgctgctcaacacgacgggcctggagccgcacgcg cgcgtcgaccgcctggagctgctgagcacggcgggccggagcctcaagacgctgcccgtg cgctaccacccgctccggcggcccttcaacatctggaacgtcaccgagttcgtgccgccc gccgagagcttcttcctgcgcgtcacgggatacgaccgcgacggctaccgcttccagcgc gtgtcgggcgtctcctactcgagcatcgtgcccgaggccccgaaggtgagcatgcccgtg cgcacgcccggctactacctgcagacggggtacatcccctgcaccgtggacagcctcatc cccttcaccctgcgcttcagcaaggacggcgtgcgcctcggagtcgaccagttcttcaag gagacggcggaggccacgtgggagctgcctcgggtgtcgggagtggacgaggggttctac gagtgcgtggccgtcagcgccacgggcacggggcgtgcgcgcacctacctcgacgtcaca gagcctccgcccacgatccgcgcgccgctcaacgtgacggtggtgccgggcgagcacgcc gtgctcacgtgcctcgtgctcagcacggtgccctacaacctgacgtgggcgcgcggcggc ggcgacgcggccgccgagccgcgcgtgcgcgtgctggcgaaccagtcgctggaggtgcgc gcggtgcagctggcggacggcggggcctacgagtgcgtggcggccaacgagggcggcgtc gccagcgcgtcagcgtggctcgtcgtgcaggagcctccgcgggcggtggtgtcgcccctc aaccagacgtttcgcgccggtggcgaagtgcacatcggctgcacggcatcgggctacccg gctccgctgatcgtgtggactcacaatgagatgttcatcatgaacacgggcaggcacatg gtggaccaggagggctccctgacaatcagagacacggtgcggcgcgacgccggcacgtac ggctgtctggccagcaacgccgcgggcaccgacaagcggacgtccctgctcatctacatt gaggcccccaagatcacggttcctcgtgaagagatcctgattgccaatggagacacgtct gtgctggaatgccaggccactggtgtgcctgagcctgttgtcaagtggtacaaaggagac ctggagctgaagagcatgccgttcctggagattgacacgcggcgtggcacgctcaccatc cagggcacgcaggagcccgacgccggcgactacacctgcgaggcgaccaacgaggccggt gatgcccgggccacggtctccctggacgttggatctgggccggtgttctcccaggctccg tcggacaccaccgtggagatcgggctcaatgtgacgctgccgtgcctggcgttcggctac ccggagccgcgcgtcacgtggcaccgagcggacggtcgcagcctgacgtcacgtgacccg tgggtgccgggcgccacctcccagctgcaggacggcagcctctacattgcgggtgcctgg gtggacgacgaaggtctgtacgtgtgcgaggtggagaatcagttcggaaaacttgaggct caagcttacctcaccatcacgggcatggtgtctcccgtgattgccgtgagcccgccggtg gtgaacgtgctggaagggcagctgctcaccctgccctgcgtcttcctctccggaaacccg ctgcccaagcgcacgtggttcaaaaatggaaacgtgtacgccccggagaaggtgcgggcc gacgggagcgtgcacgtggagggcacgagcctcggggacgccggcgagtacgtgtgcatg gccaccaacgtggccggctccttcaacaagtccgtcgccgtcaacgtgcacgtcatgccg agtatccagccggcgtcgcccatcgcgagcactgtggagggcgtctccatcaccctgccc tgcaaggccgatggagttcccaagccgaccatcagctggaccaagggcaaggaccccatt ccgcacagcagcaggaggctcgtgacggacgcgagcggcagcctcaccatcgcgagcccc acgggggacgacgcggccacctacgtgtgcacggccagcaacgcggccggctcggccagc cgagaggtgcagctatcggtctacgtcaagcccaagatcaacgggacggggcggtcgggg gtgcccacggagatttccgtggtcgctggcgaggacgtcaccctgccgtgcgaagtgcac agcgtgccccctcccatcgtcacctgggccaaggaccggcaccccgtgtcgctcgcctcc gccaggcattctctgctgcccactggctccctgagggtgctggagactcgcgtgacagac agtggcacttacatgtgcgtggccaccaacattgctggtaacatcacccaggccatcaag ctctccgtcctagtgccccccgcgatccagccgggcccgcgcatcgtcaaggtgctgctg ggggaaacggcggagctgccgtgcgtggcgtacggggagccggcgcccgacatcgcgtgg ttccgtggcgagagtcagctgggctccgacggctccgccgccaccaagggccccgagggg tctctggccatcgccgccgctcgcctcgccgatgccggcacctacacctgcgtggcctcc aactcagccggccgcgaccagacagaaatccgcctggaggtccaggagccaccggccgtt gtcgacgtgggaccccccttcaatgatttcttccaggagcgcgtggcaaaccagcgcatc gcattcccgtgccccgccaaaggaaccccaaagccagtgatccgttggttccggaacggc cgcgagctgacaggccgcgagccggggctgtccatcgcggaggacggcacgctgctcgtc atcccgtccgtgacgccattcgacgacggggagtacacatgcacggcgagcaacgaggcc ggcaccaccgagcgcaagtaccagctcaaggtccacgtccctccaaaaattgaagagagc gattcgcgggggaacatctcggttgtgctcaagcagccagtggacctgcagtgtgaagtc tccggacacccgacgccggccatcacgtggcttaaaaacggcctgcaggtgatcgagagc agcgacgtgcgcgtcgtgaacggaggcaagacgctgcgcctgctgcgtgcgcagacggac gacgagggcgcctacgcctgcaaggcgttcaacgtggccggggagagcgacaagcacttc cagctgcacgtgctggtgccaccgagcatccagggctccggcgtcccccaggacctcaac gtggtcttaaacaacgggatcacactggagtgcaagaccagcggtgtacccgccccgctg atacagtggtataaggatggcaagctgttgggggcgaacgacctgaacctggagctgagc aggaagggccagctgctgcggataaaggcagctcgtctgtcggaccaggggcagttcacg tgtgcggcatccaaccccgccggcaagcagaccagggagttcaagctctccgtgtacgtt cccccgagcatccgcggcgccgacgacggcacgagcgacgcgacggtgctgctggacgcg acggcgctgctcgagtgcgaggctcgcggcgtgcccctgccggccgtcacctggctgcgg gacggccgcccccttgggccctcggggcccgagcacgcgtacgtggagcgcggccgcttc ctcaggatcccgcgggcgcgagtggcgcacgccgggcgctacacgtgccgcgccgtcagc gcggcgggcagcgccgagaagaactacgacctggacgtgcatgtgccaccgtccatttct ggcgagggcgaccgtcccgagaagaagaaggtggtgttgggtcgcccgctggtgctggag tgcgaggcggccggccaccccgcgcccaccatcgcgtggctcaaggacggcgtggccctg ccgccgggcggcggggacggcgtgctcatcaccctggcaggccgcaggctggaggtggcg agcgccggggagggcgacgggggccgatacgtgtgcgtcgcgagcagcgccgccggacgg caggagaggccttacgacgtcgacgtgctcgtgccgcccacgctgacgggaggagacgag ggcggcgagaacagcgtggtcgtcggctctccgctggagctcgagtgccaggcgagcggc acccccgagccccggatcacgtggctgaaggacgggcggcccctcaaggagggcgaggga gcccgcgcgtcggccgacggacgcaggctcacggtgccgcgcgcccaggtggccgacacc ggccgctacgcctgcgtggcctccaacgaggccggggacgaccgcagggagttcgacgtc accgtcatggtgccgcccacgatccgcgtgatggggccgagcgagcgagccgtcgtgctg ggcaagtccatcaccctgcagtgcgtgtccagcggcatccccacgccacaggtgtcctgg ctcaaggacggccgccccgtcggaacgacggcgggggcgaacgtcaaggtggagggtggc gggcgcatgctgcaggtgagcggggccgcgcgcgaggacgccggccgctacacctgcgtg gccaccagcgcggccggggaggcgcagcagggggtgcgcctgcacgttcacgagcctccg agcatcgagggcagcggcgtgcgccacaacaccactgtgatcgtgaacaacccagtggag atggaatgcgtggcgagcggcagccccactccagtggtgtcgtggcagaaggacgggcgg gccatcgccggcgccgggcaggggacgcccccgccaggcgtggcgctgctgtcccgcggc cgcgtgctccgtctggagagcgcccaggtggccgacacgggccgctacacctgcctggcc accaacgtggcgggccgaaccgagctcatgcacagcctgcaggtccacgttcccccgagc atcgcgggaggcacggacacggtggcggtggtggtgaacaaccccgtgagggtggagtgc gaagccaggggcatccccgcacccacgctcacctggctcaaggacgggagccccatctcc ccgctcacctccaacggcatgcagatcctgtcaggagggaggatcctggccttgtccagt gctcagatatcggacaccggccgctacacatgtgtggcgatcaatgctgccggagaggaa cagagagacatcgatctgcgaatctacgtgccgcccaacatcatgggcgaggagcagaac gtgtcggtggtgctgaaccagccggtgcgcatggagtgccgcagcaacgccatcccgccg cccacgctcacgtggctcaaggacgggcggcccctgctcaagaagcccggcctcaccgtg tccgaggacggcagcacggtgcagatcgacagcgcgcaggtgatggacacggggcgctac acgtgcgaggcaaccaacgtggccggcaagacggagaagaactacaacgtcaacgtgtgg gtccccccgagcgtgcgtggcgccggggagcccagccagctgaacgtcatcgagggcaac atgatgagcctggtgtgcgagtcgacgggcatccctccgcccgcgctctcctggagaaag aatggtaaacccctggagggtgaccaggagggccgtgtgagggttctgtctggagggcgg ctcctccagatcggcagcgccaggccgtcggacgccgcctcctacacgtgcgtggcctcc aacgtggccggcaccagcatgagggacttctctctccaggtgtacgtgcgcccgagcatt cagcagagcggcgggcgtcccacggaggtgacggtgtcgcgcgggggcgacgtgaccctc gagtgccgcgtcgagggcctgccccgtccggccgtcagctggctcaaggacggccgcccc atcccggccgctgcccgcaggggcggcgcgggaacgggggcggcggccgcggcgatggcc aaggaggcggccgggggccccttcgttctcaacgacggccgcaccctgcagatccatggc gcccaggtgggcgacacggggcgctacacctgcatcgccgtcaatgtggccggacaggcc gaccgcaagttcgacctcaacgtgcacgtgccaccatcaatcggggacggcgaggcggag aacgtgagtgtggtgctggggagccccgtggccatgacgtgcgaggtgtcgggcatccca cctccgtccatctcctggctcttcaaccgcaagcccattcccccgggcagcgacatcagg gtgctctccggcggacgcatgctgcgggtgatgcacgcgcacgctgggctggccgggcgg tacacctgcatcgcgagcaacagcgcaggggaggccagcaaagacttcgtgctggacgtg ctgcttccaccaaccatcaaagacaacgaagtggtggaggacgtgaaagtcaagaaaggt cacaaggtcacactgacctgcgaggtagaaggtaacccaacaccaaccgtgcgttggctt aaggatggacagcccctgctggagggagacgcggaggaggacggcgagggtgaggagaag gagggacgacgcacgatcgtctccagaggccgcttcctgcagatcatggatgcgcgtgtg ggcgacaccggccgctacacgtgcgtggcctccaacgaggccggggcccggaccaagaac tacaacctcaacgtcctggtgacgccgacgatcccgggagccgggcccgatgcggggcct caggacgtcacggtgatcctcaacagccccacgaccctggtgtgcgaggctcaggcctac ccggcgcccacgctcacctggctgaaggacggcttgcccgtgcaggccaacagcaacgtg cgcatactacccggggggcggacgctgcagattctgaatgccggcgcggaggacgcgggc cgctacacctgtgttgccaccaacgaagccggggagactctgaagaactacgaggtcaag gtctacatcccgccctccatcaataaagatgacaacccaggggtgggtctcagccccaag gagatcaagctcaaggtgaacaactccctgacgctggagtgcgaggcgacggcggtgccg gtggccgttctgcgctggtacaaggacggccagcaaatcagcagcggcgagcacctggag atcatggccagcggtcgcatcctcaagataaagaacgctcaggtgtcggacacgggccgc tacacctgcgtggccaccaacctggcgggcgaggacgagaaggagtttgacgtcaacatc caggtgcctcccgcgttccagaaaccggcggggtccggccgtggcggaacggacgcgggg aggcccgacgggaaggacgtggtcatcaacaaccccatctccctgtactgcgagaccaac gcggtgccgccacccatgctcacgtggtacaaggacggccgccccctctcctccagcgac agggtcctcatcctgccaggaggccgcgttctgcagatcccacgggcgcaggtggaggac gccggccgctacacgtgcgtcgccgtcaacgacgcgggcgaggactccctcagctacgac gtgcgcgtgctcgtgccgccgagcgtgcggggcggcgccggggaggcgcccgaggaggtg gcggtgacggtgaacgccaccgcccggctagattgcgccgtcgacgggagcccggcgccc tccgtctcgtggctcaaggacgggcggccggtctccgcggacggcagacactccttgctg ttcggcggcaagactcttcagattgagcgtgcgcaggtgatggacacgggacgttacacg tgcgtcgctgagaattccgccggtcgggcagagaagctgtttaacctcaacgtccacgtg ccaccggcgatcgtgggaacgaacccggaaagcctccacgtggtggtggacaaccccata tcgctcatgtgcgaggccacgggatttcccccgcccacgctcggctgggtcaaggacggg aggcccctgcagccaagcaagagcctcttcattcttcccggcggtcgcatcttgcagatc cagagggcgaagctgtccgacggcggacgctacacctgtgtggccatcaatgccgcgggc caggccaagaagcacgtggtgctcaccgtgtatgtaccccccacaatccgcgacgggggc ggtgaggcccccctcgtggtcagcgtgcgagcgggaggctccgtgtcgctcgagtgcgag tccaacgccgtgccgccccccgtggtcacgtggtacaagaacggccgccccctggcggag tcggagaaggccgtgctgcgcggggatggaggacacgtgctgacactcgtggacgcggag gtggccgatgccgggcagtacgtgtgcaaggccaccaacgtggccgggcaggtggacaag gtcttccacctcaccgttcacgtgccgccgagcatcgagggcccgccggaggaagacgcg agcgagatcatcggcaaccccgtgacgctggcgtgcgacgccctgggcatcccgccgccg gccatcacgtggctgcacaacggccgtgctttagagaacgcggcgtcgttggagatgcgc atcttgtcgggcggcagcaagctgcagatcatccgctcgcagctgtcggacgccgggcgc tacacgtgcgtggcttccaacgtggagggggaggcacgcaagacctaccagctcaccata cacgtgccgcccagcatcgagggctcggagctgtcgagcgaggtggcgtcggtggtgaac gagacggtgtcgctggcgtgcaaagcgagcggcactccgccccccgcgctgcactggctg cgcgacggcaagcgcctcgacggagtcgcggtctctaaggacagcagcgtgctcacgctg agcgccgtgcagacatccgacgccgggaagtacacgtgtgtcgccaccaacgtggccggg gaggaggacaagatcttcaacctcaacgtgttcgtgccgccatctattgaaggcgcgggg caggtggaggagctgtccgtggtgctggacggctcgctgagcatggagtgcgtggccgtg ggggttccgccgccccagatcacgtggatgaaaaacggacttcccctgccgctctccgcc cacgtgcgcctcctgtctggggggcagactctccggatcgttcgagcgcaagtggcggac gcggggacgttctcctgcgtggcgtcgaaccgcgccggcgtggcagacaagcactacaac ctggaggtgcacgttccgccgagcctggacaacgcgggcggcacggaggagctgacggtg gtgcgcggcacggctgtgtcggtgtcgtgcgaggcgagcggcagccccccgccggccgtc acgtggctcaaggacggcgagccgctctcgctcggcccgcacgtccgcccgtccgcgcag ggcatgatcataacgttcagcaaggcccggctggaggacacgggccgctacacgtgtgtc gtgagcaaccaagcgggagagctcagcaagcacttcaacctcaaagtcctcgacccgccg cgcatcttgggcgagggcgagggcccccgggagcactcggtggtggcgggcaagtctctg gaactggagtgcgtggcgcagggggtgccgccccccaagctcacgtggctgcgggacggg cggcccctgcccgcgggcgacggcgttcgcgtgctgcggggaggacaggtgctgcgcatc gcgagcgcgcaggttgaggacacgggcaggtacacctgcctggcgtccagcgcggcaggg gacgatgaccgagagtacctggtcagggtgcacgttccaccgaacatcgccggcgccggc ggcccccaggacctcacggtgctgctcaacgggcagctgaccctcgagtgcaagtcggac gccgtaccgccccccacgctcagctggctcaaggacggcaatcccctgcagggctcggcg cgcctgcgactgctctccgccagccgctacctgcagatcaacaacgcggagccgggcgac gcggcgcgctacacctgcgtggcgagcaacgtcgccggcaacacccagcgccagttcaac gtggccgtgcacgtggtgccgagcatccgggaggggccgggcgcggtgacggtgctggcg gagagcgacgcgctgctcgagtgcgtcgcgagcggaacgccggcgccacgcgtcacctgg aggaaggacggagccgtgctgtccccgggcaactccaggtacgtgttcctggaggatggc tccctgcgcgtcctggcgagcaaggtctcggacacgggacgctacctgtgcctcgccacc agcccggctggctccgagaggcggcgcgtggacctgcaggttcacttgcggccgtccatc gcggccggccccaccaacgtcacggtggtggtgaacgtgcagacgacgctcgcgtgcgag gcctcgggcatccccaagcccgaggtcacgtggctcaagaacgggcggcccctcaacacg gactccaaccagaacatgtacagggtgctgtcgtcaggctccctggtgatcatctcgccg tccgtggaggacacgggccgctaccgctgctcggctcagaacgaggccggagccgacgag agggagatggacctgacggtgcaggtgccgccctccatcgcggacgaggccgccgagctc gtggtgaccaagctgtcgccggcgctgctcacgtgccacgcgtccggcgtccccgagccc acgctgcactggagcaaggacggcgtgcggctgccgctgcgcggggagggctacagcgtt ctgccgaccggcacggttgagatcaccgcggcgctgttgcaccacgccggcaagtacgtg tgccacgtgagcaacgcagccggctccgccaagaggcacgtcagcctcgtggtgcacgag gctccggtcatcaaggccccgccgtcccagatggaggtgattgtcaactaccccatcacc ctgccgtgcgaggccagagggacgcctcagccaaccatcacctggcagcgagagggcatc aacgtgatcacgagcggagagggcttcacggtgctgcccagcggagggctgcagatcgcc cgggcggcggtggaggacggaggcacctacatgtgtgtggcgcagaacctggccggcacc gccttgggcaaggtgaagctccgcgtgcaagtgccgccctccatcctgccccacgctgcc gagctggtggtgatggccgaccggacggtcacgctgccctgcaacgccgagggctccccg acccccgtcatctcctggctcaaggacgggcggcctttgggagtcgaggccccttcgtct cccgccaccgccgccgccgctgctgccggcggggagggcggcgcggccgtgcggaggcgc gtgctcgcctcgggcgcgctgcagatcgccttcgcgcgtcgcagcgatgccgcccgctac acctgcacggccgctaacgcggccggctcggcgagctcccacaccaagctcgtggtgcac gtgcccccgagtgtccgtgagggtgcggcccagctcaccgtgctggagcatgggaggctg gagctgacgtgcgccgtggacggcctccccgagcccacggtgtcgtgggagagggagggc cgagcgctgcacgatacgcccggaaagtacgcgctgctgcagggaggcacgctcgctctg gagaaggcgacgccggcggacgcgggcgactacacgtgcgtggcggtgaacgcggtgggc agggactcgcgcgcgacgctcgtgagcgtgcacgtgccacccgcgttcaccgagctgccc ggcgatgtctccctcaacaagggggagcgcctcgtgctgggctgcacggccacgggcatc cccacccccagcatcacgtggtccttcaacaacaacatcctgccggtgacgccctcgaac gcgaacgggcgcagcgagctggtggtcgacggcgtctccaagtcggacggcggcacgtac acctgcacggccacgagcgccgtgggctccgtgagggcgctgggctccgtctacgtcaaa gagcctcccatcttcgacggggacgtgatcaccaatcgcatcgaacccctgggcgggaac gcgatcctgaactgcgaggtgcggggagacccggcaccggtcatccgctggaacaagcag ggcgtgcccgtcacggtgggcaaccgcgtgcgccagctcagcaacggctcgctcgccatc tacggcacggtgaacgaggatgctggcgactacaaatgcgtggcgaccaacgacgctgga gtcgtgcagaaaatggtcaccctgacgctgcaaagagctcccaccttctcggtggagccg acggacaccgtggtggacgcgggcagcgtggcggcgctgcgctgctcggccgacggggag ccccccccggcggtcgagtggacgcgacgcggggggcggccgctgcgcctcgacgggcgc gtgacagcggcgcccgacgggtccctgcggctggcgccggcgcgcaaggacgacacggac gagtacgagtgcgtggcgcgcaacctcctgggctccgcgctcgtgcgcgcaactctcacc gtgcaagttcacggcggcttctccgagtggctcgagtggggcccctgcagcacatcgtgc ggccagggactgcaggagagggtgcgcgtctgcaacagccccatcccggccaacgggggg cggccgtgtgccggcgccgcctccgacagccgcccctgtgccagccgaccctgtccagtg gacggcggctggtcggactggagcccctgggaggagtgctcgcgctcctgcggccagggg aaccgcacgcgcacgcggacgtgcggcaacccgccggcccagcatggcggccgggcctgc gagggccgccccctcgagcgcatcctgtgcaacgcgcggccttgccccgtggctgggaac tggggagcctggcagccgtggggggtgtgcagcgccgcgtgcggcgagggcacccagacg cgcctgcggctctgcaacgagccccctccggcgtacgacgggcccagctgcccgggcgct gacacccagacgcaggtctgcagtgcccgcaagtgtccagtcgacgggaagtggtccgtg tggagcggctggggcccctgctcggtgtcgtgcgggggcggctcccggcagcgctcgcgc tcctgctccgagccgccgccccagcacggcggtcacccgtgcgagggcagcgacatccac gtcgacttctgcaacagcgagccctgccccgttcacggcaactgggccccgtggagcggc tggggcccgtgcagccgctcgtgcaacggaggccaggcgcgacgccaccgcacgtgcgac aacccgaggcccgccagcgggggccgcgcgtgcgtgggctccgactcgcagatgcagcag tgccacggcgagccgtgcgccgtggacgggggctgggggccctggcaagcgtgggccccg tgctcggcatcgtgcggcggcggcggcgagcaggagcgcgtgcggcgctgcgaaagcccg ccgccgacccacggagggagggcctgccagggcgacggcagccaggtagccaagtgcaac agccagccgtgccccggcggcccgcagcgcgcgcgcggctccgtggtgggcaccctcaac gacgtggagctgggcatggcgctgatgcacgtgaacatgagcgacggcgggcagggcgcg cgcgtcatcgacggccacatcggcaacgtcccgcgggccgtcgggccggcgatgcgcaag ctcgtgtccatcctgtcccccgtgtactgggcgacggcgcacgaggtgggcggcgccgtc aacggctacacgctcaccaacggcctcttccgccgggagacgcaggtcgagttcgccacg ggcgaggtggtgaagatgtcgcacgtggcgcgcggcgtcgactcggagggcgtgctgctg ctcgacgtggtgctcagcggctacctgccgtccgtcgccgcctccgccgacgtcgccctc aaggattacaacgaggactacatccagacggggccgggcctgctgtacgcccactcgaca cgcctctacacggtggacggcaccaccatcccctactcgtggaaccacacggtgctctat gacggcgcccttggcaagatgcccttcctggtggagacgctgcacgtgacggacgccggc gcccgctacgacccgcgcagcgagcgcctctcctacgcgctgcacgcgcacatcgccaag ggggagcggagtaaccagtgtcctcagggcttctcgctggacacaacgggaccgtactgt gctgacgaggacgagtgcgcggggagcaacccatgctcgcacacgtgccacaacaccgtg ggcacctactactgctcctgcccgcgaggcctcaccatctcggccgatggccggacctgc caagacattgacgagtgcaccctgggcggccacaactgccccgccagccaggagtgcgag aacctcatggcctccttccgctgcgtcgttcgctgcggggtcggcttccgccgcactcac gacggcgccagctgccaggacatcaacgaatgcaaggagacccacccgtcgccctgcaac cagaagtgcgtcaacctcatcggcagctaccgctgcgcgtgcgagccgggcttccagcta cgcggccgccgatgctatgacatcaacgagtgcctgcagcacgcgtgccgcgcggaccag cagtgccgcaacacgcgcggcggctataaatgcatcgacctgtgccccaacggcatgacc aaggcggagaacggcacgtgcgtcgacgttgacgagtgccaggaaggcacccaccagtgc cgctacaaccaaatctgcgagaacacgcgggggagctaccgctgcacgtgccctcggggc taccgctcgcagggcgtgggcaagccctgcctggacattgacgagtgcggatcgttcccc cggccgtgcgcgtaccgctgcgtcaacacgcccggcagcttcgagtgtctctgctcgccc ggccaacgcttgctgggcgacgggaagtcgtgcgctggtctagagcgattgccaaataac gacgacggcggcggcggcggtgttcgccgtccctttccccggggccacgcgttgggcgga ccgggccccgccgctggcgtttggagcggagattcagccacgggcgacttcaccttcgtt aggcagagcgctcgcgcgcgttaccgtggcaccggcggccgtgccgccgcggcgacggcg gctaggattcggagccgtagggccaccgcgtgcctccctgggtatcgcccgtttggcgga gagtgcgtagatgtggacgagtgtcagaacaaggagcagtgccagcacgagtgccgtaac tcccccgggagctaccaatgcgtctgtcccggtggataccgcgtcgcccccaacggcaag acctgccaggacattgacgagtgtctggagcagaacgtacagtgcggacccaaccggatg tgcttcaacatgcgcggcagctacaagtgcatcgacacgccgtgcccgcccaactacaaa cgcgagtcgcgctcagggttctgcctcaagagctgccccccgaacgacgtggagtgcctg ctgagcccgctggcgcttgagtacaagctggtggcgctgcccttcggcatcccctccaac caggacctcgtgcgtcttgtcgcctacacgcaggacgacgtgatgcaccccaggacgcgc ttctttgtggtcgacccggaccccagcgttccgtttgcgatccgcgacgagggcggcaag ggcgtggtgttcacgatccgcgcgctgcgcgaggcacacacctacagcatgaaggtgcgc gccctctcctacgcggaggacggctccgtcgagtaccagaccaccttcatcgtctacatc tccgtctccgcctacccctactag

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